HUE055904T2 - 2-([1,2,3]triazol-2-il)-benzoesav-származékok elõállítása - Google Patents
2-([1,2,3]triazol-2-il)-benzoesav-származékok elõállításaInfo
- Publication number
- HUE055904T2 HUE055904T2 HUE18722948A HUE18722948A HUE055904T2 HU E055904 T2 HUE055904 T2 HU E055904T2 HU E18722948 A HUE18722948 A HU E18722948A HU E18722948 A HUE18722948 A HU E18722948A HU E055904 T2 HUE055904 T2 HU E055904T2
- Authority
- HU
- Hungary
- Prior art keywords
- triazol
- preparation
- benzoic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/72—Copper
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2017060451 | 2017-05-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE055904T2 true HUE055904T2 (hu) | 2021-12-28 |
Family
ID=62116854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18722948A HUE055904T2 (hu) | 2017-05-03 | 2018-05-02 | 2-([1,2,3]triazol-2-il)-benzoesav-származékok elõállítása |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11124488B2 (hu) |
| EP (1) | EP3619199B1 (hu) |
| JP (1) | JP7182562B2 (hu) |
| KR (1) | KR102582197B1 (hu) |
| CN (1) | CN110612291B (hu) |
| CA (1) | CA3059394C (hu) |
| CY (1) | CY1124777T1 (hu) |
| DK (1) | DK3619199T3 (hu) |
| ES (1) | ES2892161T3 (hu) |
| HR (1) | HRP20211304T1 (hu) |
| HU (1) | HUE055904T2 (hu) |
| IL (1) | IL270274B (hu) |
| LT (1) | LT3619199T (hu) |
| MX (1) | MX2019012902A (hu) |
| PL (1) | PL3619199T3 (hu) |
| PT (1) | PT3619199T (hu) |
| RS (1) | RS62357B1 (hu) |
| SI (1) | SI3619199T1 (hu) |
| TW (1) | TWI756418B (hu) |
| WO (1) | WO2018202689A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021213923A1 (en) | 2020-04-19 | 2021-10-28 | Idorsia Pharmaceuticals Ltd | Medical use of daridorexant |
| AR129309A1 (es) | 2022-05-13 | 2024-08-07 | Idorsia Pharmaceuticals Ltd | Derivados de hidrazina-n-carboxamida cíclica sustituida con tiazoloaril-metilo |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE500250T1 (de) | 2006-08-15 | 2011-03-15 | Actelion Pharmaceuticals Ltd | Azetidinverbindungen als orexin-rezeptor- antagonisten |
| CL2007002809A1 (es) | 2006-09-29 | 2008-04-18 | Actelion Pharmaceuticals Ltd | Compuestos derivados de 3-aza biciclo [3.1.0]hexano; y su uso en el tratamiento de enfermedades tales como desordenes psicoticos y de ansiedad, desordenes del sueno, uso y abuso de sustancias psicoactivas, demencia y deterioro de funciones cognitivas |
| PE20081229A1 (es) * | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
| AR064561A1 (es) | 2006-12-28 | 2009-04-08 | Actelion Pharmaceuticals Ltd | Derivados de 2-aza-biciclo[3.1.0]hexano y su uso en la preparacion de un medicamento para el tratamiento de enfermedades relacionadas con disfunciones generales del sistema de la orexina. |
| ES2351079T3 (es) | 2007-05-14 | 2011-01-31 | Actelion Pharmaceuticals Ltd. | Derivados de 2-ciclopropil-tiazol. |
| AU2008260647A1 (en) | 2007-05-23 | 2008-12-11 | Merck Sharp & Dohme Corp. | Cyclopropyl pyrrolidine orexin receptor antagonists |
| US9062044B2 (en) | 2009-10-23 | 2015-06-23 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
| DK3093291T3 (da) | 2009-10-23 | 2019-07-29 | Janssen Pharmaceutica Nv | Disubstituerede octahy-dropyrrolo [3,4-c]pyrroler som orexinreceptormodulatorer |
| JP5847087B2 (ja) * | 2009-10-23 | 2016-01-20 | ヤンセン ファーマシューティカ エヌ．ベー． | オレキシン受容体調節因子としての縮合複素環式化合物 |
| EP2653469A4 (en) | 2010-12-17 | 2014-05-07 | Taisho Pharmaceutical Co Ltd | pyrazole |
| WO2012085857A1 (en) | 2010-12-22 | 2012-06-28 | Actelion Pharmaceuticals Ltd | 3,8-diaza-bicyclo[4.2.0]oct-3-yl amides |
| US9108959B2 (en) | 2011-03-03 | 2015-08-18 | Merck Sharp & Dohme Corp. | Process for the preparation of an orexin receptor antagonist |
| US9586962B2 (en) | 2011-04-20 | 2017-03-07 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators |
| WO2013005755A1 (ja) | 2011-07-05 | 2013-01-10 | 大正製薬株式会社 | メチルピペリジン誘導体 |
| WO2013050938A1 (en) * | 2011-10-04 | 2013-04-11 | Actelion Pharmaceuticals Ltd | 3,7-diazabicyclo[3.3.1]nonane and 9-oxa-3,7-diazabicyclo[3.3.1]nonane derivatives |
| AU2012335194B2 (en) | 2011-11-08 | 2017-05-25 | Idorsia Pharmaceuticals Ltd | 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)picolinamide derivatives as orexin receptor antagonists |
| EP2847343A4 (en) | 2012-05-09 | 2016-04-06 | Merck Sharp & Dohme | METHOD FOR PREPARING AN INTERMEDIATE FOR AN OREXIN RECEPTOR ANTAGONIST |
| PL2855453T3 (pl) | 2012-06-04 | 2017-05-31 | Actelion Pharmaceuticals Ltd. | Pochodne benzimidazoloproliny |
| JP2014015452A (ja) | 2012-06-15 | 2014-01-30 | Taisho Pharmaceutical Co Ltd | ピラゾール誘導体を含有する医薬 |
| EP2906553B1 (en) | 2012-10-10 | 2019-06-26 | Idorsia Pharmaceuticals Ltd | Orexin receptor antagonists which are [ortho bi (hetero )aryl]-[2-(meta bi (hetero)aryl)-pyrrolidin-1-yl]-methanone derivatives |
| CA2902135A1 (en) | 2013-03-12 | 2014-09-18 | Actelion Pharmaceuticals Ltd | Azetidine amide derivatives as orexin receptor antagonists |
| TW201444849A (zh) * | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途 |
| TW201444821A (zh) | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代之哌啶化合物及其作為食慾素受體調節劑之用途 |
| AU2014358742B2 (en) * | 2013-12-03 | 2019-02-07 | Idorsia Pharmaceuticals Ltd | Crystalline form of (S)-(2-(6-chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1 -yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and its use as orexin receptor antagonists |
| UA119151C2 (uk) | 2013-12-03 | 2019-05-10 | Ідорсія Фармасьютікалз Лтд | КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА |
| EP3077391B1 (en) | 2013-12-04 | 2018-08-15 | Idorsia Pharmaceuticals Ltd | Use of benzimidazole-proline derivatives |
| WO2015123355A1 (en) * | 2014-02-12 | 2015-08-20 | Eolas Therapeutics, Inc. | Substituted prolines / piperidines as orexin receptor antagonists |
| WO2016020403A1 (en) | 2014-08-04 | 2016-02-11 | Sandoz Ag | Preparation of a benzoic acid derivative and its use for the preparation of suvorexant |
| CN104649983B (zh) * | 2014-12-23 | 2018-01-23 | 广东东阳光药业有限公司 | 一种酸的制备方法 |
| WO2016171248A1 (ja) * | 2015-04-24 | 2016-10-27 | 武田薬品工業株式会社 | 複素環化合物 |
-
2018
- 2018-05-02 DK DK18722948.9T patent/DK3619199T3/da active
- 2018-05-02 LT LTEPPCT/EP2018/061172T patent/LT3619199T/lt unknown
- 2018-05-02 CN CN201880028762.9A patent/CN110612291B/zh active Active
- 2018-05-02 TW TW107114814A patent/TWI756418B/zh active
- 2018-05-02 HU HUE18722948A patent/HUE055904T2/hu unknown
- 2018-05-02 JP JP2019559016A patent/JP7182562B2/ja active Active
- 2018-05-02 SI SI201830396T patent/SI3619199T1/sl unknown
- 2018-05-02 EP EP18722948.9A patent/EP3619199B1/en active Active
- 2018-05-02 PL PL18722948T patent/PL3619199T3/pl unknown
- 2018-05-02 ES ES18722948T patent/ES2892161T3/es active Active
- 2018-05-02 PT PT18722948T patent/PT3619199T/pt unknown
- 2018-05-02 US US16/610,413 patent/US11124488B2/en active Active
- 2018-05-02 MX MX2019012902A patent/MX2019012902A/es unknown
- 2018-05-02 WO PCT/EP2018/061172 patent/WO2018202689A1/en unknown
- 2018-05-02 CA CA3059394A patent/CA3059394C/en active Active
- 2018-05-02 IL IL270274A patent/IL270274B/en unknown
- 2018-05-02 KR KR1020197035319A patent/KR102582197B1/ko active IP Right Grant
- 2018-05-02 RS RS20211164A patent/RS62357B1/sr unknown
-
2021
- 2021-08-12 HR HRP20211304TT patent/HRP20211304T1/hr unknown
- 2021-10-06 CY CY20211100871T patent/CY1124777T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20210114997A1 (en) | 2021-04-22 |
| EP3619199B1 (en) | 2021-07-07 |
| PT3619199T (pt) | 2021-10-01 |
| JP7182562B2 (ja) | 2022-12-02 |
| LT3619199T (lt) | 2021-09-27 |
| ES2892161T3 (es) | 2022-02-02 |
| TW201843144A (zh) | 2018-12-16 |
| JP2020518573A (ja) | 2020-06-25 |
| WO2018202689A1 (en) | 2018-11-08 |
| DK3619199T3 (da) | 2021-09-27 |
| MX2019012902A (es) | 2019-12-16 |
| KR102582197B1 (ko) | 2023-09-22 |
| KR20200003097A (ko) | 2020-01-08 |
| CA3059394A1 (en) | 2018-11-08 |
| US11124488B2 (en) | 2021-09-21 |
| RS62357B1 (sr) | 2021-10-29 |
| HRP20211304T1 (hr) | 2021-11-12 |
| CN110612291A (zh) | 2019-12-24 |
| IL270274B (en) | 2022-08-01 |
| CN110612291B (zh) | 2024-02-13 |
| IL270274A (hu) | 2019-12-31 |
| PL3619199T3 (pl) | 2021-12-20 |
| EP3619199A1 (en) | 2020-03-11 |
| CY1124777T1 (el) | 2022-11-25 |
| TWI756418B (zh) | 2022-03-01 |
| SI3619199T1 (sl) | 2021-11-30 |
| CA3059394C (en) | 2023-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3402787A4 (en) | PROCESSES FOR PREPARING 2,5-FURANDICARBOXYLIC ACID AND INTERMEDIATES AND DERIVATIVES THEREOF | |
| HUE065368T2 (hu) | Eljárás 2,5-furándikabonsav és származékai elõállítására | |
| HK1254055A1 (zh) | 製備奧貝膽酸及其衍生物的方法 | |
| EP3679945A4 (en) | AQUEOUS PHARMACEUTICAL COMPOSITION | |
| EP3480198A4 (en) | NEW COMPOUND OR ITS PHARMACEUTICALLY ACCEPTED SALT | |
| IL271399A (en) | Methods for the preparation of heterocyclic 3,1-benzodioxole compounds | |
| IL260011B (en) | History of water-soluble 5,3-diphenyldiazole compounds | |
| HK1256825A1 (zh) | 取代的5，6-二氫-6-苯基苯並[f]異喹啉-2-胺化合物的固體形式 | |
| MX2020012771A (es) | Metodos para preparar 5,6-dihidro-6-fenilbenzo[f]isoquinolin-2-ami na sustituida. | |
| IL262405A (en) | Methods for the preparation of obeticholic acid and derivatives thereof | |
| PT3619199T (pt) | Preparação de derivados de ácido 2-([1,2,3]triazol-2-il)- benzoico | |
| IL254578A0 (en) | Abscisic acid (s)-2' vinyl derivatives | |
| EP3530654A4 (en) | CARBOXYLIC ACID COMPOUND WITH QUINOLINYL SUBSTITUTE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | |
| EP3189842A4 (en) | Composition for preventing hair loss or promoting hair growth, containing oleanolic acid derivative and pharmaceutically acceptable salt thereof | |
| HK1258757A1 (zh) | 4H-吡唑並[1，5-α]苯並咪唑類化合物的鹽型、晶型及其製備方法和中間體 | |
| EP3699250A4 (en) | COMPOSITION PROVIDING A FRESHNESS FEELING CONTAINING A DERIVATIVE OF 2,2,6-TRIMETHYLCYLCYCLOHEXANECARBOXYLIC ACID | |
| EP3398946A4 (en) | SALT OF MORPHOLINE DERIVATIVE AND ITS CRYSTALLINE FORM, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | |
| IL249519B (en) | History of abscisic acid - converted at the 3' position | |
| EP3856732C0 (en) | PROCESS AND SALTS FOR THE PREPARATION OF 2,5-FURANEDICARBOXYLIC ACID | |
| EP3177592A4 (en) | Process for the preparation of 4,5,6-trichloropicolinic acid | |
| EP3592735A4 (en) | IMPROVED PROCESS FOR THE PREPARATION OF TETROFOSMINE OR AN ACID ADDITION SALT THEREOF | |
| HUP1500451A2 (en) | Processes for the preparation of 1,4,7-triaza-cyclononane derivatives and intermediates |