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GB2251552A - Skin care composition comprising coumarin or a derivative thereof - Google Patents

Skin care composition comprising coumarin or a derivative thereof Download PDF

Info

Publication number
GB2251552A
GB2251552A GB9126794A GB9126794A GB2251552A GB 2251552 A GB2251552 A GB 2251552A GB 9126794 A GB9126794 A GB 9126794A GB 9126794 A GB9126794 A GB 9126794A GB 2251552 A GB2251552 A GB 2251552A
Authority
GB
United Kingdom
Prior art keywords
coumarin
skin care
care composition
derivative
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9126794A
Other versions
GB9126794D0 (en
Inventor
Edward William Duck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB9126794D0 publication Critical patent/GB9126794D0/en
Publication of GB2251552A publication Critical patent/GB2251552A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

A skin care composition, for example a cream or a lotion, comprises at least one compound selected from coumarin, a naturally occurring substance containing coumarin, a derivative of coumarin and a derivative of a naturally occurring substance containing coumarin. Preferred compositions comprise up to 5% by weight of the composition of a coumarinic ester formed from a tocopherol and/or a chiral amyl alcohol.

Description

Skin Care Composition This invention relates to a skin care composition.
Skin care compositions are frequently applied to the skin to reduce dryness and to provide protection from the effects of sunlight.
It is well known that some organic chemicals may offer protection against the harmful ultra-violet radiation of the sun and such materials have been incorporated into skin care compositions, usually creams or lotions.
According to the present invention a skin care composition comprises at least one compound selected from coumarin, a naturally occurring substance containing coumarin and a derivative of coumarin or of such a coumarin containing substance.
The skin care composition may be a cream or a lotion.
Specific examples of compounds for use in compositions which fall within the scope of my invention are coumarin itself (also known as benzopyrone or the anhydride of coumarinic acid), coumarinic acid (not usually obtainable in the free state), coumarinic esters, salts of coumarinic acid and Tonka (Touquin) bean extracts. The compound may be used as such or in the form of a glycoside or attached to a polymeric material which may enable a continuous slow release dosage of the compound to be obtained over a longer period of time than can be achieved using the same compound in a low molecular state.
By the use of a skin care composition according to my invention it is possible to obtain some protection against the development of skin cancers. Surprisingly such compositions may also reduce melanomas already in existence.
The coumarin compound which is the essential ingredient of a skin care composition is included in an amount of up to 5% by weight of the skin care composition. Other ingredients of the composition are those well known in the art such as avocado pear oil, liquid paraffin and a dispersant such as sorbitan monolaurate or diglycollaurate. Generally the solids content of total ingredients of the composition is 25-602 by weight, the balance being water.
The composition is prepared by mixing the ingredients and the water to form an emulsion (e.g. a lotion or a cream).
The following Examples illustrate formulations for skin care compositions according to my invention (all percentages being by weight of total).
Example 1 - Composition of a basic thick skin cream.
Sorbitan monolaurate 5X Avocado pear oil 25X Coumarin dissolved in the oil 1X Water 69Z Preservative (e.g. parahydroxyethylbenzoate 0.1-0.25X) may be added and any perfumery requirement.
Example 2 - Composition of a rich milky base.
Liquid paraffin 40X Tonka bean extract 2Z Diglycollaurate 12Z Water 45Z Preservative and perfume as required.
Example 3 A composition is prepared as in Example 1 substituting a coumarin ester formed from D-alpha tocopherol (the naturally occurring form of Vitamin E) for the coumarin.
Example 4 A composition is prepared as in Example 1 substituting a coumarin ester formed from a chiral amyl alcohol (in this case L-2-methyl butanol-l) for the coumar.n.

Claims (6)

Claims
1. A skin care composition comprising at least one compound selected from coumarin, a naturally occurring substance containing coumarin, a derivative of coumarin and a derivative of a naturally occurring substance containing coumarin.
2. A skin care composition comprising at least one of coumarin, a coumarinic ester, a salt of coumarinic acid and Tonka bean extract.
3. A skin care composition according to claim 1 or claim 2 comprising a coumarinic ester ic formed from a tocopherol and/or a chiral amyl alcohol.
4. A skin care composition according to any one of claims l to 3 wherein the coumarin compound comprises up to 5X by weight of the skin care composition.
5. A Skin care composition according to any one of claims 1 to 4 in the form of a lotion or cream.
6. A skin care composition substantially as hereinbefore described with reference to the examples.
GB9126794A 1990-12-19 1991-12-18 Skin care composition comprising coumarin or a derivative thereof Withdrawn GB2251552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027449A GB9027449D0 (en) 1990-12-19 1990-12-19 Skin care composition

Publications (2)

Publication Number Publication Date
GB9126794D0 GB9126794D0 (en) 1992-02-19
GB2251552A true GB2251552A (en) 1992-07-15

Family

ID=10687196

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909027449A Pending GB9027449D0 (en) 1990-12-19 1990-12-19 Skin care composition
GB9126794A Withdrawn GB2251552A (en) 1990-12-19 1991-12-18 Skin care composition comprising coumarin or a derivative thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909027449A Pending GB9027449D0 (en) 1990-12-19 1990-12-19 Skin care composition

Country Status (1)

Country Link
GB (2) GB9027449D0 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001001A2 (en) * 1994-06-28 1996-01-11 Piller-Gmbh Electric motor
CN100415207C (en) * 2005-03-29 2008-09-03 上海应用技术学院 Sunscreen cream containing natural plant sunscreen component and its preparation method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1367539A (en) * 1971-11-26 1974-09-18 Int Flavors & Fragrances Inc Coumarin sun-screening compounds and compositions containing them
GB1575095A (en) * 1976-07-29 1980-09-17 Oreal Anti-sunburn polymers
EP0166221A2 (en) * 1984-05-29 1986-01-02 HENKEL CORPORATION (a Delaware corp.) Sunscreen composition and method of use
US4616033A (en) * 1985-03-14 1986-10-07 Lamorna Investments Proprietary Ltd. 7 hydroxy-coumarin as a treatment for high protein oedemas
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1367539A (en) * 1971-11-26 1974-09-18 Int Flavors & Fragrances Inc Coumarin sun-screening compounds and compositions containing them
GB1575095A (en) * 1976-07-29 1980-09-17 Oreal Anti-sunburn polymers
EP0166221A2 (en) * 1984-05-29 1986-01-02 HENKEL CORPORATION (a Delaware corp.) Sunscreen composition and method of use
US4616033A (en) * 1985-03-14 1986-10-07 Lamorna Investments Proprietary Ltd. 7 hydroxy-coumarin as a treatment for high protein oedemas
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS Vol 106 no 6: 38213s & Contact DermatitisVol 15 no 3 pages 157-63 *
CHEMICAL ABSTRACTS Vol 107 no 14: 120854f *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001001A2 (en) * 1994-06-28 1996-01-11 Piller-Gmbh Electric motor
WO1996001001A3 (en) * 1994-06-28 1996-03-07 Piller Gmbh Electric motor
CN100415207C (en) * 2005-03-29 2008-09-03 上海应用技术学院 Sunscreen cream containing natural plant sunscreen component and its preparation method

Also Published As

Publication number Publication date
GB9027449D0 (en) 1991-02-06
GB9126794D0 (en) 1992-02-19

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)