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JPS54132218A - Separation of saponin constituents - Google Patents

Separation of saponin constituents

Info

Publication number
JPS54132218A
JPS54132218A JP3746478A JP3746478A JPS54132218A JP S54132218 A JPS54132218 A JP S54132218A JP 3746478 A JP3746478 A JP 3746478A JP 3746478 A JP3746478 A JP 3746478A JP S54132218 A JPS54132218 A JP S54132218A
Authority
JP
Japan
Prior art keywords
saponin
constituents
filler
separate
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3746478A
Other languages
Japanese (ja)
Inventor
Shun Matsushita
Tetsuo Ikushige
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Toyo Soda Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Soda Manufacturing Co Ltd filed Critical Toyo Soda Manufacturing Co Ltd
Priority to JP3746478A priority Critical patent/JPS54132218A/en
Publication of JPS54132218A publication Critical patent/JPS54132218A/en
Pending legal-status Critical Current

Links

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  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PURPOSE: To separate comstituents of saponin, rapidly, easily and reproducibly, by the liquid chromatography of a saponin-containing solution.
CONSTITUTION: A solution containing saponin constituents such as steroid saponin, triterpenoid saponin, etc., is passed through a chromatographic column packed with a filler (column temp., room temp W50°C; column pressure, 1W200 kg/cm2), and eluted with a non-aqueous solvent containing 4W40 V% of water to separate the saponin constituents and other co-existing components. The filler is a crosslinked polymer gel or a silica gel having C-OH structure at the surface, and having a compression strength of at least 200 kg/cm2, particle size of 5W177μ, and pore size of 13W105 Å.
COPYRIGHT: (C)1979,JPO&Japio
JP3746478A 1978-04-01 1978-04-01 Separation of saponin constituents Pending JPS54132218A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3746478A JPS54132218A (en) 1978-04-01 1978-04-01 Separation of saponin constituents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3746478A JPS54132218A (en) 1978-04-01 1978-04-01 Separation of saponin constituents

Publications (1)

Publication Number Publication Date
JPS54132218A true JPS54132218A (en) 1979-10-15

Family

ID=12498234

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3746478A Pending JPS54132218A (en) 1978-04-01 1978-04-01 Separation of saponin constituents

Country Status (1)

Country Link
JP (1) JPS54132218A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6136225A (en) * 1984-07-30 1986-02-20 Airin:Kk Method of isolating saponin
EP0251197A2 (en) * 1986-07-01 1988-01-07 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Triterpene saponins having anti-inflammatory, mucolytic and antiedemic activities, process for the preparation thereof and pharmaceutical compositions containing them
WO1988009336A1 (en) * 1987-05-29 1988-12-01 Cambridge Bioscience Corporation Saponin adjuvant
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CN105651925A (en) * 2016-04-15 2016-06-08 广西壮族自治区梧州食品药品检验所 Determination method of ginsenosides Rg1 and Re in ginseng leaves

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49124217A (en) * 1973-04-02 1974-11-28
JPS51149300A (en) * 1975-05-12 1976-12-22 Sanyo Kokusaku Pulp Co Ltd Process for purifying stevioside

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49124217A (en) * 1973-04-02 1974-11-28
JPS51149300A (en) * 1975-05-12 1976-12-22 Sanyo Kokusaku Pulp Co Ltd Process for purifying stevioside

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6136225A (en) * 1984-07-30 1986-02-20 Airin:Kk Method of isolating saponin
EP0251197A2 (en) * 1986-07-01 1988-01-07 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Triterpene saponins having anti-inflammatory, mucolytic and antiedemic activities, process for the preparation thereof and pharmaceutical compositions containing them
WO1988009336A1 (en) * 1987-05-29 1988-12-01 Cambridge Bioscience Corporation Saponin adjuvant
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CN105651925A (en) * 2016-04-15 2016-06-08 广西壮族自治区梧州食品药品检验所 Determination method of ginsenosides Rg1 and Re in ginseng leaves

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