ZA858033B - Pharmaceutical compositions containing anthracycline glycosides - Google Patents

Pharmaceutical compositions containing anthracycline glycosides

Info

Publication number: ZA858033B
Authority: ZA; South Africa
Prior art keywords: pharmaceutical compositions; compositions containing; anthracycline glycosides; containing anthracycline; glycosides
Prior art date: 1984-10-22

Application number

ZA858033A

Other languages

English (en)

Inventor

Gaetano Gatti

Diego Oldani

Carlo Confalonieri

Luciano Gambini

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-22

Filing date

1985-10-18

Publication date

1986-06-25

1985-10-18 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1986-06-25 Publication of ZA858033B publication Critical patent/ZA858033B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA858033A 1984-10-22 1985-10-18 Pharmaceutical compositions containing anthracycline glycosides ZA858033B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB848426672A GB8426672D0 (en)	1984-10-22	1984-10-22	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
ZA858033B true ZA858033B (en)	1986-06-25

Family

ID=10568553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA858033A ZA858033B (en)	1984-10-22	1985-10-18	Pharmaceutical compositions containing anthracycline glycosides

Country Status (35)

Country	Link
US (4)	US4675311A (xx)
JP (1)	JPH0611700B2 (xx)
KR (1)	KR920005813B1 (xx)
CN (1)	CN85107562B (xx)
AT (1)	AT401345B (xx)
AU (1)	AU572003B2 (xx)
BE (1)	BE903484A (xx)
BG (1)	BG60934B2 (xx)
CA (1)	CA1248453A (xx)
CH (1)	CH667594A5 (xx)
CS (1)	CS270421B2 (xx)
DE (1)	DE3536896C2 (xx)
DK (1)	DK165620C (xx)
ES (1)	ES8605374A1 (xx)
FI (2)	FI853913A (xx)
FR (1)	FR2571966B1 (xx)
GB (2)	GB8426672D0 (xx)
GR (1)	GR852549B (xx)
HK (1)	HK94390A (xx)
HU (1)	HU197988B (xx)
IE (1)	IE56992B1 (xx)
IL (1)	IL76732A (xx)
IT (1)	IT1186779B (xx)
MY (1)	MY103956A (xx)
NL (1)	NL191308C (xx)
NO (1)	NO170616C (xx)
NZ (1)	NZ213885A (xx)
PH (1)	PH23982A (xx)
PT (1)	PT81347B (xx)
RU (2)	RU1836088C (xx)
SE (1)	SE467520B (xx)
SG (1)	SG80290G (xx)
UA (2)	UA19169A (xx)
YU (1)	YU46160B (xx)
ZA (1)	ZA858033B (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5124317A (en)	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.R.L.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) *	1985-08-02	1999-11-02	Pharmacia & Upjohn Company	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
DE3752368T2 (de) *	1986-12-05	2004-02-12	Pharmacia Italia S.P.A.	Doxorubicin enthaltende einspritzbare gebrauchsfertige Lösungen gegen Krebs
JP2603480B2 (ja) *	1987-08-05	1997-04-23	住友製薬株式会社	安定化されたアンスラサイクリン系製剤
DE3801178A1 (de) *	1988-01-18	1989-07-27	Hoechst Ag	Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
US6300362B1 (en)	1990-07-25	2001-10-09	Novartis Ag (Formerly Sandoz Ltd.)	Stabilized pharmaceutical compositions comprising acid donors
US6471943B1 (en)	1996-12-30	2002-10-29	Battelle Pulmonary Therapeutics, Inc.	Formulation and method for treating neoplasms by inhalation
US5942508A (en) *	1997-02-04	1999-08-24	Senju Pharmaceutical Co., Ltd.	Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
CA2476494C (en)	2002-02-22	2010-04-27	Schering Corporation	Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same
DK1474995T3 (da) *	2003-05-06	2013-02-18	Gumlink As	Fremgangsmåde til fremstilling af tyggegummigranulater, et gummisammensætningsekstruder- og granuleringssystem og et tyggegummiprodukt
US20090099346A1 (en) *	2003-07-02	2009-04-16	Victor Matvienko	Thermally stable crystalline epirubicin hydrochloride
US7485707B2 (en) *	2003-07-02	2009-02-03	Solux Corporation	Thermally stable crystalline epirubicin hydrochloride and method of making the same
US7314862B2 (en) *	2003-09-25	2008-01-01	Astellas Pharma Inc.	Antitumor agent
US7388083B2 (en) *	2005-03-07	2008-06-17	Solux Corporation	Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
BRPI0605832A2 (pt) *	2005-05-11	2009-05-26	Sicor Inc	glicosìdeos de antraciclina liofilizados estáveis
WO2007011743A2 (en)	2005-07-14	2007-01-25	Lipothera, Inc.	Sustained release enhanced lipolytic formulation for regional adipose tissue treatment
EP1976858B1 (en) *	2005-12-13	2016-01-06	Solux Corporation	Method for preparing 4-demethyldaunorubicin
US8802830B2 (en) *	2005-12-20	2014-08-12	Solux Corporation	Synthesis of epirubicin from 13-dihydrodaunorubicine
US8148338B2 (en) *	2006-02-22	2012-04-03	Supratek Pharma Inc.	Doxorubicin formulations for anti-cancer use
US7470672B2 (en) *	2006-07-31	2008-12-30	Savvipharm Inc.	Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives
AU2008250518B2 (en) *	2007-05-16	2013-09-12	Ktb Tumorforschungsgesellschaft Mbh	Low-viscous anthracycline formulation
US8227430B2 (en)	2007-09-04	2012-07-24	Meiji Seika Pharma Co., Ltd	Injectable, injection solution, and injection kit preparation
US20100234314A1 (en) *	2007-10-26	2010-09-16	Pfizer Inc.	Idarubicin for the treatment of lymphoma in a dog
US8357785B2 (en) *	2008-01-08	2013-01-22	Solux Corporation	Method of aralkylation of 4′-hydroxyl group of anthracylins
US9132084B2 (en)	2009-05-27	2015-09-15	Neothetics, Inc.	Methods for administration and formulations for the treatment of regional adipose tissue
CA2786618C (en) *	2010-01-15	2016-04-12	Lithera, Inc.	Lyophilized cake formulations
GB2485885B (en)	2010-11-24	2015-06-17	Neothetics Inc	Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging
DE102011103751A1 (de)	2011-05-31	2012-12-06	Heraeus Precious Metals Gmbh & Co. Kg	Kristallisierung von Epirubicinhydrochlorid
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP2931042B1 (en)	2012-12-13	2021-04-28	CytRx Corporation	Anthracycline formulations
NZ631022A (en)	2013-06-05	2018-05-25	Cytrx Corp	Cytotoxic agents for the treatment of cancer

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates
GB1506200A (en) *	1975-04-30	1978-04-05	Farmaceutici Italia	Glycosides
GB1567456A (en) *	1976-11-16	1980-05-14	Farmaceutici Italia	Daunomycin derivatives
GB2007645B (en) *	1977-10-17	1982-05-12	Stanford Res Inst Int	Benzyl anthracyclines and pharmaceutical compositions containing them
US4177264A (en) *	1977-10-17	1979-12-04	Sri International	N-benzyl anthracyclines
JPS563851A (en) *	1979-06-22	1981-01-16	Matsushita Electric Works Ltd	Fireplace in floor
JPS5756494A (en) *	1980-09-22	1982-04-05	Microbial Chem Res Found	New anthracyclin derivative
US4325947A (en) *	1981-05-12	1982-04-20	Farmitalia Carlo Erba S.P.A.	4-Demethoxy-4'-deoxydoxorubicin
IT1210476B (it) *	1981-05-28	1989-09-14	Erba Farmitalia	Antracicline.
US4438105A (en) *	1982-04-19	1984-03-20	Farmaitalia Carlo Erba S.P.A	4'-Iododerivatives of anthracycline glycosides
FI75834C (fi) *	1982-05-24	1988-08-08	Erba Farmitalia	Foerfarande foer framstaellning av antracyklinglykosidfoereningar.
US4464529A (en) *	1982-07-20	1984-08-07	Sri International	Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
CA1248944A (en) *	1982-09-28	1989-01-17	Gareth J. Thomas	Anthracycline glycosides
JPS5982395A (ja) *	1982-11-02	1984-05-12	Microbial Chem Res Found	アントラサイクリン化合物、その製造法およびその用途
GR79729B (xx) *	1982-12-20	1984-10-31	Univ Ohio State Res Found
JPS6092212A (ja) *	1983-10-26	1985-05-23	Kyowa Hakko Kogyo Co Ltd	ドキソルビシン塩の製剤
US4537882A (en) *	1984-05-10	1985-08-27	Ohio State University	4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

1984
- 1984-10-22 GB GB848426672A patent/GB8426672D0/en active Pending
1985
- 1985-10-03 ES ES547578A patent/ES8605374A1/es not_active Expired
- 1985-10-08 FI FI853913A patent/FI853913A/fi not_active Application Discontinuation
- 1985-10-15 HU HU853988A patent/HU197988B/hu unknown
- 1985-10-15 CN CN85107562A patent/CN85107562B/zh not_active Expired
- 1985-10-16 IT IT22507/85A patent/IT1186779B/it active Protection Beyond IP Right Term
- 1985-10-16 FI FI854035A patent/FI86252C/fi not_active IP Right Cessation
- 1985-10-16 YU YU164485A patent/YU46160B/sh unknown
- 1985-10-16 DE DE3536896A patent/DE3536896C2/de not_active Expired - Lifetime
- 1985-10-16 US US06/788,158 patent/US4675311A/en not_active Expired - Lifetime
- 1985-10-17 JP JP60230055A patent/JPH0611700B2/ja not_active Expired - Lifetime
- 1985-10-17 AU AU48805/85A patent/AU572003B2/en not_active Expired
- 1985-10-17 IL IL76732A patent/IL76732A/xx not_active IP Right Cessation
- 1985-10-17 CH CH4476/85A patent/CH667594A5/de not_active IP Right Cessation
- 1985-10-18 UA UA3964940A patent/UA19169A/uk unknown
- 1985-10-18 ZA ZA858033A patent/ZA858033B/xx unknown
- 1985-10-18 NZ NZ213885A patent/NZ213885A/en unknown
- 1985-10-18 GB GB08525709A patent/GB2165751B/en not_active Expired
- 1985-10-18 UA UA5010680A patent/UA34419C2/uk unknown
- 1985-10-18 AT AT0303285A patent/AT401345B/de not_active IP Right Cessation
- 1985-10-18 PH PH32947A patent/PH23982A/en unknown
- 1985-10-18 RU SU853964940A patent/RU1836088C/ru active
- 1985-10-21 CA CA000493459A patent/CA1248453A/en not_active Expired
- 1985-10-21 NL NL8502869A patent/NL191308C/xx not_active IP Right Cessation
- 1985-10-21 DK DK481585A patent/DK165620C/da not_active IP Right Cessation
- 1985-10-21 SE SE8504945A patent/SE467520B/sv not_active IP Right Cessation
- 1985-10-21 KR KR1019850007740A patent/KR920005813B1/ko not_active IP Right Cessation
- 1985-10-21 FR FR8515596A patent/FR2571966B1/fr not_active Expired
- 1985-10-21 PT PT81347A patent/PT81347B/pt unknown
- 1985-10-21 IE IE2593/85A patent/IE56992B1/en not_active IP Right Cessation
- 1985-10-21 NO NO854194A patent/NO170616C/no not_active IP Right Cessation
- 1985-10-21 BE BE0/215752A patent/BE903484A/fr not_active IP Right Cessation
- 1985-10-22 CS CS857565A patent/CS270421B2/cs not_active IP Right Cessation
- 1985-10-22 GR GR852549A patent/GR852549B/el unknown
1986
- 1986-08-06 US US06/893,613 patent/US4840938A/en not_active Expired - Lifetime
1988
- 1988-12-30 MY MYPI88001588A patent/MY103956A/en unknown
1990
- 1990-09-26 US US07/588,526 patent/US5091372A/en not_active Expired - Lifetime
- 1990-09-28 US US07/590,536 patent/US5091373A/en not_active Expired - Lifetime
- 1990-10-03 SG SG802/90A patent/SG80290G/en unknown
- 1990-11-15 HK HK943/90A patent/HK94390A/xx not_active IP Right Cessation
1992
- 1992-01-30 RU SU5010680A patent/RU2101018C1/ru active
1994
- 1994-02-23 BG BG098530A patent/BG60934B2/bg unknown

Also Published As

Publication number	Publication date
IE56992B1 (en)	1992-02-26
SE8504945D0 (sv)	1985-10-21
US4840938A (en)	1989-06-20
IL76732A (en)	1989-07-31
US5091373A (en)	1992-02-25
NL8502869A (nl)	1986-05-16
DK481585A (da)	1986-04-23
HUT40759A (en)	1987-02-27
IL76732A0 (en)	1986-02-28
FI854035L (fi)	1986-04-23
RU1836088C (ru)	1993-08-23
DK165620B (da)	1992-12-28
US5091372A (en)	1992-02-25
FI86252B (fi)	1992-04-30
IE852593L (en)	1986-04-22
JPS61246129A (ja)	1986-11-01
FR2571966A1 (fr)	1986-04-25
BG60934B2 (bg)	1996-06-28
MY103956A (en)	1993-10-30
FI853913A0 (fi)	1985-10-08
DK481585D0 (da)	1985-10-21
IT8522507A0 (it)	1985-10-16
FR2571966B1 (fr)	1988-04-15
NO170616C (no)	1992-11-11
NO170616B (no)	1992-08-03
FI86252C (fi)	1992-08-10
KR860003014A (ko)	1986-05-19
FI853913A (fi)	1986-04-23
AU4880585A (en)	1986-05-01
NL191308C (nl)	1995-05-16
PH23982A (en)	1990-02-09
AU572003B2 (en)	1988-04-28
CS270421B2 (en)	1990-06-13
UA19169A (uk)	1997-12-25
DE3536896A1 (de)	1986-04-24
UA34419C2 (uk)	2001-03-15
PT81347A (en)	1985-11-01
NO854194L (no)	1986-04-23
SE467520B (sv)	1992-08-03
CS756585A2 (en)	1989-11-14
CA1248453A (en)	1989-01-10
YU164485A (en)	1987-10-31
CN85107562B (zh)	1988-06-01
HK94390A (en)	1990-11-23
SG80290G (en)	1990-11-23
CN85107562A (zh)	1986-07-23
GB8426672D0 (en)	1984-11-28
NZ213885A (en)	1988-05-30
NL191308B (nl)	1994-12-16
ATA303285A (de)	1996-01-15
JPH0611700B2 (ja)	1994-02-16
KR920005813B1 (ko)	1992-07-20
ES547578A0 (es)	1986-03-16
GR852549B (xx)	1986-02-24
FI854035A0 (fi)	1985-10-16
DE3536896C2 (de)	1996-11-14
GB2165751A (en)	1986-04-23
SE8504945L (sv)	1986-04-23
AT401345B (de)	1996-08-26
CH667594A5 (de)	1988-10-31
DK165620C (da)	1993-06-01
YU46160B (sh)	1993-05-28
GB2165751B (en)	1988-08-17
HU197988B (en)	1989-07-28
US4675311A (en)	1987-06-23
ES8605374A1 (es)	1986-03-16
RU2101018C1 (ru)	1998-01-10
GB8525709D0 (en)	1985-11-20
PT81347B (pt)	1987-11-11
BE903484A (fr)	1986-04-21
IT1186779B (it)	1987-12-16

Publication	Publication Date	Title
GB2165751B (en)	1988-08-17	Pharmaceutical compositions containing anthracycline glycosides
NZ212540A (en)	1989-01-27	Ganglioside derivatives, and pharmaceutical compositions containing such
GB2165451B (en)	1988-07-06	Pharmaceutical compositions
IL77138A0 (en)	1986-04-29	Pharmaceutical compositions containing 1-heteroaryl-4-arylpyrazolin-5-ones
ZA859731B (en)	1987-08-26	Pharmaceutical compositions containing tetrahydrobenzthiazoles
GB2118540B (en)	1985-08-14	Anthracycline glycosides
NZ192758A (en)	1982-03-09	Anthracycline glycosides and pharmaceutical compositions
NZ222113A (en)	1989-11-28	Anthracycline glycosides: pharmaceutical compositions and intermediates
IL69778A0 (en)	1983-12-30	Anthracycline glycosides,their manufacture and pharmaceutical compositions containing them
IL82820A0 (en)	1987-12-20	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
NZ218256A (en)	1988-11-29	Anthracycline glycosides and pharmaceutical compositions
GB8410636D0 (en)	1984-05-31	Pharmaceutical substances/compositions
IL63287A (en)	1984-10-31	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
ZA833525B (en)	1984-06-27	Anthracycline glycosides
GB2091243B (en)	1984-06-20	Anthracycline glycosides
GB2116169B (en)	1985-09-04	Anthracycline glycosides
GB2106900B (en)	1985-06-12	Anthracycline glycosides
GB2120667B (en)	1985-06-05	Anthracycline glycosides
GB8520835D0 (en)	1985-09-25	Anthracycline glycosides
MY8400399A (en)	1984-12-31	Anthracycline glycosides
IE851662L (en)	1986-01-03	Anthracycline glycosides
IE840388L (en)	1984-08-23	Pharmaceutical compositions containing imidiazole¹derivatives
IE862977L (en)	1987-05-19	Anthracycline glycosides
IL83228A (en)	1988-07-31	6-deoxyanthracycline glycosides,their preparation and pharmaceutical compositions containing them
IL83228A0 (en)	1987-12-31	6-deoxyanthracycline glycosides,their preparation and pharmaceutical compositions containing them