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JP4614473B2 - 新規なifn受容体1結合タンパク質、それらをコードするdna、およびインターフェロンに対する細胞応答の調節方法 - Google Patents

新規なifn受容体1結合タンパク質、それらをコードするdna、およびインターフェロンに対する細胞応答の調節方法 Download PDF

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JP4614473B2
JP4614473B2 JP53237098A JP53237098A JP4614473B2 JP 4614473 B2 JP4614473 B2 JP 4614473B2 JP 53237098 A JP53237098 A JP 53237098A JP 53237098 A JP53237098 A JP 53237098A JP 4614473 B2 JP4614473 B2 JP 4614473B2
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sequence
seq
dna molecule
protein
ifnar1
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JP2001508306A (ja
JP2001508306A5 (et
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レベル、マイクル
アブラモビッチ、カロライナ
イー チェバス、ジュディス
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イエダ リサーチ アンド ディベロップメント カンパニー リミテッド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1003Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007Methyltransferases (general) (2.1.1.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP53237098A 1997-01-15 1998-01-15 新規なifn受容体1結合タンパク質、それらをコードするdna、およびインターフェロンに対する細胞応答の調節方法 Expired - Fee Related JP4614473B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3563697P 1997-01-15 1997-01-15
US60/035,636 1997-01-15
PCT/US1998/000671 WO1998031796A1 (en) 1997-01-15 1998-01-15 Novel ifn receptor 1 binding proteins, dna encoding them, and methods of modulating cellular response to interferons

Publications (3)

Publication Number Publication Date
JP2001508306A JP2001508306A (ja) 2001-06-26
JP2001508306A5 JP2001508306A5 (et) 2005-08-11
JP4614473B2 true JP4614473B2 (ja) 2011-01-19

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JP53237098A Expired - Fee Related JP4614473B2 (ja) 1997-01-15 1998-01-15 新規なifn受容体1結合タンパク質、それらをコードするdna、およびインターフェロンに対する細胞応答の調節方法

Country Status (20)

Country Link
US (1) US7264945B2 (et)
EP (1) EP1019500B1 (et)
JP (1) JP4614473B2 (et)
KR (2) KR100591988B1 (et)
CN (1) CN1212398C (et)
AT (1) ATE342972T1 (et)
AU (1) AU731206C (et)
BG (1) BG64829B1 (et)
BR (1) BR9806755A (et)
CA (1) CA2276111A1 (et)
CZ (1) CZ299096B6 (et)
DE (1) DE69836226T2 (et)
DK (1) DK1019500T3 (et)
EA (1) EA003250B1 (et)
EE (1) EE04819B1 (et)
ES (1) ES2275297T3 (et)
IL (2) IL130960A0 (et)
NO (1) NO326104B1 (et)
UA (1) UA75560C2 (et)
WO (1) WO1998031796A1 (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020119129A1 (en) * 1997-01-15 2002-08-29 Yeda Research And Development Co. Ltd. Novel IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons
WO2003055506A1 (fr) * 2001-12-27 2003-07-10 Takeda Chemical Industries, Ltd. Medicaments pour la prevention et le traitement du cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4220759A1 (de) * 1992-06-24 1994-01-05 Inst Genbiologische Forschung DNA-Sequenzen für Oligosaccharid-Transporter, Plasmide, Bakterien und Pflanzen enthaltend einen Transporter sowie Verfahren zur Herstellung und Transformation von Hefestämmen zur Identifikation des Transporteers
IL107378A (en) * 1993-10-24 2005-05-17 Yeda Res & Dev SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE
US6242587B1 (en) * 1996-10-02 2001-06-05 The University Of North Carolina At Chapel Hill DNA molecules encoding a calcium-integrin binding protein

Also Published As

Publication number Publication date
EA199900663A1 (ru) 2000-02-28
AU731206B2 (en) 2001-03-29
CZ247199A3 (cs) 2000-01-12
EP1019500B1 (en) 2006-10-18
EE04819B1 (et) 2007-04-16
AU5824098A (en) 1998-08-07
IL130960A (en) 2008-03-20
KR20000070181A (ko) 2000-11-25
CN1243544A (zh) 2000-02-02
CA2276111A1 (en) 1998-07-23
EP1019500A4 (en) 2004-04-07
EE9900272A (et) 2000-02-15
US7264945B2 (en) 2007-09-04
BG64829B1 (bg) 2006-05-31
CN1212398C (zh) 2005-07-27
EA003250B1 (ru) 2003-02-27
ATE342972T1 (de) 2006-11-15
KR100591988B1 (ko) 2006-06-21
ES2275297T3 (es) 2007-06-01
AU731206C (en) 2002-05-16
KR100799828B1 (ko) 2008-01-31
KR20050046779A (ko) 2005-05-18
WO1998031796A8 (en) 1999-05-20
NO993412D0 (no) 1999-07-09
CZ299096B6 (cs) 2008-04-23
DK1019500T3 (da) 2007-02-19
WO1998031796A1 (en) 1998-07-23
DE69836226T2 (de) 2007-02-01
JP2001508306A (ja) 2001-06-26
EP1019500A2 (en) 2000-07-19
UA75560C2 (en) 2006-05-15
NO326104B1 (no) 2008-09-22
DE69836226D1 (de) 2006-11-30
IL130960A0 (en) 2001-01-28
BG103627A (en) 2000-04-28
US20030176678A1 (en) 2003-09-18
NO993412L (no) 1999-07-09
BR9806755A (pt) 2000-03-14

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