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FI973120A0 - Ihmisen gp39:n eri epitoopeille spesifisiä monoklonaalisia vasta-aineita ja menetelmiä niiden käyttämiseksi diagnosoinnissa ja terapiassa - Google Patents

Ihmisen gp39:n eri epitoopeille spesifisiä monoklonaalisia vasta-aineita ja menetelmiä niiden käyttämiseksi diagnosoinnissa ja terapiassa

Info

Publication number
FI973120A0
FI973120A0 FI973120A FI973120A FI973120A0 FI 973120 A0 FI973120 A0 FI 973120A0 FI 973120 A FI973120 A FI 973120A FI 973120 A FI973120 A FI 973120A FI 973120 A0 FI973120 A0 FI 973120A0
Authority
FI
Finland
Prior art keywords
antibodies
bind
epitopes
monoclonal antibodies
present
Prior art date
Application number
FI973120A
Other languages
English (en)
Swedish (sv)
Other versions
FI973120A (fi
Inventor
Anthony W Siadak
Diane L Hollenbaugh
Lisa K Gilliland
Marcia L Gordon
Jurgen Bajorath
Alejandro A Aruffo
Linda J Harris
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI973120A0 publication Critical patent/FI973120A0/fi
Publication of FI973120A publication Critical patent/FI973120A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI973120A 1995-01-26 1997-07-25 Ihmisen gp39:n eri epitoopeille spesifisiä monoklonaalisia vasta-aineita ja menetelmiä niiden käyttämiseksi diagnosoinnissa ja terapiassa FI973120A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/379,057 US5876950A (en) 1995-01-26 1995-01-26 Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy
PCT/US1996/001119 WO1996023071A2 (en) 1995-01-26 1996-01-26 MONOCLONAL ANTIBODIES SPECIFIC FOR DIFFERENT EPITOPES OF HUMAN gp39 AND METHODS FOR THEIR USE IN DIAGNOSIS AND THERAPY

Publications (2)

Publication Number Publication Date
FI973120A0 true FI973120A0 (fi) 1997-07-25
FI973120A FI973120A (fi) 1997-07-25

Family

ID=23495642

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973120A FI973120A (fi) 1995-01-26 1997-07-25 Ihmisen gp39:n eri epitoopeille spesifisiä monoklonaalisia vasta-aineita ja menetelmiä niiden käyttämiseksi diagnosoinnissa ja terapiassa

Country Status (15)

Country Link
US (1) US5876950A (fi)
EP (2) EP1728864B1 (fi)
JP (1) JPH10513348A (fi)
AU (1) AU692074B2 (fi)
CA (1) CA2210419A1 (fi)
CZ (1) CZ233997A3 (fi)
ES (1) ES2391101T3 (fi)
FI (1) FI973120A (fi)
HU (1) HUP9802401A3 (fi)
IL (1) IL116882A (fi)
MX (1) MX9705610A (fi)
NO (1) NO973447L (fi)
NZ (1) NZ303375A (fi)
PL (1) PL182868B1 (fi)
WO (1) WO1996023071A2 (fi)

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US6440418B1 (en) 1995-11-07 2002-08-27 Idec Pharmaceuticals Corporation Methods of treating autoimmune diseases with gp39-specific antibodies
US6340459B1 (en) 1995-12-01 2002-01-22 The Trustees Of Columbia University In The City Of New York Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients
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CN108367004B (zh) 2015-09-21 2022-09-13 阿帕特夫研究和发展有限公司 Cd3结合多肽
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CN108484761B (zh) * 2018-03-10 2021-04-30 吉林大学 一种特异性识别并诱导Aβ42的寡聚体及原纤维解聚的单链抗体、单链抗体基因及其应用
CN115141279A (zh) * 2018-09-26 2022-10-04 福州拓新天成生物科技有限公司 抗b7-h3的单克隆抗体及其在细胞治疗中的应用
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Also Published As

Publication number Publication date
HUP9802401A3 (en) 2003-03-28
PL323565A1 (en) 1998-04-14
ES2391101T3 (es) 2012-11-21
CA2210419A1 (en) 1996-08-01
NO973447L (no) 1997-09-26
PL182868B1 (pl) 2002-03-29
WO1996023071A2 (en) 1996-08-01
IL116882A (en) 2001-09-13
US5876950A (en) 1999-03-02
AU4966996A (en) 1996-08-14
WO1996023071A3 (en) 1996-09-26
NZ303375A (en) 2000-01-28
HUP9802401A2 (hu) 1999-01-28
AU692074B2 (en) 1998-05-28
MX9705610A (es) 1997-10-31
JPH10513348A (ja) 1998-12-22
CZ233997A3 (en) 1997-11-12
EP0807175A2 (en) 1997-11-19
EP1728864B1 (en) 2012-08-01
NO973447D0 (no) 1997-07-25
FI973120A (fi) 1997-07-25
EP1728864A1 (en) 2006-12-06
IL116882A0 (en) 1996-05-14

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