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MXPA05011826A - Metodo para detectar probnp con un anticuerpo monoclonal que se enlaza a los aminoacidos 41-46. - Google Patents

Metodo para detectar probnp con un anticuerpo monoclonal que se enlaza a los aminoacidos 41-46.

Info

Publication number
MXPA05011826A
MXPA05011826A MXPA05011826A MXPA05011826A MXPA05011826A MX PA05011826 A MXPA05011826 A MX PA05011826A MX PA05011826 A MXPA05011826 A MX PA05011826A MX PA05011826 A MXPA05011826 A MX PA05011826A MX PA05011826 A MXPA05011826 A MX PA05011826A
Authority
MX
Mexico
Prior art keywords
amino acid
monoclonal antibody
antibody binding
probnp
native probnp
Prior art date
Application number
MXPA05011826A
Other languages
English (en)
Inventor
Christoph Seidel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33427054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA05011826(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MXPA05011826A publication Critical patent/MXPA05011826A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invencion se refiere a anticuerpos que se enlazan a proBNP nativo, un metodo para deteccion especifica de proBNP nativo, un metodo para correlacionar el nivel de proBNP nativo para el diagnostico de insuficiencia cardiaca, un kit para deteccion de proBNP nativo y a una linea de celulas de hibridoma que produce un anticuerpo para porBNP nativo.
MXPA05011826A 2003-05-12 2004-05-12 Metodo para detectar probnp con un anticuerpo monoclonal que se enlaza a los aminoacidos 41-46. MXPA05011826A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03010591 2003-05-12
PCT/EP2004/005092 WO2004099253A1 (en) 2003-05-12 2004-05-12 Method of detecting probnp with a monoclonal antibody binding to the amino acid 41-46

Publications (1)

Publication Number Publication Date
MXPA05011826A true MXPA05011826A (es) 2006-01-26

Family

ID=33427054

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05011826A MXPA05011826A (es) 2003-05-12 2004-05-12 Metodo para detectar probnp con un anticuerpo monoclonal que se enlaza a los aminoacidos 41-46.

Country Status (16)

Country Link
US (4) US7264939B2 (es)
EP (4) EP2949669A1 (es)
JP (4) JP4430066B2 (es)
KR (2) KR20080011467A (es)
CN (3) CN101967190A (es)
AT (2) ATE517124T1 (es)
AU (1) AU2004235974B2 (es)
BR (1) BRPI0410261B8 (es)
CA (2) CA2522378C (es)
DK (3) DK1625164T3 (es)
ES (3) ES2372282T3 (es)
HK (1) HK1097855A1 (es)
HU (1) HUE025169T2 (es)
MX (1) MXPA05011826A (es)
PL (3) PL2256132T3 (es)
WO (2) WO2004099252A1 (es)

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FR2843396B1 (fr) * 2002-08-07 2005-04-15 Bio Rad Pasteur Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque
AU2004235974B2 (en) * 2003-05-12 2008-02-14 F. Hoffmann-La Roche Ag Method of detecting proBNP with a monoclonal antibody binding to the amino acid 41-46
US20070037208A1 (en) * 2003-05-29 2007-02-15 Foote Robert S Method for detecting cardiac ischemia via changes in b-natriuretic peptide levels
DE10355731A1 (de) 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
DE602005001299T2 (de) * 2004-07-07 2008-02-07 Roche Diagnostics Gmbh Kombinationen von Markern zum Nachweis von typ 1 und 2 Diabetes
AT500800B1 (de) * 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp
EP2498095A3 (en) 2007-01-25 2012-11-28 Roche Diagniostics GmbH Use of IGFBP-7 in the assessment of heart failure
KR100836322B1 (ko) * 2007-08-31 2008-06-09 현대자동차주식회사 차량용 흡음재 제작장치 및 방법
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid
CN102027374A (zh) 2008-04-30 2011-04-20 霍夫曼-拉罗奇有限公司 Sfrp-3在评价心力衰竭中的用途
WO2011012268A1 (en) 2009-07-27 2011-02-03 Roche Diagnostics Gmbh Use of mimecan in the assessment of heart failure
EP2568294B1 (en) * 2009-11-13 2015-01-07 BG Medicine, Inc. Risk Factors and Prediction of Myocardial Infaraction
AU2011285694B2 (en) 2010-08-04 2014-12-18 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
US8481333B2 (en) 2011-05-31 2013-07-09 Idexx Laboratories, Inc. Detection of degradation products of feline NT-proBNP
JP6119607B2 (ja) * 2011-09-20 2017-04-26 コニカミノルタ株式会社 検体希釈用液、それを用いたキットおよび蛍光測定方法
US20140273273A1 (en) 2012-11-01 2014-09-18 Christie Mitchell Ballantyne Biomarkers to improve prediction of heart failure risk
CN103304665A (zh) * 2013-05-21 2013-09-18 上海贝西生物科技有限公司 一种抗氨基末端脑利钠肽前体单克隆抗体及其应用
JP6682445B2 (ja) * 2014-10-10 2020-04-15 松森　昭 心不全患者の検出方法、心疾患の識別方法、心不全の検査試薬、心不全の検査キット、心不全を検出するための装置及び心不全を検出するためのプログラム
EP3360570A1 (en) 2017-02-13 2018-08-15 Roche Diagnostics GmbH Antibodies recognizing genetic variants
EP3657169B1 (en) * 2017-10-02 2023-05-03 Otsuka Pharmaceutical Co., Ltd. Method for detecting analyte
EP3779438A4 (en) * 2018-04-13 2022-01-26 Kyoritsu Seiyaku Corporation PROCEDURE FOR DETECTING HEART FAILURE, INSTRUMENT FOR DETECTING HEART FAILURE, SANDWICH IMMUNOASSAY PROCEDURE AND ANTIBODY COMBINATION
CN108752480B (zh) * 2018-05-30 2022-03-29 中元汇吉生物技术股份有限公司 一种免疫原组合物、其制备方法及其用途
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
CN111487222B (zh) * 2019-01-28 2023-11-14 上海乐合生物科技有限公司 一种检测bnp的spr芯片的制备方法
JP2022544394A (ja) 2019-08-13 2022-10-18 ゲンティアン アクティーゼルスカブ Ｎｔ－プロｂｎｐの定量のための高感度粒子増感アッセイ
CN116235056A (zh) * 2020-09-30 2023-06-06 豪夫迈·罗氏有限公司 心房颤动评定中的循环总NT-proBNP(糖基化和未糖基化NT-proBNP)及其与NT-proBNP(未糖基化NT-proBNP)的比率
CN112986586A (zh) * 2021-02-20 2021-06-18 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
CN112964885B (zh) * 2021-02-20 2022-11-11 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
JP2024538607A (ja) 2021-10-01 2024-10-23 ゲンティアン アクティーゼルスカブ サンプル中のｎ末端プロホルモンｂｎｐ（ｎｔ－プロｂｎｐ）の濃度を測定するための新規方法
WO2023175176A1 (en) 2022-03-18 2023-09-21 Roche Diagnostics Gmbh Cmybpc marker combinations for early discrimination of type 2 versus type 1 acute myocardial infarction
WO2023175152A1 (en) 2022-03-18 2023-09-21 Roche Diagnostics Gmbh Troponin marker combinations for early discrimination of type 2 versus type 1 acute myocardial infarction

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Publication number Priority date Publication date Assignee Title
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
JP2665850B2 (ja) 1991-11-14 1997-10-22 塩野義製薬株式会社 ｈＢＮＰのＣ端を認識するモノクロ−ナル抗体
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AU2004235974B2 (en) * 2003-05-12 2008-02-14 F. Hoffmann-La Roche Ag Method of detecting proBNP with a monoclonal antibody binding to the amino acid 41-46

Also Published As

Publication number Publication date
WO2004099252A1 (en) 2004-11-18
KR100857752B1 (ko) 2008-09-11
EP1625163B8 (en) 2011-11-02
US20070099241A1 (en) 2007-05-03
PL2256132T3 (pl) 2016-08-31
EP1625164A1 (en) 2006-02-15
EP2949669A1 (en) 2015-12-02
AU2004235974B2 (en) 2008-02-14
DK2256132T3 (en) 2015-07-13
EP2256132B1 (en) 2015-04-01
WO2004099253A1 (en) 2004-11-18
EP2256132A1 (en) 2010-12-01
ATE517124T1 (de) 2011-08-15
DK1625163T3 (da) 2011-12-05
US20070117156A1 (en) 2007-05-24
CN1784425A (zh) 2006-06-07
US7811770B2 (en) 2010-10-12
US7807380B2 (en) 2010-10-05
ATE522546T1 (de) 2011-09-15
US7264938B2 (en) 2007-09-04
JP4430066B2 (ja) 2010-03-10
JP2007535470A (ja) 2007-12-06
BRPI0410261B8 (pt) 2021-07-27
CN101967190A (zh) 2011-02-09
CN1832964A (zh) 2006-09-13
CA2522378A1 (en) 2004-11-18
ES2548327T3 (es) 2015-10-15
EP1625163B1 (en) 2011-08-31
JP2013018784A (ja) 2013-01-31
CN100497393C (zh) 2009-06-10
BRPI0410261A (pt) 2006-05-16
JP4834136B2 (ja) 2011-12-14
EP1625164B1 (en) 2011-07-20
JP2007525427A (ja) 2007-09-06
CA2522747C (en) 2012-08-14
AU2004235974A1 (en) 2004-11-18
JP5649631B2 (ja) 2015-01-07
HUE025169T2 (en) 2016-02-29
HK1097855A1 (en) 2007-07-06
US20060110776A1 (en) 2006-05-25
CA2522747A1 (en) 2004-11-18
ES2369008T3 (es) 2011-11-24
US20060110775A1 (en) 2006-05-25
JP5128125B2 (ja) 2013-01-23
CA2522378C (en) 2011-03-29
EP1625163A1 (en) 2006-02-15
DK1625164T3 (da) 2011-10-31
BRPI0410261B1 (pt) 2020-03-10
US7264939B2 (en) 2007-09-04
KR20060003905A (ko) 2006-01-11
PL1625163T3 (pl) 2012-01-31
JP2010011860A (ja) 2010-01-21
KR20080011467A (ko) 2008-02-04
ES2372282T3 (es) 2012-01-18
PL1625164T3 (pl) 2011-12-30

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