IT1196411B - Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono - Google Patents

Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono

Info

Publication number: IT1196411B
Authority: IT; Italy
Prior art keywords: ergolinic; derivatives; preparation; compositions containing; therapeutic compositions
Prior art date: 1979-12-06

Application number

IT26488/80A

Other languages

English (en)

Other versions

IT8026488A0 (it

Inventor

Luigi Bernardi

Germano Bosisio

Sergio Mantegani

Alessandro Rossi

Aldemio Temperilli

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-12-06

Filing date

1980-12-05

Publication date

1988-11-16

1980-12-05 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1980-12-05 Publication of IT8026488A0 publication Critical patent/IT8026488A0/it

1988-11-16 Application granted granted Critical

1988-11-16 Publication of IT1196411B publication Critical patent/IT1196411B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT26488/80A 1979-12-06 1980-12-05 Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono IT1196411B (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB7942079		1979-12-06
GB8007029		1980-03-01
GB8017518		1980-05-29

Publications (2)

Publication Number	Publication Date
IT8026488A0 IT8026488A0 (it)	1980-12-05
IT1196411B true IT1196411B (it)	1988-11-16

Family

ID=27260819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT26488/80A IT1196411B (it)	1979-12-06	1980-12-05	Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono

Country Status (14)

Country	Link
US (1)	US4382940A (it)
EP (1)	EP0030351B1 (it)
AU (1)	AU537581B2 (it)
CA (1)	CA1153367A (it)
DE (1)	DE3068911D1 (it)
DK (1)	DK518580A (it)
FI (1)	FI67081C (it)
FR (1)	FR2471381A1 (it)
HU (1)	HU185020B (it)
IE (1)	IE51187B1 (it)
IL (1)	IL61614A (it)
IT (1)	IT1196411B (it)
SU (1)	SU1034606A3 (it)
YU (1)	YU309080A (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2120242A (en) *	1982-04-30	1983-11-30	Erba Farmitalia	Ergoline derivatives
CH649998A5 (de) *	1982-08-09	1985-06-28	Sandoz Ag	Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
DE3413660A1 (de) *	1984-04-09	1985-10-17	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten
DE3587860D1 (de) *	1984-04-09	1994-07-28	Schering Ag	2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4683313A (en) *	1985-06-24	1987-07-28	Eli Lilly And Company	2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3535930A1 (de) *	1985-10-04	1987-04-09	Schering Ag	Neue 2-substituierte ergolinderivate
GB8615471D0 (en) *	1986-06-25	1986-07-30	Erba Farmitalia	T-butyl ergoline derivatives
DE3938701A1 (de) *	1989-11-20	1991-05-23	Schering Ag	Neue agroclavin- und elymoclavin-derivate, verfahren zu deren herstellung und deren verwendung in arzneimitteln
JP3337688B2 (ja) *	1992-12-24	2002-10-21	フアルマシア・エ・アツプジヨン・エツセ・ピー・アー	セロトニン作動性エルゴリン誘導体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL278401A (it) *	1961-05-29
US3228943A (en) *	1962-06-11	1966-01-11		Lumilysergol derivatives
GB1191099A (en) *	1968-03-07	1970-05-06	Farmaceutici Italia	Ergoline Derivatives
IE41533B1 (en) *	1974-03-14	1980-01-30	Sandoz Ltd	Thiomethyl ergolene derivatives
US3901894A (en) *	1974-06-06	1975-08-26	Lilly Co Eli	8-thiomethylergolines
US3968111A (en) *	1974-12-06	1976-07-06	Eli Lilly And Company	8,8-Disubstituted-6-methylergolines and related compounds
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
IT1192260B (it) *	1977-07-05	1988-03-31	Simes	Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
IT1094965B (it) *	1978-04-05	1985-08-10	Corvi Mora E	Procedimento di preparazione di derivati del lisergolo

1980
- 1980-12-01 US US06/211,920 patent/US4382940A/en not_active Expired - Lifetime
- 1980-12-02 AU AU64958/80A patent/AU537581B2/en not_active Ceased
- 1980-12-02 DE DE8080107522T patent/DE3068911D1/de not_active Expired
- 1980-12-02 FR FR8025571A patent/FR2471381A1/fr active Granted
- 1980-12-02 FI FI803736A patent/FI67081C/fi not_active IP Right Cessation
- 1980-12-02 EP EP80107522A patent/EP0030351B1/en not_active Expired
- 1980-12-02 CA CA000365922A patent/CA1153367A/en not_active Expired
- 1980-12-02 IL IL61614A patent/IL61614A/xx unknown
- 1980-12-04 DK DK518580A patent/DK518580A/da not_active Application Discontinuation
- 1980-12-05 IT IT26488/80A patent/IT1196411B/it active
- 1980-12-05 HU HU802916A patent/HU185020B/hu unknown
- 1980-12-05 IE IE2558/80A patent/IE51187B1/en unknown
- 1980-12-05 SU SU803212054A patent/SU1034606A3/ru active
- 1980-12-05 YU YU03090/80A patent/YU309080A/xx unknown

Also Published As

Publication number	Publication date
FI67081C (fi)	1985-01-10
AU6495880A (en)	1981-06-11
FI67081B (fi)	1984-09-28
FI803736L (fi)	1981-06-07
FR2471381B1 (it)	1983-01-07
IT8026488A0 (it)	1980-12-05
IL61614A0 (en)	1981-01-30
FR2471381A1 (fr)	1981-06-19
IE802558L (en)	1981-06-06
CA1153367A (en)	1983-09-06
EP0030351B1 (en)	1984-08-08
EP0030351A2 (en)	1981-06-17
DE3068911D1 (en)	1984-09-13
US4382940A (en)	1983-05-10
DK518580A (da)	1981-06-07
SU1034606A3 (ru)	1983-08-07
AU537581B2 (en)	1984-07-05
HU185020B (en)	1984-11-28
YU309080A (en)	1983-02-28
IL61614A (en)	1984-04-30
IE51187B1 (en)	1986-10-29
EP0030351A3 (en)	1981-12-02

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