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FR2630114B2 - (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION - Google Patents

(PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2630114B2
FR2630114B2 FR8805130A FR8805130A FR2630114B2 FR 2630114 B2 FR2630114 B2 FR 2630114B2 FR 8805130 A FR8805130 A FR 8805130A FR 8805130 A FR8805130 A FR 8805130A FR 2630114 B2 FR2630114 B2 FR 2630114B2
Authority
FR
France
Prior art keywords
isoquinoleine
piperidinyl
tetrahydro
derivatives
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8805130A
Other languages
French (fr)
Other versions
FR2630114A2 (en
Inventor
Pascal George
Mireille Sevrin
Christian Maloizel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8711288A external-priority patent/FR2619110B1/en
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8805130A priority Critical patent/FR2630114B2/en
Priority to EP88402022A priority patent/EP0306375A1/en
Priority to IL87339A priority patent/IL87339A0/en
Priority to JP63197010A priority patent/JPH01100167A/en
Priority to FI883667A priority patent/FI883667A/en
Priority to KR1019880010015A priority patent/KR890003733A/en
Priority to AU20475/88A priority patent/AU598149B2/en
Priority to NO88883485A priority patent/NO883485L/en
Priority to DK437588A priority patent/DK437588A/en
Priority to NZ225708A priority patent/NZ225708A/en
Priority to PT8820488A priority patent/PT88204A/en
Priority to US07/228,748 priority patent/US4885302A/en
Priority to US07/400,811 priority patent/US4945096A/en
Publication of FR2630114A2 publication Critical patent/FR2630114A2/en
Publication of FR2630114B2 publication Critical patent/FR2630114B2/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8805130A 1987-08-07 1988-04-19 (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Expired - Lifetime FR2630114B2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR8805130A FR2630114B2 (en) 1987-08-07 1988-04-19 (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP88402022A EP0306375A1 (en) 1987-08-07 1988-08-03 2-[(4-Piperidinyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their use in therapy
IL87339A IL87339A0 (en) 1987-08-07 1988-08-04 2-((4-piperidyl)methyl)-1,2,3-4-tetrahydroisoquinoline derivatives,their preparation and their application in therapy
DK437588A DK437588A (en) 1987-08-07 1988-08-05 DERIVATIVES OF 2 - ((4-PIPERIDINYL) METHYL) -1,2,3,4-TETRAHYDROISOQUINOLINE FOR THERAPEUTIC USE AND PROCEDURE FOR THE PREPARATION OF SUCH DERIVATIVES
PT8820488A PT88204A (en) 1987-08-07 1988-08-05 New 2-piperidinyl:methyl-1,2,3,4-tetra:hydro-isoquinoline derivs. - with selective action on HT one A serotoninergic receptors, e.g. for treating depression and cardiovascular disease
KR1019880010015A KR890003733A (en) 1987-08-07 1988-08-05 2-[(4-piperidyl) methyl] -1,2,3,4-tetrahydro isoquinoline derivative, its use in preparation and treatment
AU20475/88A AU598149B2 (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy
NO88883485A NO883485L (en) 1987-08-07 1988-08-05 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PIPERIDINYL-ISOKINOLINE COMPOUNDS.
JP63197010A JPH01100167A (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4- tetrahydroisoquinoline derivative
NZ225708A NZ225708A (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives
FI883667A FI883667A (en) 1987-08-07 1988-08-05 2 - / (4-PIPERIDINYL) METHYL / -1,2,3,4-TETRAHYDROISOKINOLINE DERIVATIVES, DERAS FRAMSTAELLNING OCH TERAPEUTISKA ANVAENDNING.
US07/228,748 US4885302A (en) 1987-08-07 1988-08-05 2-((4-Piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy
US07/400,811 US4945096A (en) 1987-08-07 1989-08-30 Treatment of a depressive state with 2-[(4-piperidyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivates

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8711288A FR2619110B1 (en) 1987-08-07 1987-08-07 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8805130A FR2630114B2 (en) 1987-08-07 1988-04-19 (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
FR2630114A2 FR2630114A2 (en) 1989-10-20
FR2630114B2 true FR2630114B2 (en) 1990-07-20

Family

ID=26226160

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8805130A Expired - Lifetime FR2630114B2 (en) 1987-08-07 1988-04-19 (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Country Status (1)

Country Link
FR (1) FR2630114B2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670041A1 (en) * 1967-03-14 1972-03-02 American Home Prod Isoindoles and isoindolines
FR7607M (en) * 1968-04-25 1970-01-19
GB1250719A (en) * 1969-03-19 1971-10-20

Also Published As

Publication number Publication date
FR2630114A2 (en) 1989-10-20

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