Nothing Special   »   [go: up one dir, main page]

FR2551440B1 - Aminocyclopentanes, leur procede de preparation et compositions pharmaceutiques les contenant - Google Patents

Aminocyclopentanes, leur procede de preparation et compositions pharmaceutiques les contenant

Info

Publication number
FR2551440B1
FR2551440B1 FR8413706A FR8413706A FR2551440B1 FR 2551440 B1 FR2551440 B1 FR 2551440B1 FR 8413706 A FR8413706 A FR 8413706A FR 8413706 A FR8413706 A FR 8413706A FR 2551440 B1 FR2551440 B1 FR 2551440B1
Authority
FR
France
Prior art keywords
aminocyclopentanes
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8413706A
Other languages
English (en)
Other versions
FR2551440A1 (fr
Inventor
Eric William Collington
Peter Hallett
Christopher John Wallis
Norman Frank Hayes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838323830A external-priority patent/GB8323830D0/en
Priority claimed from GB848414676A external-priority patent/GB8414676D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2551440A1 publication Critical patent/FR2551440A1/fr
Application granted granted Critical
Publication of FR2551440B1 publication Critical patent/FR2551440B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8413706A 1983-09-06 1984-09-06 Aminocyclopentanes, leur procede de preparation et compositions pharmaceutiques les contenant Expired FR2551440B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838323830A GB8323830D0 (en) 1983-09-06 1983-09-06 Carbocyclic compounds
GB848414676A GB8414676D0 (en) 1984-06-08 1984-06-08 Carbocyclic compounds

Publications (2)

Publication Number Publication Date
FR2551440A1 FR2551440A1 (fr) 1985-03-08
FR2551440B1 true FR2551440B1 (fr) 1986-12-26

Family

ID=26286823

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8413706A Expired FR2551440B1 (fr) 1983-09-06 1984-09-06 Aminocyclopentanes, leur procede de preparation et compositions pharmaceutiques les contenant

Country Status (21)

Country Link
US (1) US4613597A (fr)
KR (1) KR850002476A (fr)
AU (1) AU574711B2 (fr)
BE (1) BE900502A (fr)
CA (1) CA1234811A (fr)
CH (1) CH662350A5 (fr)
DE (1) DE3432658A1 (fr)
DK (1) DK422984A (fr)
ES (1) ES535674A0 (fr)
FI (1) FI843469A (fr)
FR (1) FR2551440B1 (fr)
GB (1) GB2146023B (fr)
GR (1) GR80294B (fr)
IL (1) IL72862A (fr)
IT (1) IT1177981B (fr)
LU (1) LU85528A1 (fr)
NL (1) NL8402713A (fr)
NO (1) NO843529L (fr)
NZ (1) NZ209447A (fr)
PT (1) PT79175B (fr)
SE (1) SE8404456L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE902450A (fr) * 1984-05-18 1985-11-18 Glaxo Group Ltd Ethers aminocyclopentyliques leur preparation et compositions pharmaceutiques les contenant.
GB2165235A (en) * 1984-09-05 1986-04-09 Glaxo Group Ltd Carbocyclic compounds
GB2165535A (en) * 1984-09-05 1986-04-16 Glaxo Group Ltd Carbocyclic compounds
GB8625326D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Medicaments
US5039673A (en) * 1987-06-22 1991-08-13 Glaxo Group Limited Aminocyclopentyl ethers and their preparation and pharmaceutical formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK290079A (da) * 1978-07-11 1980-01-12 Glaxo Group Ltd Fremgangsmaade til fremstilling af prostanoidforbindelser
GB2028805B (en) * 1978-07-11 1982-11-03 Glaxo Group Ltd Prostanoid compounds
JPS5718671A (en) * 1980-04-30 1982-01-30 Glaxo Group Ltd Aminocyclopentane alkenoic acid and esters thereof,manufacture and drug composition
GB2079281B (en) * 1980-07-04 1984-04-18 Glaxo Group Ltd Aminocyclopentanone amides and their preparation and pharmaceutical formulation
JPS57183772A (en) * 1981-04-29 1982-11-12 Glaxo Group Ltd Aminocyclopentanol acids and esters, manufacture and medicinal composition
IL67041A (en) * 1981-10-29 1988-03-31 Glaxo Group Ltd 2-aminocyclopentane alkanoic and alkenoic acid esters,process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB8422453D0 (en) 1984-10-10
ES8600241A1 (es) 1985-10-01
CA1234811A (fr) 1988-04-05
BE900502A (fr) 1985-03-05
NZ209447A (en) 1988-07-28
PT79175B (en) 1986-11-10
IL72862A (en) 1988-07-31
PT79175A (en) 1984-10-01
IT1177981B (it) 1987-09-03
IL72862A0 (en) 1984-12-31
GB2146023B (en) 1987-03-25
DK422984D0 (da) 1984-09-05
IT8448800A1 (it) 1986-03-05
FI843469A0 (fi) 1984-09-05
SE8404456L (sv) 1985-03-07
US4613597A (en) 1986-09-23
SE8404456D0 (sv) 1984-09-05
FI843469A (fi) 1985-03-07
CH662350A5 (fr) 1987-09-30
AU574711B2 (en) 1988-07-14
DK422984A (da) 1985-03-07
NL8402713A (nl) 1985-04-01
LU85528A1 (fr) 1985-04-29
AU3275384A (en) 1985-03-14
NO843529L (no) 1985-03-07
ES535674A0 (es) 1985-10-01
DE3432658A1 (de) 1985-03-21
KR850002476A (ko) 1985-05-13
GB2146023A (en) 1985-04-11
GR80294B (en) 1985-01-07
FR2551440A1 (fr) 1985-03-08
IT8448800A0 (it) 1984-09-05

Similar Documents

Publication Publication Date Title
PT77488B (fr) Procede de preparation de derives de phenyl-1-piperidino-2-propanol et de compositions pharmaceutiques les contenant
MC1390A1 (fr) Derives de pyrazolopyridazine,procede pour leur preparation et compositions pharmaceutiques les contenant
FR2471968B1 (fr) Ethers basiques, leur procede de preparation et compositions pharmaceutiques les contenant
FR2542740B1 (fr) Derives de thiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2522324B1 (fr) Pyrrole-acetamides, leur procede de preparation et composition therapeutique les contenant
BE885385A (fr) Derives de d-6-n-propylergolines, leur procede de preparation et compositions pharmaceutiques en contenant
FR2567519B1 (fr) Nouvelles isoindolinyl-alcoyl-piperazines, compositions pharmaceutiques les contenant, et leur procede de preparation
BE892552A (fr) Nouveaux amido-aminoacides, compositions pharmaceutiques les contenant et procede de preparation de ces amido-aminoacides
BE885156A (fr) Psoralenes, leur procede de preparation et compositions pharmaceutiques les contenant
FR2531708B1 (fr) Derives de la xanthine, leur procede de preparation et compositions pharmaceutiques les contenant
FR2557114B1 (fr) Nouveaux derives de la gonadoliberine, procede pour leur preparation et compositions pharmaceutiques les contenant
BE884083A (fr) Nouveaux oxime-ethers, leur procede de preparation et compositions pharmaceutiques les contenant
FR2539126B1 (fr) Derives amino-alcoyl-sulfoniques, leur procede de preparation, et compositions pharmaceutiques en renfermant
FR2526798B1 (fr) Derives de peneme, leur procede de preparation et compositions therapeutiques les contenant
FR2582835B1 (fr) Derives de la quinoleine, leur procede de preparation et compositions pharmaceutiques les contenant
FR2563519B1 (fr) Derives d'iminothiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant
BE890874A (fr) Derives de la pyrimidine, leur procede de preparation et les compositions pharmaceutiques les contenant
FR2551440B1 (fr) Aminocyclopentanes, leur procede de preparation et compositions pharmaceutiques les contenant
FR2513994B1 (fr) Tripeptides anorexigenes, procede pour leur preparation et compositions pharmaceutiques les contenant
MC1549A1 (fr) Anthracycline-glycosides,procede pour leur preparation et medicaments les contenant
BE896628A (fr) Derives de cycloalcanes, procede pour leur preparation et compositions les contenant.
PT77767B (fr) Procede de preparation de 3',5'-diarabinosides et de compositi-ons pharmaceutiques les contenant
FR2649981B1 (fr) Derives de dihydropyrimidothiazine, leur procede de preparation et compositions pharmaceutiques les contenant
FR2517672B1 (fr) Thioalcanoyl-carnitines, procede pour leur preparation et composition pharmaceutique les contenant
FR2529549B1 (fr) Oxime-ethers d'eburnane, procede pour leur preparation et compositions pharmaceutiques qui les contiennent

Legal Events

Date Code Title Description
ST Notification of lapse