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IN2015DN01164A - - Google Patents

Info

Publication number
IN2015DN01164A
IN2015DN01164A IN1164DEN2015A IN2015DN01164A IN 2015DN01164 A IN2015DN01164 A IN 2015DN01164A IN 1164DEN2015 A IN1164DEN2015 A IN 1164DEN2015A IN 2015DN01164 A IN2015DN01164 A IN 2015DN01164A
Authority
IN
India
Prior art keywords
compositions
compounds
apis
preparation
dosage forms
Prior art date
Application number
Other languages
English (en)
Inventor
Keith Mccarthy
Joshua R Giguere
Stuart James Gebbie
Lonn S Rider
Original Assignee
Rhodes Technologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodes Technologies filed Critical Rhodes Technologies
Publication of IN2015DN01164A publication Critical patent/IN2015DN01164A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
IN1164DEN2015 2012-07-16 2015-02-12 IN2015DN01164A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672265P 2012-07-16 2012-07-16
US201361762657P 2013-02-08 2013-02-08
PCT/IB2013/001538 WO2014013311A1 (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Publications (1)

Publication Number Publication Date
IN2015DN01164A true IN2015DN01164A (es) 2015-06-26

Family

ID=48916126

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1164DEN2015 IN2015DN01164A (es) 2012-07-16 2015-02-12

Country Status (22)

Country Link
US (4) US20150259355A1 (es)
EP (1) EP2877473B1 (es)
JP (1) JP6236446B2 (es)
KR (1) KR101946104B1 (es)
CN (1) CN104507947B (es)
AR (1) AR091779A1 (es)
AU (2) AU2013291723B2 (es)
BR (1) BR112015000867A2 (es)
CA (1) CA2879268C (es)
CO (1) CO7180189A2 (es)
EA (1) EA029925B1 (es)
ES (1) ES2638178T3 (es)
HK (1) HK1210171A1 (es)
IL (1) IL236711B (es)
IN (1) IN2015DN01164A (es)
MX (1) MX362186B (es)
NZ (2) NZ715111A (es)
PH (1) PH12015500088A1 (es)
SG (1) SG11201407986QA (es)
TW (2) TWI588147B (es)
UA (1) UA117226C2 (es)
WO (1) WO2014013311A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR092858A1 (es) 2012-07-16 2015-05-06 Rhodes Tech Procedimiento para una sintesis mejorada de opioide
SG11201407986QA (en) 2012-07-16 2015-02-27 Rhodes Technologies Process for improved opioid synthesis
US9062062B1 (en) 2013-12-18 2015-06-23 Cody Laboratories, Inc. Synthesis of oxycodone hydrochloride
US8846923B1 (en) * 2013-12-18 2014-09-30 Cody Laboratories, Inc. Preparation of 14-hydroxycodeinone sulfate
CN106164078A (zh) * 2013-12-18 2016-11-23 科迪实验室公司 氧可酮盐酸盐的合成
US10227354B2 (en) 2013-12-18 2019-03-12 Cody Laboratories, Inc. Conversion of oxycodone base to oxycodone hydrochloride
CA2937006C (en) 2014-01-15 2018-12-04 Rhodes Technologies Process for improved oxycodone synthesis
CA2937007C (en) 2014-01-15 2018-11-06 Rhodes Technologies Process for improved oxymorphone synthesis
US20160052932A1 (en) * 2014-08-25 2016-02-25 Johnson Matthey Public Limited Company Processes for Making Opioids Including 14-Hydroxycodeinone and 14-hydroxymorphinone
CA3067718A1 (en) 2017-06-20 2018-12-27 Johnson Matthey Public Limited Company Hydrogenation process for preparing oxycodone hydrochloride from 14-hydroxycodeinone
KR102120720B1 (ko) * 2018-07-16 2020-06-10 연성정밀화학(주) 날푸라핀 함유 구강붕해정
CN114573508B (zh) * 2020-12-01 2024-07-23 绍兴赜军生物医药科技有限公司 羟考酮类化合物、其中间体及制备方法
US11247999B1 (en) 2021-07-02 2022-02-15 Joseph DeGraw Facile conversion of morphine to normorphine
CN114276358B (zh) * 2022-01-07 2023-09-12 北京华素制药股份有限公司 羟考酮盐酸盐的多晶型物及其制备方法和用途

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2772270A (en) 1954-10-21 1956-11-27 M J Lewenstein 14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone
US3173876A (en) 1960-05-27 1965-03-16 John C Zobrist Cleaning methods and compositions
NL271831A (es) 1960-11-29
US3276586A (en) 1963-08-30 1966-10-04 Rosaen Filter Co Indicating means for fluid filters
NL6714885A (es) 1967-11-02 1969-05-06
US3541006A (en) 1968-07-03 1970-11-17 Amicon Corp Ultrafiltration process
US3541005A (en) 1969-02-05 1970-11-17 Amicon Corp Continuous ultrafiltration of macromolecular solutions
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1478759A (en) 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4063064A (en) 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4200098A (en) 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4861598A (en) 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
DE3812567A1 (de) 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
US5215758A (en) 1991-09-11 1993-06-01 Euroceltique, S.A. Controlled release matrix suppository for pharmaceuticals
US5472712A (en) 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5286493A (en) 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5273760A (en) 1991-12-24 1993-12-28 Euroceltigue, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5324351A (en) 1992-08-13 1994-06-28 Euroceltique Aqueous dispersions of zein and preparation thereof
MXPA04000584A (es) * 2001-07-18 2004-04-20 Euro Celtique Sa COMBINACIONES FARMACeUTICAS DE OXICODONA Y NALOXONA.
US6864370B1 (en) * 2003-06-05 2005-03-08 Zhaiwei Lin Process for manufacturing oxycodone
US20050203115A1 (en) * 2004-03-10 2005-09-15 Sancilio Frederick D. Narcotic-NSAID ion pairs
TWI365880B (en) * 2004-03-30 2012-06-11 Euro Celtique Sa Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp
SK286087B6 (sk) 2004-08-18 2008-03-05 Zentiva, A. S. Spôsob prípravy oxykodonu
GB0421149D0 (en) 2004-09-23 2004-10-27 Johnson Matthey Plc Preparation of oxycodone
SK286233B6 (sk) 2004-11-15 2008-05-06 Zentiva, A. S. Spôsob izolácie 14-hydroxykodeinonu
US8703099B2 (en) * 2005-02-24 2014-04-22 Dr Pharma Nova, Llc Registry method and control system for DEA schedule II-V medicines
CN101198612A (zh) 2005-06-16 2008-06-11 马林克罗特公司 通过1-卤代-蒂巴因或类似物制备14-羟基阿片类的合成路线
KR100753432B1 (ko) 2005-11-08 2007-08-31 경희대학교 산학협력단 다결정 실리콘 및 그의 결정화 방법
US20070117826A1 (en) * 2005-11-23 2007-05-24 Forest Laboratories, Inc. Pharmaceutical formulations comprising ibuprofen, oxycodone, and 14-hydroxycodeinone
CN101395159A (zh) 2006-03-02 2009-03-25 马林克罗特公司 制备含有低含量α,β-不饱和酮化合物的吗啡烷-6-酮产物的方法
CA2671518C (en) * 2006-12-04 2016-06-07 Noramco, Inc. Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone
CN101652369A (zh) 2006-12-04 2010-02-17 诺拉姆科有限公司 减少羟考酮碱中杂质的方法
GB0624880D0 (en) 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics
ES2438997T5 (es) 2007-03-23 2024-09-03 SpecGx LLC Preparación mejorada de oximorfona a partir de oripavina
US8309727B2 (en) 2007-04-16 2012-11-13 Mallinckrodt Llc Opiate reduction utilizing catalytic hydrogen transfer reaction
GB2450691A (en) 2007-07-02 2009-01-07 Alpharma Aps One-pot preparation of oxycodone from thebaine
JP5663791B2 (ja) 2009-06-03 2015-02-04 高砂香料工業株式会社 不斉水素化触媒
WO2011032214A1 (en) 2009-09-16 2011-03-24 Monash University A method for the n-demethylation of n-methyl heterocycles
EP2377866B1 (en) * 2010-03-23 2014-02-26 Siegfried AG Preparation of low impurity opiates in a continuous flow reactor
JP2013529595A (ja) 2010-06-11 2013-07-22 ローズ テクノロジーズ 第３級アミンのｎ−脱アルキル化方法
ES2659168T3 (es) * 2010-07-02 2018-03-14 Johnson Matthey Public Limited Company Proceso para la síntesis y purificación de oxicodona
JP5728084B2 (ja) 2010-07-08 2015-06-03 アルカーメス ファーマ アイルランド リミテッド 置換モルフィナンの合成のための方法
JP5780933B2 (ja) 2010-12-01 2015-09-16 高砂香料工業株式会社 光学活性メントールの製造方法
AU2013274407B2 (en) 2012-06-11 2017-06-22 Siegfried Ag Improved method of preparing oxymorphone
SG11201407986QA (en) 2012-07-16 2015-02-27 Rhodes Technologies Process for improved opioid synthesis
AR092858A1 (es) 2012-07-16 2015-05-06 Rhodes Tech Procedimiento para una sintesis mejorada de opioide
CN103113378B (zh) 2013-02-20 2016-04-06 北京华素制药股份有限公司 一种盐酸羟吗啡酮的合成方法
CN103433076B (zh) 2013-09-02 2015-06-24 浙江新和成股份有限公司 一种固载型不对称催化剂及其在不对称氢化反应中的应用
US9060620B1 (en) 2013-12-04 2015-06-23 Yogi Realty LLC Baby restraining article
US10227354B2 (en) 2013-12-18 2019-03-12 Cody Laboratories, Inc. Conversion of oxycodone base to oxycodone hydrochloride
US9062062B1 (en) 2013-12-18 2015-06-23 Cody Laboratories, Inc. Synthesis of oxycodone hydrochloride
CN106164078A (zh) 2013-12-18 2016-11-23 科迪实验室公司 氧可酮盐酸盐的合成
US8846923B1 (en) 2013-12-18 2014-09-30 Cody Laboratories, Inc. Preparation of 14-hydroxycodeinone sulfate
CA2937006C (en) 2014-01-15 2018-12-04 Rhodes Technologies Process for improved oxycodone synthesis
CA2937007C (en) 2014-01-15 2018-11-06 Rhodes Technologies Process for improved oxymorphone synthesis

Also Published As

Publication number Publication date
CN104507947B (zh) 2017-06-27
NZ628695A (en) 2016-02-26
KR101946104B1 (ko) 2019-02-08
UA117226C2 (uk) 2018-07-10
US20190308986A1 (en) 2019-10-10
HK1210171A1 (en) 2016-04-15
PH12015500088B1 (en) 2015-03-02
TW201639855A (zh) 2016-11-16
US11390627B2 (en) 2022-07-19
IL236711A0 (en) 2015-02-26
US20150259355A1 (en) 2015-09-17
TW201416368A (zh) 2014-05-01
AU2013291723A1 (en) 2014-12-18
EP2877473B1 (en) 2017-06-14
MX2015000880A (es) 2016-09-07
TWI588147B (zh) 2017-06-21
MX362186B (es) 2019-01-08
EA201590221A1 (ru) 2016-05-31
NZ715111A (en) 2016-12-23
EP2877473A1 (en) 2015-06-03
CA2879268C (en) 2018-05-08
BR112015000867A2 (pt) 2019-10-15
CN104507947A (zh) 2015-04-08
US20210094964A1 (en) 2021-04-01
EA029925B1 (ru) 2018-05-31
AR091779A1 (es) 2015-02-25
WO2014013311A1 (en) 2014-01-23
SG11201407986QA (en) 2015-02-27
JP2015524406A (ja) 2015-08-24
US20180111946A1 (en) 2018-04-26
ES2638178T3 (es) 2017-10-19
US10202396B2 (en) 2019-02-12
KR20150029753A (ko) 2015-03-18
JP6236446B2 (ja) 2017-11-22
AU2013291723B2 (en) 2016-07-28
CA2879268A1 (en) 2014-01-23
CO7180189A2 (es) 2015-02-09
PH12015500088A1 (en) 2015-03-02
IL236711B (en) 2018-04-30
AU2016204929A1 (en) 2016-08-04

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