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HN2011000404A - Derivados de enfumafungina y composicion comprendiendo los mismos - Google Patents

Derivados de enfumafungina y composicion comprendiendo los mismos

Info

Publication number
HN2011000404A
HN2011000404A HN2011000404A HN2011000404A HN2011000404A HN 2011000404 A HN2011000404 A HN 2011000404A HN 2011000404 A HN2011000404 A HN 2011000404A HN 2011000404 A HN2011000404 A HN 2011000404A HN 2011000404 A HN2011000404 A HN 2011000404A
Authority
HN
Honduras
Prior art keywords
compounds
enfumafungina
understanding
same
derivatives
Prior art date
Application number
HN2011000404A
Other languages
English (en)
Inventor
L Greenlee Mark
Wilkening Robert
Apgar James
James Wildonger Kenneth
Meng Dongfang
L Jr Parker Dann
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41669132&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HN2011000404(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of HN2011000404A publication Critical patent/HN2011000404A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Agronomy & Crop Science (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NOVEDOSOS DERIVADOS DE ENFUMAFUNGINA, JUNTO CON SUS SALES, HIDRATOS Y PORDROGAS FARMACEUTICAMENTE ACEPTABLES. TAMBIEN SE DESCRIBEN COMPOSICIONES QUE COMPRENDEN DICHOS COMPUESTOS, METODOS PARA PREPARAR DICHOS COMPUESTOS Y METODOS PARA USAR DICHOS COMPUESTOS COMO AGENTES ANTIFUNGICOS Y/O INHIBIDORES DE (1,3)-b-D-glucan SINTASA. LOS COMPUESTOS DESCRIPTOS, SUS SALES HIDRATOS Y PRODROGAS FARMACEUTICAMENTE ACEPTABLES, ASI COMO LAS COMPOSICIONES QUE COMPRENDEN DICHAS SALES, HIDRATOS Y PRODROGAS, SON UTILES PARA TRATAR Y/O PREVENIR INFECCIONES FUNGICAS Y ENFERMEDADES Y AFECCIONES ASOCIADAS.
HN2011000404A 2008-08-12 2011-02-11 Derivados de enfumafungina y composicion comprendiendo los mismos HN2011000404A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13610608P 2008-08-12 2008-08-12

Publications (1)

Publication Number Publication Date
HN2011000404A true HN2011000404A (es) 2013-09-23

Family

ID=41669132

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2011000404A HN2011000404A (es) 2008-08-12 2011-02-11 Derivados de enfumafungina y composicion comprendiendo los mismos

Country Status (31)

Country Link
EP (1) EP2326172B1 (es)
KR (1) KR101686075B1 (es)
AR (1) AR073037A1 (es)
BR (1) BRPI0912074B1 (es)
CL (1) CL2011000292A1 (es)
CO (1) CO6351686A2 (es)
CR (1) CR20110075A (es)
DK (1) DK2326172T3 (es)
DO (1) DOP2011000053A (es)
EA (1) EA018337B1 (es)
ES (1) ES2526652T3 (es)
GT (1) GT201100039A (es)
HK (1) HK1158017A1 (es)
HN (1) HN2011000404A (es)
HR (1) HRP20150009T1 (es)
IL (2) IL210975A (es)
MA (1) MA32628B1 (es)
MX (1) MX2011001656A (es)
MY (1) MY156955A (es)
NI (1) NI201100035A (es)
NZ (1) NZ590914A (es)
PE (1) PE20110676A1 (es)
PL (1) PL2326172T3 (es)
PT (1) PT2326172E (es)
RS (1) RS53731B1 (es)
SI (1) SI2326172T1 (es)
SV (1) SV2011003839A (es)
TW (1) TWI439458B (es)
UA (1) UA105639C2 (es)
WO (1) WO2010019203A1 (es)
ZA (1) ZA201100788B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20220544T1 (hr) * 2015-01-19 2022-08-05 Scynexis, Inc. Nove soli i polimorfi scy-078
JP7263313B2 (ja) * 2017-04-10 2023-04-24 サイネクシス，インコーポレーテッド 併用される抗真菌剤
JP7214714B2 (ja) * 2017-08-04 2023-01-30 サイネクシス，インコーポレーテッド 酸性ｐＨで活性の増強を示す抗真菌剤
MA54866A (fr) * 2019-01-30 2022-05-04 Scynexis Inc Antifongiques triterpénoïdes pour le traitement d'infections ostéoarticulaires fongiques
CA3140637A1 (en) * 2019-05-16 2020-11-19 Scynexis, Inc. Antifungal agents, like ibrexafungerp for candida auris decolonization
EP4157356A1 (en) 2020-05-29 2023-04-05 Centre National de la Recherche Scientifique Antifungal prodrugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756472A (en) 1996-01-31 1998-05-26 Merck & Co., Inc. Antifungal agent obtained from hormonema
WO1997027860A1 (en) * 1996-01-31 1997-08-07 Merck & Co., Inc. Antifungal agent
CN1705657A (zh) * 2002-04-17 2005-12-07 兰贝克赛实验室有限公司 作为抗真菌剂的吡咯衍生物
EP2007396B1 (en) 2006-04-03 2013-02-13 Merck Sharp & Dohme Corp. Enfumafungin derivatives as antifungal agents

Also Published As

Publication number Publication date
TW201011004A (en) 2010-03-16
MY156955A (en) 2016-04-15
BRPI0912074A2 (pt) 2018-10-02
IL242031A0 (en) 2015-11-30
NI201100035A (es) 2011-09-20
EP2326172B1 (en) 2014-10-22
MA32628B1 (fr) 2011-09-01
NZ590914A (en) 2011-11-25
PT2326172E (pt) 2015-02-04
EA201100350A1 (ru) 2011-08-30
HRP20150009T1 (hr) 2015-02-27
IL210975A (en) 2015-10-29
AR073037A1 (es) 2010-10-06
PL2326172T3 (pl) 2015-03-31
DOP2011000053A (es) 2011-04-30
UA105639C2 (uk) 2014-06-10
MX2011001656A (es) 2011-05-25
SV2011003839A (es) 2011-07-06
RS53731B1 (en) 2015-06-30
ES2526652T3 (es) 2015-01-14
EA018337B1 (ru) 2013-07-30
KR101686075B1 (ko) 2016-12-13
PE20110676A1 (es) 2011-09-23
HK1158017A1 (en) 2012-07-13
EP2326172A4 (en) 2012-06-06
IL210975A0 (en) 2011-04-28
BRPI0912074B1 (pt) 2021-08-03
WO2010019203A8 (en) 2011-03-17
GT201100039A (es) 2013-08-21
DK2326172T3 (da) 2015-01-26
EP2326172A1 (en) 2011-06-01
TWI439458B (zh) 2014-06-01
CR20110075A (es) 2011-06-03
SI2326172T1 (sl) 2015-02-27
CO6351686A2 (es) 2011-12-20
WO2010019203A1 (en) 2010-02-18
CL2011000292A1 (es) 2011-11-04
ZA201100788B (en) 2012-05-01
KR20110045054A (ko) 2011-05-03

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