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HK1223394A1 - 切割 細胞受體α基因的 歸巢核酸內切酶及其用途 - Google Patents

切割 細胞受體α基因的 歸巢核酸內切酶及其用途

Info

Publication number
HK1223394A1
HK1223394A1 HK16111488.8A HK16111488A HK1223394A1 HK 1223394 A1 HK1223394 A1 HK 1223394A1 HK 16111488 A HK16111488 A HK 16111488A HK 1223394 A1 HK1223394 A1 HK 1223394A1
Authority
HK
Hong Kong
Prior art keywords
laglidadg
cell receptor
receptor alpha
homing endonuclease
alpha gene
Prior art date
Application number
HK16111488.8A
Other languages
English (en)
Inventor
Alexander Astrakhan
Jordan Jarjour
Original Assignee
Cellectis Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellectis Sa filed Critical Cellectis Sa
Publication of HK1223394A1 publication Critical patent/HK1223394A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK16111488.8A 2013-05-31 2016-09-30 切割 細胞受體α基因的 歸巢核酸內切酶及其用途 HK1223394A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201370303 2013-05-31
PCT/EP2014/061189 WO2014191527A1 (en) 2013-05-31 2014-05-28 A laglidadg homing endonuclease cleaving the t cell receptor alpha gene and uses thereof

Publications (1)

Publication Number Publication Date
HK1223394A1 true HK1223394A1 (zh) 2017-07-28

Family

ID=48628226

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16111488.8A HK1223394A1 (zh) 2013-05-31 2016-09-30 切割 細胞受體α基因的 歸巢核酸內切酶及其用途

Country Status (9)

Country Link
US (1) US10000746B2 (zh)
EP (1) EP3004338B1 (zh)
JP (1) JP6450371B2 (zh)
AU (1) AU2014273091B2 (zh)
CA (1) CA2913872C (zh)
DK (1) DK3004338T3 (zh)
ES (1) ES2716867T3 (zh)
HK (1) HK1223394A1 (zh)
WO (1) WO2014191527A1 (zh)

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Also Published As

Publication number Publication date
US20160130569A1 (en) 2016-05-12
CA2913872C (en) 2022-01-18
US10000746B2 (en) 2018-06-19
EP3004338B1 (en) 2019-01-02
ES2716867T3 (es) 2019-06-17
JP2016520320A (ja) 2016-07-14
AU2014273091A1 (en) 2015-12-03
AU2014273091B2 (en) 2019-12-12
EP3004338A1 (en) 2016-04-13
JP6450371B2 (ja) 2019-01-09
WO2014191527A1 (en) 2014-12-04
DK3004338T3 (en) 2019-04-08
CA2913872A1 (en) 2014-12-04

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