IL123889A0 - Pharmaceutical angiostatic dipeptide compositions and methods of use thereof - Google Patents

Pharmaceutical angiostatic dipeptide compositions and methods of use thereof

Info

Publication number: IL123889A0
Authority: IL; Israel
Prior art keywords: methods; pharmaceutical; angiostatic; dipeptide; compositions
Prior art date: 1995-10-03

Application number

IL12388996A

Other languages

English (en)

Original Assignee

Cytran Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-03

Filing date

1996-10-02

Publication date

1998-10-30

1996-10-02 Application filed by Cytran Ltd filed Critical Cytran Ltd

1998-10-30 Publication of IL123889A0 publication Critical patent/IL123889A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)

IL12388996A 1995-10-03 1996-10-02 Pharmaceutical angiostatic dipeptide compositions and methods of use thereof IL123889A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US53870195A	1995-10-03	1995-10-03
US08/614,764 US5902790A (en)	1995-10-03	1996-03-13	Pharmaceutical angiostatic dipeptide compositions and method of use thereof
PCT/US1996/015856 WO1997012625A1 (en)	1995-10-03	1996-10-02	Pharmaceutical angiostatic dipeptide compositions and methods of use thereof

Publications (1)

Publication Number	Publication Date
IL123889A0 true IL123889A0 (en)	1998-10-30

Family

ID=27065900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12388996A IL123889A0 (en)	1995-10-03	1996-10-02	Pharmaceutical angiostatic dipeptide compositions and methods of use thereof

Country Status (23)

Country	Link
US (4)	US5902790A (de)
EP (1)	EP0869808B1 (de)
JP (2)	JP3679129B2 (de)
KR (1)	KR100483779B1 (de)
CN (1)	CN1128636C (de)
AT (1)	ATE332702T1 (de)
AU (1)	AU714846B2 (de)
BR (1)	BR9610838A (de)
CA (1)	CA2233457C (de)
CZ (1)	CZ298345B6 (de)
DE (1)	DE69636343T2 (de)
DK (1)	DK0869808T3 (de)
EA (1)	EA001146B1 (de)
ES (1)	ES2268710T3 (de)
HU (1)	HUP9902105A3 (de)
IL (1)	IL123889A0 (de)
MX (1)	MX9802564A (de)
NO (1)	NO326298B1 (de)
NZ (1)	NZ319907A (de)
PL (1)	PL186123B1 (de)
SK (1)	SK283677B6 (de)
TR (1)	TR199800653T1 (de)
WO (1)	WO1997012625A1 (de)

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ATE547101T1 (de)	2000-08-04	2012-03-15	Dmi Biosciences Inc	Verfahren zur verwendung von diketopiperazinen und zusammensetzungen, die diese enthalten
DE10100052A1 (de) *	2001-01-02	2002-07-11	Inst Medizintechnologie Magdeb	Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
CN100579582C (zh) *	2001-01-02	2010-01-13	Imtm股份有限公司	联合应用酶抑制剂及其药学组合物在制备治疗和预防动脉硬化、预防和治疗根据杰尔－库姆斯分类法分类的ⅰ型过敏反应以及治疗和预防与毛囊和表皮角化过度和角质细胞的过度增殖相关的皮肤疾病的药物中的用途
US20030087830A1 (en) *	2001-06-12	2003-05-08	Eric Dupont	Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
AU2004241101B2 (en)	2003-05-15	2010-05-13	Ampio Pharmaceuticals, Inc.	Treatment of T-cell mediated diseases
WO2005016326A2 (en) *	2003-07-11	2005-02-24	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Analogs of thalidomide as potential angiogenesis inhibitors
CA2538864C (en)	2003-09-17	2013-05-07	The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services	Thalidomide analogs as tnf-alpha modulators
US8952895B2 (en)	2011-06-03	2015-02-10	Apple Inc.	Motion-based device operations
US20080233053A1 (en) *	2005-02-07	2008-09-25	Pharmalight Inc.	Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
CA2569204A1 (en)	2006-11-28	2008-05-28	Apotex Technologies Inc.	Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) *	2006-12-19	2008-06-19	Apotex Technologies Inc.	Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
CN101657210A (zh) *	2007-02-13	2010-02-24	希克龙制药公司	粘膜疾病引起的组织退化、损伤或损害的治疗或预防方法
CA2579119C (en)	2007-02-16	2013-03-05	Apotex Technologies Inc.	Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
US20110189305A1 (en) *	2007-08-23	2011-08-04	Tuthill Cynthia W	Treatment of lung cancer
WO2009146320A1 (en)	2008-05-27	2009-12-03	Dmi Life Sciences, Inc.	Therapeutic methods and compounds
DE102008032828A1 (de) *	2008-07-02	2010-01-07	Technische Universität Dresden	Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
CA2810844C (en)	2010-09-07	2017-03-21	Dmi Acquisition Corp.	Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions
US9925300B2 (en)	2011-10-10	2018-03-27	Ampio Pharmaceuticals, Inc.	Implantable medical devices with increased immune tolerance, and methods for making and implanting
MY167804A (en)	2011-10-10	2018-09-26	Ampio Pharmaceuticals Inc	Treatment of degenerative joint disease
SG11201400283RA (en)	2011-10-28	2014-03-28	Ampio Pharmaceuticals Inc	Treatment of rhinitis
US8927725B2 (en)	2011-12-02	2015-01-06	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Thio compounds
CN102631464B (zh) *	2012-05-18	2013-07-31	崔新明	一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
AU2014232728B2 (en)	2013-03-15	2019-02-21	Ampio Pharmaceuticals, Inc.	Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP4066836A1 (de)	2014-08-18	2022-10-05	Ampio Pharmaceuticals, Inc.	Behandlung von gelenkerkrankungen
US9925233B2 (en)	2015-01-30	2018-03-27	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en)	2015-01-30	2017-08-29	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en)	2015-01-30	2017-06-27	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US9744239B2 (en)	2015-01-30	2017-08-29	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en)	2015-01-30	2018-04-10	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en)	2015-01-30	2017-09-05	Par Pharmaceutical, Inc.	Vasopressin formulations for use in treatment of hypotension
US11389512B2 (en)	2015-06-22	2022-07-19	Ampio Pharmaceuticals, Inc.	Use of low molecular weight fractions of human serum albumin in treating diseases
CN111344002A (zh) *	2017-08-31	2020-06-26	新加坡保健服务集团	用于治疗视网膜血管生成性疾病的Angio-3
CN116874557A (zh) *	2023-08-01	2023-10-13	首都医科大学	2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用

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CH611878A5 (de) *	1974-07-04	1979-06-29	Takeda Chemical Industries Ltd
US4191753A (en) *	1978-11-06	1980-03-04	University Of Miami	Anti-hypertensive peptide analogs
US5728680A (en) *	1987-12-30	1998-03-17	Cytoven J.V.	Methods for normalizing numbers of lymphocytes
DE3873327D1 (de) *	1987-12-30	1992-09-03	Vsesojuznyj Kardiologitsches	Arzneimittelzubereitung zur behandlung des immunmangels.
GR1000608B (el) *	1988-07-21	1992-08-31	Erba Carlo Spa	Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) *	1988-12-21	1991-04-15	Ростовский медицинский институт	Способ лечени синуитов у детей
US5902790A (en) *	1995-10-03	1999-05-11	Cytran, Inc.	Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US5770576A (en) *	1989-08-30	1998-06-23	Cytran, Inc.	Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
RU1827255C (ru) *	1990-10-22	1993-07-15	Киевский государственный институт усовершенствования врачей	Способ лечени туберкулеза легких
JP3068656B2 (ja) *	1991-03-07	2000-07-24	アピ株式会社	新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
CA2107460A1 (en) *	1991-04-01	1992-10-02	Vladimir K. Khavinson	Pharmaceutical dipeptide compositions and methods of use thereof
RU2014063C1 (ru) *	1991-04-23	1994-06-15	Сочинский научно-исследовательский институт курортологии и физиотерапии	Способ лечения подострых воспалительных заболеваний гениталий
AU2905092A (en) *	1991-10-28	1993-06-07	Cytoven	Pharmaceutical dipeptide compositions and methods of use thereof
WO1995003067A1 (en) *	1993-07-21	1995-02-02	Khavinson Vladimir Khatskelevi	Pharmaceutical with immunomodulating activity
JPH09503205A (ja) *	1993-09-24	1997-03-31	ザユニバーシティオブサザーンカリフォルニア	組織修復におけるアンギオテンシン▲ｉｉ▼類似体の使用

1996
- 1996-03-13 US US08/614,764 patent/US5902790A/en not_active Expired - Lifetime
- 1996-10-02 NZ NZ319907A patent/NZ319907A/xx not_active IP Right Cessation
- 1996-10-02 WO PCT/US1996/015856 patent/WO1997012625A1/en active IP Right Grant
- 1996-10-02 BR BR9610838-0A patent/BR9610838A/pt not_active Application Discontinuation
- 1996-10-02 DE DE69636343T patent/DE69636343T2/de not_active Expired - Lifetime
- 1996-10-02 CZ CZ0091398A patent/CZ298345B6/cs not_active IP Right Cessation
- 1996-10-02 DK DK96934021T patent/DK0869808T3/da active
- 1996-10-02 CA CA002233457A patent/CA2233457C/en not_active Expired - Lifetime
- 1996-10-02 TR TR1998/00653T patent/TR199800653T1/xx unknown
- 1996-10-02 EP EP96934021A patent/EP0869808B1/de not_active Expired - Lifetime
- 1996-10-02 JP JP51441597A patent/JP3679129B2/ja not_active Expired - Lifetime
- 1996-10-02 AT AT96934021T patent/ATE332702T1/de not_active IP Right Cessation
- 1996-10-02 IL IL12388996A patent/IL123889A0/xx unknown
- 1996-10-02 KR KR1019980702431A patent/KR100483779B1/ko not_active IP Right Cessation
- 1996-10-02 ES ES96934021T patent/ES2268710T3/es not_active Expired - Lifetime
- 1996-10-02 PL PL96326149A patent/PL186123B1/pl unknown
- 1996-10-02 HU HU9902105A patent/HUP9902105A3/hu unknown
- 1996-10-02 EA EA199800357A patent/EA001146B1/ru not_active IP Right Cessation
- 1996-10-02 AU AU72540/96A patent/AU714846B2/en not_active Expired
- 1996-10-02 CN CN96197430A patent/CN1128636C/zh not_active Expired - Lifetime
- 1996-10-02 SK SK423-98A patent/SK283677B6/sk not_active IP Right Cessation
1998
- 1998-03-30 NO NO19981436A patent/NO326298B1/no not_active IP Right Cessation
- 1998-04-01 MX MX9802564A patent/MX9802564A/es unknown
1999
- 1999-03-01 US US09/260,190 patent/US6096713A/en not_active Expired - Lifetime
2000
- 2000-02-17 US US09/506,430 patent/US6911431B1/en not_active Expired - Fee Related
2005
- 2005-03-15 JP JP2005074079A patent/JP2005194287A/ja not_active Withdrawn
- 2005-05-16 US US11/129,367 patent/US20060094665A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PL326149A1 (en)	1998-08-31
DK0869808T3 (da)	2006-11-13
TR199800653T1 (xx)	1998-06-22
NO326298B1 (no)	2008-11-03
EA199800357A1 (ru)	1998-10-29
JP2005194287A (ja)	2005-07-21
US20060094665A1 (en)	2006-05-04
EP0869808A1 (de)	1998-10-14
EP0869808B1 (de)	2006-07-12
CZ298345B6 (cs)	2007-09-05
NO981436L (no)	1998-05-19
KR100483779B1 (ko)	2007-03-02
MX9802564A (es)	1998-11-30
SK283677B6 (sk)	2003-11-04
BR9610838A (pt)	1999-12-21
DE69636343T2 (de)	2007-07-19
JPH11504943A (ja)	1999-05-11
US6911431B1 (en)	2005-06-28
HUP9902105A2 (hu)	1999-09-28
PL186123B1 (pl)	2003-10-31
NO981436D0 (no)	1998-03-30
ATE332702T1 (de)	2006-08-15
CA2233457A1 (en)	1997-04-10
CZ91398A3 (cs)	1998-11-11
SK42398A3 (en)	1998-10-07
US5902790A (en)	1999-05-11
US6096713A (en)	2000-08-01
KR19990063958A (ko)	1999-07-26
JP3679129B2 (ja)	2005-08-03
HUP9902105A3 (en)	2001-02-28
NZ319907A (en)	2000-09-29
ES2268710T3 (es)	2007-03-16
CN1198673A (zh)	1998-11-11
DE69636343D1 (de)	2006-08-24
WO1997012625A1 (en)	1997-04-10
CA2233457C (en)	2004-08-03
AU7254096A (en)	1997-04-28
AU714846B2 (en)	2000-01-13
CN1128636C (zh)	2003-11-26
EA001146B1 (ru)	2000-10-30

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