JPH0224368A - Medicated printing ink - Google Patents

Abstract

PURPOSE:To obtain a medicated printing ink having a prolonged life of effectiveness in use and capable of effectively releasing most of the contained chemicals by adding a medicated thermoplastic powder to a printing ink. CONSTITUTION:The title ink contains a medicated thermoplastic powder. As the thermoplastic, an ethylene/vinyl acetate copolymer, an ethylene/(meth) acrylate copolymer or the like is desirable from the viewpoint of compatibilities with the chemicals. Examples of the chemicals include perfumes, rust preventives, mildewproofing agents, antiseptics and insect repellents. From the viewpoint of the printability of ink and the effectiveness of chemicals, etc., it is desirable that the mean particle diameter of the particles is in the range of 1mum-1mm. The density of the powder is important and is desirably in the range of 0.5-2.0g/cm<3>.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention is applicable to synthetic resin molded products, paper products, cloth products, leather products, wooden products such as wood or bamboo, ceramics, porcelain, glass products,
The present invention relates to a drug-containing printing ink that can be used on articles such as metals, indoor walls, etc., and has a long medicinal life.

[Prior Art] Conventionally, inks containing drugs have been inks containing drugs directly (such as Utility Model Application Publication No. 62-572), or formulations in which drugs are included in cyclodextrin (Utility Model Application Publication No. 62-572, etc.).
No. 1-102598, Utility Model Publication No. 61-103324, etc.)
, those in which the drug is adsorbed to a porous material, or those containing microcapsules containing the drug (Tokuko Kouko 5)
1-15769) etc.

[Problems to be Solved by the Invention] However, in these conventional methods, for example, those in which drugs are directly blended, the drug evaporates and volatilizes during printing, resulting in a short lifespan of drug efficacy, and in the method using cyclodextrin, Part of the drug remains clathrated and cannot exert its full medicinal effect. In addition, the adsorption method still has insufficient longevity of drug efficacy, and the microcapsule method has various problems in that the drug's efficacy is not exhibited unless the post-operation of destroying the microcapsules is involved.

The present invention has been made as a result of extensive studies to solve the above-mentioned problems. That is, an object of the present invention is to provide a printing ink that has a long lifespan in which the medicinal effect is expressed during use, allows most of the contained drug to be effectively released, and can exhibit the medicinal effect without any special post-operation. be.

[Means for Solving the Problems] The drug-containing printing ink of the present invention is characterized in that it contains powder and granules containing a drug-containing thermoplastic.

The thermoplastic plastic powder of the present invention includes petroleum resin, polybutene, polymethacrylic resin, polyvinyl chloride resin, polystyrene resin, unvulcanized natural rubber or synthetic rubber, carboxyl group-containing ethylene copolymer, high・Medium/low density ethylene homopolymer, polypropylene,
Homopolymers such as poly-1-butene and poly-4-methylpentene-1, ethylene, propylene, 1-butene, 1-
Polyolefin resins such as mutual copolymers of α-olefins such as hexene, and their modified products with unsaturated carboxylic acids or derivatives thereof, polyamide resins such as nylon-6, polyvinyl alcohol resins, polyester resins, ethylene- Examples include powdered saponified vinyl acetate copolymers and mixtures thereof.

Among these, carboxyl group-containing ethylene copolymers, particularly ethylene-vinyl acetate copolymers and ethylene-(meth)acrylic acid ester copolymers, are preferred in terms of their compatibility with drugs.

The drugs to be contained in the drug-containing plastic powder of the present invention include fragrances, rust preventives, antifungal agents, preservatives, insect repellents, rat repellents, deodorants, insecticides, repellents, and antifouling agents. It is.

Representative examples of the above drugs are listed below.

There are two types of fragrances: natural fragrances and artificial fragrances. Natural fragrances include animal fragrances such as jacora, civet, kasdol, and ambergris. There are vegetable fragrances made from special vegetable oils such as lavender oil, peppermint oil, lemon oil, orange oil, rose oil, camphor oil, sandalwood oil, and seed oil.

Artificial fragrances include synthetic fragrances made of terpene compounds or aromatic compounds, isolated fragrances whose components are separated from essential oils mainly through fractional distillation, and mixtures of various other isolated fragrances, synthetic fragrances, natural fragrances, etc. This includes blended fragrances that have been adjusted to be suitable for practical use.

As rust inhibitors, inorganic and organic acid salts of organic amines such as dicyclohexylammonium nitrite, cyclohexylammonium carbonate, isopropylammonium benzoate, diisopropylammonium succinate, etc., aromatic acids such as benzoic acid and naphtholic acid. Acid, carbon number 6-10 like caprylic acid, pelargonic acid, capric acid
fatty acids, heterocyclic amines such as benzotriazole, methylbenzotriazole, nitro-substituted aromatic compounds such as dinitrobenzene, nitronaphthalene, hexamethylenetetramine and its derivatives, etc.
One or a mixture of two or more of these may be used.

Specific examples of the other drugs mentioned above include food preservatives such as sorbic acid and dehydroacetic acid, thiabendazole, vinazine, and α-bromucinnamaldehyde (BC
Antifungal agents such as A), insect repellents such as DDT agents, BHC agents, drin agents, parathion agents, DDVP agents, PGP agents, etc., and sterilization of formalin, salicylic acid, taleosote, phenol, nitrofurazone, nitrofuryl acrylamide, etc. drug, naramycin (product name: Tanabe Seiyaku Co., Ltd.), ramtaline (product name: Matsushita Electric Works Co., Ltd.), cotomycin (product name:
(manufactured by Osaka Kasei Co., Ltd.), antifouling agents such as phenyl acetate water il, phenyl mercury oleate, copper naphthenate, copper oleate, and the like. You may use a mixture of more than one species.

As a method of incorporating drugs into plastic.

The plastic and drug may be melt-mixed in a customary kneading machine or extruder, but if the drug is a liquid such as a perfume, a plastic compatible with the drug may be impregnated by directly immersing it in the drug. be able to. Furthermore, in the case of a solid substance such as a rust preventive agent, a plastic compatible with the chemical agent can be impregnated by immersion in a solution in which the chemical agent is dissolved in a suitable solvent.

Further, in the present invention, the impregnation with the drug may be performed either before or after the plastic is pulverized.

As a method for pulverizing the plastic, any conventionally used appropriate method such as mechanical pulverization or solvent precipitation may be used. The average particle size of the powder or granules is suitably in the range of 1 μm to in+m from the viewpoint of the printability of the blended ink and the effect of the chemicals. If the particle size of the powder or granular material is less than 1 μm, the life of the drug's efficacy will be shortened and the cost will be high. On the other hand, the particle size of the powder is 1 mI!
If it exceeds 1, it is not preferable because there is a risk that the amount of the drug remaining without effective medicinal efficacy will increase.

In addition, the density of the powder is also important, and the density is 0.5 to 2.
It is preferably in the range of 0 g/cm3. When the density is outside this range, the stability of the ink deteriorates and phase separation occurs.

The printing ink of the present invention can contain, in addition to the drug-containing plastic powder, a natural resin or various synthetic resins in order to fix the powder to an object.

Furthermore, colorants (dyes, pigments, etc.) and other additives can be included as necessary.

These resins, colorants, compounding agents, etc. may be those used in ordinary printing inks.

For example, resins include thermoplastic resins, thermosetting resins,
Photocurable resins, IT& or two-component reactive resins, etc. can be used.

Coloring agents include organic coloring pigments, inorganic coloring pigments, dyes,
Metal powder, extender pigments such as calcium carbonate, barium carbonate, etc. can also be used.

Compounding agents include organic and inorganic foaming agents, plasticizers, stabilizers, antifoaming agents, slip agents such as wax or silicone, preservatives, antistatic agents, leveling agents, matting agents such as silica,
Examples include hollow powder and plastic particles.

The printing ink referred to herein refers to transparent ink or colored ink for printing solid prints or designs on a base material using printing machines such as offset, gravure, letterpress, flexo, and silk screen.

An example of the composition of the chemical-containing printing ink of the present invention is as follows.

Drug-containing thermoplastic plastic powder 5-60% by weight resin
5-40% by weight solvent or water
0-80% by weight Colorant O-40
Weight% Compounding agent: 0 to 15% by weight [Function] Since the printing ink of the present invention contains drug-containing plastic powder, the drug does not evaporate or transpire unnecessarily.

In addition, by appropriately selecting the plastic for powder and granules, the type of drug, and the particle size of the powder, the drug can be gradually leached and dispersed, so the effect of the drug can be adjusted uniformly and appropriately. The effect lasts for a long time until the end of the drug it contains.

[Example] The present invention will be explained in more detail below with reference to Examples.

(Example 1) A flavored gravure printing ink was produced by mixing and dispersing raw materials in the following formulation.

Color pigment 5% by weight Vinyl chloride/vinyl acetate copolymer resin 9% by weight Plasticity (dioctyl phthalate) 2% by weight Methyl ethyl ketone 17% by weight Methyl isobutyl ketone 10% by weight Toluene
Thermoplastic plastic powder containing 17% by weight of fragrance 40% by weight The above thermoplastic plastic powder containing fragrance is a powder of 400 mesh ethylene-vinyl acetate copolymer resin containing 50% by weight of a commercially available lemon-based blended fragrance. .

Gravure printing was performed on a vinyl chloride film using the gravure printing ink having the above formulation, but there were no problems with printability. When I left the printed matter indoors for three months,
The strength of the scent had weakened a little, but I could still feel the same scent as three months ago.

Immediately after printing, a protective coating of acrylic resin and two-component urethane resin was applied over the ink by gravure printing, and the persistence of the fragrance became even better.

(Example 2) A deodorant-containing gravure printing ink was produced by mixing and dispersing the raw materials in the following formulation.

Acrylic emulsion 59.4% by weight antifoaming agent
0.1% by weight anti-mold/preservative
0.5% by weight of deodorant-containing thermoplastic plastic powder 40.0% by weight The above deodorant-containing thermoplastic plastic powder contains deodorant (
Product name: Biodash, a 70 mesh pass ethylene-vinyl acetate copolymer resin powder containing 40% by weight of Osaka Soda (■) and (■ Tokyo Seikagaku Kenkyushin).

Solid printing was performed on nonwoven wallpaper using the above-mentioned gravure printing ink, but there were no problems with printability.

In addition, this wallpaper was pasted on the entire wall of an office reception room of about 20 m2, and the effect of deodorizing odors such as cigarette odors was tested, but it was found that at least 6.
Its effectiveness was recognized during the month of power.

(Example 3) A flexographic printing ink containing an insect repellent was manufactured by mixing and dispersing raw materials in the following formulation.

Water 32.0 parts by weight Ammonia (26% water) 1.0 parts by weight Plasticizer/stabilizer 1.0 parts by weight Antifoaming agent
o, i parts by weight Rosin-modified maleic acid resin (acid value 13-14') 11.0 parts by weight Acrylic emulsion (solid content 35%) 8.0 parts by weight Colored pigment 12.0 parts by weight Insect repellent-containing thermoplastic plastic powder 35.0 parts by weight The insect repellent-containing thermoplastic plastic powder contains an insect repellent (
Product name: Pinamin Forte (manufactured by Sumitomo Chemical) 3
It is a powder of 300 mesh bath of ethylene-vinyl acetate copolymer containing 0%.

Zahn Cup No. 1 is a flexo printing ink containing Okuki
When diluted with water for 15 seconds in step 3 and flexographically printed the entire surface or design on single-glaze bleached kraft paper, there was no problem with printability, and printing paper for bag making with good insect repellent effect could be obtained. Ta.

(Comparative Example 1) In Example 1, fragrance-containing thermoplastic plastic powder 4
A flavored gravure printing ink was produced using 20 parts by weight of a commercially available lemon-based mixed fragrance instead of 0 parts by weight.

Gravure printing was performed on vinyl chloride film using this ink, but it gave off a noticeable odor during drying during the printing process.
The scent of lemon filled the factory.

The scent of the obtained printed matter was weak, and almost no scent was detected after one week of being left indoors.

(Comparative Example 2) 40 parts by weight of commercially available lemon-based blended fragrance and 60 parts by weight of gelatin
50 parts by weight of the microcapsules containing gelatin were used in place of 40 parts by weight of the thermoplastic plastic powder containing fragrance in Example 1 to prepare microcapsules containing gelatin. Manufactured printing ink.

This printing ink was used to print on vinyl chloride film, but gravure printing was not possible due to the large particle size of the microcapsules, so printing was finally possible using silk screen printing.

The printed material had almost no scent, and when I rubbed it with my fingernail, I could barely smell it, but the scent didn't last for about a month.

(Comparative Example 3) In Comparative Example 2, 1 part by weight of a surfactant for swelling gelatin was added to a commercially available lemon-based blended fragrance to produce a flavored printing ink in the same manner.

Silk screen printing was performed on vinyl chloride film using this ink.

Although the printed matter emitted an odor without destroying the microcapsules, the odor was so weak that it could hardly be put to practical use.

(Comparative Example 4) In Comparative Example 2, cyclodextrin was used instead of gelatin to create a cyclodextrin-based clathrate of a commercially available lemon-based blended fragrance, and this cyclodextrin clathrate was used to create a fragrance-containing printing ink. Manufactured.

Because the particle size of cyclodextrin is large, silk screen printing is performed on the lid, but as the cyclodextrin is destroyed by heat, it emits a significant odor during the drying process of the printing process.
The scent of lemon filled the factory.

Immediately after printing, the scent was quite strong, but after 3 months, the scent almost disappeared.

[Effects of the Invention] As mentioned in L, since the printing ink of the present invention contains drug-containing plastic powder, there is no need for special post-operations such as breaking microcapsules as in the past. Instead, the stiffness itself exerts the effect of the drug. In addition, since the particle size of the powder and granules is appropriate, the drug contained therein is expressed until the end, and the aroma gradually leaches out, so the medicinal effect has a long lifespan. Moreover, the printing permeability of printing ink is also good.

Patent applicant: Japan Petrochemical Co., Ltd. Same as above Showa Ink Kogyo Co., Ltd.

Claims (6)

[Claims] (1) A drug-containing printing ink containing a drug-containing thermoplastic plastic powder. (2) The drug-containing printing ink according to claim 1, wherein the plastic is an ethylene copolymer having a carboxyl group or a mixture of one of them and another plastic. (3) The drug-containing agent according to claim (1) or claim (2), wherein the ethylene copolymer having a carboxyl group is an ethylene-vinyl acetate copolymer or an ethylene-(meth)acrylate copolymer. printing ink. (4) The drug is a fragrance, a rust preventive, a fungicide, a preservative, an insect repellent, a rat repellent, a deodorant, an insecticide, a repellent, and an antifouling agent, or a mixture thereof. Claim (1)
The drug-containing printing ink according to claim 3. (5) The drug-containing printing ink according to any one of claims (1) to (4), wherein the average particle diameter of the powder or granular material is in the range of 1 μm to 1 mm. (6) The drug-containing printing ink according to any one of claims (1) to (5), wherein the blending amount of the powder or granular material is in the range of 5 to 90% by weight.