HRP990408B1 - Process for preparing enantiomerically enriched n-derivatised lactams - Google Patents

Process for preparing enantiomerically enriched n-derivatised lactams

Info

Publication number: HRP990408B1
Authority: HR; Croatia
Prior art keywords: derivatised; lactams; enantiomerically enriched; preparing enantiomerically; azabicyclo
Prior art date: 1997-08-22

Application number

HR990408A

Other languages

English (en)

Croatian (hr)

Inventor

John Dawson Michael

Mahmoudian Mahmoud

John Wallis Christopher

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-22

Filing date

1999-12-23

Publication date

2006-05-31

1999-12-23 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2000-04-30 Publication of HRP990408A2 publication Critical patent/HRP990408A2/hr

2006-05-31 Publication of HRP990408B1 publication Critical patent/HRP990408B1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HR990408A 1997-08-22 1999-12-23 Process for preparing enantiomerically enriched n-derivatised lactams HRP990408B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9717928.7A GB9717928D0 (en)	1997-08-22	1997-08-22	Process for the enatioselective hydrolysis of n-derivatised lactams

Publications (2)

Publication Number	Publication Date
HRP990408A2 HRP990408A2 (en)	2000-04-30
HRP990408B1 true HRP990408B1 (en)	2006-05-31

Family

ID=10817952

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR990408A HRP990408B1 (en)	1997-08-22	1999-12-23	Process for preparing enantiomerically enriched n-derivatised lactams

Country Status (35)

Country	Link
US (1)	US6340587B1 (hu)
EP (1)	EP1003903B1 (hu)
JP (1)	JP3565868B2 (hu)
KR (1)	KR100479894B1 (hu)
CN (1)	CN1133749C (hu)
AP (1)	AP1104A (hu)
AR (1)	AR016395A1 (hu)
AT (1)	ATE233323T1 (hu)
AU (1)	AU738897B2 (hu)
BR (1)	BR9810472B1 (hu)
CA (1)	CA2295017A1 (hu)
CZ (1)	CZ294302B6 (hu)
DE (1)	DE69811677T2 (hu)
DK (1)	DK1003903T3 (hu)
EA (1)	EA001964B1 (hu)
EE (1)	EE03934B1 (hu)
ES (1)	ES2193568T3 (hu)
GB (1)	GB9717928D0 (hu)
HK (1)	HK1025796A1 (hu)
HR (1)	HRP990408B1 (hu)
HU (1)	HU222657B1 (hu)
ID (1)	ID25830A (hu)
IL (1)	IL133541A (hu)
IN (1)	IN183908B (hu)
IS (1)	IS2201B (hu)
NO (1)	NO320081B1 (hu)
NZ (1)	NZ501880A (hu)
PL (1)	PL191108B1 (hu)
PT (1)	PT1003903E (hu)
RS (1)	RS49542B (hu)
SI (1)	SI1003903T1 (hu)
SK (1)	SK282782B6 (hu)
TR (1)	TR199903210T2 (hu)
TW (1)	TW589301B (hu)
WO (1)	WO1999010519A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6780634B1 (en)	1998-07-09	2004-08-24	Lonza Ag	Method for producing (1R,4S)-2-azabicyclo[2.2.1]-hept-5-en-3-on derivatives
DE19962543A1 (de)	1999-12-23	2001-07-05	Degussa	Chromatographische Enantiomerentrennung von bicyclischen Lactamen
US6780635B2 (en)	2001-12-27	2004-08-24	Council Of Scientific And Industrial Research	Process for the preparation of optically active azabicyclo heptanone derivatives
DE60211646T2 (de) *	2002-03-28	2007-05-24	Council Of Scientific And Industrial Research	Verfahren zur Herstellung von optisch aktiven Azabicycloheptanone-Derivaten
HU227663B1 (en) *	2007-07-09	2011-10-28	Univ Szegedi	Resolution process
EP3494972B1 (en)	2010-01-27	2023-12-13	VIIV Healthcare Company	Combinations of dolutegravir and lamivudine for the treatment of hiv infection
CN103695495B (zh) *	2014-01-14	2014-08-27	营口三征新科技化工有限公司	一种制备(1R,4s)-(-)-2-氮杂双环[2,2,1]庚-5-烯-3-酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0424064T3 (da) *	1989-10-16	1995-06-26	Chiroscience Ltd	Chirale azabicycloheptanoner og fremgangsmåde til fremstilling deraf
GB9108384D0 (en) *	1991-04-19	1991-06-05	Enzymatix Ltd	Bicycloheptanes
SK285228B6 (sk) *	1997-05-13	2006-09-07	Lonza Ag	Spôsob výroby racemického alebo opticky aktívnehoderivátu 4-(hydroxymetyl)-2-cyklopenténu a racemicky N-butyryl-1-amino-4- (hydroxymetyl)-2-cyklopentén

1997
- 1997-08-22 GB GBGB9717928.7A patent/GB9717928D0/en active Pending
1998
- 1998-08-20 PT PT98951307T patent/PT1003903E/pt unknown
- 1998-08-20 CA CA002295017A patent/CA2295017A1/en not_active Abandoned
- 1998-08-20 KR KR10-1999-7012114A patent/KR100479894B1/ko not_active IP Right Cessation
- 1998-08-20 RS YUP-693/99A patent/RS49542B/sr unknown
- 1998-08-20 CN CNB988064790A patent/CN1133749C/zh not_active Expired - Lifetime
- 1998-08-20 AU AU97386/98A patent/AU738897B2/en not_active Expired
- 1998-08-20 PL PL337647A patent/PL191108B1/pl unknown
- 1998-08-20 TW TW087113730A patent/TW589301B/zh not_active IP Right Cessation
- 1998-08-20 EP EP98951307A patent/EP1003903B1/en not_active Expired - Lifetime
- 1998-08-20 HU HU0002661A patent/HU222657B1/hu active IP Right Grant
- 1998-08-20 AT AT98951307T patent/ATE233323T1/de active
- 1998-08-20 DK DK98951307T patent/DK1003903T3/da active
- 1998-08-20 BR BRPI9810472-1A patent/BR9810472B1/pt not_active IP Right Cessation
- 1998-08-20 NZ NZ501880A patent/NZ501880A/en not_active IP Right Cessation
- 1998-08-20 SI SI9830407T patent/SI1003903T1/xx unknown
- 1998-08-20 US US09/446,587 patent/US6340587B1/en not_active Expired - Lifetime
- 1998-08-20 DE DE69811677T patent/DE69811677T2/de not_active Expired - Lifetime
- 1998-08-20 AP APAP/P/1999/001721A patent/AP1104A/en active
- 1998-08-20 SK SK1844-99A patent/SK282782B6/sk not_active IP Right Cessation
- 1998-08-20 WO PCT/EP1998/005291 patent/WO1999010519A1/en active IP Right Grant
- 1998-08-20 CZ CZ19994716A patent/CZ294302B6/cs not_active IP Right Cessation
- 1998-08-20 EE EEP200000075A patent/EE03934B1/xx unknown
- 1998-08-20 JP JP51391699A patent/JP3565868B2/ja not_active Expired - Lifetime
- 1998-08-20 EA EA199901059A patent/EA001964B1/ru not_active IP Right Cessation
- 1998-08-20 TR TR1999/03210T patent/TR199903210T2/xx unknown
- 1998-08-20 ID IDW991671A patent/ID25830A/id unknown
- 1998-08-20 IL IL13354198A patent/IL133541A/xx not_active IP Right Cessation
- 1998-08-20 ES ES98951307T patent/ES2193568T3/es not_active Expired - Lifetime
- 1998-08-21 AR ARP980104167A patent/AR016395A1/es active IP Right Grant
- 1998-08-21 IN IN1499CA1998 patent/IN183908B/en unknown
1999
- 1999-12-14 IS IS5297A patent/IS2201B/is unknown
- 1999-12-21 NO NO19996368A patent/NO320081B1/no not_active IP Right Cessation
- 1999-12-23 HR HR990408A patent/HRP990408B1/xx not_active IP Right Cessation
2000
- 2000-08-09 HK HK00104972A patent/HK1025796A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20010014078A (ko)	2001-02-26
DK1003903T3 (da)	2003-06-10
CN1261405A (zh)	2000-07-26
CZ294302B6 (cs)	2004-11-10
ES2193568T3 (es)	2003-11-01
WO1999010519A1 (en)	1999-03-04
AU738897B2 (en)	2001-09-27
SK184499A3 (en)	2000-09-12
IS2201B (is)	2007-02-15
NO996368L (no)	2000-02-21
JP3565868B2 (ja)	2004-09-15
NO320081B1 (no)	2005-10-17
HRP990408A2 (en)	2000-04-30
HU222657B1 (hu)	2003-09-29
IS5297A (is)	1999-12-14
GB9717928D0 (en)	1997-10-29
HUP0002661A2 (hu)	2000-12-28
CA2295017A1 (en)	1999-03-04
EP1003903B1 (en)	2003-02-26
EA199901059A1 (ru)	2000-08-28
YU69399A (sh)	2002-06-19
EA001964B1 (ru)	2001-10-22
IL133541A (en)	2003-10-31
PL191108B1 (pl)	2006-03-31
CN1133749C (zh)	2004-01-07
AP9901721A0 (en)	1999-12-31
BR9810472A (pt)	2000-09-19
PT1003903E (pt)	2003-06-30
DE69811677D1 (de)	2003-04-03
SK282782B6 (sk)	2002-12-03
EE03934B1 (et)	2002-12-16
JP2001504354A (ja)	2001-04-03
HK1025796A1 (en)	2000-11-24
IN183908B (hu)	2000-05-13
NZ501880A (en)	2001-08-31
BR9810472B1 (pt)	2011-01-11
HUP0002661A3 (en)	2001-12-28
AP1104A (en)	2002-09-04
DE69811677T2 (de)	2003-10-16
ATE233323T1 (de)	2003-03-15
RS49542B (sr)	2007-02-05
TR199903210T2 (xx)	2000-07-21
SI1003903T1 (en)	2003-08-31
KR100479894B1 (ko)	2005-03-30
IL133541A0 (en)	2001-04-30
CZ471699A3 (cs)	2000-06-14
EE200000075A (et)	2000-10-16
AR016395A1 (es)	2001-07-04
EP1003903A1 (en)	2000-05-31
US6340587B1 (en)	2002-01-22
PL337647A1 (en)	2000-08-28
TW589301B (en)	2004-06-01
NO996368D0 (no)	1999-12-21
AU9738698A (en)	1999-03-16
ID25830A (id)	2000-11-09

Publication	Publication Date	Title
HU9501329D0 (en)	1995-06-28	Novel 3,3-diphenylpropylamines, their use and preparation
TW341565B (en)	1998-10-01	Indole derivatives processes and intermediates for their preparation and pharmaceutical compositions containing them
AU6208990A (en)	1991-03-14	N-substituted-4-pyrimidinamines and pyrimidindiamines, a process for their preparation and their use as medicaments
CA2174000A1 (en)	1995-04-27	Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane
IE883463L (en)	1989-05-20	3-£4(1-Substituted-4-piperazinyl)butyl\|-4-thiazolidinones, a process for their preparation and their use as medicaments
ES8203872A1 (es)	1982-04-01	Un procedimiento para la preparacion de espiro (ciclohexano-1,1'(3'h)-isobenzoeuranos)
HRP990408B1 (en)	2006-05-31	Process for preparing enantiomerically enriched n-derivatised lactams
AU3170597A (en)	1998-01-05	Process for the preparation of amino alcohols and derivatives thereof
CA2031756A1 (en)	1991-06-12	Isatine derivatives, their preparation and use
AU6851396A (en)	1997-03-12	Novel fused isoquinolines as dopamine receptor ligands
PT85869A (en)	1987-11-01	Process for preparing amino acid derivative anti-convulsant
ES8801673A1 (es)	1988-02-16	Un procedimiento para la preparacion de derivados peptidicos de histidinilprolinamida.
DK0925361T3 (da)	2010-04-12	Mikroorganisme, derfra opnået lactamasenzym, og anvendelse deraf
GB9707413D0 (en)	1997-05-28	Process
NZ217813A (en)	1991-01-29	Dipeptides and process for their preparation using an enzyme coupling agent
WO2000048549A3 (en)	2002-04-04	Anticonvulsant derivatives useful in treating essential tremor
ES2000405A6 (es)	1988-02-16	Procedimiento para la preparacion de cotarnina
HU913759D0 (en)	1992-02-28	Process for the production of indole compounds
SG47459A1 (en)	1998-04-17	Process for preparing enantiomerically pure imidazo(4,5,1)(1,4)benzodiazepin-2(1H)-thiones
EP0167922A3 (en)	1987-01-21	Pyrrolo û1,2-b¨ û1,2,5¨ triazepines, a process and intermediates for their preparation and their use as medicaments
AU3481395A (en)	1996-03-29	Ring-opening amidation process
JPS5750958A (en)	1982-03-25	Preparation of tryptophan derivative
TH57841A (th)	2003-08-25	กรรมวิธีไฮโดรไลซิสที่เลือกจำเพาะต่ออีแนนทิโอเมอร์ของ n-เดริเวไทซ์แลกแทม
DE50009160D1 (de)	2005-02-10	Verfahren zur herstellung von optisch aktiven 3,3,3- trifluormethyl- 2- alkylpropionsäurederivaten
EP1197489A4 (en)	2002-09-25	PYRIMIDINE DERIVATIVES AND THEIR PREPARATION PROCESS

Legal Events

Date	Code	Title	Description
2000-04-30	A1OB	Publication of a patent application
2000-08-11	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2006-05-31	B1PR	Patent granted
2017-08-03	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20170803 Year of fee payment: 20
2018-08-27	PB20	Patent expired after termination of 20 years	Effective date: 20180820