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PH22862A - Novel quinoline derivatives and method of use thereof - Google Patents

Novel quinoline derivatives and method of use thereof

Info

Publication number
PH22862A
PH22862A PH34426A PH34426A PH22862A PH 22862 A PH22862 A PH 22862A PH 34426 A PH34426 A PH 34426A PH 34426 A PH34426 A PH 34426A PH 22862 A PH22862 A PH 22862A
Authority
PH
Philippines
Prior art keywords
quinoline derivatives
novel quinoline
novel
derivatives
quinoline
Prior art date
Application number
PH34426A
Other languages
English (en)
Inventor
Jun-Ichi Matsumoto
Teruyuki Miyamoto
Hiroshi Egawa
Shinichi Nakamura
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of PH22862A publication Critical patent/PH22862A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH34426A 1985-10-29 1986-10-29 Novel quinoline derivatives and method of use thereof PH22862A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24225785 1985-10-29
JP28532385 1985-12-17
JP3262786 1986-02-17

Publications (1)

Publication Number Publication Date
PH22862A true PH22862A (en) 1989-01-19

Family

ID=27287785

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34426A PH22862A (en) 1985-10-29 1986-10-29 Novel quinoline derivatives and method of use thereof

Country Status (26)

Country Link
US (1) US4795751A (fr)
EP (2) EP0221463B1 (fr)
JP (2) JPS62277362A (fr)
KR (1) KR910006806B1 (fr)
CN (1) CN1009930B (fr)
AR (3) AR242031A1 (fr)
AT (2) ATE66210T1 (fr)
AU (1) AU594983B2 (fr)
CA (1) CA1340402C (fr)
DE (3) DE3680859D1 (fr)
DK (2) DK170593B1 (fr)
ES (2) ES2029786T3 (fr)
FI (1) FI87457C (fr)
GE (1) GEP19960467B (fr)
GR (1) GR3002475T3 (fr)
HU (1) HU200452B (fr)
IL (1) IL80404A (fr)
LU (2) LU88596I2 (fr)
MY (1) MY100574A (fr)
NL (2) NL970020I2 (fr)
NO (1) NO170726C (fr)
NZ (1) NZ218089A (fr)
PH (1) PH22862A (fr)
PT (1) PT83643B (fr)
SU (2) SU1635898A3 (fr)
YU (3) YU46414B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
EP0242789A3 (fr) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Dérivés de quinoléine et procédés pour leur préparation
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US5164392A (en) * 1987-10-16 1992-11-17 Dainippon Pharmaceutical Co., Ltd. Quinoline derivatives and antibacterial agent containing them
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
JP2709604B2 (ja) * 1988-06-29 1998-02-04 大日本製薬株式会社 マイコプラズマ汚染の防止または除去
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
FR2655545B1 (fr) 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
FR2681863B1 (fr) * 1991-09-27 1995-02-03 Rhone Dpc Europ Solution de sparfloxacine sa preparation et sel la constituant.
US5430028A (en) * 1992-05-26 1995-07-04 Ss Pharmaceutical Co., Ltd. 5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient
WO1993025545A1 (fr) * 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Nouveaux derives de quinoleine et procedes pour leur preparation
US5290794A (en) * 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
CN1038326C (zh) * 1993-07-20 1998-05-13 爱斯制药株式会社 5-氨基喹诺酮羧酸衍生物及其含有该衍生物作为活性成分的抗菌剂
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
AU757777B2 (en) 1998-12-04 2003-03-06 Influx, Inc. Inhibitors of multidrug transporters
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
CN1091103C (zh) * 1999-04-02 2002-09-18 中国科学院上海药物研究所 一类喹诺酮类化合物及它的制备和其用途
US6957105B2 (en) * 2002-03-26 2005-10-18 Cardiac Pacemakers, Inc. Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals
KR100519158B1 (ko) * 2002-12-21 2005-10-06 주식회사유한양행 퀴놀론 카르복실레이트 유도체의 제조방법
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20070196398A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone fatty acid salt compositions
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
EP3641747B1 (fr) 2017-06-22 2023-09-06 Cipla Limited Sécretagogues de par-4 destinées au traitement du cancer
CN110724097B (zh) * 2019-11-11 2021-03-09 山东畜牧兽医职业学院 一种治疗耐药性微生物菌的化合物及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753993A (en) * 1971-05-17 1973-08-21 Sterling Drug Inc 1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS58174367A (ja) 1982-04-07 1983-10-13 Tanabe Seiyaku Co Ltd キノリン誘導体及びその製法
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
DE3248506A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3306771A1 (de) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS60169475A (ja) * 1984-02-14 1985-09-02 Dai Ichi Seiyaku Co Ltd キノリン誘導体
DE3574380D1 (en) * 1984-02-17 1989-12-28 Daiichi Seiyaku Co 1,8-naphthyridine derivatives
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
ZA852369B (en) 1984-04-26 1985-12-24 Abbott Lab Quinoline antibacterial compounds
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS6110574A (ja) * 1984-06-25 1986-01-18 Hokuriku Seiyaku Co Ltd 6−フルオロ−1,4−ジヒドロ−4−オキソ−7−置換ピペラジニルキノリン−3−カルボン酸誘導体
IE58742B1 (en) 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPS6191183A (ja) * 1984-10-11 1986-05-09 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
EP0181521A1 (fr) * 1984-10-19 1986-05-21 Otsuka Pharmaceutical Co., Ltd. Composés d'acide 1-phényl substitué-4-oxo-3-quinoléine carboxylique
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones
EP0191185B1 (fr) * 1984-12-14 1990-03-07 Daiichi Seiyaku Co., Ltd. Dérivés de l'acide quinoléine-carboxylique
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
JPS6259263A (ja) * 1985-09-10 1987-03-14 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
EP0230053A3 (fr) * 1986-01-17 1988-03-30 American Cyanamid Company Acides 7-(substitué)pipérazinyl-1-éthyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoléine carboxyliques
EP0242789A3 (fr) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Dérivés de quinoléine et procédés pour leur préparation
GB8612137D0 (en) * 1986-05-19 1986-06-25 Fujisawa Pharmaceutical Co Quinolone compounds

Also Published As

Publication number Publication date
DE10075028I1 (de) 2000-12-14
LU90621I2 (fr) 2000-10-09
NL970020I2 (nl) 1998-01-05
LU88596I2 (fr) 1995-07-10
NL970020I1 (nl) 1997-08-01
CN86107491A (zh) 1987-04-29
KR910006806B1 (ko) 1991-09-02
DE3650018T2 (de) 1995-01-05
DK170774B1 (da) 1996-01-15
JPH0541633B2 (fr) 1993-06-24
NO170726C (no) 1992-11-25
MY100574A (en) 1990-12-15
AU6427786A (en) 1987-04-30
ES2029786T3 (es) 1992-10-01
DE3650018D1 (de) 1994-09-08
JPH0714918B2 (ja) 1995-02-22
CN1009930B (zh) 1990-10-10
FI87457B (fi) 1992-09-30
GR3002475T3 (en) 1992-12-30
AR243178A1 (es) 1993-07-30
KR870004019A (ko) 1987-05-06
HUT43839A (en) 1987-12-28
ATE66210T1 (de) 1991-08-15
NZ218089A (en) 1989-03-29
JPH0543551A (ja) 1993-02-23
FI87457C (fi) 1993-01-11
SU1635898A3 (ru) 1991-03-15
YU137291A (sh) 1994-01-20
AU594983B2 (en) 1990-03-22
YU137191A (sh) 1994-01-20
DK514586D0 (da) 1986-10-28
NO864247D0 (no) 1986-10-23
NL300014I2 (nl) 2001-02-01
NO170726B (no) 1992-08-17
DE10075028I2 (de) 2004-01-29
NO864247L (no) 1987-04-30
YU46414B (sh) 1993-10-20
AR242031A1 (es) 1993-02-26
DE3680859D1 (de) 1991-09-19
GEP19960467B (en) 1996-05-27
DK25992A (da) 1992-02-28
EP0375658A1 (fr) 1990-06-27
ATE109472T1 (de) 1994-08-15
ES2057197T3 (es) 1994-10-16
US4795751A (en) 1989-01-03
NL300014I1 (nl) 2000-10-02
SU1598873A3 (ru) 1990-10-07
IL80404A (en) 1990-06-10
DK514586A (da) 1987-04-30
YU183586A (en) 1988-04-30
PT83643B (pt) 1988-10-14
HU200452B (en) 1990-06-28
EP0221463A2 (fr) 1987-05-13
FI864299A0 (fi) 1986-10-23
DK25992D0 (da) 1992-02-28
FI864299A (fi) 1987-04-30
DK170593B1 (da) 1995-11-06
PT83643A (en) 1986-11-01
AR243520A1 (es) 1993-08-31
EP0221463B1 (fr) 1991-08-14
IL80404A0 (en) 1987-01-30
EP0375658B1 (fr) 1994-08-03
JPS62277362A (ja) 1987-12-02
EP0221463A3 (en) 1987-12-02
CA1340402C (fr) 1999-02-23

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