Nothing Special   »   [go: up one dir, main page]

IT1215165B - Derivati del naftalene aventi azione retinoide procedimento per la loro preparazione e composizioni medicinali o cosmetiche che li con tengono - Google Patents

Derivati del naftalene aventi azione retinoide procedimento per la loro preparazione e composizioni medicinali o cosmetiche che li con tengono

Info

Publication number
IT1215165B
IT1215165B IT8567825A IT6782585A IT1215165B IT 1215165 B IT1215165 B IT 1215165B IT 8567825 A IT8567825 A IT 8567825A IT 6782585 A IT6782585 A IT 6782585A IT 1215165 B IT1215165 B IT 1215165B
Authority
IT
Italy
Prior art keywords
medicinal
hold
preparation
cosmetic compositions
naphthalene derivatives
Prior art date
Application number
IT8567825A
Other languages
English (en)
Other versions
IT8567825A0 (it
Inventor
Gerard Lang Jean Maignan
Serge Forestier Serge Restle
Alain Lagrange
Braham Shroot
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Publication of IT8567825A0 publication Critical patent/IT8567825A0/it
Application granted granted Critical
Publication of IT1215165B publication Critical patent/IT1215165B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/40—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals
    • C07C15/56—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals polycyclic condensed
    • C07C15/58—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals polycyclic condensed containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
    • C07C47/232—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C49/217—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C07C49/223—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/788—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with keto groups bound to a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
IT8567825A 1984-09-28 1985-09-27 Derivati del naftalene aventi azione retinoide procedimento per la loro preparazione e composizioni medicinali o cosmetiche che li con tengono IT1215165B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU85558A LU85558A1 (fr) 1984-09-28 1984-09-28 Nouveaux derives naphtaleniques a action retinoique,leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant

Publications (2)

Publication Number Publication Date
IT8567825A0 IT8567825A0 (it) 1985-09-27
IT1215165B true IT1215165B (it) 1990-01-31

Family

ID=19730329

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8567825A IT1215165B (it) 1984-09-28 1985-09-27 Derivati del naftalene aventi azione retinoide procedimento per la loro preparazione e composizioni medicinali o cosmetiche che li con tengono

Country Status (11)

Country Link
US (1) US4876381A (it)
JP (1) JP2618226B2 (it)
BE (1) BE903334A (it)
CA (2) CA1256894A (it)
CH (1) CH666679A5 (it)
DE (1) DE3534564C2 (it)
FR (1) FR2571048B1 (it)
GB (1) GB2164938B (it)
IT (1) IT1215165B (it)
LU (1) LU85558A1 (it)
NL (1) NL8502657A (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030765A (en) * 1986-05-23 1991-07-09 Hoffmann-La Roche Inc. Novel tetrahydronaphthalene and indane derivatives
ZW7487A1 (en) * 1986-05-23 1987-12-16 Hoffmann La Roche Tetrahydronaphthaline and indane derivatives
US5030764A (en) * 1986-05-23 1991-07-09 Hoffmann-La Roche Inc. Novel tetrahydronaphthalene and indane derivatives
WO1988000466A1 (en) * 1986-07-16 1988-01-28 Kligman Albert M Methods for treatment of sundamaged human skin with retinoids
AT388728B (de) * 1987-03-17 1989-08-25 Hoffmann La Roche Neue tetrahydronaphthalin- und indanderivate
FR2617476B1 (fr) * 1987-07-03 1989-11-17 Oreal Nouveaux derives polycycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique
LU87035A1 (fr) * 1987-11-04 1989-06-14 Oreal Esters du type etretinique ou apparente d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
DE3903991A1 (de) * 1989-02-10 1990-08-30 Basf Ag Phenylhydrazone des (beta)-jonons, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
DE3903989A1 (de) * 1989-02-10 1990-09-20 Basf Ag Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
DE3903988A1 (de) * 1989-02-10 1990-08-30 Basf Ag Oxidierte diphenylheteroalkane, ihre herstellung und verwendung
DE3903990A1 (de) * 1989-02-10 1990-08-30 Basf Ag Phenylhydrazone, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
US5380764A (en) * 1989-06-08 1995-01-10 Herzog; Paul Composition of vitamin A, glucose and hydrogen peroxide for cosmetic or pharmaceutical use
US5324840A (en) 1992-06-11 1994-06-28 Allergan, Inc. Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects
US5565439A (en) * 1992-11-24 1996-10-15 The Procter & Gamble Company Methods of using lysophosphatidic acid for treating hyperproliferative conditions
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US6172115B1 (en) 1993-02-11 2001-01-09 Allergan Sales, Inc. Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid
US5475022A (en) 1993-10-18 1995-12-12 Allergan, Inc. Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity
CA2137997A1 (en) * 1994-01-03 1995-07-04 John E. Starrett, Jr. Retinoid-like compounds
US5559248A (en) * 1995-04-05 1996-09-24 Bristol-Myers Squibb Co. Retinoid-like heterocycles
WO1998046228A1 (en) * 1997-04-11 1998-10-22 Bristol-Myers Squibb Company Retinoid antagonists and uses thereof
US5945561A (en) * 1997-04-30 1999-08-31 Bristol-Myers Squibb Company Retinoid-like compounds
US6008251A (en) * 1998-03-27 1999-12-28 Bristol-Myers Squibb Company Retinoid-like compounds
EP1248774B1 (en) * 1999-12-06 2009-10-07 Welichem Biotech Inc. Polyhydroxystilbenes and stilbene oxides as antipsoriatic agents and protein kinase inhibitors
US7321050B2 (en) * 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
JP2001261636A (ja) * 2000-03-21 2001-09-26 Jsr Corp Ｎ−４−ビニルベンゾイル−ｌ−システインメチルエステルおよびその重合体並びにブロック共重合体の製造方法
AU2006265971A1 (en) * 2005-06-30 2007-01-11 Ohio State Research Foundation A-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1-propenyl]benzoic acid analogs and method of manufacture and and use thereof
BRPI0817860A2 (pt) * 2007-10-22 2019-09-24 Orchid Res Laboratories Limited inibidores de histona deacetilase
CA2742909C (en) 2008-11-19 2017-12-19 Pola Chemical Industries Inc. Anti-wrinkle agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK159967C (da) * 1977-12-22 1991-06-03 Hoffmann La Roche Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater
CA1162200A (en) * 1981-02-13 1984-02-14 Michael Klaus Process for the manufacture of indanyl (or tetrahydronaphthyl)propenyl phenyl derivatives
DE3202118A1 (de) * 1982-01-23 1983-07-28 Basf Ag, 6700 Ludwigshafen Substituierte vinylbenzoesaeure-derivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen

Also Published As

Publication number Publication date
GB2164938A (en) 1986-04-03
BE903334A (fr) 1986-03-27
CA1256894A (fr) 1989-07-04
JPS61233636A (ja) 1986-10-17
FR2571048B1 (fr) 1988-08-05
GB2164938B (en) 1988-02-10
NL8502657A (nl) 1986-04-16
DE3534564C2 (de) 1995-10-26
CH666679A5 (fr) 1988-08-15
LU85558A1 (fr) 1986-04-03
JP2618226B2 (ja) 1997-06-11
FR2571048A1 (fr) 1986-04-04
AU4797085A (en) 1986-04-10
GB8523817D0 (en) 1985-10-30
AU590217B2 (en) 1989-11-02
DE3534564A1 (de) 1986-04-03
US4876381A (en) 1989-10-24
CA1256378A (fr) 1989-06-27
IT8567825A0 (it) 1985-09-27

Similar Documents

Publication Publication Date Title
IT1215165B (it) Derivati del naftalene aventi azione retinoide procedimento per la loro preparazione e composizioni medicinali o cosmetiche che li con tengono
IT8648157A0 (it) Derivati del tiazolo, loro preparazione e composizioni farmaceutiche che li contengono
IT1203552B (it) Derivati naftalenici aventi azione di tipo retinoide procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li contengono
IT8567757A0 (it) Derivati di benzonorbornene procedimento per la loro preparazione e composizioni medicinali e cosmetiche che li contengono
IT8468241A0 (it) Derivati del triptofano farmaceuti camente attivi e composizioni farmaceutiche che li contengono
IT1209603B (it) Derivati 2,6-disostituiti di naftalene, procedimento per prepararli e loro uso nel campo farmaceutico e cosmetico.
IT8423564A0 (it) Derivati della 7-carbossimetossi-furo-(3,4-c)-piri dina, loro preparazione e composizioni farmaceutiche che licontengono.
IT1203791B (it) Derivati del morfinano e della morfina,loro preparazione,loro impiego come medicamenti e e le composizioni farmaceutiche che li contengono
IT1176770B (it) Derivati del benzossazolone e del benzotiazolone pro cedimenti per la loro preparazione e compozione farmaceutica che li contiene
IT8249457A0 (it) Derivati del ciclopropano, loro procedimento di preparazione, loro impiego come agenti profumanti e composizioni che li contengono
IT1224226B (it) Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono
IT1182061B (it) Derivati di amminofenolo, procedimento per prepararli e composizione farmaceutica che li contiene
IT1172149B (it) Derivati del benzopirano e del benzotiopirano loro preparazione e loro impiego come medicamenti
IT1196411B (it) Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono
IT1185828B (it) Derivati del calcone e procedimento per la loro preparazione
IT1197655B (it) Derivati del 2(hi)-piridinone,loro preparazione e loro impiego come medicamenti
IT1193590B (it) Derivati amino-alchil-solfonici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT8667976A0 (it) Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
IT1227456B (it) Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono
IT1129305B (it) Derivati di 1,2,4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT8348162A0 (it) Derivati della pleuromutilina, loro preparazione e loro impiego come medicamenti
IT1200079B (it) Derivati della naftossazina, loro preparazione, loro applicazione come medicamenti e composizioni farmaceutiche che li contengono
IT1194281B (it) Derivati di piridazinoni impiegabili come sostanze medicinali e procedimento per la loro fabricazione
IT1168389B (it) Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono
IT8567725A0 (it) Li contengono derivati 1-sostituiti del 4-metossi-2,3,6-trimetilbenzene loro procedimento di preparazione e composizioni medicamentose e cosmetiche che

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970717