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FI822748A0 - Foerfarande foer framstaellning av substituerade pyridazinderivat - Google Patents

Foerfarande foer framstaellning av substituerade pyridazinderivat

Info

Publication number
FI822748A0
FI822748A0 FI822748A FI822748A FI822748A0 FI 822748 A0 FI822748 A0 FI 822748A0 FI 822748 A FI822748 A FI 822748A FI 822748 A FI822748 A FI 822748A FI 822748 A0 FI822748 A0 FI 822748A0
Authority
FI
Finland
Prior art keywords
pyrides
substitution
framework
Prior art date
Application number
FI822748A
Other languages
English (en)
Other versions
FI72969C (fi
FI72969B (fi
FI822748L (fi
Inventor
Jean-Paul Kan
Kathleen Biziere
Camille-Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI822748A0 publication Critical patent/FI822748A0/fi
Publication of FI822748L publication Critical patent/FI822748L/fi
Application granted granted Critical
Publication of FI72969B publication Critical patent/FI72969B/fi
Publication of FI72969C publication Critical patent/FI72969C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI822748A 1981-08-07 1982-08-06 Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(2-morfolinoetylamino)-5-fenylpyridazin och av dess salter. FI72969C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8115380 1981-08-07
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (4)

Publication Number Publication Date
FI822748A0 true FI822748A0 (fi) 1982-08-06
FI822748L FI822748L (fi) 1983-02-08
FI72969B FI72969B (fi) 1987-04-30
FI72969C FI72969C (fi) 1987-08-10

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
FI822748A FI72969C (fi) 1981-08-07 1982-08-06 Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(2-morfolinoetylamino)-5-fenylpyridazin och av dess salter.
FI822747A FI72968C (fi) 1981-08-07 1982-08-06 Foerfarande foer framstaellning av 3-(aminoalkylamino)pyridazinderivat med inverkan pao det centrala nervsystemet.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI822747A FI72968C (fi) 1981-08-07 1982-08-06 Foerfarande foer framstaellning av 3-(aminoalkylamino)pyridazinderivat med inverkan pao det centrala nervsystemet.

Country Status (30)

Country Link
US (1) US4508720A (fi)
EP (2) EP0072726B1 (fi)
JP (2) JPS5877868A (fi)
KR (2) KR880001624B1 (fi)
AR (2) AR231441A1 (fi)
AT (2) ATE12227T1 (fi)
AU (2) AU548930B2 (fi)
CA (2) CA1174240A (fi)
CS (2) CS229940B2 (fi)
DD (2) DD202549A5 (fi)
DE (2) DE3269383D1 (fi)
DK (2) DK148795C (fi)
EG (2) EG15747A (fi)
ES (2) ES514794A0 (fi)
FI (2) FI72969C (fi)
FR (1) FR2510998B1 (fi)
GR (2) GR76430B (fi)
HU (2) HU189166B (fi)
IE (2) IE53388B1 (fi)
IL (2) IL66408A (fi)
MA (2) MA19562A1 (fi)
NO (2) NO157861C (fi)
NZ (2) NZ201518A (fi)
OA (2) OA07176A (fi)
PH (1) PH18545A (fi)
PL (2) PL137199B1 (fi)
PT (2) PT75351B (fi)
SU (2) SU1140685A3 (fi)
YU (2) YU171882A (fi)
ZA (2) ZA825513B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
US4565814A (en) * 1983-01-28 1986-01-21 Sanofi Pyridazine derivatives having a psychotropic action and compositions
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
US5656631A (en) * 1989-02-07 1997-08-12 Sanofi Pyridazine derivatives
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
ATE420867T1 (de) * 2002-08-13 2009-01-15 Merck Sharp & Dohme Phenylpyridazin derivative als liganden für gaba- rezeptoren
ATE523199T1 (de) * 2004-11-02 2011-09-15 Univ Northwestern Pyridazinverbindungen und verfahren
CA2589106C (en) * 2004-11-02 2015-07-21 Northwestern University Pyridazine compounds, compositions and methods and their use in treating inflammatory diseases
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
AU2007243280A1 (en) 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
KR840001145A (ko) 1984-03-28
IE53388B1 (en) 1988-10-26
FI822747A0 (fi) 1982-08-06
DK148795B (da) 1985-09-30
PH18545A (en) 1985-08-09
PT75350B (fr) 1984-08-01
EP0074863B1 (fr) 1986-02-26
HU189166B (en) 1986-06-30
PL237808A1 (en) 1983-02-28
NO157861C (no) 1988-06-01
KR840001159A (ko) 1984-03-28
IE53387B1 (en) 1988-10-26
AU548931B2 (en) 1986-01-09
NO157861B (no) 1988-02-22
FI822747L (fi) 1983-02-08
AU8655382A (en) 1983-02-10
ES514795A0 (es) 1983-04-16
GR76430B (fi) 1984-08-10
DK354382A (da) 1983-02-08
PT75351A (fr) 1982-08-01
KR890001569B1 (ko) 1989-05-08
IL66408A (en) 1985-12-31
AU8655482A (en) 1983-02-10
FI72969C (fi) 1987-08-10
FI72969B (fi) 1987-04-30
NO822510L (no) 1983-02-08
HU190028B (en) 1986-08-28
OA07175A (fr) 1984-04-30
EP0072726B1 (fr) 1985-03-20
AR231441A1 (es) 1984-11-30
MA19562A1 (fr) 1983-04-01
FR2510998B1 (fr) 1986-01-10
DK148537B (da) 1985-07-29
GR76429B (fi) 1984-08-10
IE821778L (en) 1983-02-07
DK148795C (da) 1986-03-10
FI822748L (fi) 1983-02-08
DD202549A5 (de) 1983-09-21
JPS5877867A (ja) 1983-05-11
DD202715A5 (de) 1983-09-28
US4508720A (en) 1985-04-02
PT75351B (fr) 1984-08-01
YU172082A (en) 1985-03-20
EP0072726A1 (fr) 1983-02-23
ES8305738A1 (es) 1983-04-16
DE3262671D1 (en) 1985-04-25
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
CS229941B2 (en) 1984-07-16
FR2510998A1 (fr) 1983-02-11
ZA825513B (en) 1983-06-29
FI72968C (fi) 1987-08-10
ES8305737A1 (es) 1983-04-16
NZ201518A (en) 1985-04-30
AR231637A1 (es) 1985-01-31
JPS5877868A (ja) 1983-05-11
ES514794A0 (es) 1983-04-16
SU1140685A3 (ru) 1985-02-15
CS229940B2 (en) 1984-07-16
PL237809A1 (en) 1983-02-28
IE821779L (en) 1983-02-07
NO157102B (no) 1987-10-12
CA1174240A (en) 1984-09-11
EG15747A (en) 1986-06-30
OA07176A (fr) 1984-04-30
JPH0459312B2 (fi) 1992-09-21
DK148537C (da) 1986-01-13
ZA825512B (en) 1983-06-29
ATE12227T1 (de) 1985-04-15
KR880001624B1 (ko) 1988-09-02
PL130647B1 (en) 1984-08-31
NO822509L (no) 1983-02-08
MA19560A1 (fr) 1983-04-01
ATE18216T1 (de) 1986-03-15
NZ201520A (en) 1985-04-30
IL66409A0 (en) 1982-11-30
AU548930B2 (en) 1986-01-09
FI72968B (fi) 1987-04-30
IL66408A0 (en) 1982-11-30
PL137199B1 (en) 1986-05-31
PT75350A (fr) 1982-08-01
SU1138024A3 (ru) 1985-01-30
DK354482A (da) 1983-02-08
IL66409A (en) 1985-09-29
CA1179346A (en) 1984-12-11
EP0074863A1 (fr) 1983-03-23
DE3269383D1 (en) 1986-04-03
EG15788A (en) 1986-09-30

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Legal Events

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MM Patent lapsed

Owner name: SANOFI