IE42340B1 - 11,12,-secoprostaglandins - Google Patents
11,12,-secoprostaglandinsInfo
- Publication number
- IE42340B1 IE42340B1 IE1925/75A IE192575A IE42340B1 IE 42340 B1 IE42340 B1 IE 42340B1 IE 1925/75 A IE1925/75 A IE 1925/75A IE 192575 A IE192575 A IE 192575A IE 42340 B1 IE42340 B1 IE 42340B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- hydroxy
- compounds
- pentyl
- fluorophenoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/505,445 US3991106A (en) | 1974-09-13 | 1974-09-13 | 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42340L IE42340L (en) | 1976-03-13 |
| IE42340B1 true IE42340B1 (en) | 1980-07-16 |
Family
ID=24010342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1925/75A IE42340B1 (en) | 1974-09-13 | 1975-09-03 | 11,12,-secoprostaglandins |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3991106A (nl) |
| JP (1) | JPS51125023A (nl) |
| BE (1) | BE833375A (nl) |
| DE (1) | DE2540736A1 (nl) |
| DK (1) | DK385475A (nl) |
| FR (1) | FR2284320A1 (nl) |
| GB (1) | GB1477280A (nl) |
| IE (1) | IE42340B1 (nl) |
| LU (1) | LU73389A1 (nl) |
| NL (1) | NL7510017A (nl) |
| SE (1) | SE7509519L (nl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091107A (en) * | 1973-04-25 | 1978-05-23 | Merck & Co., Inc. | 8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins |
| US4112236A (en) * | 1977-04-04 | 1978-09-05 | Merck & Co., Inc. | Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins |
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| UA59384C2 (uk) | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
| UA67754C2 (uk) | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
| AU1293101A (en) | 1999-12-22 | 2001-07-03 | Pfizer Products Inc. | Ep4 receptor selective agonists in the treatment of osteoporosis |
| PT1132086E (pt) | 2000-01-31 | 2006-09-29 | Pfizer Prod Inc | Utilizacao de agonistas selectivos para o receptor da prostaglandina (pge2) 4 (ep4) para o tratamento de falha renal aguda e cronica |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6858614B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| GB0610804D0 (en) * | 2006-05-31 | 2006-07-12 | Portela & Ca Sa | New crystal forms |
| JP2011506315A (ja) * | 2007-12-05 | 2011-03-03 | バイアル−ポルテラ アンド シーエー，エス．エー． | 新たな塩、及び結晶形 |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| CN108484513A (zh) | 2012-12-17 | 2018-09-04 | 帕里昂科学公司 | 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物 |
| EP2931712B8 (en) | 2012-12-17 | 2018-05-23 | Parion Sciences, Inc. | 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
| DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
-
1974
- 1974-09-13 US US05/505,445 patent/US3991106A/en not_active Expired - Lifetime
-
1975
- 1975-08-25 NL NL7510017A patent/NL7510017A/nl not_active Application Discontinuation
- 1975-08-27 SE SE7509519A patent/SE7509519L/xx unknown
- 1975-08-27 DK DK385475A patent/DK385475A/da unknown
- 1975-09-03 GB GB3631075A patent/GB1477280A/en not_active Expired
- 1975-09-03 IE IE1925/75A patent/IE42340B1/en unknown
- 1975-09-11 FR FR7527851A patent/FR2284320A1/fr active Granted
- 1975-09-12 BE BE160009A patent/BE833375A/xx unknown
- 1975-09-12 DE DE19752540736 patent/DE2540736A1/de not_active Withdrawn
- 1975-09-12 LU LU73389A patent/LU73389A1/xx unknown
- 1975-09-12 JP JP50110134A patent/JPS51125023A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE7509519L (sv) | 1976-03-15 |
| FR2284320A1 (fr) | 1976-04-09 |
| BE833375A (fr) | 1976-03-12 |
| NL7510017A (nl) | 1976-03-16 |
| JPS51125023A (en) | 1976-11-01 |
| FR2284320B1 (nl) | 1980-05-30 |
| IE42340L (en) | 1976-03-13 |
| DK385475A (da) | 1976-03-14 |
| GB1477280A (en) | 1977-06-22 |
| US3991106A (en) | 1976-11-09 |
| LU73389A1 (nl) | 1976-08-13 |
| DE2540736A1 (de) | 1976-03-25 |
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