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FR2577222B1 - PROCESS FOR THE PREPARATION OF 1- (3-MERCAPTO-25-METHYLPROPIONYL) -PYRROLIDINE- (25) -CARBOXYLIC ACID - Google Patents

PROCESS FOR THE PREPARATION OF 1- (3-MERCAPTO-25-METHYLPROPIONYL) -PYRROLIDINE- (25) -CARBOXYLIC ACID

Info

Publication number
FR2577222B1
FR2577222B1 FR8601839A FR8601839A FR2577222B1 FR 2577222 B1 FR2577222 B1 FR 2577222B1 FR 8601839 A FR8601839 A FR 8601839A FR 8601839 A FR8601839 A FR 8601839A FR 2577222 B1 FR2577222 B1 FR 2577222B1
Authority
FR
France
Prior art keywords
methylpropionyl
pyrrolidine
mercapto
preparation
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8601839A
Other languages
French (fr)
Other versions
FR2577222A1 (en
Inventor
Don Ki Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boryung Pharmaceutical Co Ltd
Original Assignee
Boryung Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boryung Pharmaceutical Co Ltd filed Critical Boryung Pharmaceutical Co Ltd
Publication of FR2577222A1 publication Critical patent/FR2577222A1/en
Application granted granted Critical
Publication of FR2577222B1 publication Critical patent/FR2577222B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR8601839A 1985-02-11 1986-02-11 PROCESS FOR THE PREPARATION OF 1- (3-MERCAPTO-25-METHYLPROPIONYL) -PYRROLIDINE- (25) -CARBOXYLIC ACID Expired FR2577222B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019850000850A KR870001569B1 (en) 1985-02-11 1985-02-11 Preparing process for pyrolidine derivatives

Publications (2)

Publication Number Publication Date
FR2577222A1 FR2577222A1 (en) 1986-08-14
FR2577222B1 true FR2577222B1 (en) 1987-12-24

Family

ID=19239706

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8601839A Expired FR2577222B1 (en) 1985-02-11 1986-02-11 PROCESS FOR THE PREPARATION OF 1- (3-MERCAPTO-25-METHYLPROPIONYL) -PYRROLIDINE- (25) -CARBOXYLIC ACID

Country Status (6)

Country Link
JP (1) JPS61183263A (en)
KR (1) KR870001569B1 (en)
DE (1) DE3538747A1 (en)
ES (1) ES8606269A1 (en)
FR (1) FR2577222B1 (en)
GB (1) GB2170806B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
JPH04503662A (en) * 1988-08-26 1992-07-02 セプラコア，インコーポレーテッド Derivatives and precursors of captopril and its analogs
US5237073A (en) * 1988-08-26 1993-08-17 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
KR940005014B1 (en) * 1991-11-07 1994-06-09 보령제약 주식회사 Process for producting pyrrolidine derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4192945A (en) * 1978-12-07 1980-03-11 E. R. Squibb & Sons, Inc. Process for preparing proline and homoproline derivatives
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
JPS58124764A (en) * 1982-01-20 1983-07-25 Kanegafuchi Chem Ind Co Ltd Production of optically active thiol

Also Published As

Publication number Publication date
DE3538747C2 (en) 1988-08-18
JPS61183263A (en) 1986-08-15
GB8602782D0 (en) 1986-03-12
GB2170806A (en) 1986-08-13
KR870001569B1 (en) 1987-09-04
FR2577222A1 (en) 1986-08-14
KR860006441A (en) 1986-09-11
GB2170806B (en) 1988-08-03
ES548744A0 (en) 1986-04-01
ES8606269A1 (en) 1986-04-01
DE3538747A1 (en) 1986-08-14

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Legal Events

Date Code Title Description
ST Notification of lapse