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FI952658A - With L-selectin reactive humanized antibodies - Google Patents

With L-selectin reactive humanized antibodies Download PDF

Info

Publication number
FI952658A
FI952658A FI952658A FI952658A FI952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A
Authority
FI
Finland
Prior art keywords
humanized antibodies
selectin
reactive humanized
selectin reactive
reactive
Prior art date
Application number
FI952658A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI952658A0 (en
Inventor
Man Sung Co
Original Assignee
Protein Design Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Design Labs Inc filed Critical Protein Design Labs Inc
Publication of FI952658A publication Critical patent/FI952658A/en
Publication of FI952658A0 publication Critical patent/FI952658A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI952658A 1992-12-01 1995-05-31 With L-selectin reactive humanized antibodies FI952658A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98394692A 1992-12-01 1992-12-01
PCT/US1993/011612 WO1994012215A1 (en) 1992-12-01 1993-11-30 Humanized antibodies reactive with l-selectin

Publications (2)

Publication Number Publication Date
FI952658A true FI952658A (en) 1995-05-31
FI952658A0 FI952658A0 (en) 1995-05-31

Family

ID=25530200

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952658A FI952658A0 (en) 1992-12-01 1995-05-31 With L-selectin reactive humanized antibodies

Country Status (12)

Country Link
EP (1) EP0671951A4 (en)
JP (1) JPH08503617A (en)
KR (1) KR100371784B1 (en)
AU (1) AU689090B2 (en)
CA (1) CA2149025A1 (en)
CZ (1) CZ140195A3 (en)
FI (1) FI952658A0 (en)
HU (1) HUT71790A (en)
NO (1) NO952160L (en)
PL (1) PL309249A1 (en)
RU (1) RU2151612C1 (en)
WO (1) WO1994012215A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
WO1996040942A1 (en) * 1995-06-07 1996-12-19 Cytel Corporation Humanized antibodies to e-selectin
AU746888B2 (en) * 1995-08-17 2002-05-02 Protein Design Labs, Inc. Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage
ATE265861T1 (en) * 1995-08-17 2004-05-15 Protein Design Labs Inc ANTIBODIES AGAINST L-SELECTIN TO PREVENT MULTIPLE ORGAN FAILURE AND ACUTE ORGAN DAMAGE
DE69737562T2 (en) * 1996-09-27 2007-12-27 The Trustees Of Columbia University In The City Of New York TREATING AN ISCHEMIC DISORDER AND IMPROVING THE INFINE RESULT
US8128963B2 (en) 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
EP0852951A1 (en) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stable lyophilized monoclonal or polyclonal antibodies containing pharmaceuticals
WO1999043353A2 (en) * 1998-02-26 1999-09-02 Boehringer Ingelheim Pharmaceuticals, Inc. Combination anti-selectin and immunosuppressant therapy
US20020029391A1 (en) * 1998-04-15 2002-03-07 Claude Geoffrey Davis Epitope-driven human antibody production and gene expression profiling
MY148646A (en) * 2004-05-10 2013-05-15 Abgenomics Cooperatief Ua Anti-psgl-1 antibodies
EP4342995A3 (en) 2006-03-31 2024-05-15 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
RU2511406C2 (en) 2006-06-08 2014-04-10 Чугаи Сейяку Кабусики Кайся Preventive and therapeutic agent for inflammatory disease
RU2510400C9 (en) 2007-09-26 2014-07-20 Чугаи Сейяку Кабусики Кайся Modification method of isoelectric point of antibody by means of amino-acid replacements in cdr
PE20090711A1 (en) 2007-09-26 2009-07-15 Chugai Pharmaceutical Co Ltd CONSTANT REGION OF MUTANT ANTIBODY
ES2585480T3 (en) 2007-12-05 2016-10-06 Chugai Seiyaku Kabushiki Kaisha Anti-NR10 antibody and use thereof
RU2596397C2 (en) 2007-12-05 2016-09-10 Чугаи Сейяку Кабусики Кайся Therapeutic agent for itching
KR102051275B1 (en) 2008-04-11 2019-12-04 추가이 세이야쿠 가부시키가이샤 Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
KR20160062207A (en) * 2008-12-05 2016-06-01 추가이 세이야쿠 가부시키가이샤 Anti-NR10 antibody and use thereof
JP2010210772A (en) * 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd Method of manufacturing liquid crystal display device
JP5717624B2 (en) 2009-03-19 2015-05-13 中外製薬株式会社 Antibody constant region variants
TWI682995B (en) 2009-03-19 2020-01-21 日商中外製藥股份有限公司 Antibody constant region alteration
AU2011286185B2 (en) * 2010-07-26 2014-08-14 Trianni, Inc. Transgenic animals and methods of use
EP2601298B1 (en) 2010-08-02 2016-11-30 Regeneron Pharmaceuticals, Inc. Mice that make binding proteins comprising vl domains
TWI812066B (en) 2010-11-30 2023-08-11 日商中外製藥股份有限公司 Antibody having calcium-dependent antigen-binding ability
WO2012088265A1 (en) * 2010-12-21 2012-06-28 Selexys Pharmaceuticals Corporation Anti-p-selectin antibodies and methods of their use and identification
RS64280B1 (en) 2011-02-25 2023-07-31 Regeneron Pharma Adam6 mice
DK3865581T3 (en) 2011-08-05 2024-10-21 Regeneron Pharma Humanized, universal light chain mice
ES2720186T3 (en) 2011-12-20 2019-07-18 Regeneron Pharma Mice with humanized light chains
AU2013204582B2 (en) 2012-06-12 2016-01-14 Regeneron Pharmaceuticals, Inc. Humanized non-human animals with restricted immunoglobulin heavy chain loci
RU2016141123A (en) 2014-03-21 2018-04-23 Регенерон Фармасьютикалз, Инк. VL ANTIGEN-BINDING PROTEINS MANIFESTING VARIOUS BINDING CHARACTERISTICS
CA2942697A1 (en) 2014-03-21 2015-09-24 Lynn Macdonald Non-human animals that make single domain binding proteins
CA2979702A1 (en) 2015-03-19 2016-09-22 Regeneron Pharmaceuticals, Inc. Non-human animals that select for light chain variable regions that bind antigen
MX2017013141A (en) 2015-04-14 2018-02-21 Chugai Pharmaceutical Co Ltd Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient.
CN114728064A (en) 2019-11-20 2022-07-08 中外制药株式会社 Antibody-containing preparation
WO2024194605A1 (en) 2023-03-17 2024-09-26 Quell Therapeutics Limited Treg therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
NZ236792A (en) * 1990-01-19 1993-05-26 Merck & Co Inc Recombinant human anti-cd18 antibody, murine 1b4 heavy or light chain variable region, dna, vectors, mammalian host and pharmaceutical compositions

Also Published As

Publication number Publication date
AU5732794A (en) 1994-06-22
CA2149025A1 (en) 1994-06-09
NO952160L (en) 1995-07-31
EP0671951A1 (en) 1995-09-20
CZ140195A3 (en) 1996-06-12
PL309249A1 (en) 1995-10-02
KR100371784B1 (en) 2003-07-22
WO1994012215A1 (en) 1994-06-09
AU689090B2 (en) 1998-03-26
HU9501564D0 (en) 1995-07-28
FI952658A0 (en) 1995-05-31
NO952160D0 (en) 1995-05-31
JPH08503617A (en) 1996-04-23
EP0671951A4 (en) 1997-05-21
HUT71790A (en) 1996-02-28
RU2151612C1 (en) 2000-06-27

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