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ID26031A - Turunan indol yang memiliki suatu aktivitas antiviral - Google Patents

Turunan indol yang memiliki suatu aktivitas antiviral

Info

Publication number
ID26031A
ID26031A IDW20001898A ID20001898A ID26031A ID 26031 A ID26031 A ID 26031A ID W20001898 A IDW20001898 A ID W20001898A ID 20001898 A ID20001898 A ID 20001898A ID 26031 A ID26031 A ID 26031A
Authority
ID
Indonesia
Prior art keywords
indol
damages
antiviral activity
antiviral
activity
Prior art date
Application number
IDW20001898A
Other languages
English (en)
Indonesian (id)
Inventor
Toshio Fujishita
Tomokazu Yoshinaga
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of ID26031A publication Critical patent/ID26031A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20001898A 1998-03-26 1999-03-26 Turunan indol yang memiliki suatu aktivitas antiviral ID26031A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7820398 1998-03-26

Publications (1)

Publication Number Publication Date
ID26031A true ID26031A (id) 2000-11-16

Family

ID=13655476

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001898A ID26031A (id) 1998-03-26 1999-03-26 Turunan indol yang memiliki suatu aktivitas antiviral

Country Status (17)

Country Link
US (3) US6333323B1 (zh)
EP (1) EP1069111A4 (zh)
JP (1) JP3794469B2 (zh)
KR (1) KR20010041705A (zh)
CN (1) CN1142909C (zh)
AU (1) AU752005B2 (zh)
BR (1) BR9909146A (zh)
CA (1) CA2326166A1 (zh)
HU (1) HUP0103460A3 (zh)
ID (1) ID26031A (zh)
IL (1) IL137974A0 (zh)
NO (1) NO317423B1 (zh)
NZ (1) NZ506435A (zh)
PL (1) PL343249A1 (zh)
RU (1) RU2217421C2 (zh)
WO (1) WO1999050245A1 (zh)
ZA (1) ZA200004047B (zh)

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US7294481B1 (en) * 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
KR100423781B1 (ko) * 1999-06-02 2004-03-22 시오노기세이야쿠가부시키가이샤 신규 치환 프로페논 유도체의 제조방법
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AU6731100A (en) * 1999-09-02 2001-04-10 Shionogi & Co., Ltd. Integrase inhibitors containing aromatic heterocycle derivatives
IL153363A0 (en) * 2000-06-13 2003-07-06 Shionogi & Co Pharmaceutical compositions containing propenone derivatives
AU2001262732A1 (en) * 2000-06-14 2001-12-24 Shionogi And Co., Ltd. Inhibitor for enzyme having two divalent metal ions as active centers
ES2402045T3 (es) * 2000-11-16 2013-04-26 The Regents Of The University Of California Taxón de actionomiceto marino para el descubrimiento de fármacos y de productos de fermentación
US7507767B2 (en) 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US7067539B2 (en) 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
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US20060063938A1 (en) * 2001-12-07 2006-03-23 Burke Terrence R Compounds to treat hiv infection and aids
US20030236277A1 (en) 2002-02-14 2003-12-25 Kadow John F. Indole, azaindole and related heterocyclic pyrrolidine derivatives
DE60319714T2 (de) 2002-06-19 2009-04-02 Schering Corp. Agonisten des cannabinoidrezeptors
US7176232B2 (en) 2002-06-24 2007-02-13 The Regents Of The University Of California Salinosporamides and methods for use thereof
US7935704B2 (en) * 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
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KR102680823B1 (ko) 2015-07-13 2024-07-03 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린 조성물
RU2753543C1 (ru) 2016-02-08 2021-08-17 Бейондспринг Фармасьютикалс, Инк. Композиции, содержащие тукаресол или его аналоги
IL263439B1 (en) 2016-06-06 2025-02-01 Beyondspring Pharmaceuticals Inc Composition and method for reducing neutropenia
JP2020503363A (ja) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド チューブリン結合化合物およびその治療的使用
KR20240110997A (ko) 2017-02-01 2024-07-16 비욘드스프링 파마수티컬스, 인코포레이티드. 호중구감소증의 감소 방법
CN106995400B (zh) * 2017-04-10 2019-08-06 湘潭大学 一种化合物及其盐及其合成方法
CN107226810B (zh) * 2017-06-16 2020-04-28 郑州大学 吲哚衍生物及其制备方法和其抗流感病毒作用
CN112135614A (zh) 2018-01-24 2020-12-25 大连万春布林医药有限公司 通过施用普那布林减少血小板减少症的组合物和方法
CN109810044B (zh) * 2019-02-27 2022-05-03 贵州医科大学 一种具有hiv-1整合酶抑制活性的化合物及其制备和应用
CN118451061A (zh) * 2021-12-20 2024-08-06 费尔黑文制药公司 Oxer1拮抗剂和其用途

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WO2001000578A1 (en) 1999-06-25 2001-01-04 Merck & Co., Inc. 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof

Also Published As

Publication number Publication date
AU752005B2 (en) 2002-09-05
IL137974A0 (en) 2001-10-31
BR9909146A (pt) 2000-12-05
ZA200004047B (en) 2001-04-25
NO20004787D0 (no) 2000-09-25
AU2958199A (en) 1999-10-18
EP1069111A1 (en) 2001-01-17
CN1294580A (zh) 2001-05-09
NO317423B1 (no) 2004-10-25
PL343249A1 (en) 2001-07-30
NZ506435A (en) 2002-08-28
CN1142909C (zh) 2004-03-24
NO20004787L (no) 2000-11-27
HUP0103460A2 (hu) 2002-01-28
US6716605B2 (en) 2004-04-06
CA2326166A1 (en) 1999-10-07
HUP0103460A3 (en) 2002-11-28
US6506787B2 (en) 2003-01-14
US20020019434A1 (en) 2002-02-14
EP1069111A4 (en) 2001-06-06
US6333323B1 (en) 2001-12-25
KR20010041705A (ko) 2001-05-25
WO1999050245A1 (fr) 1999-10-07
JP3794469B2 (ja) 2006-07-05
US20030181499A1 (en) 2003-09-25
RU2217421C2 (ru) 2003-11-27

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