JPH07213604A - Controller of blood sugar value - Google Patents

Abstract

PURPOSE:To provide a controller of a good sugar value which is reduced in size and simplified in operation so as to make it possible to make automatic blood sugar management over many sections in a hospital and is little in blood taking amt. and is safe. CONSTITUTION:This controller consists of an air pump 2 for taking blood and returning the blood from and to a first indwelling needle inserted into the body of a patient M, an insulin injector 4 for injecting insulin into the first indwelling needle 9, a glucose injector 5 for injecting glucose into a second indwelling needle 12 to be inserted into the body of the patient M, a glucose sensor 3 formed by disposing plural sensors for measuring the blood sugar value and a control means 6 for controlling the prescribed injection amt. of the insulin or glucose. The first indwelling needle 9, a glucose sensor 3 and a physiological salt bag 8 for a physiological salt soln. for periodic flushing of the first and second indwelling needles 9, 12 are communicated with each other by a blood taking tube 10, a sensor tube 15 and a chamber tube 16.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood sugar level control device. More specifically, the present invention relates to a blood sugar level control device capable of automatically and easily managing the blood sugar level of a diabetic patient or the like.

[0002]

2. Description of the Related Art For patients with unstable blood sugar levels, such as diabetic patients, treatments such as fasting, high calorie infusion, and insulin administration for blood sugar control during hospitalization or before, during, or after surgery. Is being performed as appropriate.

For example, as a conventional therapeutic device, blood is continuously collected by a pump from a needle inserted into a vein of a patient's arm, and heparin solution is put into it to prevent coagulation. Then, there is a device in which, after measuring a blood glucose level with a sensor, necessary insulin or glucose is administered into a patient's body by a pump according to a calculation by a computer.

Therefore, the apparatus is equipped with a dedicated pump for collection, injection of heparin solution, waste liquid after blood glucose level measurement, and a standard solution for calibrating and cleaning the electrodes of the blood glucose level measuring sensor.

[0005]

However, since the apparatus itself is heavy and tends to be large due to a large number of dedicated pumps and calibration liquids, the treatment of patients in a hospital requires internal medicine, surgery, ICU, CCU, etc. However, there is a problem that it is difficult to carry.

Further, there is a problem that the number of setting keys for calibration / washing is increased and it is difficult to operate the apparatus.

Further, since the device continuously measures the blood glucose level, there is a problem that the total amount of blood collected tends to increase.

In view of the above circumstances, the present invention provides a safe blood glucose level which is small in size and simple in operation so that blood glucose control can be automatically performed in multiple departments in a hospital, and a small amount of blood is collected. An object is to provide a control device.

[0009]

The blood glucose level control device of the present invention comprises: (a) an air pump for collecting blood from a first indwelling needle inserted into the body of a patient and returning it to the indwelling needle. ,
(B) an insulin injector for injecting insulin into the first indwelling needle; and (c) a second inserted into the patient's body.
A glucose injector for injecting glucose into the indwelling needle of
(D) A glucose sensor for measuring a blood glucose level contained in the blood, and (e) a required injecting amount of insulin or glucose is calculated according to the measured blood glucose level, and is administered to the patient's body based on the calculated value. And a glucose sensor, and a saline saline saline bag for flushing the first indwelling needle and the second indwelling needle. Is connected to tubes that communicate with each other, and the glucose sensor has a plurality of intermittently measurable sensors.

Further, the blood sugar level control device of the present invention is (a)
An air pump for collecting blood from a first indwelling needle that is inserted into a patient's body and returning blood to the indwelling needle; (b) an insulin injector for injecting insulin into the first indwelling needle; ) A glucose injector for injecting glucose into a second indwelling needle inserted into the body of a patient, and (d) a glucose sensor for measuring a blood glucose level contained in the blood,
(E) A control means for calculating a required injection amount of insulin or glucose according to the measured blood glucose level and controlling the injection amount to be administered to the patient's body based on the calculated value. A tube communicating with each other is connected to the indwelling needle, the glucose sensor, and a saline saline saline bag for regularly flushing the first indwelling needle and the second indwelling needle, and A pressure formed by a chamber connected to the saline bag and a constant volume container and a three-way solenoid valve arranged in parallel with the constant volume container between the chamber and the air pump. It is characterized in that a control mechanism is provided.

[0011]

Operation: The air pump is operated to inhale, and blood is collected from the first indwelling needle. The collected blood is sent to the tube on the glucose sensor side and then spotted on the sensor. The glucose sensor measures the blood glucose level contained in blood and transmits the measured blood glucose level to the control means. Further, the glucose sensor sets the next sensor at a predetermined position and moves it to the blood spotting part for the next measurement of the blood glucose level. In addition, you may move before a measurement.

The control means calculates the injecting amount of insulin or glucose according to the measured blood glucose level and operates the insulin injecting device or the glucose injecting device based on the calculated value to appropriately inject insulin or glucose to the patient. Control the administration.

Next, the air pump is exhausted to return the collected blood to the patient.

Then, physiological saline is periodically injected (flushing) into the patient's body from the first and second indwelling needles in order to prevent the coagulation of the invading and diffusing blood.

The blood collection and blood return are performed by operating an air pump by negative pressure and positive pressure in the chamber. When collecting blood, the maximum volume of blood is limited by the constant volume container of the pressure control mechanism to prevent excessive blood collection.

[0016]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The blood sugar level control device of the present invention will be described below with reference to the accompanying drawings.

FIG. 1 is a perspective view showing an embodiment of the blood sugar level control device of the present invention, FIG. 2 is an explanatory view showing the glucose sensor in FIG. 1, and FIG. 3 is an explanatory view showing the pressure control mechanism in FIG. is there.

As shown in FIG. 1, a blood glucose level control device 1 of the present invention includes an air pump 2 for collecting blood from a patient M and returning it to the patient M, and a glucose sensor 3 for measuring the blood glucose level. And a control means 6 for calculating an injection amount of insulin or glucose from the blood glucose level and controlling a required injection amount to be administered into the body from the insulin injector 4 or the glucose injector 5 based on the calculated value. .

The blood glucose control device 1 is fixed to a movable stand 7. A saline bag 8 containing physiological saline is suspended above the stand 7.

A blood collecting tube 10 and an insulin injecting tube 11 drawn out from the insulin injecting device 4 are connected to the first indwelling needle 9 inserted into the arm of the patient M. Further, to the second indwelling needle 12 inserted into the arm of the patient M, a glucose injection tube 13 from the glucose injector 5 and a saline tube 14 inserted into the saline bag 8 are connected.

The blood collection tube 10 has a sensor tube 15 whose one end extends into the glucose sensor 3.
And a chamber tube 16 to be inserted into the raw food bag 8.

The tip of the sensor tube 15 is inserted into the waste liquid bag 17.

On the other hand, the chamber tube 16 has a chamber 18 formed in the middle thereof, and the air pump 2 is connected to the chamber 18 via a pressure control mechanism 19 and an air filter 20.

Blood collection tube 10 and saline tube 1
4, sensor tube 15 and chamber tube 1
6, solenoid valves (hereinafter, simply referred to as valves) 21, 22, 23, and 24 are connected to each other.

The inner diameters of the blood collection tube 10, the sensor tube 15, and the chamber tube 16 are not particularly limited in the present invention, but are approximately 0.1 to 3.0 mm and 0.1 to 1.5 mm, respectively. , 0.5 ~
5.0 mm is a standard.

The glucose sensor 3 is housed in a sensor box 25 as shown in FIGS.
A rotatable disk 27 in the case 26, and a plurality of disposable sensors 2 arranged on the disk 27 at equal intervals in the circumferential direction.
8 and. Further, a notch 31 is formed in the case 26 so that the electrode 29 of the sensor 28 can face the blood spotting part 30 provided in the sensor tube 15.

As the sensor 28, an enzyme electrode type glucose sensor (for example, G2 electrode manufactured by A & D Co., Ltd.), an oxygen electrode type glucose sensor, a hydrogen peroxide electrode type glucose sensor or the like is used.

As shown in FIG. 3, the pressure control mechanism 19 includes a constant volume container 32 and three-way solenoid valves (hereinafter simply referred to as solenoid valves) 33, 3 arranged in parallel with the constant volume container 32.
4 and.

The upper part of the constant volume container 32 communicates with an intake passage 35 and an exhaust passage 36 of the air pump 2. The intake passage 35 and the exhaust passage 36 are provided with the solenoid valves 33 and 34, respectively. It is connected. The lower part of the constant volume container 32 communicates with the air filter 20. Further, the constant volume container 32 has an inner balloon portion 37 capable of expanding and contracting inside thereof connected to the lower tube. In addition, the arrow in a figure shows the flow of air.

The control means 6 calculates the injection amount of insulin and glucose, and the insulin injector 4 based on the calculation value calculated by the calculation circuit.
And a control circuit for controlling the required injection amount of insulin or glucose from the glucose injector 5, and the intake / exhaust switching of the air pump 2 and the valves 21, 22, 23, 24.
And a switching circuit that controls switching between opening and closing of the solenoid valves 33 and 34.

Reference numeral 38 is a touch operation display, and 39 is a printer.

Although the glucose injector 5 is externally attached in FIG. 1, it may be incorporated in the control device 1 itself.

Next, the operation of the blood sugar level control device of the present invention will be described.

First, the valve 2 is turned on when the power is turned on.
1, 22, 23 and 24 are opened (hereinafter simply referred to as ON). Next, a circuit (flow path) such as a saline tube is set in the valves 21, 22, 23 and 24. After confirming the set, press the confirmation key on the touch operation display 38
The valves 21, 22, 23, and 24 are closed (hereinafter, simply O
FF). A solenoid valve 34 is turned on, the air pump 2 is operated, and a leak test is performed in order to confirm the connection state to the circuit around the chamber 18 and the valve. After the leak test is completed, the operation of the air pump 2 is stopped. Here, the program set values such as the insulin injection amount in the control means 6 are confirmed. After that, the chamber tube 16 and the saline tube 14
Puncture the raw food bag 8. Turn on the valve 24.
Then, the valve 23 is turned on for a certain period of time, and if physiological saline flows from the chamber tube 16 to the sensor tube 15 and seeps into the waste bag 17, the valve 2
Close 3.

Next, the valve 21 is turned on, and if physiological saline flows toward the blood collection tube 10 side and seeps out from the first indwelling needle 9, the valve 21 is turned off.

As described above, the blood collection tube 10, the sensor tube 15 and the chamber tube 16 are washed with physiological saline and filled with physiological saline.

Next, the valve 22 is turned on, and when physiological saline oozes out from the second indwelling needle 12 after a certain time, the valve 22 is turned off. As a result, the saline tube 14 is washed with physiological saline and filled with physiological saline.

Next, the insulin injector 4 is actuated, and when insulin is filled in the insulin infusion tube 11 after a fixed time, the insulin injector 4 is stopped by the stop key. Similarly, when the glucose injection tube 5 is operated to fill the glucose injection tube 13 with glucose after a predetermined time, the glucose injection tube 5 is stopped by the stop key.

When connecting to the indwelling needle after priming, when it is desired to fill the end of the blood collection tube 10 or the saline tube 14 with physiological saline up to the end,
There is a case where it is necessary to additionally inject the physiological saline into the blood collection tube 10 or the saline tube 14. In this case, the operation of adding the required amount by setting the key on the touch operation display 37 is performed by turning the valve 22 from ON to OFF by the stop key or by turning the valve 21 from ON to OFF by the stop key. You can After that, the injection amount of insulin and glucose was set to 0.
Set.

With the above, initial preparations for managing the blood sugar level are completed.

Next, the operation of administering insulin and glucose will be described.

First, the arm of the patient M is punctured with the first indwelling needle 9 and the second indwelling needle 12.

For blood collection, the air pump 2 is operated to turn on the solenoid valve 33 and turn on the solenoid valve 34.
It is set to FF, and the solenoid valve 33 is turned off after a fixed time. As a result, negative pressure is generated in the chamber 18, and then the valve 21 is turned on to collect blood in the blood collection tube 10. The amount of blood collected at this time is
It depends on the volume of the inner balloon portion 37 of the constant volume container 32. First, the air in the inner balloon portion 37 is completely deflated before the start of blood collection. Next, a negative pressure is applied to the constant volume container 32 by the air pump 2, and a negative pressure is also generated in the inner balloon portion 37. Since this negative pressure component is directly applied to the line of the blood collection tube 10, it becomes a blood collection suction pressure. Here, the inner balloon part 3
Since the volume of 7 is fixed, the volume of the constant volume container 32 can be taken out of the body at the maximum.

The amount of blood collected can be controlled by turning off the valve 21 before taking out the blood corresponding to the volume. It should be noted that blood is turned on through the valves 21 and 23.
By setting to N, the blood pressure alone can be taken out from the body, so the blood pressure can also be used together.

After blood collection is completed, the solenoid valve 34 is turned on.
Then, the negative pressure in the chamber 18 is released.

Next, by turning on the valve 23, the blood sampled is sent to the sensor tube 15 side by the blood pressure of the patient M. Blood is the blood spot 30
When the glucose sensor 3 is delivered to the front (see FIG. 2).
Then, the electrode 29 of the new sensor 28 moves and is positioned at the blood spotting part 30. When the blood is spotted, blood glucose measurement is started, the glucose sensor 3 is moved to the original position (direction B in FIG. 2), and is separated from the blood spotting part 30.

After the measurement is completed, the blood glucose measurement value is transmitted to the control means 6 of the control device 1 and calculated into a predetermined insulin or glucose infusion amount that must be administered to the patient M according to the blood glucose level. At this time, the injection rate is also determined.

Then, the control means 6 operates the insulin injector 4 or the glucose injector 5 to start administration of insulin or glucose to the patient M.

When the control means 6 receives a blood glucose level signal from the glucose sensor 3, it turns on the valve 24 and turns off the valve 21 after a certain period of time.
A signal is issued to turn on the valve 23. As a result, the saline solution flows from the chamber tube 16 to the sensor tube 15 due to its head pressure (gravity). As a result, the blood in the sensor tube 15 will be collected in the waste bag 1.
7, the sensor tube 15 can be washed. After cleaning, the valves 23 and 24 are turned off.

Next, the solenoid valve 33 is turned off and the solenoid valve 34 is turned on to make the inside of the chamber 18 have a positive pressure by the action of the air pump 2. And the valve 21
When turned on, the positive pressure causes chamber tube 16
The physiological saline inside is pushed out, and the blood in the blood collection tube 10 is returned to the body of the patient M. At the same time, it also serves to wash the blood collection tube 10. In addition, chamber 1
For the positive pressure in 8, the drop pressure of physiological saline can be used by opening the valve 24.

Further, by providing a valve below the chamber 18, it is possible to prevent blood from going to the chamber 18, so that there is no fear of residual blood remaining in the chamber 18 when returning blood, and in turn a return is made in a short time. Blood can be generated, and blood collection and blood return can be performed more smoothly.

The above blood collection, insulin and glucose administration, and blood return operations are periodically performed within a set time.

Further, in this embodiment, the flushing of the first indwelling needle 9 and the second indwelling needle 12 is regularly performed.

Flushing is physiological saline in order to prevent blood from invading the first and second indwelling needles 9 and 12 and their connecting tubes, which are connection sites with the body, and coagulating due to blood pressure and diffusion. Water for the first and second indwelling needles 9,
It is an operation of injecting into 12 and returning blood into the body.

When flushing the first indwelling needle 9, the valve 24 and the valve 21 are turned on. That is, the physiological saline solution is pushed out of the saline bag 8 by the head pressure to push the physiological saline solution in the blood collection tube 10 to return the blood diffused in the first indwelling needle 9 to the body. When the drop pressure of the physiological saline is insufficient (for example, when there is not much difference between the position of the saline back 8 and the patient's heart position or the patient's blood pressure is high), the air pump 2 is operated. May be. Generally, it need not be activated.

When flushing the second indwelling needle 12, the valve 22 is turned on. That is, similarly to the above, the physiological saline in the saline tube 14 is pushed out by the head pressure of the physiological saline to return the blood in the second indwelling needle 12 to the body.

When flushing is completed, the valve 2
Turn off 1, 22, 24.

[0058]

As described above, according to the present invention, it is possible to eliminate the need for calibration and maintenance such as cleaning before use of each sensor, after use of calibration, and storage when the device is stopped. It is not necessary to equip a liquid or a dedicated pump, and there is no need to perform calibration setting, key input, etc., and the device can be made compact and easy to operate.

Further, except for the blood volume necessary for measuring the blood glucose level, almost all the blood is returned to the body of the patient, so that the total amount of blood collected can be made as small as possible and the burden on the patient can be reduced. Furthermore, since it is not necessary to equip a dedicated pump for injecting the heparin solution for coagulation, further miniaturization can be achieved.

The blood is returned with physiological saline, and the blood collection tube and the like are filled with physiological saline except during blood collection. Therefore, for blood that may gradually enter the blood collection tube etc. from the indwelling needle that is the connection part to the body, flush the blood out with regular saline solution to periodically release the blood outside the body. Since the time during which the foreign matter is in contact with the foreign object can be shortened as much as possible, blood coagulation can be suppressed as much as possible.

Further, since a tubing pump or the like is not used for blood collection, pressure is generated in the constant volume container and blood is collected up to that volume at the maximum, thus preventing excessive blood collection due to malfunction due to an accident. be able to.

[Brief description of drawings]

FIG. 1 is a perspective view showing an embodiment of a blood sugar level control device of the present invention.

FIG. 2 is an explanatory view showing the glucose sensor in FIG.

FIG. 3 is an explanatory diagram showing a pressure control mechanism in FIG.

[Explanation of symbols]

 1 Control Device 2 Air Pump 3 Glucose Sensor 4 Insulin Injector 5 Glucose Injector 6 Control Means 8 Raw Food Bag 9 First Indwelling Needle 10 Blood Collection Tube 11 Insulin Infusion Tube 12 Second Indwelling Needle 13 Glucose Infusion Tube 14 Raw Food Tube 15 Sensor tube 16 Chamber tube 18 Chamber 19 Pressure control mechanism 28 Sensor 32 Constant volume container 33, 34 Solenoid valve

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Yuzo Nozoe 3-23-14 Higashiikebukuro, Toshima-ku, Tokyo Within A & D Co., Ltd. (72) Inventor Susumu Kobayashi 3-chome, Honjo-nishi, Kita-ku, Osaka No. 3 Stock Company Nissho

Claims (2)

[Claims] 1. An air pump for (a) collecting blood from a first indwelling needle that is inserted into a patient's body and returning blood to the indwelling needle, and (b) injecting insulin into the first indwelling needle. An insulin injector, (c) a glucose injector for injecting glucose into a second indwelling needle inserted into the patient's body, (d) a glucose sensor for measuring a blood glucose level contained in the blood, and (e) ) Calculate the required infusion of insulin or glucose according to the measured blood glucose level,
Control means for controlling the injection amount to be administered to the body of the patient based on the calculated value, the first indwelling needle,
Tubes communicating with each other are connected to the glucose sensor and a saline saline bag for regularly flushing the first indwelling needle and the second indwelling needle, and the glucose sensor is A blood sugar level control device comprising a plurality of sensors that can be measured intermittently. 2. (a) An air pump for collecting blood from a first indwelling needle that is inserted into a patient's body and returning blood to the indwelling needle; and (b) injecting insulin into the first indwelling needle. An insulin injector, (c) a glucose injector for injecting glucose into a second indwelling needle inserted into the patient's body, (d) a glucose sensor for measuring a blood glucose level contained in the blood, and (e) ) Calculate the required infusion of insulin or glucose according to the measured blood glucose level,
Control means for controlling the injection amount to be administered to the body of the patient based on the calculated value, the first indwelling needle,
Tubes communicating with each other are connected to the glucose sensor and a saline saline saline bag for regularly flushing the first indwelling needle and the second indwelling needle, and the saline bag is connected to the saline bag. A chamber is formed in the communicating tube, and a pressure control mechanism including a constant volume container and a three-way solenoid valve arranged in parallel with the constant volume container is provided between the chamber and the air pump. A blood sugar level control device characterized by the following.