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HK94390A - Pharmaceutical compositions containing anthracycline glycosides - Google Patents

Pharmaceutical compositions containing anthracycline glycosides

Info

Publication number
HK94390A
HK94390A HK943/90A HK94390A HK94390A HK 94390 A HK94390 A HK 94390A HK 943/90 A HK943/90 A HK 943/90A HK 94390 A HK94390 A HK 94390A HK 94390 A HK94390 A HK 94390A
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical compositions
compositions containing
anthracycline glycosides
containing anthracycline
glycosides
Prior art date
Application number
HK943/90A
Other languages
English (en)
Inventor
Gaetano Gatti
Diego Oldani
Carlo Confalonieri
Luciano Gambini
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of HK94390A publication Critical patent/HK94390A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK943/90A 1984-10-22 1990-11-15 Pharmaceutical compositions containing anthracycline glycosides HK94390A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848426672A GB8426672D0 (en) 1984-10-22 1984-10-22 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
HK94390A true HK94390A (en) 1990-11-23

Family

ID=10568553

Family Applications (1)

Application Number Title Priority Date Filing Date
HK943/90A HK94390A (en) 1984-10-22 1990-11-15 Pharmaceutical compositions containing anthracycline glycosides

Country Status (35)

Country Link
US (4) US4675311A (de)
JP (1) JPH0611700B2 (de)
KR (1) KR920005813B1 (de)
CN (1) CN85107562B (de)
AT (1) AT401345B (de)
AU (1) AU572003B2 (de)
BE (1) BE903484A (de)
BG (1) BG60934B2 (de)
CA (1) CA1248453A (de)
CH (1) CH667594A5 (de)
CS (1) CS270421B2 (de)
DE (1) DE3536896C2 (de)
DK (1) DK165620C (de)
ES (1) ES8605374A1 (de)
FI (2) FI853913A (de)
FR (1) FR2571966B1 (de)
GB (2) GB8426672D0 (de)
GR (1) GR852549B (de)
HK (1) HK94390A (de)
HU (1) HU197988B (de)
IE (1) IE56992B1 (de)
IL (1) IL76732A (de)
IT (1) IT1186779B (de)
MY (1) MY103956A (de)
NL (1) NL191308C (de)
NO (1) NO170616C (de)
NZ (1) NZ213885A (de)
PH (1) PH23982A (de)
PT (1) PT81347B (de)
RU (2) RU1836088C (de)
SE (1) SE467520B (de)
SG (1) SG80290G (de)
UA (2) UA34419C2 (de)
YU (1) YU46160B (de)
ZA (1) ZA858033B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NL8702914A (nl) * 1986-12-05 1988-07-01 Erba Farmitalia Injecteerbare, voor gebruik gerede oplossingen, die een antracyclineglycoside als antitumormiddel bevatten alsmede werkwijze voor de bereiding daarvan.
JP2603480B2 (ja) * 1987-08-05 1997-04-23 住友製薬株式会社 安定化されたアンスラサイクリン系製剤
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
US6300362B1 (en) 1990-07-25 2001-10-09 Novartis Ag (Formerly Sandoz Ltd.) Stabilized pharmaceutical compositions comprising acid donors
CA2628857C (en) 1996-12-30 2011-09-13 Batelle Memorial Institute Formulation and method for treating neoplasms by inhalation
US5942508A (en) * 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
WO2003072082A1 (en) 2002-02-22 2003-09-04 Schering Corporation Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same
EP1474995B1 (de) * 2003-05-06 2012-11-14 Gumlink A/S Methode zu Herstellung von Kaugummigranulat, ein Kaugummiextruder mit Granuliersystem und ein Kaugummiprodukt
US20090099346A1 (en) * 2003-07-02 2009-04-16 Victor Matvienko Thermally stable crystalline epirubicin hydrochloride
ATE520702T1 (de) * 2003-07-02 2011-09-15 Solux Corp Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür
ATE471740T1 (de) * 2003-09-25 2010-07-15 Astellas Pharma Inc Antitumorales mittel mit einem histon-deacetylase-hemmer und einem topoisomerase-ii-hemmer
US7388083B2 (en) * 2005-03-07 2008-06-17 Solux Corporation Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
EP1814525A2 (de) * 2005-05-11 2007-08-08 Sicor Inc. Stabile lyophilisierte anthracyclin-glycoside
WO2007011743A2 (en) 2005-07-14 2007-01-25 Lipothera, Inc. Sustained release enhanced lipolytic formulation for regional adipose tissue treatment
DE06848583T1 (de) * 2005-12-13 2011-03-17 Solux Corporation, San Diego Verfahren zur herstellung von 4-demethyldaunorubicin
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8148338B2 (en) * 2006-02-22 2012-04-03 Supratek Pharma Inc. Doxorubicin formulations for anti-cancer use
US7470672B2 (en) * 2006-07-31 2008-12-30 Savvipharm Inc. Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives
EP2152312B1 (de) * 2007-05-16 2014-12-31 KTB Tumorforschungsgesellschaft mbH Niedrigviskose anthracyclinformulierung
BRPI0816364B8 (pt) 2007-09-04 2021-05-25 Meiji Seika Kaisha solução de injeção, preparação de kit de injeção e injetável para preparar solução de injeção
BRPI0818860A2 (pt) * 2007-10-26 2015-04-22 Pfizer Prod Inc Idarubicina para o tratamento de linfoma em um cão
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
AU2011205646B2 (en) * 2010-01-15 2014-10-02 Neothetics, Inc. Lyophilized cake formulations
KR20140025312A (ko) 2010-11-24 2014-03-04 리쎄라 인코오포레이티드 지방증 및 윤곽 팽창의 미용적 치료를 위한 선택적인, 친유성, 및 지속성 베타 작용제 단일치료 제형 및 방법
DE102011103751A1 (de) 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid
DE102011111991A1 (de) * 2011-08-30 2013-02-28 Lead Discovery Center Gmbh Neue Cyclosporin-Derivate
AU2013359048A1 (en) 2012-12-13 2015-07-02 Cytrx Corporation Anthracycline formulations
JP2016521705A (ja) 2013-06-05 2016-07-25 サイトレックス コーポレイション がんを処置するための細胞傷害剤

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1567456A (en) * 1976-11-16 1980-05-14 Farmaceutici Italia Daunomycin derivatives
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
JPS563851A (en) * 1979-06-22 1981-01-16 Matsushita Electric Works Ltd Fireplace in floor
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
US4325947A (en) * 1981-05-12 1982-04-20 Farmitalia Carlo Erba S.P.A. 4-Demethoxy-4'-deoxydoxorubicin
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
AT380480B (de) * 1982-05-24 1986-05-26 Erba Farmitalia Verfahren zur herstellung von anthracyclinglykosiden
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
JPS5982395A (ja) * 1982-11-02 1984-05-12 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
GR79729B (de) * 1982-12-20 1984-10-31 Univ Ohio State Res Found
JPS6092212A (ja) * 1983-10-26 1985-05-23 Kyowa Hakko Kogyo Co Ltd ドキソルビシン塩の製剤
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

Also Published As

Publication number Publication date
RU1836088C (ru) 1993-08-23
US5091372A (en) 1992-02-25
US4840938A (en) 1989-06-20
NO170616C (no) 1992-11-11
FI854035L (fi) 1986-04-23
NL191308B (nl) 1994-12-16
IE852593L (en) 1986-04-22
GB2165751B (en) 1988-08-17
AU572003B2 (en) 1988-04-28
IE56992B1 (en) 1992-02-26
US5091373A (en) 1992-02-25
US4675311A (en) 1987-06-23
DE3536896C2 (de) 1996-11-14
CN85107562B (zh) 1988-06-01
JPH0611700B2 (ja) 1994-02-16
CS756585A2 (en) 1989-11-14
HUT40759A (en) 1987-02-27
NL8502869A (nl) 1986-05-16
KR920005813B1 (ko) 1992-07-20
IL76732A0 (en) 1986-02-28
ES8605374A1 (es) 1986-03-16
DK481585A (da) 1986-04-23
FI853913A (fi) 1986-04-23
GB8525709D0 (en) 1985-11-20
NO854194L (no) 1986-04-23
YU164485A (en) 1987-10-31
HU197988B (en) 1989-07-28
GR852549B (de) 1986-02-24
FI854035A0 (fi) 1985-10-16
NZ213885A (en) 1988-05-30
AT401345B (de) 1996-08-26
MY103956A (en) 1993-10-30
ES547578A0 (es) 1986-03-16
UA34419C2 (uk) 2001-03-15
IL76732A (en) 1989-07-31
UA19169A (uk) 1997-12-25
SE467520B (sv) 1992-08-03
DK481585D0 (da) 1985-10-21
ZA858033B (en) 1986-06-25
YU46160B (sh) 1993-05-28
FR2571966A1 (fr) 1986-04-25
DK165620C (da) 1993-06-01
FR2571966B1 (fr) 1988-04-15
CA1248453A (en) 1989-01-10
IT1186779B (it) 1987-12-16
DK165620B (da) 1992-12-28
FI853913A0 (fi) 1985-10-08
PH23982A (en) 1990-02-09
PT81347A (en) 1985-11-01
KR860003014A (ko) 1986-05-19
SE8504945L (sv) 1986-04-23
GB8426672D0 (en) 1984-11-28
GB2165751A (en) 1986-04-23
CN85107562A (zh) 1986-07-23
FI86252B (fi) 1992-04-30
FI86252C (fi) 1992-08-10
BG60934B2 (bg) 1996-06-28
SE8504945D0 (sv) 1985-10-21
CS270421B2 (en) 1990-06-13
ATA303285A (de) 1996-01-15
NL191308C (nl) 1995-05-16
PT81347B (pt) 1987-11-11
RU2101018C1 (ru) 1998-01-10
SG80290G (en) 1990-11-23
JPS61246129A (ja) 1986-11-01
CH667594A5 (de) 1988-10-31
BE903484A (fr) 1986-04-21
AU4880585A (en) 1986-05-01
DE3536896A1 (de) 1986-04-24
IT8522507A0 (it) 1985-10-16
NO170616B (no) 1992-08-03

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20051017