FR2187312A1 - Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan - Google Patents
Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxanInfo
- Publication number
- FR2187312A1 FR2187312A1 FR7220126A FR7220126A FR2187312A1 FR 2187312 A1 FR2187312 A1 FR 2187312A1 FR 7220126 A FR7220126 A FR 7220126A FR 7220126 A FR7220126 A FR 7220126A FR 2187312 A1 FR2187312 A1 FR 2187312A1
- Authority
- FR
- France
- Prior art keywords
- prepd
- rapidly
- recrystallization
- paracetamol
- aqueous dioxan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Detergent Compositions (AREA)
Abstract
Rapidly soluble paracetamol, esp. for use in effervescent compsns. also contg. chlorpheniramine maleate and ascorbic acid, is prepd. by dissolving paracetamol in aqueous dioxan at about 95 degrees C, cooling with rapid stirring, and collecting the fine crystals.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7220126A FR2187312A1 (en) | 1972-06-05 | 1972-06-05 | Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7220126A FR2187312A1 (en) | 1972-06-05 | 1972-06-05 | Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2187312A1 true FR2187312A1 (en) | 1974-01-18 |
FR2187312B1 FR2187312B1 (en) | 1976-03-05 |
Family
ID=9099681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7220126A Granted FR2187312A1 (en) | 1972-06-05 | 1972-06-05 | Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2187312A1 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0011489A1 (en) * | 1978-11-16 | 1980-05-28 | Beecham Group Plc | An analgesic effervescent powder and process for its preparation |
FR2586561A1 (en) * | 1985-09-05 | 1987-03-06 | Rhone Poulenc Sante | PROCESS FOR THE PREPARATION OF PARACETAMOL SPHERICAL AGGLOMERATES AND PRODUCTS OBTAINED |
FR2672212A1 (en) * | 1991-02-04 | 1992-08-07 | Lille Ii Universite | Paracetamol crystals for direct tabletting, process for preparing these crystals and tablet obtained with these crystals |
WO2023219592A3 (en) * | 2022-05-09 | 2024-03-14 | Atabay Kimya Sanayi Ve Tic. A.S. | A tablet composition comprising paracetamol, chlorpheniramine and ascorbic acid |
-
1972
- 1972-06-05 FR FR7220126A patent/FR2187312A1/en active Granted
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0011489A1 (en) * | 1978-11-16 | 1980-05-28 | Beecham Group Plc | An analgesic effervescent powder and process for its preparation |
FR2586561A1 (en) * | 1985-09-05 | 1987-03-06 | Rhone Poulenc Sante | PROCESS FOR THE PREPARATION OF PARACETAMOL SPHERICAL AGGLOMERATES AND PRODUCTS OBTAINED |
EP0219377A1 (en) * | 1985-09-05 | 1987-04-22 | Rhone-Poulenc Sante | Process for the preparation of spherical paracetamol agglomerates and products obtained thereby |
FR2672212A1 (en) * | 1991-02-04 | 1992-08-07 | Lille Ii Universite | Paracetamol crystals for direct tabletting, process for preparing these crystals and tablet obtained with these crystals |
WO2023219592A3 (en) * | 2022-05-09 | 2024-03-14 | Atabay Kimya Sanayi Ve Tic. A.S. | A tablet composition comprising paracetamol, chlorpheniramine and ascorbic acid |
Also Published As
Publication number | Publication date |
---|---|
FR2187312B1 (en) | 1976-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |