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GB975598A - Alkenylamines and pharmaceutical preparations containing them - Google Patents

Alkenylamines and pharmaceutical preparations containing them

Info

Publication number
GB975598A
GB975598A GB1502/64A GB150264A GB975598A GB 975598 A GB975598 A GB 975598A GB 1502/64 A GB1502/64 A GB 1502/64A GB 150264 A GB150264 A GB 150264A GB 975598 A GB975598 A GB 975598A
Authority
GB
United Kingdom
Prior art keywords
alkenylamines
salts
pharmaceutical preparations
oral administration
physiologically tolerable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1502/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB975598A publication Critical patent/GB975598A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises alkenylamines of the formula <FORM:0975598/C1/1> wherein R and R1 are hydrogen atoms or methoxy groups, physiologically tolerable acid addition salts thereof and pharmaceutical preparations comprising these alkenylamines or their salts in admixture or conjunction with a carrier suitable for parenteral or oral administration. The alkenylamines are made by reacting the corresponding 1-phenyl -2- [11, 11-diphenyl-11-hydroxy-propyl -(31)]-amino-propane with a dehydrating agent such as p-toluenesulphonic acid. Suitable physiologically tolerable salts include the salts with hydrohalic, sulphuric, phosphoric, sulphamic, formic, acetic, propionic, lactic, glycollic, gluconic, maleic, succinic, tartaric, benzoic, salicylic, citric, aceturic, hydroxyethanesulphonic and ethylenediaminetetracetic acids. The pharmaceutical preparations for oral administration suitably take the form of tablets or dragees. They have a favourable action on the cardiac and blood vascular circulation.
GB1502/64A 1959-12-28 1960-12-28 Alkenylamines and pharmaceutical preparations containing them Expired GB975598A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF30188A DE1144735B (en) 1959-12-28 1959-12-28 Process for the production of basic substituted propanols and alkenylamines obtainable therefrom by splitting off water

Publications (1)

Publication Number Publication Date
GB975598A true GB975598A (en) 1964-11-18

Family

ID=7093651

Family Applications (2)

Application Number Title Priority Date Filing Date
GB44532/60A Expired GB975597A (en) 1959-12-28 1960-12-28 Basically substituted propanols and pharmaceutical preparations containing them
GB1502/64A Expired GB975598A (en) 1959-12-28 1960-12-28 Alkenylamines and pharmaceutical preparations containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB44532/60A Expired GB975597A (en) 1959-12-28 1960-12-28 Basically substituted propanols and pharmaceutical preparations containing them

Country Status (7)

Country Link
BE (1) BE598605A (en)
CH (3) CH412857A (en)
DE (1) DE1144735B (en)
DK (2) DK103446C (en)
GB (2) GB975597A (en)
NL (1) NL259249A (en)
OA (1) OA01378A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213219B (en) * 1984-09-28 1989-12-14 Consiglio Nazionale Ricerche AMINO ALKYLNAPHTHALENIC DERIVATIVES FOR PHARMACOLOGICAL ACTIVITY.
DE102005033732B4 (en) * 2005-05-27 2014-02-13 Grünenthal GmbH Separation of stereoisomeric N, N-dialkylamino-2-alkyl-3-hydroxy-3-phenyl-alkanes

Also Published As

Publication number Publication date
NL259249A (en)
BE598605A (en) 1961-06-28
CH415602A (en) 1966-06-30
DK109325C (en) 1968-04-16
CH415601A (en) 1966-06-30
GB975597A (en) 1964-11-18
DE1144735B (en) 1963-03-07
OA01378A (en) 1969-07-04
CH412857A (en) 1966-05-15
DK103446C (en) 1966-01-03

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