Nothing Special   »   [go: up one dir, main page]

FR2383183A1 - Derives de benzodiazepine - Google Patents

Derives de benzodiazepine

Info

Publication number
FR2383183A1
FR2383183A1 FR7806983A FR7806983A FR2383183A1 FR 2383183 A1 FR2383183 A1 FR 2383183A1 FR 7806983 A FR7806983 A FR 7806983A FR 7806983 A FR7806983 A FR 7806983A FR 2383183 A1 FR2383183 A1 FR 2383183A1
Authority
FR
France
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
general formula
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7806983A
Other languages
English (en)
Other versions
FR2383183B1 (fr
Inventor
Armin Walser
Rodney Ian Fryer
Louis Benjamin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2383183A1 publication Critical patent/FR2383183A1/fr
Application granted granted Critical
Publication of FR2383183B1 publication Critical patent/FR2383183B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La présente invention concerne des composés chimiques nouveaux. Il s'agit de dérivés de benzodiazépine de formule générale :
FR7806983A 1977-03-11 1978-03-10 Derives de benzodiazepine Granted FR2383183A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,820 US4125726A (en) 1977-03-11 1977-03-11 Imidazo[1,5-a][1,4]benzodiazepines

Publications (2)

Publication Number Publication Date
FR2383183A1 true FR2383183A1 (fr) 1978-10-06
FR2383183B1 FR2383183B1 (fr) 1980-06-06

Family

ID=25108467

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7806983A Granted FR2383183A1 (fr) 1977-03-11 1978-03-10 Derives de benzodiazepine

Country Status (13)

Country Link
US (3) US4125726A (fr)
JP (1) JPS53112897A (fr)
AU (1) AU516873B2 (fr)
BE (1) BE864809A (fr)
CA (1) CA1093073A (fr)
CH (1) CH638208A5 (fr)
DE (1) DE2810476A1 (fr)
DK (1) DK108078A (fr)
FR (1) FR2383183A1 (fr)
GB (1) GB1594867A (fr)
NL (1) NL7802675A (fr)
SE (1) SE437029B (fr)
ZA (1) ZA781384B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457868A1 (fr) * 1979-05-29 1980-12-26 Hoffmann La Roche Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4280957A (en) * 1974-09-11 1981-07-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
DE2754112A1 (de) * 1977-12-05 1979-06-13 Kali Chemie Pharma Gmbh 1,4-benzodiazepinderivate, ihre salze und diese verbindungen enthaltende arzneipraeparate
US4259241A (en) * 1979-05-29 1981-03-31 Hoffmann-La Roche Inc. Process for the preparation of imidazobenzodiazepines
US4226771A (en) * 1979-07-25 1980-10-07 Hoffmann-La Roche Inc. 1,2,5-Oxadiazino[5,4-a][1,4]benzodiazepine derivatives
US4250095A (en) * 1979-07-25 1981-02-10 Hoffmann-La Roche Inc. Imidazobenzodiazepines
US4238610A (en) * 1979-12-20 1980-12-09 Hoffmann-La Roche Inc. Intermediates for the production of imidazobenzodiazepines
US4247463A (en) * 1980-04-11 1981-01-27 Hoffmann-La Roche Inc. Process for the preparation of imidazobenzodiazepines
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
DE102007035350A1 (de) * 2007-07-27 2009-01-29 Dr. Ing. H.C. F. Porsche Aktiengesellschaft Förderleitung für ein Hydrauliksystem und Hydrauliksystem
WO2018035246A1 (fr) 2016-08-16 2018-02-22 Uwm Research Foundation, Inc. Modulateurs du récepteur gaba(a) et procédés de contrôle de l'hyperréactivité des voies respiratoires et de l'inflammation dans l'asthme
JP7101177B2 (ja) 2017-01-10 2022-07-14 バイエル・アクチエンゲゼルシヤフト 有害生物防除剤としてのヘテロサイクレン誘導体
BR112019014270B1 (pt) 2017-01-10 2023-12-26 Bayer Cropscience Aktiengesellschaft Derivados de heterociclo, seus usos, formulação agroquímica, e método para controlar pragas animais
TWI820231B (zh) 2018-10-11 2023-11-01 德商拜耳廠股份有限公司 用於製備經取代咪唑衍生物之方法
BR112022026904A2 (pt) 2020-07-02 2023-01-24 Bayer Ag Derivados de heterocicleno como agentes de controle de pragas

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE839364A (fr) * 1975-08-07 1976-09-09 Derives de diazepine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852461A (en) * 1971-08-04 1974-12-03 Upjohn Co Benzodiapines used as minor tranquilizers
US3763179A (en) * 1972-05-05 1973-10-02 Upjohn Co 2-imidazol-1-yl benzophenones
ZA755418B (en) 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
US3910946A (en) * 1974-09-12 1975-10-07 Upjohn Co 4H-Imidazo{8 1,2-a{9 {8 1,4{9 benzodiazepines
US4005099A (en) * 1975-11-21 1977-01-25 The Upjohn Company 1-[(Dimethylamino)-methyl]-6-aryl-4H-imidazo[1,5-a][1,4]benzodiazepines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE839364A (fr) * 1975-08-07 1976-09-09 Derives de diazepine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457868A1 (fr) * 1979-05-29 1980-12-26 Hoffmann La Roche Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques

Also Published As

Publication number Publication date
BE864809A (fr) 1978-09-13
FR2383183B1 (fr) 1980-06-06
US4146722A (en) 1979-03-27
CA1093073A (fr) 1981-01-06
CH638208A5 (de) 1983-09-15
AU516873B2 (en) 1981-06-25
SE7802787L (sv) 1978-09-12
SE437029B (sv) 1985-02-04
DE2810476A1 (de) 1978-09-14
US4125726A (en) 1978-11-14
DK108078A (da) 1978-09-12
ZA781384B (en) 1979-02-28
US4147875A (en) 1979-04-03
NL7802675A (nl) 1978-09-13
AU3405678A (en) 1979-09-13
JPS53112897A (en) 1978-10-02
GB1594867A (en) 1981-08-05

Similar Documents

Publication Publication Date Title
FR2403340A1 (fr) Derives imidazoliques utiles comme medicaments
FR2378001A1 (fr) Nouveaux cyclohexylcyclohexanes utiles comme derives cristallins liquides
FR2383171A1 (fr) Derives de thiopropanoylaminoacides utiles comme hypotenseurs
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FR2383183A1 (fr) Derives de benzodiazepine
FR2389629A1 (fr)
FR2416892A1 (fr) Derives de pyrido(1,2-a)pyrimidines, procede pour leur preparation et compositions pharmaceutiques qui les contiennent
FR2365567A1 (fr) Nouvelles piperazinylpyridines utiles comme medicaments
FR2391179A1 (fr) Nouveaux composes utiles comme intermediaires de synthese de la vitamine e
FR2383931A1 (fr) Derives d'oxadiazolopyrimidine
FR2392958A1 (fr) Nouveaux amino-acides fluores utiles comme medicament
FR2400008A1 (fr) Agents anti-hypertensifs
FR2374291A1 (fr)
FR2359111A1 (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques utiles comme herbicides
FR2422676A1 (fr) Complexes catalytiques de phosphorines metalliques
FR2356657A1 (fr) Nouveaux derives phospholipidiques de prostaglandines et leur procede de preparation
FR2383941A1 (fr) Nouveaux derives pyrimidinyliques et leur procede de preparation
FR2384770A1 (fr) Nouveaux derives de quinazoline utiles comme medicaments
FR2426688A1 (fr) Nouvelles neplanocines antibiotiques
FR2377382A1 (fr) Nouveaux phenylazacycloalcanes utiles comme medicaments
FR2389631A1 (fr)
FR2359116A1 (fr) N-alkyldiphenylamines
FR2389615A1 (fr)
FR2393000A1 (fr) Nouveaux derives acyles d'acides 3-cephem-4-carboxyliques utiles comme medicaments
FR2355823A1 (fr) Derives isoindoliques

Legal Events

Date Code Title Description
ST Notification of lapse