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FR2400035A1 - STEROID DERIVATIVES AND THEIR USE IN RADIO-IMMUNO-TESTS - Google Patents

STEROID DERIVATIVES AND THEIR USE IN RADIO-IMMUNO-TESTS

Info

Publication number
FR2400035A1
FR2400035A1 FR7823770A FR7823770A FR2400035A1 FR 2400035 A1 FR2400035 A1 FR 2400035A1 FR 7823770 A FR7823770 A FR 7823770A FR 7823770 A FR7823770 A FR 7823770A FR 2400035 A1 FR2400035 A1 FR 2400035A1
Authority
FR
France
Prior art keywords
immuno
tests
radio
steroid derivatives
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7823770A
Other languages
French (fr)
Other versions
FR2400035B1 (en
Inventor
Jack Bernstein
Ravi K Varma
Berthold R Vogt
Frank L Weisenborn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/901,952 external-priority patent/US4230621A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2400035A1 publication Critical patent/FR2400035A1/en
Application granted granted Critical
Publication of FR2400035B1 publication Critical patent/FR2400035B1/fr
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743Steroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J19/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne la préparation de dérivés de stéroïde marqué par un radioisotope de formule :The invention relates to the preparation of steroid derivatives labeled with a radioisotope of the formula:

FR7823770A 1977-08-12 1978-08-11 STEROID DERIVATIVES AND THEIR USE IN RADIO-IMMUNO-TESTS Granted FR2400035A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82401677A 1977-08-12 1977-08-12
US05/901,952 US4230621A (en) 1978-05-01 1978-05-01 Steroid derivatives and their use in radioimmunoassays

Publications (2)

Publication Number Publication Date
FR2400035A1 true FR2400035A1 (en) 1979-03-09
FR2400035B1 FR2400035B1 (en) 1981-02-13

Family

ID=27124779

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823770A Granted FR2400035A1 (en) 1977-08-12 1978-08-11 STEROID DERIVATIVES AND THEIR USE IN RADIO-IMMUNO-TESTS

Country Status (7)

Country Link
JP (1) JPS5436247A (en)
CA (1) CA1118409A (en)
DE (1) DE2834516A1 (en)
FR (1) FR2400035A1 (en)
GB (2) GB2002385B (en)
IT (1) IT7850710A0 (en)
NL (1) NL7808393A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4323511A (en) * 1978-05-22 1982-04-06 E. R. Squibb & Sons, Inc. Steroid derivatives and their use in radioimmunoassays
US4209614A (en) * 1978-05-30 1980-06-24 E. R. Squibb & Sons, Inc. Vitamin B12 derivative suitable for radiolabeling
US4243608A (en) * 1979-05-14 1981-01-06 E. R. Squibb & Sons, Inc. 3-(4-Hydroxyphenyl)pentanedioic acid, monohydrazide, derivatives and analogs
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids
JPS58194900A (en) * 1982-05-10 1983-11-12 Shionogi & Co Ltd 4- or 6-substituted aldosterones, its preparation and method for using the same in immunoassay
JPS59228097A (en) * 1983-06-07 1984-12-21 横河電機株式会社 Paper thickness profile control apparatus
JPS61108794A (en) * 1984-08-08 1986-05-27 インパクト システムズ インコ−ポレ−テツド Thickness control apparatus and method
JP2015193545A (en) * 2014-03-31 2015-11-05 国立大学法人京都大学 2-(3-pyridinyl)-1h-benzimidazole derivative compound, and radioactive pharmaceuticals containing the same

Also Published As

Publication number Publication date
GB2002385B (en) 1982-02-24
DE2834516A1 (en) 1979-02-22
GB2027425B (en) 1982-03-03
FR2400035B1 (en) 1981-02-13
JPS5436247A (en) 1979-03-16
NL7808393A (en) 1979-02-14
GB2027425A (en) 1980-02-20
IT7850710A0 (en) 1978-08-11
CA1118409A (en) 1982-02-16
GB2002385A (en) 1979-02-21

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Legal Events

Date Code Title Description
ST Notification of lapse