Nothing Special   »   [go: up one dir, main page]

ITRM20080342A1 - Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso. - Google Patents

Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Info

Publication number
ITRM20080342A1
ITRM20080342A1 IT000342A ITRM20080342A ITRM20080342A1 IT RM20080342 A1 ITRM20080342 A1 IT RM20080342A1 IT 000342 A IT000342 A IT 000342A IT RM20080342 A ITRM20080342 A IT RM20080342A IT RM20080342 A1 ITRM20080342 A1 IT RM20080342A1
Authority
IT
Italy
Prior art keywords
dolls
insulation
use methods
pulp cells
similar pulp
Prior art date
Application number
IT000342A
Other languages
English (en)
Inventor
Federico Ferro
Original Assignee
Univ Degli Studi Udine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Udine filed Critical Univ Degli Studi Udine
Priority to IT000342A priority Critical patent/ITRM20080342A1/it
Priority to EP09769343A priority patent/EP2313493A1/en
Priority to CN2009801335654A priority patent/CN102131918A/zh
Priority to PCT/EP2009/058015 priority patent/WO2009156495A1/en
Priority to US13/000,344 priority patent/US20110158962A1/en
Priority to JP2011515396A priority patent/JP2011525798A/ja
Publication of ITRM20080342A1 publication Critical patent/ITRM20080342A1/it
Priority to US15/046,306 priority patent/US10421947B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT000342A 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso. ITRM20080342A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
EP09769343A EP2313493A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
CN2009801335654A CN102131918A (zh) 2008-06-26 2009-06-26 牙髓髓相似细胞(dpmsc)和分离和使用的方法
PCT/EP2009/058015 WO2009156495A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
US13/000,344 US20110158962A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
JP2011515396A JP2011525798A (ja) 2008-06-26 2009-06-26 歯髄類似細胞（ｄｐｍｓｃ）ならびにその単離および使用の方法
US15/046,306 US10421947B2 (en) 2008-06-26 2016-02-17 Dental pulp marrow similar cells (DPMSC) and methods of isolating and using

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Publications (1)

Publication Number Publication Date
ITRM20080342A1 true ITRM20080342A1 (it) 2009-12-27

Family

ID=40302081

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Country Status (6)

Country Link
US (2) US20110158962A1 (it)
EP (1) EP2313493A1 (it)
JP (1) JP2011525798A (it)
CN (1) CN102131918A (it)
IT (1) ITRM20080342A1 (it)
WO (1) WO2009156495A1 (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20080342A1 (it) 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
US20150335400A1 (en) * 2009-06-17 2015-11-26 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
US9550975B2 (en) * 2009-07-15 2017-01-24 Mari Dezawa SSEA-3 pluripotent stem cell isolated from body tissue
ES2360434B1 (es) 2009-07-21 2012-04-12 Universitat Internacional De Catalunya Celulas madre pluripotenciales obtenidas a partir de la pulpa dental.
JP5608927B2 (ja) * 2010-04-13 2014-10-22 国立大学法人名古屋大学 歯髄幹細胞を用いた神経疾患治療用組成物
EP2633870B1 (en) 2012-02-29 2018-08-01 Technische Universität Berlin Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom
US10106773B2 (en) * 2012-03-01 2018-10-23 University Of Miami Isolation and use of pluripotent stem cell population from adult neural crest-derived tissues
US10041039B2 (en) 2012-03-29 2018-08-07 Jcr Pharmaceuticals Co., Ltd. Method for producing pluripotent stem cells derived from dental pulp
WO2014126176A1 (ja) * 2013-02-13 2014-08-21 国立大学法人名古屋大学 炎症性疾患の予防又は治療用組成物
US9790468B2 (en) * 2013-03-15 2017-10-17 Avita Iinternational Ltd. Multifunctional immature dental pulp stem cells and therapeutic applications
US11278574B2 (en) * 2013-03-15 2022-03-22 Avita International Ltd. Use of stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease
US11207352B2 (en) 2013-03-15 2021-12-28 Avita International Ltd. Compositions comprising stem cells expressing mesenchymal and neuronal markers and uses thereof to treat neurological disease
US11306290B2 (en) 2013-03-15 2022-04-19 Avita International Ltd. Stem cells expressing mesenchymal and neuronal markers, compositions thereof, and methods of preparation thereof
RU2714236C2 (ru) * 2014-08-14 2020-02-13 Авита Интернэшнл Лтд. Композиции стволовых клеток и способы получения стволовых клеток для применения в терапии
EP3207123A1 (en) 2014-10-17 2017-08-23 Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
WO2016086403A1 (en) * 2014-12-05 2016-06-09 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells
CN105063089A (zh) * 2015-05-19 2015-11-18 西安交通大学 hTERT重组慢病毒永生化人脱落乳牙牙髓干细胞系的方法
KR102497999B1 (ko) * 2016-03-09 2023-02-08 아비타 인터내셔널 리미티드 신경계 질환을 치료하기 위한 간엽 마커와 뉴런 마커를 발현하는 치수 줄기 세포 및 이의 조성물의 용도
WO2018106628A1 (en) 2016-12-05 2018-06-14 Children's Hospital Medical Center Colonic organoids and methods of making and using same
SG11201907134VA (en) * 2017-02-03 2019-09-27 Univ Kyushu Nat Univ Corp Method for preparing dental pulp stem cells from cells derived from dental pulp tissue
CA3082368A1 (en) * 2017-11-09 2019-05-16 Sapporo Medical University Medicine for tissue regeneration, and preparation method therefor
WO2020027163A1 (ja) * 2018-07-31 2020-02-06 Ｊｃｒファーマ株式会社 歯髄由来細胞の製造方法
CN114736957B (zh) * 2022-04-15 2024-03-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
WO2023227972A1 (en) * 2022-05-24 2023-11-30 Iceta - Instituto De Ciências, Tecnologias E Agroambiente Da Universidade Do Porto Process for preparation and cryopreservation of dental pulp from definitive teeth and products thereof based on isolated mesenchymal stem cells
WO2024075145A1 (ja) * 2022-10-03 2024-04-11 キッズウェル・バイオ株式会社 新規な歯髄幹細胞集団
WO2024075675A1 (ja) * 2022-10-03 2024-04-11 キッズウェル・バイオ株式会社 新規な歯髄幹細胞集団
WO2024172009A1 (ja) * 2023-02-14 2024-08-22 国立大学法人山口大学 間葉系細胞を含む細胞集団、細胞集団を含む医薬組成物、細胞集団から得られたエクソソーム及び細胞集団を作製する方法
CN117363565B (zh) * 2023-09-28 2024-05-17 南方医科大学口腔医院 一种用于骨再生的血管化干细胞球的构建方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4125241B2 (ja) * 2002-02-06 2008-07-30 シュティフトゥング カエザール 歯に由来する多能性胚性様幹細胞およびその使用
CA2522669C (en) 2003-04-19 2013-06-18 Songtao Shi Postnatal stem cells and uses thereof
DK2527427T3 (en) * 2003-11-20 2017-07-31 The Government Of The Us Secretary Dept Of Health And Human Services Multipotente postnatale stamceller fra humant parodontalt ligament og anvendelser deraf
ITNA20040043A1 (it) * 2004-07-28 2004-10-28 Francesco Carinci Tecnica di ingegneria tissutale ottenibile mediante isolamento di una nuova sottopopolazione di cellule staminali mbp-shed ed mbp-dpsc, isolate da polpa di denti decidui e permanenti in grado di produrre in vitro tessuto osseo umano.
EP1705245B1 (en) 2005-03-23 2009-05-20 Stiftung CAESAR Neural stem cells
US20070258957A1 (en) * 2006-05-04 2007-11-08 Russell Bowermaster Method for obtaining and storing multipotent stem cells
EP1748066B1 (en) * 2005-07-29 2008-12-31 Stiftung CAESAR Method for isolating stem cells from a pad-like tissue of teeth
US20070280907A1 (en) * 2006-04-07 2007-12-06 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Adult bone marrow cell transplantation to testes creation of transdifferentiated testes germ cells, leydig cells and sertoli cells
MX2008015645A (es) * 2006-06-09 2009-02-06 Anthrogenesis Corp Nicho placentario y uso de este para cultivar celulas primordiales.
ITRM20080342A1 (it) 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Also Published As

Publication number Publication date
JP2011525798A (ja) 2011-09-29
EP2313493A1 (en) 2011-04-27
US10421947B2 (en) 2019-09-24
US20110158962A1 (en) 2011-06-30
US20160244724A1 (en) 2016-08-25
WO2009156495A1 (en) 2009-12-30
CN102131918A (zh) 2011-07-20

Similar Documents

Publication Publication Date Title
ITRM20080342A1 (it) Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
CY1116198T1 (el) Ταυτοποιηση και απομονωση πολυδυναμων κυτταρων απο μη-οστεοχονδρινο μεσεγχυματικο ιστο
CL2019000540A1 (es) Método para aislar células madre mesenquimales a partir de membrana amniótica de cordón umbilical utilizando un medio de cultivo celular resumen de la invención.
EP2190976A4 (en) METHOD FOR PRODUCING PLURIPOTENTAL STEM CELL LENGTH CELLS
NZ601497A (en) Improved cell composition and methods of making the same
WO2010088633A3 (en) Novel cell lines and methods
WO2009133466A3 (en) Asymmetric adapter library construction
WO2012070014A3 (en) Identification of novel cell surface markers for pancreatic progenitor cells and definite endodermal cells
ZA200905374B (en) Hepatocyctes and chondrocytes from adherent placental stem cells;and cd34+cd45-placental stem cell-enriched cell populations
WO2009126250A3 (en) Reprogramming a cell by inducing a pluripotent gene through rna interference
WO2011021194A3 (en) Pericyte progenitor cells and methods of generating and using same
EP2155860A4 (en) MULTIPOTENTIAL STEM CELLS AND THEIR USE
MX2009008211A (es) Agentes que capturan celulas que presentan antigenos mediante un receptor de asialoglicoproteina de celula dendritica (dc-asgpr).
WO2012040465A3 (en) Multipotent stem cells and uses thereof
WO2009135905A3 (en) Mesenchymal stem cells and bone-forming cells
TW200740518A (en) Improvements in process operations
NO20080991L (no) Bazedoksifen acetat formuleringer
WO2009102569A3 (en) Cell lines and methods for making and using them
MY173526A (en) Novel anti-?5?1 antibodies and uses thereof
WO2009039189A3 (en) Compositions comprising stat3 sirna and methods of use thereof
CY1114310T1 (el) Νεες ανοσοενισχυτικες συνθεσεις γλυκολιπιδιου
SG195190A1 (en) Dispersion and detachment of cell aggregates
GB201305388D0 (en) Benchmarks for normal cell identification
BRPI0915092A2 (pt) composição de frutooligossacarídeo, processo para sua produção e uso
GEP20125586B (en) Novel method for synthesis of (7-methoxy-l-naphthyl)-acetonitrile and application thereof in synthesis of agomelatine