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HUE039618T2 - Enzimvariánsok automatizált szûrése - Google Patents

Enzimvariánsok automatizált szûrése

Info

Publication number
HUE039618T2
HUE039618T2 HUE14781426A HUE14781426A HUE039618T2 HU E039618 T2 HUE039618 T2 HU E039618T2 HU E14781426 A HUE14781426 A HU E14781426A HU E14781426 A HUE14781426 A HU E14781426A HU E039618 T2 HUE039618 T2 HU E039618T2
Authority
HU
Hungary
Prior art keywords
enzyme variants
automated screening
screening
automated
variants
Prior art date
Application number
HUE14781426A
Other languages
English (en)
Inventor
Xiyun Zhang
Russell Javiniar Sarmiento
Donald Scott Baskerville
Gjait W Huisman
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of HUE039618T2 publication Critical patent/HUE039618T2/hu

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • G16C20/64—Screening of libraries

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Library & Information Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Computing Systems (AREA)
  • Analytical Chemistry (AREA)
  • Ecology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HUE14781426A 2013-09-27 2014-09-26 Enzimvariánsok automatizált szûrése HUE039618T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361883838P 2013-09-27 2013-09-27

Publications (1)

Publication Number Publication Date
HUE039618T2 true HUE039618T2 (hu) 2019-01-28

Family

ID=51662390

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE14781426A HUE039618T2 (hu) 2013-09-27 2014-09-26 Enzimvariánsok automatizált szûrése
HUE18187438A HUE053049T2 (hu) 2013-09-27 2014-09-26 Enzimvariánsok automatizált szûrése

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE18187438A HUE053049T2 (hu) 2013-09-27 2014-09-26 Enzimvariánsok automatizált szûrése

Country Status (15)

Country Link
US (3) US10696964B2 (hu)
EP (2) EP3049973B1 (hu)
JP (3) JP6857029B2 (hu)
KR (1) KR102342205B1 (hu)
CN (1) CN105765592B (hu)
AU (1) AU2014324669B2 (hu)
BR (1) BR112016006285B1 (hu)
CA (1) CA2923755C (hu)
DK (2) DK3049973T3 (hu)
ES (2) ES2857711T3 (hu)
HU (2) HUE039618T2 (hu)
IL (1) IL244457B (hu)
RU (2) RU2019140645A (hu)
SG (1) SG11201601695WA (hu)
WO (1) WO2015048572A1 (hu)

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CN111681703A (zh) * 2020-05-09 2020-09-18 北京纽伦智能科技有限公司 一种蛋白结构的对接方法及分布式蛋白结构对接系统
CN114822717A (zh) * 2021-01-28 2022-07-29 腾讯科技（深圳）有限公司 基于人工智能的药物分子处理方法、装置、设备及存储介质
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Also Published As

Publication number Publication date
JP2016537700A (ja) 2016-12-01
ES2693150T3 (es) 2018-12-07
JP2021131901A (ja) 2021-09-09
EP3418929B1 (en) 2020-12-09
CA2923755C (en) 2023-03-14
RU2016116253A (ru) 2017-11-01
EP3049973B1 (en) 2018-08-08
US20200277597A1 (en) 2020-09-03
IL244457B (en) 2021-05-31
KR102342205B1 (ko) 2021-12-21
CN105765592A (zh) 2016-07-13
RU2019140645A (ru) 2020-01-27
JP2019083025A (ja) 2019-05-30
US10696964B2 (en) 2020-06-30
US20230048421A1 (en) 2023-02-16
JP6857029B2 (ja) 2021-04-14
NZ717658A (en) 2020-11-27
AU2014324669A1 (en) 2016-03-24
AU2014324669B2 (en) 2020-06-04
EP3049973A1 (en) 2016-08-03
EP3418929A1 (en) 2018-12-26
CA2923755A1 (en) 2015-04-02
US11535845B2 (en) 2022-12-27
SG11201601695WA (en) 2016-04-28
KR20160057482A (ko) 2016-05-23
US20150133307A1 (en) 2015-05-14
BR112016006285B1 (pt) 2022-09-06
CN105765592B (zh) 2019-12-17
ES2857711T3 (es) 2021-09-29
DK3049973T3 (en) 2018-10-22
WO2015048572A1 (en) 2015-04-02
BR112016006285A2 (pt) 2017-08-01
HUE053049T2 (hu) 2021-06-28
IL244457A0 (en) 2016-04-21
DK3418929T3 (da) 2021-02-01

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