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PE20061125A1 - Composicion farmaceutica que comprende acetaminofen, cafeina y opcionalmente aspirina junto a un agente alcalino - Google Patents

Composicion farmaceutica que comprende acetaminofen, cafeina y opcionalmente aspirina junto a un agente alcalino

Info

Publication number
PE20061125A1
PE20061125A1 PE2005001253A PE2005001253A PE20061125A1 PE 20061125 A1 PE20061125 A1 PE 20061125A1 PE 2005001253 A PE2005001253 A PE 2005001253A PE 2005001253 A PE2005001253 A PE 2005001253A PE 20061125 A1 PE20061125 A1 PE 20061125A1
Authority
PE
Peru
Prior art keywords
caffeine
composition
alkaline agent
calcium carbonate
pharmaceutical composition
Prior art date
Application number
PE2005001253A
Other languages
English (en)
Inventor
Rong Liu
Michael Corbo
Gerard P Frunzi
Candice Y Choi
Atef Z Boulos
Rahul R Gandhi
Xiaohong Qi
Jatin Desai
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20061125A1 publication Critical patent/PE20061125A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION ANALGESICA/ANTIPIRETICA QUE CONTIENE UNA CANTIDAD EFECTIVA DE ACETAMINOFEN, CAFEINA Y OPCIONALMENTE ASPIRINA. SE REFIERE TAMBIEN A UN METODO QUE COMPRENDE LA INCORPORACION EN LA PRIMERA COMPOSICION DE UNA CANTIDAD ADECUADA DE UN AGENTE ALCALINO SELECCIONADO DE CARBONATO DE CALCIO, MEZCLA DE CARBONATO DE CALCIO E HIDROXIDO DE MAGNESIO, MEZCLA DE CARBONATO DE CALCIO, CARBONATO DE MAGNESIO Y OXIDO DE MAGNESIO Y PRODUCIR UNA SEGUNDA COMPOSICION BIOEQUIVALENTE A LA PRIMERA CON EL OBJETIVO DE ACELERAR LA ACTIVIDAD ANALGESICA/ANTIPIRETICA DE DICHA COMPOSICION. LA COMPOSICION PUEDE CONTENER 250mg DE ASPIRINA, 250 mg DE ACETAMINOFEN, 65mg DE CAFEINA, 43mg DE CARBONATO DE CALCIO, 75mg DE HIDROXIDO DE MAGNESIO, 5mg DE ACIDO CITRICO Y 5mg DE FOSFATO DE SODIO
PE2005001253A 2004-10-28 2005-10-26 Composicion farmaceutica que comprende acetaminofen, cafeina y opcionalmente aspirina junto a un agente alcalino PE20061125A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62281204P 2004-10-28 2004-10-28

Publications (1)

Publication Number Publication Date
PE20061125A1 true PE20061125A1 (es) 2006-11-08

Family

ID=35744599

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005001253A PE20061125A1 (es) 2004-10-28 2005-10-26 Composicion farmaceutica que comprende acetaminofen, cafeina y opcionalmente aspirina junto a un agente alcalino

Country Status (17)

Country Link
US (1) US20070298096A1 (es)
EP (1) EP1807068B1 (es)
JP (1) JP2008518914A (es)
CN (1) CN101048155A (es)
AR (1) AR051145A1 (es)
AT (1) ATE460930T1 (es)
AU (1) AU2005302618B2 (es)
BR (1) BRPI0520000A2 (es)
CA (1) CA2583517C (es)
DE (1) DE602005020048D1 (es)
MX (1) MX2007005121A (es)
NO (1) NO20072255L (es)
PE (1) PE20061125A1 (es)
PL (1) PL1807068T3 (es)
PT (1) PT1807068E (es)
RU (1) RU2398571C2 (es)
WO (1) WO2006049978A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0607085D0 (en) 2006-04-07 2006-05-17 Smithkline Beecham Corp Novel compositions
CN100417385C (zh) * 2006-09-26 2008-09-10 林星 一种用于治疗外伤的外用制剂
GB0707489D0 (en) * 2007-04-18 2007-05-23 Renaissance Pharma Compounds
CN101596163B (zh) * 2008-06-06 2012-06-27 康美保宁（四川）制药有限公司 阿咖酚微丸制剂及其制备方法
GB0813929D0 (en) * 2008-07-30 2008-09-03 Glaxo Group Ltd Novel method
CN102861040B (zh) * 2012-08-02 2014-04-23 广东环球制药有限公司 含有阿司匹林、对乙酰氨基酚和咖啡因的药物组合物及其制备方法
CN102949401A (zh) * 2012-09-06 2013-03-06 广东九明制药有限公司 对乙酰氨基酚、乙酰水杨酸和咖啡因组合物及其制备工艺
US10124005B1 (en) * 2017-12-15 2018-11-13 Lisa Josette Myslinski Multisymptom migraine combination medication
CN110711197B (zh) * 2018-07-12 2023-11-24 北京恒润泰生医药科技有限公司 阿司匹林和对乙酰氨基酚的分子复合物加咖啡因,其制备,活性及应用
CN108853124A (zh) * 2018-08-15 2018-11-23 康美保宁（四川）制药有限公司 一种阿咖酚制剂及其制剂方法
GB202007670D0 (en) * 2020-05-22 2020-07-08 Glaxosmithkline Consumer Healthcare Holdings Us Llc Pharmaceutical composition

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294819A (en) * 1980-08-18 1981-10-13 Bristol-Myers Company Alkaline analgesic capsule
CA1182049A (en) * 1981-07-13 1985-02-05 Francis J. Sterbenz Apap antacid composition
US5296241A (en) * 1991-04-03 1994-03-22 Brimberg Barnett J Therapeutic composition and method of using same for treatment of hangover
JP3122748B2 (ja) * 1991-11-29 2001-01-09 ライオン株式会社 イブプロフェン含有解熱鎮痛剤
JP3172749B2 (ja) * 1992-02-17 2001-06-04 ライオン株式会社 イブプロフェン含有製剤
JPH06227995A (ja) * 1993-02-03 1994-08-16 Takeda Chem Ind Ltd 安定化された固型製剤
JPH07206689A (ja) * 1994-01-21 1995-08-08 Barnett Lab Ltd 治療組成物および宿酔の治療のためのこの組成物の使用法
DE19502789A1 (de) * 1995-01-28 1996-08-01 Dirk Krischenowski Arzneimittel
GB9704524D0 (en) * 1997-03-05 1997-04-23 Smithkline Beecham Plc Composition
US5972916A (en) * 1997-07-14 1999-10-26 Bristol-Myers Squibb Company Compositions containing the nonprescription combination of acetaminophen, aspirin and caffeine to alleviate the pain and symptoms of migraine
JP2002012557A (ja) * 2000-06-28 2002-01-15 Lion Corp 内服薬組成物
JP4365107B2 (ja) * 2001-05-25 2009-11-18 エスエス製薬株式会社 医薬組成物
JP4553552B2 (ja) * 2003-01-08 2010-09-29 日東薬品工業株式会社 生体リズム応用キット

Also Published As

Publication number Publication date
ATE460930T1 (de) 2010-04-15
WO2006049978A1 (en) 2006-05-11
CA2583517A1 (en) 2006-05-11
BRPI0520000A2 (pt) 2009-04-07
MX2007005121A (es) 2007-06-22
CN101048155A (zh) 2007-10-03
US20070298096A1 (en) 2007-12-27
RU2007119641A (ru) 2008-12-10
CA2583517C (en) 2013-06-04
AR051145A1 (es) 2006-12-20
EP1807068B1 (en) 2010-03-17
EP1807068A1 (en) 2007-07-18
AU2005302618A1 (en) 2006-05-11
PT1807068E (pt) 2010-04-19
JP2008518914A (ja) 2008-06-05
NO20072255L (no) 2007-07-18
AU2005302618B2 (en) 2009-10-22
DE602005020048D1 (de) 2010-04-29
PL1807068T3 (pl) 2010-08-31
RU2398571C2 (ru) 2010-09-10

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