IT8221182A0 - Derivati della cefalosporina eprocedimento per la loro preparazione. - Google Patents

Derivati della cefalosporina eprocedimento per la loro preparazione.

Info

Publication number: IT8221182A0
Authority: IT; Italy
Prior art keywords: procedure; preparation; cephalosporin derivatives; cephalosporin; derivatives
Prior art date: 1981-05-12

Application number

IT8221182A

Other languages

English (en)

Other versions

IT1157275B (it

Inventor

Rudolf Lattrell

Manfred Wieduwilt

Walter Durckheimer

Jurgen Blumbach

Karl Seeger

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-05-12

Filing date

1982-05-10

Publication date

1982-05-10

1982-05-10 Application filed by Hoechst Ag filed Critical Hoechst Ag

1982-05-10 Publication of IT8221182A0 publication Critical patent/IT8221182A0/it

1987-02-11 Application granted granted Critical

1987-02-11 Publication of IT1157275B publication Critical patent/IT1157275B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT21182/82A 1981-05-12 1982-05-10 Derivati della cefalosporina e procedimento per la loro preparazione IT1157275B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19813118732 DE3118732A1 (de)	1981-05-12	1981-05-12	Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number	Publication Date
IT8221182A0 true IT8221182A0 (it)	1982-05-10
IT1157275B IT1157275B (it)	1987-02-11

Family

ID=6132055

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT21182/82A IT1157275B (it)	1981-05-12	1982-05-10	Derivati della cefalosporina e procedimento per la loro preparazione

Country Status (36)

Country	Link
US (1)	US5071979A (it)
EP (1)	EP0064740B1 (it)
JP (2)	JPS57192394A (it)
KR (1)	KR880001541B1 (it)
AR (1)	AR241186A1 (it)
AT (2)	ATE19085T1 (it)
AU (1)	AU559727B2 (it)
BE (1)	BE893163A (it)
BG (1)	BG60838B2 (it)
CA (1)	CA1228850A (it)
CH (1)	CH654312A5 (it)
CS (2)	CS248025B2 (it)
DD (1)	DD202720A5 (it)
DE (2)	DE3118732A1 (it)
DK (1)	DK166500B1 (it)
DZ (1)	DZ418A1 (it)
ES (1)	ES511955A0 (it)
FI (1)	FI70715C (it)
FR (2)	FR2511682B1 (it)
GB (2)	GB2098216A (it)
GR (1)	GR75506B (it)
HU (1)	HU186019B (it)
IE (1)	IE53296B1 (it)
IL (1)	IL65737A (it)
IT (1)	IT1157275B (it)
LU (1)	LU88736I2 (it)
MA (1)	MA19474A1 (it)
MT (1)	MTP909B (it)
NL (3)	NL8201913A (it)
NO (2)	NO162022C (it)
NZ (1)	NZ200567A (it)
PH (1)	PH20243A (it)
PT (1)	PT74877B (it)
SE (1)	SE8202961L (it)
YU (1)	YU44346B (it)
ZA (1)	ZA823226B (it)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3118732A1 (de) *	1981-05-12	1982-12-02	Hoechst Ag, 6000 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
RO84456B (ro) *	1981-09-08	1984-08-30	Eli Lilly And Co	Procedeu pentru prepararea unor derivati de cefalosporina tieno si furopiridiniu substituita
JPS5859991A (ja) *	1981-09-14	1983-04-09	Fujisawa Pharmaceut Co Ltd	新規セフェム化合物
US4501739A (en) *	1982-01-19	1985-02-26	Eli Lilly And Company	Thieno and furopyridinium-substituted cephalosporins
DE3207840A1 (de) *	1982-03-04	1983-09-15	Hoechst Ag, 6230 Frankfurt	"cephalosporinderivate und verfahren zu ihrer herstellung"
DE3374410D1 (en) *	1982-06-28	1987-12-17	Bristol Myers Co	Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
DE3247613A1 (de) *	1982-12-23	1984-07-05	Hoechst Ag, 6230 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) *	1982-12-28	1984-06-28	Hoechst Ag, 6230 Frankfurt	Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316798A1 (de) *	1983-05-07	1984-11-08	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von cephemverbindungen
DE3316797A1 (de) *	1983-05-07	1984-11-08	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von cephemverbindungen
US4690921A (en) *	1983-10-11	1987-09-01	Yamanouchi Pharmaceutical Co., Ltd.	Cephalosporin compounds and salts thereof
EP0138552A3 (en) *	1983-10-17	1986-03-19	Eli Lilly And Company	Improvements on or relating to 3-bicyclicpyridinium-methyl cephalosporins
US4692443A (en) *	1983-10-17	1987-09-08	Eli Lilly And Company	3-bicyclicpyridinium-methyl cephalosporins
JPS6094984A (ja) *	1983-10-28	1985-05-28	Dai Ichi Seiyaku Co Ltd	セフエム誘導体
GB8401093D0 (en) *	1984-01-16	1984-02-15	Fujisawa Pharmaceutical Co	Cephem compounds
JPS60169486A (ja) *	1984-02-10	1985-09-02	Yamanouchi Pharmaceut Co Ltd	７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
DE3404906A1 (de) *	1984-02-11	1985-08-14	Bayer Ag, 5090 Leverkusen	1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
IL74822A (en) *	1984-04-17	1989-06-30	Daiichi Seiyaku Co	Cephalosporin derivatives and salts thereof and their preparation
JPS60222490A (ja) *	1984-04-17	1985-11-07	Dai Ichi Seiyaku Co Ltd	セフアロスポリン誘導体およびその塩
JPS60226884A (ja) *	1984-04-25	1985-11-12	Dai Ichi Seiyaku Co Ltd	セフアロスポリン誘導体
EP0160546A3 (en) *	1984-04-26	1986-12-17	Yamanouchi Pharmaceutical Co. Ltd.	Cephalosporin compounds, and their production, and medicaments containing them
WO1985005106A1 (en) *	1984-05-09	1985-11-21	Takeda Chemical Industries, Ltd.	Cephem compounds
DE3419012A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
JPH0613530B2 (ja) *	1984-06-08	1994-02-23	武田薬品工業株式会社	セフエム化合物
GB8519606D0 (en) *	1985-08-05	1985-09-11	Fujisawa Pharmaceutical Co	3 7-d substituted-3-cephem compounds
US4714760A (en) *	1985-08-20	1987-12-22	Bristol-Myers Company	Cephalosporin intermediates
DE3775798D1 (de)	1986-03-19	1992-02-20	Banyu Pharma Co Ltd	Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel.
DE3706020A1 (de) *	1987-02-25	1988-09-08	Hoechst Ag	Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
JPH0242086A (ja) *	1988-08-02	1990-02-13	Banyu Pharmaceut Co Ltd	（３‐ヒドロキシ‐４‐ピリドン‐１‐イル）メチル基を有する新規セファロスポリン誘導体
JPH02117679A (ja) *	1989-09-22	1990-05-02	Sankyo Co Ltd	チアゾリオメチル置換基を有するセファロスポリン誘導体
US5594129A (en) *	1991-09-10	1997-01-14	Bristol-Myers Squibb Company	Process for the preparation of a cephalosporin antibiotic
US5698703A (en) *	1991-09-10	1997-12-16	Bristol-Myers Squibb Company	Syn-isomer of thiazolyl intermediate and process for the preparation thereof
EP0554004A3 (en) *	1992-01-27	1993-11-24	Katayama Seisakusho	Cephem compounds and antibacterial agents
JPH0741485A (ja) *	1993-07-30	1995-02-10	Katayama Seiyakushiyo:Kk	セフェム誘導体およびそれを含有する抗菌剤
WO1995032210A1 (en) *	1994-05-23	1995-11-30	Korea Institute Of Science And Technology	Cephalosporin compounds and processes for the preparation thereof
DE4440141A1 (de) *	1994-11-10	1996-05-15	Hoechst Ag	Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
JPH09110877A (ja)	1995-10-17	1997-04-28	Katayama Seiyakushiyo:Kk	セフェム化合物、その製造法及びそれを含有する抗菌剤
JP4064462B2 (ja) *	1996-04-04	2008-03-19	塩野義製薬株式会社	セフェム化合物及び該化合物を含有する医薬
US5929086A (en)	1996-05-10	1999-07-27	Pharmacia & Upjohn Company	Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
KR100293728B1 (ko) *	1998-05-22	2001-09-17	손 경 식	결정성세피롬황산염의제조방법
TWI335332B (en) *	2001-10-12	2011-01-01	Theravance Inc	Cross-linked vancomycin-cephalosporin antibiotics
WO2004113350A1 (en) *	2003-05-23	2004-12-29	Theravance, Inc.	Cross-linked glycopeptide - cephalosporin antibiotics
JP4754275B2 (ja) *	2005-06-13	2011-08-24	川崎重工業株式会社	壁掛機器用防振支持構造
PT3616695T (pt)	2011-09-09	2024-11-18	Merck Sharp & Dohme	Ceftolozano/tazobactam para tratar infeções intrapulmonares
CN102584856A (zh) *	2011-12-27	2012-07-18	开封豫港制药有限公司	硫酸头孢匹罗的制备方法
US8809314B1 (en)	2012-09-07	2014-08-19	Cubist Pharmacueticals, Inc.	Cephalosporin compound
US8476425B1 (en)	2012-09-27	2013-07-02	Cubist Pharmaceuticals, Inc.	Tazobactam arginine compositions
US20140274997A1 (en)	2013-03-15	2014-09-18	Cubist Pharmaceuticals, Inc.	Cephalosporin pharmaceutical compositions
US9872906B2 (en)	2013-03-15	2018-01-23	Merck Sharp & Dohme Corp.	Ceftolozane antibiotic compositions
CN110279698B (zh)	2013-03-15	2022-10-28	默沙东有限责任公司	头孢特咯瓒抗生素组合物
WO2015035376A2 (en)	2013-09-09	2015-03-12	Calixa Therapeutics, Inc.	Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en)	2013-09-27	2014-12-09	Calixa Therapeutics, Inc.	Solid forms of ceftolozane
CN108463461B (zh) *	2015-12-10	2021-11-19	奈加-Rgm制药有限公司	头孢烯化合物、其制备和用途
CN105646543B (zh) *	2016-03-17	2018-03-27	天津大学	一种头孢喹肟晶体及其制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1082962A (en) *	1963-05-28	1967-09-13	Glaxo Lab Ltd	Derivatives of 7-aminocephalosporanic acid
FR116F (it) *	1963-11-04
GB1310642A (en) *	1970-11-09	1973-03-21	Pfizer	Alpha-sulfo-and alpha-sulfoalkylacylcephalosporins
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4200746A (en) *	1974-12-20	1980-04-29	Glaxo Laboratories, Ltd.	Cephalosporins
GR63088B (en) *	1976-04-14	1979-08-09	Takeda Chemical Industries Ltd	Preparation process of novel cephalosporins
JPS6011713B2 (ja) *	1976-09-08	1985-03-27	武田薬品工業株式会社	セフアロスポリン誘導体およびその製造法
DE2716677C2 (de) *	1977-04-15	1985-10-10	Hoechst Ag, 6230 Frankfurt	Cephemderivate und Verfahren zu ihrer Herstellung
DE2714880A1 (de) *	1977-04-02	1978-10-26	Hoechst Ag	Cephemderivate und verfahren zu ihrer herstellung
AR228726A1 (es) *	1978-05-26	1983-04-15	Glaxo Group Ltd	Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
US4336353A (en) *	1979-09-11	1982-06-22	Ciba-Geigy Corporation	Salts of 3-methyl-2-(2',4'-dimethyl-phenylimino)-4-thiazoline with polymers containing sulfonic acid groups
EP0027599B1 (en) *	1979-10-12	1984-10-03	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
DE3006888A1 (de) *	1980-02-23	1981-09-10	Hoechst Ag, 6000 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
GR75644B (it) *	1980-06-18	1984-08-02	Fujisawa Pharmaceutical Co
US4367228A (en) *	1980-10-29	1983-01-04	Fujisawa Pharmaceutical Co., Ltd.	Cephem compound and composition
US4427677A (en) *	1980-12-31	1984-01-24	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
US4336253A (en) *	1981-03-11	1982-06-22	Eli Lilly And Company	Cephalosporin antibiotics
DE3118732A1 (de) *	1981-05-12	1982-12-02	Hoechst Ag, 6000 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
US4379787A (en) *	1981-10-02	1983-04-12	Eli Lilly And Company	Oximino-substituted cephalosporin compounds
US4501739A (en) *	1982-01-19	1985-02-26	Eli Lilly And Company	Thieno and furopyridinium-substituted cephalosporins
DE3248281A1 (de) *	1982-12-28	1984-06-28	Hoechst Ag, 6230 Frankfurt	Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3706020A1 (de) *	1987-02-25	1988-09-08	Hoechst Ag	Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

1981
- 1981-05-12 DE DE19813118732 patent/DE3118732A1/de not_active Withdrawn
1982
- 1982-05-06 ES ES511955A patent/ES511955A0/es active Granted
- 1982-05-07 EP EP82103989A patent/EP0064740B1/de not_active Expired
- 1982-05-07 DE DE8282103989T patent/DE3270360D1/de not_active Expired
- 1982-05-07 AR AR82289339A patent/AR241186A1/es active
- 1982-05-07 LU LU88736C patent/LU88736I2/fr unknown
- 1982-05-07 AT AT82103989T patent/ATE19085T1/de active
- 1982-05-10 NL NL8201913A patent/NL8201913A/nl not_active Application Discontinuation
- 1982-05-10 FI FI821644A patent/FI70715C/fi not_active IP Right Cessation
- 1982-05-10 CS CS823386A patent/CS248025B2/cs unknown
- 1982-05-10 YU YU983/82A patent/YU44346B/xx unknown
- 1982-05-10 IT IT21182/82A patent/IT1157275B/it active
- 1982-05-10 MT MT909A patent/MTP909B/xx unknown
- 1982-05-10 PH PH27254A patent/PH20243A/en unknown
- 1982-05-10 KR KR8202031A patent/KR880001541B1/ko active
- 1982-05-10 DD DD82239724A patent/DD202720A5/de not_active IP Right Cessation
- 1982-05-10 US US06/376,654 patent/US5071979A/en not_active Expired - Lifetime
- 1982-05-10 JP JP57078063A patent/JPS57192394A/ja active Granted
- 1982-05-10 FR FR8208066A patent/FR2511682B1/fr not_active Expired
- 1982-05-10 GR GR68118A patent/GR75506B/el unknown
- 1982-05-10 CH CH2899/82A patent/CH654312A5/de not_active IP Right Cessation
- 1982-05-10 NZ NZ200567A patent/NZ200567A/en unknown
- 1982-05-11 ZA ZA823226A patent/ZA823226B/xx unknown
- 1982-05-11 AT AT0184382A patent/AT381945B/de not_active IP Right Cessation
- 1982-05-11 HU HU821467A patent/HU186019B/hu unknown
- 1982-05-11 PT PT74877A patent/PT74877B/pt unknown
- 1982-05-11 DK DK211382A patent/DK166500B1/da not_active IP Right Cessation
- 1982-05-11 SE SE8202961A patent/SE8202961L/ not_active Application Discontinuation
- 1982-05-11 NO NO821562A patent/NO162022C/no not_active IP Right Cessation
- 1982-05-11 AU AU83589/82A patent/AU559727B2/en not_active Expired
- 1982-05-11 IL IL65737A patent/IL65737A/xx not_active IP Right Cessation
- 1982-05-11 CA CA000402656A patent/CA1228850A/en not_active Expired
- 1982-05-11 IE IE1129/82A patent/IE53296B1/en not_active IP Right Cessation
- 1982-05-12 BE BE0/208075A patent/BE893163A/fr not_active IP Right Cessation
- 1982-05-12 MA MA19680A patent/MA19474A1/fr unknown
- 1982-05-12 GB GB8213782A patent/GB2098216A/en not_active Revoked
- 1982-05-12 DZ DZ826531A patent/DZ418A1/fr active
- 1982-12-13 FR FR8220875A patent/FR2515654B1/fr not_active Expired
1984
- 1984-09-18 GB GB08423511A patent/GB2144424B/en not_active Expired
1987
- 1987-12-28 JP JP62336812A patent/JPH0670068B2/ja not_active Expired - Lifetime
1991
- 1991-12-30 CS CS914158A patent/CS415891A3/cs unknown
1994
- 1994-02-22 NL NL940003C patent/NL940003I2/nl unknown
- 1994-02-24 BG BG098550A patent/BG60838B2/bg unknown
1995
- 1995-08-08 NL NL950013C patent/NL950013I1/nl unknown
1999
- 1999-05-27 NO NO1999008C patent/NO1999008I1/no unknown

Also Published As

Publication number	Publication date
GB8423511D0 (en)	1984-10-24
ES8304143A1 (es)	1983-02-16
NO162022B (no)	1989-07-17
IT1157275B (it)	1987-02-11
IL65737A (en)	1986-11-30
PT74877B (de)	1984-11-26
EP0064740A3 (en)	1983-11-23
NL940003I1 (nl)	1994-04-05
NL8201913A (nl)	1982-12-01
CS415891A3 (en)	1992-04-15
KR830010121A (ko)	1983-12-26
ZA823226B (en)	1983-03-30
NO162022C (no)	1989-10-25
MTP909B (en)	1985-02-28
US5071979A (en)	1991-12-10
DZ418A1 (fr)	2004-09-13
NO1999008I1 (no)	1999-05-27
EP0064740A2 (de)	1982-11-17
DD202720A5 (de)	1983-09-28
DK211382A (da)	1982-11-13
KR880001541B1 (ko)	1988-08-20
CS248025B2 (en)	1987-01-15
AT381945B (de)	1986-12-10
JPS6419082A (en)	1989-01-23
FI70715C (fi)	1986-10-06
PH20243A (en)	1986-11-10
LU88736I2 (fr)	1996-08-23
AU8358982A (en)	1982-11-18
IE53296B1 (en)	1988-10-12
JPH0670068B2 (ja)	1994-09-07
AU559727B2 (en)	1987-03-19
CA1228850A (en)	1987-11-03
ATE19085T1 (de)	1986-04-15
JPH0144190B2 (it)	1989-09-26
MA19474A1 (fr)	1982-12-31
SE8202961L (sv)	1982-11-13
DE3270360D1 (en)	1986-05-15
CH654312A5 (de)	1986-02-14
YU98382A (en)	1985-08-31
FI70715B (fi)	1986-06-26
YU44346B (en)	1990-06-30
GB2144424B (en)	1986-02-12
NZ200567A (en)	1985-01-31
EP0064740B1 (de)	1986-04-09
NL940003I2 (nl)	1997-02-03
JPS57192394A (en)	1982-11-26
ATA184382A (de)	1986-05-15
AR241186A1 (es)	1992-01-31
BG60838B2 (bg)	1996-04-30
SE8202961D0 (sv)	1982-05-11
ES511955A0 (es)	1983-02-16
FI821644L (fi)	1982-11-13
IL65737A0 (en)	1982-08-31
NL950013I2 (nl)	1997-02-03
HU186019B (en)	1985-05-28
BE893163A (fr)	1982-11-12
DE3118732A1 (de)	1982-12-02
FI821644A0 (fi)	1982-05-10
GR75506B (it)	1984-07-24
GB2144424A (en)	1985-03-06
FR2511682A1 (fr)	1983-02-25
NO821562L (no)	1982-11-15
GB2098216A (en)	1982-11-17
IE821129L (en)	1982-11-12
DK166500B1 (da)	1993-06-01
FR2515654A1 (fr)	1983-05-06
PT74877A (de)	1982-06-01
FR2511682B1 (fr)	1985-06-28
NL950013I1 (nl)	1997-02-03
FR2515654B1 (fr)	1986-11-14

Publication	Publication Date	Title
IT8221182A0 (it)	1982-05-10	Derivati della cefalosporina eprocedimento per la loro preparazione.
IT8220094A0 (it)	1982-03-11	Derivati della 3,4-diidro-5h-2,3benzodiazepina e procedimento per la loro preparazione
IT8420057A0 (it)	1984-03-15	Derivati della tiazolina, procedimento per la loro preparazione e loro composizioni farmaceutiche.
IT1213103B (it)	1989-12-07	Derivati della distamicina eprocedimento per la loro preparazione.!
IT8621125A0 (it)	1986-07-15	Poli-4-aminopirrol-2-carbossamido derivati e procedimento per la loro preparazione.
IT8119814A0 (it)	1981-02-17	Derivati della piperazina e procedimenti per la loro preparazione.
IT8347826A0 (it)	1983-03-01	Derivati cefalosporinici e procedimento per la loro preparazione
IT8323800A0 (it)	1983-11-21	Cefem derivati e procedimenti per la loro preparazione.
IT8424183A0 (it)	1984-12-21	Derivati della gonadoliberina eprocedimento per la loro preparazione.
IT1185828B (it)	1987-11-18	Derivati del calcone e procedimento per la loro preparazione
IT8024150A0 (it)	1980-08-13	Derivati di alovincamone eprocedimento per la loro preparazione.
IT8320278A0 (it)	1983-03-24	Derivati delle rifamicine eprocedimento per la loro preparazione.
IT7823931A0 (it)	1978-05-29	Derivati della bromexina eprocedimento per la loro preparazione.
IT1135629B (it)	1986-08-27	N-imidzolil derivati di 1-cromano e procedimento per la loro preparazione
IT1127336B (it)	1986-05-21	Derivati della cefalosporina loro preparazione e loro impiego
IT1212412B (it)	1989-11-22	Derivati della benzo-as-triazina e procedimento per la loro preparazione.
IT8124030A0 (it)	1981-09-18	Derivati della 7-ossoprostaciclina e procedimento per la loro preparazione.
IT1157053B (it)	1987-02-11	Derivati della prolina e procedimento per la loro preparazione
IT8220637A0 (it)	1982-04-07	Cefem derivati e procedimento per la loro preparazione.
IT8249042A0 (it)	1982-08-27	Derivati imidazolici e procedimento per la loro preparazione
IT8223685A0 (it)	1982-10-08	Nuovi derivati del5-amminoisossazolo e procedimenti per la loro produzione.
IT1190711B (it)	1988-02-24	Derivati di alchilen-diammina e procedimento per la loro preparazione
IT1210711B (it)	1989-09-20	Derivati di amminopropilamminobleomicina e procedimento per la loro preparazione
IT8423507A0 (it)	1984-11-09	Derivati della 20-alchil-7-osso-prostaciclina eprocedimento per la loro preparazione.
IT8819545A0 (it)	1988-02-25	Derivati piperazinici eprocedimento per la loro preparazione.