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GT201600215A - Compuestos de heteroarilo o arilo bicíclicos fusionados y su uso como inhibidores de irak4 - Google Patents

Compuestos de heteroarilo o arilo bicíclicos fusionados y su uso como inhibidores de irak4

Info

Publication number
GT201600215A
GT201600215A GT201600215A GT201600215A GT201600215A GT 201600215 A GT201600215 A GT 201600215A GT 201600215 A GT201600215 A GT 201600215A GT 201600215 A GT201600215 A GT 201600215A GT 201600215 A GT201600215 A GT 201600215A
Authority
GT
Guatemala
Prior art keywords
compounds
heteroarilo
fusioned
arilo
bicyclic
Prior art date
Application number
GT201600215A
Other languages
English (en)
Inventor
David Randolph Anderson
Mark Edward Bunnage
Kevin Joseph Curran
Christoph Martin Dehnhardt
Lori Krim Gavrin
Joel Adam Goldberg
Seungil Han
David Hepworth
Horng-Chih Huang
Arthur Lee
Katherine Lin Lee
Frank Eldridge Lovering
Michael Dennis Lowe
John Paul Mathias
Nikolaos Papaioannou
Akshay Patny
Betsy Susan Pierce
Eddine Saiah
Joseph Walter Strohbach
John David Trzupek
Richard Vargas
Xiaolun Wang
Stephen Wayne Wright
Christoph Wolfgang Zapf
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GT201600215A publication Critical patent/GT201600215A/es

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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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Abstract

LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS ÚTILES PARA EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNITARIAS E INFLAMATORIAS ASOCIADAS A LA QUINASA ASOCIADA AL RECEPTOR DE LA INTERLEUCINA-1 (IR) Y, MÁS EN PARTICULAR, A COMPUESTOS QUE MODULAN LA FUNCIÓN DE IRAK4. TAMBIÉN SE DESCRIBEN COMPOSICIONES FARMACÉUTICAS, MÉTODOS DE SÍNTESIS E INTERMEDIARIOS CORRESPONDIENTES.
GT201600215A 2014-04-04 2016-10-04 Compuestos de heteroarilo o arilo bicíclicos fusionados y su uso como inhibidores de irak4 GT201600215A (es)

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