Nothing Special   »   [go: up one dir, main page]

JPS55162774A - Carbostyril derivative - Google Patents

Carbostyril derivative

Info

Publication number
JPS55162774A
JPS55162774A JP7143479A JP7143479A JPS55162774A JP S55162774 A JPS55162774 A JP S55162774A JP 7143479 A JP7143479 A JP 7143479A JP 7143479 A JP7143479 A JP 7143479A JP S55162774 A JPS55162774 A JP S55162774A
Authority
JP
Japan
Prior art keywords
formula
alkyl group
lower alkyl
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7143479A
Other languages
Japanese (ja)
Inventor
Kazuhisa Sakano
Takafumi Fujioka
Yasuo Oshiro
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP7143479A priority Critical patent/JPS55162774A/en
Publication of JPS55162774A publication Critical patent/JPS55162774A/en
Pending legal-status Critical Current

Links

Landscapes

  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A carbostyril derivative of formula I [R is H, formula II (R3 is H, OH, lower alkyl, lower alkanoyloxy group, etc.; R4 is H or alkyl group; R5 is cycloalkyl, lower alkanoyl group, etc.; l and m are 0 or 1W6, (l+m≤6); r is 2 or 3; x is halogen; n is 0, 1 or 2; R1 is H, lower alkyl group, etc.; R2 is H, lower alkyl group, formula II, etc.] or its acid addition salt.
EXAMPLE: 1-( 2-Propynyl )-7-[ 3-( 4-phenylpiperazinyl )propoxy ]-3,4-dihydrocarbstyril.
USE: A remedy or preventive for allergic diseases or a central nervous system depressant having an antihistamine action without side effects.
PROCESS: A compound of formula III (R2' is H, lower alkyl group, etc.; R6 is H, OH, etc.; X1 is halogen or mesityloxy group) is preacted with a compound of formula IV to give the compound of formula I (R is formula II; R3 is R6).
COPYRIGHT: (C)1980,JPO&Japio
JP7143479A 1979-06-06 1979-06-06 Carbostyril derivative Pending JPS55162774A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7143479A JPS55162774A (en) 1979-06-06 1979-06-06 Carbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7143479A JPS55162774A (en) 1979-06-06 1979-06-06 Carbostyril derivative

Publications (1)

Publication Number Publication Date
JPS55162774A true JPS55162774A (en) 1980-12-18

Family

ID=13460416

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7143479A Pending JPS55162774A (en) 1979-06-06 1979-06-06 Carbostyril derivative

Country Status (1)

Country Link
JP (1) JPS55162774A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04352723A (en) * 1991-05-31 1992-12-07 Otsuka Pharmaceut Co Ltd Akathisia therapeutic agent
WO1995011239A1 (en) * 1993-10-22 1995-04-27 Santen Pharmaceutical Co., Ltd. Novel phenoxyalkylpiperazine derivative
JP2011520815A (en) * 2008-05-09 2011-07-21 エモリー・ユニバーシテイ NMDA receptor antagonist for the treatment of neuropsychiatric disorders

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS552693A (en) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1*22dihydrooquinolinee22one derivative*its manufacture and allurgic affection therapeutic drug containing it
JPS55127371A (en) * 1980-02-14 1980-10-02 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS6332069A (en) * 1986-07-23 1988-02-10 新日本製鐵株式会社 Metal membrane lining roof structure
JPS63119467A (en) * 1987-10-21 1988-05-24 Otsuka Pharmaceut Co Ltd Carbostyryl derivative

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS552693A (en) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1*22dihydrooquinolinee22one derivative*its manufacture and allurgic affection therapeutic drug containing it
JPS55127371A (en) * 1980-02-14 1980-10-02 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS6332069A (en) * 1986-07-23 1988-02-10 新日本製鐵株式会社 Metal membrane lining roof structure
JPS63119467A (en) * 1987-10-21 1988-05-24 Otsuka Pharmaceut Co Ltd Carbostyryl derivative

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04352723A (en) * 1991-05-31 1992-12-07 Otsuka Pharmaceut Co Ltd Akathisia therapeutic agent
WO1995011239A1 (en) * 1993-10-22 1995-04-27 Santen Pharmaceutical Co., Ltd. Novel phenoxyalkylpiperazine derivative
JP2011520815A (en) * 2008-05-09 2011-07-21 エモリー・ユニバーシテイ NMDA receptor antagonist for the treatment of neuropsychiatric disorders

Similar Documents

Publication Publication Date Title
JO1351B1 (en) Chemical compounds
ES8707947A1 (en) Heterocyclic compounds, their production, and medicaments containing them.
PT81476A (en) Process for the preparation of quinolone carboxylic acid derivatives
ES2001341A6 (en) Novel guanidinomethylbenzoic acid derivatives.
ES8606330A1 (en) Quinolinecarboxylic acid derivatives and process for their preparation.
ES8704932A1 (en) Quinolonecarboxylic acid derivatives.
ES8207180A1 (en) Thienopyridinone derivatives, process for their preparation and their therapeutical use.
IL86080A (en) Substituted alkoxy-2-alkyl-indan and 1,2,3,4-tetrahydro-naphthol,process for the preparation thereof and pharmaceutical compositions comprising the same
ES8301200A1 (en) 1-Phenyl-2-cyclohexene-1-alkylamine derivatives, process for their preparation and medicines containing them.
JPS55162774A (en) Carbostyril derivative
JPS5655389A (en) Benzo ij quinolidine-2-carboxylic acid derivative, and its preparation
JPS55127371A (en) Carbostyril derivative
DE3464603D1 (en) 2-anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same
ES2001852A6 (en) Quinolonecarboxylic acid derivative and process for its preparation.
ES8401945A1 (en) Dibenzo(de,g)quinolines, processes for their preparation and pharmaceutical preparations containing them.
ES8106516A1 (en) Process for the preparation of halovincamone derivatives
IE56648B1 (en) Polyether compounds
YU43487B (en) Process for obtaining piperazine derivatives of theophyll
ES8207505A1 (en) Substituted phenoxy-aminopropanol derivatives, intermediates and processes for their production, and pharmaceutical preparations containing them.
JPS56142282A (en) Penem-3-carboxylic acid derivative and its preparation
ES8401062A1 (en) 1-Furyl-3,4-dihydroisoquinolines, process for their preparation, their use and medicines containing them.
EP0089635A3 (en) Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same
JPS5427573A (en) 3,4-dihydrocarbostyril derivatives
GB1388146A (en) Hydroxycrotonic acid derivatives
JPS57150686A (en) 1,3-diazepino(3,4,5-lm)-beta-carboline derivative and its preparation