JP5845018B2 - Laminate for packaging - Google Patents

Description

  The present invention relates to a packaging laminate for packaging, for example, pharmaceuticals, foods, cosmetics and the like.

  Conventionally, as a packaging laminate used for packaging pharmaceuticals, foods, cosmetics, and the like, various products obtained by laminating synthetic resin films and sheets have been proposed (see, for example, Patent Documents 1 to 3).

Patent Document 1 includes a base material and a polyethylene layer and an ethylene-vinyl acetate copolymer layer which are sequentially laminated on both surfaces of the base material as a pharmaceutical packaging material used for an infusion bag or the like. Is disclosed.
Patent Document 2 discloses a laminate composed of a base material layer, an intermediate layer, and an inner surface layer, wherein the intermediate layer is a plastic film and the inner surface layer is composed of three thermoplastic resin layers. It is disclosed.
Furthermore, Patent Document 3 discloses a multilayer hollow container having an outermost layer, a burr recovery layer, an adhesive layer, a barrier layer, and an innermost layer.

Japanese Patent No. 2960519 Japanese Patent No. 4139489 JP 2007-152712 A

By the way, in the above packaging materials, in particular, the problem of residual solvent has become particularly prominent. In addition, the odor due to the residual solvent and the deterioration and contamination of the contents due to the residual solvent are also problematic.
However, the technique described in Patent Document 1 does not assume adaptation to a residual solvent, and the deterioration of contents due to the residual solvent cannot be avoided.

Moreover, the technique described in Patent Document 2 is for preventing permeation of volatile components such as alcohol in the contents, and cannot be applied to the residual solvent.
Furthermore, the technique described in Patent Document 3 is a multilayer hollow container using a low-elution polyolefin resin with a small amount of metal elution, and cannot be applied to a residual solvent as in the techniques described in Patent Documents 1 and 2.

  The present invention has been made in view of such problems, and in particular, when used in an infusion bag or the like, it is intended to provide a packaging laminate capable of preventing contamination of contents from residual solvent. Objective.

In order to solve the above problems, the present invention proposes the following means.
That is, the packaging laminate according to the present invention is a packaging laminate having a base material layer and a sealant layer that are laminated to each other, and the sealant layer is a linear low density in an ethylene-vinyl alcohol copolymer resin. It is characterized by being laminated with polyethylene.

  According to the packaging laminate having such characteristics, since the sealant layer is formed by laminating the ethylene-vinyl alcohol copolymer resin and the linear low density polyethylene, the sealant layer can be made a barrier. .

Moreover, in the laminated body for packaging which concerns on this invention, it is preferable that the said linear low density polyethylene is laminated | stacked so that the said ethylene-vinyl alcohol copolymer resin may be inserted | pinched.
Thereby, the elution of the residual solvent can be prevented more reliably.

Furthermore, in the packaging laminate according to the present invention, the base material layer preferably contains aluminum.
When the base material layer contains aluminum, the base material layer can be made a barrier. Thus, barrier properties can be imparted to the entire layers of the packaging laminate, and elution of the residual solvent can be more reliably prevented.

Moreover, in the laminated body for packaging which concerns on this invention, it is preferable that the said base material layer is a barrier film which has gas barrier property.
Also by this, barrier properties can be imparted to the entire layers of the packaging laminate, and the elution of the residual solvent can be more reliably prevented.

Furthermore, the packaging laminate according to the present invention preferably has an intermediate layer containing aluminum between the base material layer and the sealant layer.
Thereby, an intermediate | middle layer exhibits barrier property and the elution of a residual solvent can be prevented more reliably as the whole laminated body for packaging.

Moreover, it is preferable that the laminated body for packaging which concerns on this invention permeate | transmits light in the lamination direction.
Thereby, the contents can be visually recognized from the outside of the packaging laminate.

  According to the packaging laminate of the present invention, since the sealant layer is formed by laminating the ethylene-vinyl alcohol copolymer resin and the linear low density polyethylene, the sealant layer can be made a barrier. Thereby, it becomes possible to avoid that the residual solvent contained, for example in printing ink, an adhesive agent, etc. elutes in the content.

It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on 1st embodiment and Example 1, 2 of this invention. It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on 2nd embodiment and Examples 3 and 4 of this invention. It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on 3rd embodiment and Example 5, 6 and 7 of this invention. It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on the comparative examples 1 and 2. FIG. It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on the comparative examples 3 and 4. FIG. It is a longitudinal cross-sectional view of the laminated body for packaging which concerns on the comparative examples 5, 6, and 7. FIG.

Hereinafter, 1st embodiment of the laminated body for packaging of this invention is described in detail with reference to FIG.
As shown in FIG. 1, the laminated body 100 for packaging is used as a packaging material in, for example, a medical infusion bag or a secondary outer bag filled with a plurality of medicines such as an infusion bag. The layer 10, the adhesive layer 20, and the sealant layer 30 are sequentially laminated.

  As the base material layer 10, for example, a material containing aluminum such as an aluminum foil having a thickness of 7 μm or an aluminum-deposited PET film having a thickness of 12 μm is used. When the base material layer 10 contains aluminum, the barrier property of the base material layer 10 can be ensured.

  The adhesive layer 20 is interposed between the base material layer 10 and the sealant layer 30 in order to firmly laminate the base material layer 10 and the sealant layer 30. As the adhesive layer 20, for example, an organic solvent-type adhesive, particularly an ester adhesive can be used. By applying dry lamination using such an adhesive layer 20, the base material layer 10 and the sealant layer 30 are laminated and integrated.

The sealant layer 30 is laminated with the base material layer 10 via the adhesive layer 20, and has a three-layer structure in this embodiment. The sealant layer 30 has a structure in which sheets of a linear low density polyethylene 31, an ethylene-vinyl alcohol copolymer resin 32, and a linear low density polyethylene 31 are laminated in order from the base material layer 10 side. The thickness of the sealant layer 30 as a whole is set to about 60 μm, for example.
That is, the sealant layer 30 has a structure in which a pair of sheets of linear low-density polyethylene 31 are laminated so as to sandwich a sheet of ethylene-vinyl alcohol copolymer resin 32. In addition, since the linear low density polyethylene 31 is a polyolefin resin, it has excellent heat sealability.

According to such a packaging laminate 100, the sealant layer 30 is formed by laminating the ethylene-vinyl alcohol copolymer resin 32 and the linear low-density polyethylene 31 to each other, so that the sealant layer 30 is made a barrier. be able to.
In particular, since the sealant layer 30 of the present embodiment is a pair of linear low-density polyethylene 31 so as to sandwich the ethylene-vinyl alcohol copolymer resin 32, the sealant layer 30 can be made more reliable as a barrier. Can be planned. Thereby, for example, the elution of the residual solvent contained in the adhesive layer 20 can be reliably prevented.

  Furthermore, in this embodiment, the base material layer 10 can also be made to be a barrier by containing aluminum. Thereby, barrier properties can be imparted to the entire layers of the packaging laminate 100, and the elution of the residual solvent can be more reliably prevented.

Next, a second embodiment of the present invention will be described in detail with reference to FIG. In the second embodiment, the same components as those in the first embodiment are denoted by the same reference numerals, and detailed description thereof is omitted.
As shown in FIG. 2, the laminated body 100 for packaging of this embodiment is comprised by laminating | stacking the base material layer 10, the ink layer 40, the contact bonding layer 20, the intermediate | middle layer 50, the contact bonding layer 20, and the sealant layer 30 one by one. Has been.

  As the base material layer 10, an inorganic compound vapor-deposited PET film is used. For example, an aluminum vapor-deposited PET film having a thickness of 12 μm is preferably used.

  The ink layer 40 is a layer formed by applying a pattern ink to the surface of the base material layer 10 on the side of the sealant layer 30 by, for example, gravure printing.

As the intermediate layer 50, for example, a sheet containing aluminum such as an aluminum foil having a thickness of 7 μm or an aluminum-deposited PET film having a thickness of 12 μm can be used. The intermediate layer 50 is laminated and integrated with the base material layer 10 coated with the ink layer 40 as described above by performing dry lamination using the adhesive layer 20.
A sealant layer 30 similar to that of the first embodiment is laminated on the surface of the intermediate layer 50 opposite to the base material layer 10 by dry lamination using the adhesive layer 20.

  Also in such a laminated body 100 for packaging, a pair of linear low density polyethylene 31 is laminated so as to sandwich the ethylene-vinyl alcohol copolymer resin 32 as in the first embodiment. A barrier can be more reliably achieved. Thereby, for example, the elution of the residual solvent contained in the adhesive layer 20 and the ink layer 40 can be reliably prevented.

  Furthermore, in addition to the formation of a barrier of the base material layer 10 due to the base material layer 10 containing aluminum, the intermediate layer 50 containing aluminum is interposed between the base material layer 10 and the sealant layer 30. When the intermediate layer 50 exhibits the barrier properties, the elution of the residual solvent can be prevented more reliably as the entire laminate 100 for packaging.

Next, a third embodiment of the present invention will be described in detail with reference to FIG. In the third embodiment, the same components as those in the first embodiment and the second embodiment are denoted by the same reference numerals, and detailed description thereof is omitted.
As shown in FIG. 3, the packaging laminate 100 of the present embodiment is configured by sequentially laminating a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30. In the present embodiment, the base material layer 10, the ink layer 40, the adhesive layer 20, and the sealant layer 30 each have light transmittance.

As the base material layer 10, for example, an inorganic compound vapor-deposited PET film is used. For example, an aluminum vapor-deposited PET film having a thickness of 12 μm is preferably used.
Moreover, as this base material layer 10, the barrier film which has gas barrier property, for example can also be used. As this barrier film, for example, a barrier OPP film having a thickness of 30 μm and a barrier Ny film having a thickness of 15 μm formed by biaxial stretching can be used. Thereby, the barrier property of the base material layer 10 can be reliably ensured.

The barrier OPP film has a configuration in which a pair of polypropylenes are laminated so as to sandwich an ethylene-vinyl alcohol copolymer resin, for example.
The barrier Ny film has a structure in which a pair of nylons are laminated so as to sandwich an ethylene-vinyl alcohol copolymer resin.

On the surface of the base material layer 10 on the side of the sealant layer 30, an ink layer 40 made of a pattern ink applied by, for example, gravure printing or the like is formed.
And the sealant layer 30 similar to 1st embodiment and 2nd embodiment is given to the surface on the opposite side to the base material layer 10 in the ink layer 40 by giving the dry lamination by the adhesive agent as the contact bonding layer 20. Are stacked.

  In such a packaging laminate 100, as in the first embodiment and the second embodiment, a pair of linear low density polyethylenes 31 are laminated so as to sandwich the ethylene-vinyl alcohol copolymer resin 32 therebetween. In addition, the barrier layer of the sealant layer 30 can be more reliably achieved. Thereby, for example, the elution of the residual solvent contained in the adhesive layer 20 and the ink layer 40 can be reliably prevented.

  Furthermore, since the base material layer 10, the ink layer 40, the adhesive layer 20, and the sealant layer 30 each have light transmittance, when the content is packaged with the packaging laminate 100, the content is externally received. It can be visually recognized. This makes it possible to provide a packaging material that is easy to use.

As described above, according to the packaging laminate 100 of each of the embodiments described above, the contents are protected from the residual solvent that is often contained in the adhesive for dry lamination that is frequently used in printing inks and packaging materials. For this reason, by forming all the layers of the base material layer 10 that contacts the ink and the layer that is in contact with the ink and the adhesive as barriers, it is possible to suppress the dissolution of the residual solvent and protect the contents.
As the base material layer 10 and the intermediate layer 50, in addition to the above configuration, a plastic film provided with a vapor deposition layer of a metal such as aluminum or iron or an inorganic compound such as aluminum oxide or silicon oxide, polyethylene, polypropylene A coextruded film of polyamide and polyvinyl alcohol, a laminated film, an MXD nylon film, or the like can be used.

  As mentioned above, although embodiment of this invention was described in detail, unless it deviates from the technical idea of this embodiment, it is not limited to these, A some design change etc. are possible.

For example, in the embodiment, the sealant layer 30 has a three-layer structure in which a linear low-density polyethylene 31, an ethylene-vinyl alcohol copolymer resin 32, and a linear low-density polyethylene 31 are sequentially laminated. For example, the sealant layer 30 may have a two-layer structure of a linear low-density polyethylene 31 and an ethylene-vinyl alcohol copolymer resin 32. Also by this, the elution of a residual solvent can be prevented.
Further, in the first and second embodiments, by appropriately selecting the material of each layer, each layer may be light transmissive so that the contents can be visually recognized.

Hereinafter, the effect of the laminated body for packaging of the present invention will be described based on specific examples.
First, the laminated body for packaging (Examples 1 to 7) 100 corresponding to the embodiment and the laminated body for packaging (Comparative Examples 1 to 7) 110 to be compared were prepared. In each of the examples, the sealant layer 30 has a three-layer structure of a linear low density polyethylene 31, an ethylene-vinyl alcohol copolymer resin 32, and a linear low density polyethylene 31, whereas in the comparative example, the sealant layer Reference numeral 30 denotes a single-layer structure of only the linear low-density polyethylene 31.

(Example 1)
As shown in FIG. 1 in the first embodiment, a packaging laminate 100 including a base material layer 10, an adhesive layer 20, and a sealant layer 30 was prepared as Example 1.
Specifically, an aluminum foil (Sumi Light Aluminum Foil Co., Ltd., trade name: 1N30) having a thickness of 7 μm is used as the base material layer 10 and an adhesive (DIC) as the adhesive layer 20 using a dry laminating machine. The laminate 100 for packaging of Example 1 was created by laminating the sealant layer 30 with Graphics Co., Ltd. (trade name: LX500).
As the sealant layer 30, a linear low density polyethylene having a thickness of 60 μm and an ethylene-vinyl alcohol copolymer resin coextruded film (Tamapoly Co., Ltd., trade name: Multitron) having the same configuration as that described in the embodiment. Was used.

(Example 2)
As shown in FIG. 1 in the first embodiment, a packaging laminate 100 including a base material layer 10, an adhesive layer 20, and a sealant layer 30 was prepared as Example 2.
Specifically, Example 2 was a packaging laminate 100 in which the base material layer 10 of Example 1 was an aluminum-deposited PET film (Toray Film Processing Co., Ltd., trade name: 1010) having a thickness of 12 μm.

(Example 3)
As shown in FIG. 2 in the second embodiment, a packaging laminate 100 composed of a base material layer 10, an ink layer 40, an adhesive layer 20, an intermediate layer 50, an adhesive layer 20, and a sealant layer 30 is prepared. It was.
Specifically, an alumina-deposited PET film having a thickness of 12 μm (Letterpress Printing Co., Ltd., trade name: GL) is used as the base material layer 10, and a pattern ink (Toyo Ink Co., Ltd., trade name) is used with a gravure printing machine. : Fine Star) was applied to form an ink layer 40. Thereafter, an aluminum foil (Sumi Light Aluminum Foil Co., Ltd.) having a thickness of 7 μm as the intermediate layer 50 is obtained using an adhesive (DIC Graphics Co., Ltd., trade name: LX500) as the adhesive layer 20 using a dry laminating machine. Product name: 1N30) was laminated. Then, the laminate 100 for packaging of Example 3 was created by laminating | stacking the sealant layer 30 with the adhesive agent (DIC graphics Co., Ltd., brand name: LX500) as the contact bonding layer 20 using a dry laminating machine. .
As the sealant layer 30, a linear low density polyethylene having a thickness of 60 μm and an ethylene-vinyl alcohol copolymer resin coextruded film (Tamapoly Co., Ltd., trade name: Multitron) having the same configuration as that described in the embodiment. Was used.

Example 4
As shown in FIG. 2 in the second embodiment, a packaging laminate 100 composed of a base material layer 10, an ink layer 40, an adhesive layer 20, an intermediate layer 50, an adhesive layer 20, and a sealant layer 30 is prepared, and Example 4 It was.
Specifically, Example 4 was a packaging laminate 100 in which the intermediate layer 50 of Example 1 was an aluminum-deposited PET film (Toray Film Processing Co., Ltd., trade name: 1010) having a thickness of 12 μm.

(Example 5)
As shown in FIG. 3 in the third embodiment, a packaging laminate 100 including a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created and used as Example 5.
Specifically, an alumina-deposited PET film having a thickness of 12 μm (Letterpress Printing Co., Ltd., trade name: GL) is used as the base material layer 10, and a pattern ink (Toyo Ink Co., Ltd., trade name) is used with a gravure printing machine. : Fine Star) was applied to form an ink layer 40. Subsequently, the sealant layer 30 was laminated | stacked on the ink layer 40 with the adhesive agent (DIC graphics Inc., brand name: LX500) as the contact bonding layer 20 using the dry laminating machine.
As the sealant layer 30, a linear low density polyethylene having a thickness of 60 μm and an ethylene-vinyl alcohol copolymer resin coextruded film (Tamapoly Co., Ltd., trade name: Multitron) having the same configuration as that described in the embodiment. Was used.

(Example 6)
As shown in FIG. 3 in the third embodiment, a packaging laminate 100 including a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created as Example 6.
Specifically, Example 6 was a packaging laminate 100 in which the base material layer 10 of Example 1 was a barrier OPP film having a thickness of 30 μm (Futamura Chemical Co., Ltd., trade name: ECO-B).

(Example 7)
As shown in FIG. 3 in the third embodiment, a packaging laminate 100 including a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created and used as Example 7.
Specifically, Example 7 is a packaging laminate 100 in which the base material layer 10 of Example 1 is a 15 μm thick barrier Ny film (Gunze Co., Ltd., trade name: HP).

(Comparative Example 1)
As shown in FIG. 4, a packaging laminate 110 including a base material layer 10, an adhesive layer 20, and a sealant layer 30 was created and used as Comparative Example 1.
Specifically, Comparative Example 1 was obtained by using a linear low-density polyethylene film (Tosero Co., Ltd., trade name: TUX-FCX) having a thickness of 60 μm as the sealant layer 30 in Example 1. That is, in Comparative Example 1, the sealant layer 30 made of only the linear low density polyethylene 31 was used.

(Comparative Example 2)
As shown in FIG. 4, a packaging laminate 110 including a base material layer 10, an adhesive layer 20, and a sealant layer 30 was prepared and used as Comparative Example 2.
Specifically, in Example 2, a linear low density polyethylene film (Tosero Co., Ltd., trade name: TUX-FCX) having a thickness of 60 μm was used as the sealant layer 30 as Comparative Example 2. That is, in Comparative Example 2, the sealant layer 30 made of only the linear low density polyethylene 31 was used.

(Comparative Example 3)
As shown in FIG. 5, a packaging laminate 110 composed of a base material layer 10, an ink layer 40, an adhesive layer 20, an intermediate layer 50, an adhesive layer 20, and a sealant layer 30 was created and used as Comparative Example 3.
Specifically, in Example 3, the base material layer 10 is a PET film having a thickness of 12 μm (Toyobo Co., Ltd., trade name: E5100), and the sealant layer 30 is a linear low density having a thickness of 60 μm. A polyethylene film (Tosero Co., Ltd., trade name: TUX-FCX) was used as Comparative Example 3. That is, in Comparative Example 3, the sealant layer 30 made of only the linear low density polyethylene 31 was used.

(Comparative Example 4)
As shown in FIG. 5, a packaging laminate 110 composed of a base material layer 10, an ink layer 40, an adhesive layer 20, an intermediate layer 50, an adhesive layer 20, and a sealant layer 30 was prepared and used as Comparative Example 4.
Specifically, in Example 4, the base material layer 10 is a PET film having a thickness of 12 μm (Toyobo Co., Ltd., trade name: E5100), and the sealant layer 30 is a linear low density having a thickness of 60 μm. A polyethylene film (Tosero Co., Ltd., trade name: TUX-FCX) was used as Comparative Example 4. That is, in Comparative Example 4, the sealant layer 30 made of only the linear low density polyethylene 31 was used.

(Comparative Example 5)
As shown in FIG. 6, a laminated body 110 for packaging composed of a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created as Comparative Example 5.
Specifically, in Example 5, the base material layer 10 is a biaxially stretched polyethylene terephthalate film (Toyobo Co., Ltd., trade name: E5100) having a thickness of 12 μm, and the sealant layer 30 is a linear shape having a thickness of 60 μm. A low density polyethylene film (Tosero Co., Ltd., trade name: TUX-FCX) was used as Comparative Example 5. That is, in Comparative Example 5, the sealant layer 30 made of only the linear low density polyethylene 31 was used.

(Comparative Example 6)
As shown in FIG. 6, a laminated body 110 for packaging composed of a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created as Comparative Example 6.
Specifically, in Comparative Example 5, the base layer 10 was changed to a biaxially stretched polypropylene film (Tosero Co., Ltd., trade name: UB-1) having a thickness of 30 μm as Comparative Example 6.

(Comparative Example 7)
As shown in FIG. 6, a laminated body 110 for packaging composed of a base material layer 10, an ink layer 40, an adhesive layer 20, and a sealant layer 30 was created as Comparative Example 6.
Specifically, in Comparative Example 5, the base material layer 10 was a nylon film (Mitsubishi Resin Co., Ltd., trade name: SNR-W) having a thickness of 15 μm as Comparative Example 7.

(Evaluation method)
Each of the packaging laminates 100 of Examples 1 to 7 and the packaging laminate 110 of Comparative Examples 1 to 7 having the above-described configuration is prepared for each six bags (size of one bag: 155 mm width × 275 mm), and 30 ml of ultrapure water is added to each. Packed in an exterior bag. Then, it preserve | saved for 24 hours in a 40 degreeC thermostat, and after preservation | save, the quantity of the residual solvent (ethyl acetate) contained in ultrapure water was measured by GC / MS. Since there are many types of solvents, “ethyl acetate”, which has a high ratio among solvents used for ink and dry lamination, was used as a residual solvent management index.

(GC / MS analysis)
1 ml of the sample was put in a 20 ml vial, sealed, heated at 80 ° C. for 20 minutes, 1.0 ml of headspace gas was collected by gas tight shilling, and analyzed by GC / MS.
The results are shown in Table 1.

As can be seen from the table, the packaging laminates of Examples 1 to 7 having a three-layer structure of a linear low density polyethylene 31, an ethylene-vinyl alcohol copolymer resin 32, and a linear low density polyethylene 31 as the sealant layer 30. 100, the elution amount of ethyl acetate is drastically reduced as compared with the packaging laminate 110 of Comparative Examples 1 to 7 in which the sealant layer 30 is composed of only the linear low density polyethylene 31.
From this result, it was found that the packaging laminates 100 of Examples 1 to 7 corresponding to the embodiment of the present invention are effective against the residual solvent.

DESCRIPTION OF SYMBOLS 10 Base material layer 20 Adhesive layer 30 Sealant layer 31 Linear low density polyethylene 32 Ethylene vinyl alcohol copolymer 40 Ink layer 50 Intermediate layer 100 Laminate for packaging 110 Laminate for packaging

Claims (3)

A base material layer and a sealant layer laminated to each other ;
A printing layer formed by coating ink on the surface of the base material layer on the sealant layer side;
An intermediate layer laminated on the base material layer coated with the printing layer by dry lamination using an adhesive layer;
An infusion bag of an infusion container comprising a laminate for packaging having
The sealant layer is laminated such that a pair of linear low density polyethylene sandwiches an ethylene-vinyl alcohol copolymer resin,
The base layer and the intermediate layer are layers having gas barrier properties in which an inorganic compound is deposited,
The outer bag for an infusion container, wherein the outer bag transmits light in the stacking direction of the packaging laminate . The outer bag for an infusion container according to claim 1, wherein the base material layer contains aluminum. The intermediate layer, the outer bag infusion container according to claim 1 or 2, wherein the aluminum containing over there.

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