GB1421526A - Penicillins and cephalosporins - Google Patents
Penicillins and cephalosporinsInfo
- Publication number
- GB1421526A GB1421526A GB611574A GB611574A GB1421526A GB 1421526 A GB1421526 A GB 1421526A GB 611574 A GB611574 A GB 611574A GB 611574 A GB611574 A GB 611574A GB 1421526 A GB1421526 A GB 1421526A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phconhch
- penam
- cor
- feb
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1421526 Penicillin and cephalosporin esters SOC FARMACEUTICI ITALIA SpA 11 Feb 1974 [14 Feb 1973] 06115/74 Heading C2C The invention comprises penam-3-carboxylic acids and ceph-3-em-4-carboxylic acids in which the carboxyl group is esterified with the alcohol HOCHRNR<SP>1</SP>COR<SP>2</SP>, where R and R<SP>1</SP> are each H or C 1-4 alkyl, and R<SP>2</SP> is H, up to C 10 alkyl or cycloalkyl, optionally substituted Ph or naphthyl, or pyrrolyl, thienyl, furyl or pyridyl. In examples, these compounds are prepared by reacting a salt of the appropriate acid with the chloride ClCHRNR<SP>1</SP>COR<SP>2</SP>. Details are also given for the preparation of the intermediates PhCONHCH 2 OH and PhCONHCH 2 Cl. Therapeutic compositions for oral or parenteral administration comprise the above penam- and cephem-derived esters, which in the Specification are tested against Staphylococcus aureus.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2035873 | 1973-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1421526A true GB1421526A (en) | 1976-01-21 |
Family
ID=11166010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB611574A Expired GB1421526A (en) | 1973-02-14 | 1974-02-11 | Penicillins and cephalosporins |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5418277B2 (en) |
| AT (1) | AT329179B (en) |
| BE (1) | BE810969A (en) |
| CH (1) | CH592670A5 (en) |
| DE (1) | DE2406817A1 (en) |
| ES (1) | ES423178A1 (en) |
| FR (1) | FR2216995B1 (en) |
| GB (1) | GB1421526A (en) |
| NL (1) | NL7401782A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0095341A1 (en) * | 1982-05-24 | 1983-11-30 | Pfizer Inc. | Penicillanic acid dioxide prodrug |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8300295D0 (en) * | 1983-01-06 | 1983-02-09 | Erba Farmitalia | Penem esters |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1491583A (en) * | 1965-07-22 | 1967-08-11 | Bristol Myers Co | Production of new activated esters of 6-aminopenicillanic acid |
| US3873521A (en) * | 1970-09-17 | 1975-03-25 | Astra Laekemedel Ab | Esters of {60 -amino penicillins |
| GB1425933A (en) * | 1972-03-13 | 1976-02-25 | Astra Laekemedel Ab | Cephalosporins |
| GB1426869A (en) * | 1972-03-13 | 1976-03-03 | Astra Laekemedel Ab | Penicillins |
-
1974
- 1974-02-08 NL NL7401782A patent/NL7401782A/xx not_active Application Discontinuation
- 1974-02-11 AT AT105874A patent/AT329179B/en not_active IP Right Cessation
- 1974-02-11 GB GB611574A patent/GB1421526A/en not_active Expired
- 1974-02-12 FR FR7404609A patent/FR2216995B1/fr not_active Expired
- 1974-02-12 JP JP1751374A patent/JPS5418277B2/ja not_active Expired
- 1974-02-13 CH CH196074A patent/CH592670A5/xx not_active IP Right Cessation
- 1974-02-13 ES ES423178A patent/ES423178A1/en not_active Expired
- 1974-02-13 BE BE140855A patent/BE810969A/en unknown
- 1974-02-13 DE DE19742406817 patent/DE2406817A1/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0095341A1 (en) * | 1982-05-24 | 1983-11-30 | Pfizer Inc. | Penicillanic acid dioxide prodrug |
Also Published As
| Publication number | Publication date |
|---|---|
| ES423178A1 (en) | 1976-05-01 |
| BE810969A (en) | 1974-08-13 |
| CH592670A5 (en) | 1977-10-31 |
| DE2406817A1 (en) | 1974-08-22 |
| JPS5418277B2 (en) | 1979-07-06 |
| FR2216995B1 (en) | 1978-07-28 |
| FR2216995A1 (en) | 1974-09-06 |
| ATA105874A (en) | 1975-07-15 |
| AT329179B (en) | 1976-04-26 |
| NL7401782A (en) | 1974-08-16 |
| JPS49116093A (en) | 1974-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |