HK1042706A1 - Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments - Google Patents
Low adenosine anti-sense oligonucleotide agent, composition, kit and treatmentsInfo
- Publication number
- HK1042706A1 HK1042706A1 HK02102614.0A HK02102614A HK1042706A1 HK 1042706 A1 HK1042706 A1 HK 1042706A1 HK 02102614 A HK02102614 A HK 02102614A HK 1042706 A1 HK1042706 A1 HK 1042706A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatments
- kit
- composition
- sense oligonucleotide
- oligonucleotide agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
- C12N2310/334—Modified C
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9521298P | 1998-08-03 | 1998-08-03 | |
| PCT/US1999/017712 WO2000009525A2 (en) | 1998-08-03 | 1999-08-03 | Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1042706A1 true HK1042706A1 (en) | 2002-08-23 |
Family
ID=22250687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02102614.0A HK1042706A1 (en) | 1998-08-03 | 2002-04-08 | Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1102786A4 (en) |
| CN (1) | CN1317009A (en) |
| AU (1) | AU5337499A (en) |
| CA (1) | CA2333901A1 (en) |
| HK (1) | HK1042706A1 (en) |
| WO (1) | WO2000009525A2 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7034007B1 (en) | 1995-06-07 | 2006-04-25 | East Carolina University | Low adenosine anti-sense oligonucleotide, compositions, kit & method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) & surfactant depletion |
| US6825174B2 (en) | 1995-06-07 | 2004-11-30 | East Carolina University | Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation |
| JP2002539831A (en) * | 1999-03-26 | 2002-11-26 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | 47 human secreted proteins |
| EP1165123A4 (en) * | 1999-03-26 | 2002-09-11 | Human Genome Sciences Inc | 48 human secreted proteins |
| CA2330022A1 (en) * | 1999-04-06 | 2000-10-26 | East Carolina University | Low adenosine anti-sense oligonucleotide, compositions, kit and method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) and surfactant depletion |
| US6489151B1 (en) * | 2000-03-27 | 2002-12-03 | The Research Foundation Of State University Of New York | Biologically active alternative form of the IKKα IκB kinase |
| DE10019252A1 (en) * | 2000-04-18 | 2001-10-31 | Klaus Karl Degitz | Polydeoxyribonucleotides to inhibit ICAM-1 gene expression |
| DE10049549A1 (en) | 2000-10-06 | 2002-05-02 | Markus Hecker | Inhibitor of the transcription factor IFR-1, useful for treating e.g. transplant rejection and autoimmune disease, reduces expression of CD40 |
| PT1406667E (en) * | 2001-07-06 | 2008-05-23 | Topigen Pharmaceuticals Inc | Methods for increasing in vivo efficacy of oligonucleotides and inhibiting inflammation in mammals |
| WO2003087408A2 (en) * | 2002-04-05 | 2003-10-23 | University Court Of The University Of Edinburgh | Schizophrenia associated genes |
| AR040996A1 (en) | 2002-08-19 | 2005-04-27 | Coley Pharm Group Inc | IMMUNE STIMULATING NUCLEIC ACIDS |
| CN1322899C (en) * | 2004-02-11 | 2007-06-27 | 中国科学院上海生命科学研究院 | Anti cancer gene medicinal composition, micromolecule interfere RNA and its screening method |
| NZ554723A (en) | 2004-10-29 | 2009-12-24 | Topigen Pharmaceuticals Inc | Antisense oligonucleotides against CCR3 chemokine receptor |
| WO2007021807A1 (en) | 2005-08-12 | 2007-02-22 | Schering Corporation | Mcp1 fusions |
| US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| US10017762B2 (en) * | 2010-11-24 | 2018-07-10 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Compositions and methods for treating or preventing lupus |
| MX340053B (en) * | 2011-06-15 | 2016-06-22 | Grifols Therapeutics Inc * | Methods, compositions, and kits for determining human immunodeficiency virus (hiv). |
| CN102866153B (en) * | 2012-09-29 | 2014-08-13 | 郑州安图生物工程股份有限公司 | Prostatitis joint-detection kit |
| RU2015138544A (en) * | 2013-03-11 | 2017-04-18 | Юниверсити Оф Норс Керолайна Эт Чапел Хилл | Compositions and methods for targeting O-linked N-acetylglucosamine transferase and stimulating wound healing |
| JP2023548597A (en) * | 2020-10-29 | 2023-11-17 | エー． ガルシア－ブランコ，マリアーノ | Soluble interleukin-7 receptor (sIL7R) modulation therapy to treat cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3739785B2 (en) * | 1991-11-26 | 2006-01-25 | アイシス ファーマシューティカルズ，インコーポレイティド | Enhanced triple and double helix shaping using oligomers containing modified pyrimidines |
| US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US6498147B2 (en) * | 1992-05-22 | 2002-12-24 | The Scripps Research Institute | Suppression of nuclear factor-κb dependent processes using oligonucleotides |
| US5994315A (en) * | 1995-06-07 | 1999-11-30 | East Carolina University | Low adenosine agent, composition, kit and method for treatment of airway disease |
| US5856462A (en) * | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
| US5932557A (en) * | 1997-08-12 | 1999-08-03 | Mustafa; S. Jamal | Adenosine A1 receptor antisense oligonucleotide treatment of alcohol and marijuana-induced psychomotor impairments |
| CA2333087C (en) * | 1998-05-21 | 2014-07-08 | Isis Pharmaceuticals Inc. | Compositions and methods for the pulmonary delivery of nucleic acids |
-
1999
- 1999-08-03 CA CA002333901A patent/CA2333901A1/en not_active Abandoned
- 1999-08-03 CN CN99809303A patent/CN1317009A/en active Pending
- 1999-08-03 EP EP99939006A patent/EP1102786A4/en not_active Withdrawn
- 1999-08-03 WO PCT/US1999/017712 patent/WO2000009525A2/en active Search and Examination
- 1999-08-03 AU AU53374/99A patent/AU5337499A/en not_active Abandoned
-
2002
- 2002-04-08 HK HK02102614.0A patent/HK1042706A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2333901A1 (en) | 2000-02-24 |
| WO2000009525A3 (en) | 2000-05-18 |
| EP1102786A2 (en) | 2001-05-30 |
| AU5337499A (en) | 2000-03-06 |
| CN1317009A (en) | 2001-10-10 |
| WO2000009525A2 (en) | 2000-02-24 |
| EP1102786A4 (en) | 2002-03-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1042706A1 (en) | Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments | |
| AP2000002015A0 (en) | Pyrrolo¬2,3d¾pyrimidine compositions and their use | |
| HUP0003364A3 (en) | Quinoline-indole antimicrobial agents, uses and compositions related thereto | |
| IL143379A0 (en) | ANTISENSE OLIGONUCLEOTIDE AGAINST HUMAN AChE AND USES THEREOF | |
| ZA994492B (en) | Detergent cosmetic compositions and use. | |
| IL189430A0 (en) | 13-membered azalides and their use as antibiotic agents | |
| MXPA03002273A (en) | Shampoo and body wash composition. | |
| HUP0200409A2 (en) | Valdecoxib compositions, process for their preparation and their use | |
| IL138609A0 (en) | Antipicornaviral compounds, their preparation and use | |
| AU7124398A (en) | Biflavinoids and derivatives thereof as antiviral agents, alone or in combination with at least one known antiviral agent | |
| HUP0103845A3 (en) | Disinfecting composition and its use | |
| GB9817235D0 (en) | Compound,composition and use | |
| GB2324727B (en) | Antimicrobial compositions, their preparation and use | |
| HK1031725A1 (en) | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | |
| ZA996814B (en) | Aluminosilicate compositions, preparation and use. | |
| HUP0102808A3 (en) | Ectoparasiticide agents | |
| GB0026467D0 (en) | Compound, composition and use | |
| AU2002214477A1 (en) | Modified nucleosides and nucleotides and use thereof | |
| HK1042847A1 (en) | Bone-pathobolism treating agent | |
| GB9903447D0 (en) | Compound, composition and use | |
| HUP0104350A3 (en) | Synergetic fungicidal composition comprising thieno[2,3-d]pyrimidin-4-one and its use | |
| AU6459199A (en) | Antisense oligonucleotides which inhibit telomerase's activity and their uses | |
| AU2001240098A1 (en) | 4'-thio-l-xylo furanosyl nucleosides, precursors thereof, preparation and use thereof | |
| GB9917593D0 (en) | Compound, composition, process and use | |
| GB9820631D0 (en) | Hair treatment composition, method and use |