FI872220A - Imidazokinolinyleterderivat. - Google Patents

Imidazokinolinyleterderivat. Download PDF

Info

Publication number: FI872220A
Authority: FI; Finland
Prior art keywords: imidazokinolinyleterderivat
Prior art date: 1986-05-23

Application number

FI872220A

Other languages

English (en)

Other versions

FI872220A0 (fi

FI86723B (fi

FI86723C (fi

Inventor

Nicholas A Meanwell

John J Wright

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-23

Filing date

1987-05-20

Publication date

1987-11-24

1987-05-20 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-05-20 Publication of FI872220A0 publication Critical patent/FI872220A0/fi

1987-11-24 Publication of FI872220A publication Critical patent/FI872220A/fi

1992-06-30 Publication of FI86723B publication Critical patent/FI86723B/fi

1992-10-12 Application granted granted Critical

1992-10-12 Publication of FI86723C publication Critical patent/FI86723C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI872220A 1986-05-23 1987-05-20 Foerfarande foer framstaellning av terapeutiskt anvaendbara 2,3-dihydro-2-oxo-1h-imidazo/4,5-b/kinolinyleterderivat FI86723C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/866,813 US4775674A (en)	1986-05-23	1986-05-23	Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US86681386		1986-05-23

Publications (4)

Publication Number	Publication Date
FI872220A0 FI872220A0 (fi)	1987-05-20
FI872220A true FI872220A (fi)	1987-11-24
FI86723B FI86723B (fi)	1992-06-30
FI86723C FI86723C (fi)	1992-10-12

Family

ID=25348473

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI872220A FI86723C (fi)	1986-05-23	1987-05-20	Foerfarande foer framstaellning av terapeutiskt anvaendbara 2,3-dihydro-2-oxo-1h-imidazo/4,5-b/kinolinyleterderivat

Country Status (24)

Country	Link
US (1)	US4775674A (fi)
JP (1)	JPS62283972A (fi)
KR (1)	KR900008567B1 (fi)
AT (1)	AT392790B (fi)
AU (1)	AU603577B2 (fi)
BE (1)	BE1002033A4 (fi)
CA (1)	CA1289137C (fi)
CH (1)	CH675246A5 (fi)
DE (1)	DE3717291A1 (fi)
DK (1)	DK166084C (fi)
ES (1)	ES2005588A6 (fi)
FI (1)	FI86723C (fi)
FR (1)	FR2603586B1 (fi)
GB (1)	GB2190676B (fi)
GR (1)	GR870803B (fi)
HU (1)	HU197570B (fi)
IL (1)	IL82612A0 (fi)
IT (1)	IT1205031B (fi)
LU (1)	LU86896A1 (fi)
NL (1)	NL8701226A (fi)
NZ (1)	NZ220345A (fi)
PT (1)	PT84938B (fi)
SE (1)	SE465163B (fi)
ZA (1)	ZA873583B (fi)

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* Cited by examiner, † Cited by third party
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CA1306260C (en) *	1985-10-18	1992-08-11	Shionogi & Co., Ltd.	Condensed imidazopyridine derivatives
JPH01189791A (ja) *	1988-01-26	1989-07-28	New Japan Radio Co Ltd	非接触ｉｄカード
US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
US5262540A (en) *	1989-12-20	1993-11-16	Bristol-Myers Squibb Company	[2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters
PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5208237A (en) *	1992-04-03	1993-05-04	Bristol-Meyers Squibb Company	7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5348960A (en) *	1992-04-03	1994-09-20	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5187188A (en) *	1992-04-03	1993-02-16	Bristol-Myers Squibb Company	Oxazole carboxylic acid derivatives
US5196428A (en) *	1992-04-03	1993-03-23	Bristol-Myers Squibb Company	Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5158958A (en) *	1992-04-03	1992-10-27	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5552267A (en) *	1992-04-03	1996-09-03	The Trustees Of Columbia University In The City Of New York	Solution for prolonged organ preservation
TW593317B (en)	1993-06-21	2004-06-21	Janssen Pharmaceutica Nv	Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
US6541485B1 (en)	1999-06-10	2003-04-01	3M Innovative Properties Company	Urea substituted imidazoquinolines
US6331539B1 (en) *	1999-06-10	2001-12-18	3M Innovative Properties Company	Sulfonamide and sulfamide substituted imidazoquinolines
US6573273B1 (en)	1999-06-10	2003-06-03	3M Innovative Properties Company	Urea substituted imidazoquinolines
US6756382B2 (en)	1999-06-10	2004-06-29	3M Innovative Properties Company	Amide substituted imidazoquinolines
JP4767429B2 (ja) *	2001-03-02	2011-09-07	株式会社クラレ	架橋剤および架橋性重合体
JP2006509790A (ja) *	2002-11-27	2006-03-23	アルテシアンセラピューティック，インコーポレイティド	心不全の治療のための混合されたＰＤＥ阻害およびβアドレナリン拮抗薬活性または部分的作用薬活性を有する化合物
MXPA06001669A (es)	2003-08-12	2006-04-28	3M Innovative Properties Co	Compuestos que contienen imidazo-oxima sustituidos.
PH12006500401A1 (en)	2003-08-27	2005-03-10	3M Innovative Properties Company	Aryloxy and arylalkyleneoxy substituted imidazoquinolines
US20050054665A1 (en)	2003-09-05	2005-03-10	3M Innovative Properties Company	Treatment for CD5+ B cell lymphoma
US7544697B2 (en)	2003-10-03	2009-06-09	Coley Pharmaceutical Group, Inc.	Pyrazolopyridines and analogs thereof
CN1897948A (zh)	2003-10-03	2007-01-17	3M创新有限公司	烷氧基取代的咪唑并喹啉
CA2545825A1 (en)	2003-11-14	2005-06-02	3M Innovative Properties Company	Hydroxylamine substituted imidazo ring compounds
JP2007511527A (ja)	2003-11-14	2007-05-10	スリーエムイノベイティブプロパティズカンパニー	オキシム置換イミダゾ環化合物
NZ547467A (en)	2003-11-25	2010-06-25	3M Innovative Properties Co	Substituted imidazo ring system and methods
JP2007517035A (ja)	2003-12-29	2007-06-28	スリーエムイノベイティブプロパティズカンパニー	アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン
WO2005066169A2 (en)	2003-12-30	2005-07-21	3M Innovative Properties Company	Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
US8697873B2 (en)	2004-03-24	2014-04-15	3M Innovative Properties Company	Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en)	2004-06-15	2011-09-13	3M Innovative Properties Company	Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006009826A1 (en)	2004-06-18	2006-01-26	3M Innovative Properties Company	Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7915281B2 (en)	2004-06-18	2011-03-29	3M Innovative Properties Company	Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
US7897609B2 (en)	2004-06-18	2011-03-01	3M Innovative Properties Company	Aryl substituted imidazonaphthyridines
WO2006083440A2 (en)	2004-12-30	2006-08-10	3M Innovative Properties Company	Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
JP5543068B2 (ja)	2004-12-30	2014-07-09	スリーエムイノベイティブプロパティズカンパニー	キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
JP2008530022A (ja)	2005-02-04	2008-08-07	コーリーファーマシューティカルグループ，インコーポレイテッド	免疫反応調節物質を含む水性ゲル処方物
EP1846405A2 (en)	2005-02-11	2007-10-24	3M Innovative Properties Company	Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
JP2008538550A (ja)	2005-04-01	2008-10-30	コーリーファーマシューティカルグループ，インコーポレイテッド	ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物
AU2006232377A1 (en)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Pyrazolopyridine-1,4-diamines and analogs thereof
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
WO2007025177A2 (en)	2005-08-26	2007-03-01	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
AU2006304787A1 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US7678808B2 (en)	2006-05-09	2010-03-16	Braincells, Inc.	5 HT receptor mediated neurogenesis
EP2377531A2 (en)	2006-05-09	2011-10-19	Braincells, Inc.	Neurogenesis by modulating angiotensin
WO2008008432A2 (en)	2006-07-12	2008-01-17	Coley Pharmaceutical Group, Inc.	Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en)	2006-08-01	2012-07-24	Cytokinetics, Inc.	Modulating skeletal muscle
US8299248B2 (en)	2006-08-02	2012-10-30	Cytokinetics, Incorporated	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
EP2995619B1 (en)	2006-08-02	2019-09-25	Cytokinetics, Inc.	Certain chemical entities comprising imidazopyrimidines, compositions and methods
MX2009002496A (es)	2006-09-08	2009-07-10	Braincells Inc	Combinaciones que contienen un derivado de 4-acilaminopiridina.
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US7851484B2 (en)	2007-03-30	2010-12-14	Cytokinetics, Inc.	Certain chemical entities, compositions, and methods
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
BR112014000742A2 (pt)	2011-07-13	2016-08-23	Andrew A Wolff	terapia de combinação de als
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
WO2024149378A1 (zh) *	2023-01-13	2024-07-18	上海超阳药业有限公司	喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (8)

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Publication number	Priority date	Publication date	Assignee	Title
US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
NL7807507A (nl) *	1977-07-25	1979-01-29	Hoffmann La Roche	Tricyclische verbindingen.
IL62402A0 (en) *	1980-03-24	1981-05-20	Sterling Drug Inc	Imidazo(4,5-b)pyridines,their preparation and pharmaceutical compositions containing them
US4490371A (en) *	1983-02-16	1984-12-25	Syntex (U.S.A.) Inc.	N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
JPS604186A (ja) *	1983-06-21	1985-01-10	Dai Ichi Seiyaku Co Ltd	イミダゾキナゾリン化合物
JPS6028979A (ja) *	1983-07-14	1985-02-14	Dai Ichi Seiyaku Co Ltd	イミダゾキナゾリン類化合物
FI81578C (fi) *	1984-02-15	1990-11-12	Syntex Inc	Foerfarande foer framstaellning av nya fosfodiesterasinhibierande 1,2,3,5-tetrahydroimidazo/2,1-b/ kinazolinderivat.
US4668686A (en) *	1985-04-25	1987-05-26	Bristol-Myers Company	Imidazoquinoline antithrombrogenic cardiotonic agents

1986
- 1986-05-23 US US06/866,813 patent/US4775674A/en not_active Expired - Fee Related
1987
- 1987-05-15 AU AU72993/87A patent/AU603577B2/en not_active Ceased
- 1987-05-18 NZ NZ220345A patent/NZ220345A/xx unknown
- 1987-05-19 GB GB8711839A patent/GB2190676B/en not_active Expired - Fee Related
- 1987-05-19 ZA ZA873583A patent/ZA873583B/xx unknown
- 1987-05-20 FI FI872220A patent/FI86723C/fi not_active IP Right Cessation
- 1987-05-21 GR GR870803A patent/GR870803B/el unknown
- 1987-05-21 IL IL82612A patent/IL82612A0/xx not_active IP Right Cessation
- 1987-05-22 DE DE19873717291 patent/DE3717291A1/de not_active Withdrawn
- 1987-05-22 JP JP62125642A patent/JPS62283972A/ja active Pending
- 1987-05-22 KR KR1019870005066A patent/KR900008567B1/ko not_active IP Right Cessation
- 1987-05-22 SE SE8702158A patent/SE465163B/sv not_active IP Right Cessation
- 1987-05-22 NL NL8701226A patent/NL8701226A/nl not_active Application Discontinuation
- 1987-05-22 FR FR878707252A patent/FR2603586B1/fr not_active Expired - Fee Related
- 1987-05-22 ES ES8701506A patent/ES2005588A6/es not_active Expired
- 1987-05-22 PT PT84938A patent/PT84938B/pt unknown
- 1987-05-22 BE BE8700581A patent/BE1002033A4/fr not_active IP Right Cessation
- 1987-05-22 DK DK263587A patent/DK166084C/da active
- 1987-05-22 AT AT1320/87A patent/AT392790B/de not_active IP Right Cessation
- 1987-05-22 IT IT20650/87A patent/IT1205031B/it active
- 1987-05-22 LU LU86896A patent/LU86896A1/fr unknown
- 1987-05-22 HU HU872295A patent/HU197570B/hu not_active IP Right Cessation
- 1987-05-22 CA CA000537720A patent/CA1289137C/en not_active Expired - Fee Related
- 1987-05-25 CH CH2018/87A patent/CH675246A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3717291A1 (de)	1987-11-26
BE1002033A4 (fr)	1990-05-29
GB2190676B (en)	1990-05-30
AT392790B (de)	1991-06-10
SE8702158L (sv)	1987-11-24
IT1205031B (it)	1989-03-10
ES2005588A6 (es)	1989-03-16
PT84938B (pt)	1990-02-08
IT8720650A0 (it)	1987-05-22
GR870803B (en)	1987-09-24
HU197570B (en)	1989-04-28
KR900008567B1 (ko)	1990-11-24
FI872220A0 (fi)	1987-05-20
FI86723B (fi)	1992-06-30
NL8701226A (nl)	1987-12-16
DK263587A (da)	1987-11-24
FI86723C (fi)	1992-10-12
SE8702158D0 (sv)	1987-05-22
FR2603586A1 (fr)	1988-03-11
FR2603586B1 (fr)	1990-12-28
GB8711839D0 (en)	1987-06-24
CH675246A5 (fi)	1990-09-14
DK263587D0 (da)	1987-05-22
JPS62283972A (ja)	1987-12-09
AU603577B2 (en)	1990-11-22
IL82612A0 (en)	1987-11-30
US4775674A (en)	1988-10-04
ZA873583B (en)	1988-04-27
PT84938A (en)	1987-06-01
CA1289137C (en)	1991-09-17
SE465163B (sv)	1991-08-05
DK166084B (da)	1993-03-08
ATA132087A (de)	1990-11-15
KR870011137A (ko)	1987-12-21
AU7299387A (en)	1987-11-26
LU86896A1 (fr)	1988-01-20
HUT43602A (en)	1987-11-30
DK166084C (da)	1993-08-02
GB2190676A (en)	1987-11-25
NZ220345A (en)	1990-10-26

Publication	Publication Date	Title
DE3774909D1 (de)	1992-01-16	Antitumormittel.
DE3775679D1 (de)	1992-02-13	Vernebler.
DE3767169D1 (de)	1991-02-14	Sportschuh.
ATE57924T1 (de)	1990-11-15	3-aryloxy-3-substituierte-propanamine.
FI872220A0 (fi)	1987-05-20	Imidazokinolinyleterderivat.
DE3764043D1 (de)	1990-09-06	Alkylendiamine.
ATE63533T1 (de)	1991-06-15	Xylolisomerisierung.
DE3779761D1 (de)	1992-07-16	Abseilgeraet.
DE3771918D1 (de)	1991-09-12	Chinolinamide.
DE3785294D1 (de)	1993-05-13	Neigungsmesser.
DE3786679D1 (de)	1993-09-02	Schmitt-triggerschaltung.
FI891360A (fi)	1989-03-22	Vredkonstruktion.
DE3771271D1 (de)	1991-08-14	Fluorphthalimide.
FI873857A (fi)	1988-03-09	Nukleosidanaloger.
DE3779382D1 (de)	1992-07-02	3-6-diphenylpyridazine.
DE3763648D1 (de)	1990-08-16	Rollski.
FI870997A0 (fi)	1987-03-06	Mascaraapplikator.
DE3669032D1 (de)	1990-03-22	Okulopressionsgeraet.
DE3766410D1 (de)	1991-01-10	Methylalkylcyclosiloxane.
FI861938A0 (fi)	1986-05-09	Ramkonstruktion foer en borrmaskin.
DE3764485D1 (de)	1990-10-04	Polyglycidylamine.
FI860072A0 (fi)	1986-01-08	Mataranordning foer en spannmaolstork.
FI873089A (fi)	1987-07-29	Daevert.
FI73944B (fi)	1987-08-31	Rullningsanordning foer pappersbana.
ATE48604T1 (de)	1989-12-15	Sulfidoxymolybden-dialkylphosphorodithioate.

Legal Events

Date	Code	Title	Description
1994-12-13	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: BRISTOL-MYERS SQUIBB COMPANY