ES415277A1 - Procedimiento de preparacion de derivados de la cisterna. - Google Patents
Procedimiento de preparacion de derivados de la cisterna.Info
- Publication number
- ES415277A1 ES415277A1 ES415277A ES415277A ES415277A1 ES 415277 A1 ES415277 A1 ES 415277A1 ES 415277 A ES415277 A ES 415277A ES 415277 A ES415277 A ES 415277A ES 415277 A1 ES415277 A1 ES 415277A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- atheromatic
- reduction
- allyl
- cysteines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001944 cysteine derivatives Chemical class 0.000 title 1
- -1 S-substituted glutathiones Chemical class 0.000 abstract 3
- ZFAHNWWNDFHPOH-YFKPBYRVSA-N S-allylcysteine Chemical compound OC(=O)[C@@H](N)CSCC=C ZFAHNWWNDFHPOH-YFKPBYRVSA-N 0.000 abstract 2
- 235000018417 cysteine Nutrition 0.000 abstract 2
- 150000001945 cysteines Chemical class 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- ZFAHNWWNDFHPOH-UHFFFAOYSA-N S-Allyl-L-cystein Natural products OC(=O)C(N)CSCC=C ZFAHNWWNDFHPOH-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical class 0.000 abstract 1
- 210000000709 aorta Anatomy 0.000 abstract 1
- 125000000490 cinnamyl group Chemical group C(C=CC1=CC=CC=C1)* 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000002350 geranyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 230000037356 lipid metabolism Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7221607A FR2187327B1 (es) | 1972-06-15 | 1972-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES415277A1 true ES415277A1 (es) | 1976-02-01 |
Family
ID=9100257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES415277A Expired ES415277A1 (es) | 1972-06-15 | 1973-05-28 | Procedimiento de preparacion de derivados de la cisterna. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3950387A (es) |
| JP (1) | JPS5239815B2 (es) |
| CA (1) | CA1019745A (es) |
| ES (1) | ES415277A1 (es) |
| FR (1) | FR2187327B1 (es) |
| GB (1) | GB1389814A (es) |
| ZA (1) | ZA733812B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002634A (en) * | 1969-09-04 | 1977-01-11 | Societe Anonyme Dite: L'oreal | N-oxypyridyl substituted cysteine or cysteine derivative thereof |
| US4105789A (en) * | 1976-05-10 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Carboxyalkylacylamino acids |
| US4160835A (en) * | 1976-11-19 | 1979-07-10 | Merck & Co., Inc. | Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid |
| US4093739A (en) * | 1977-06-15 | 1978-06-06 | Mead Johnson & Company | Mercaptoacylamidobenzoyl glycine and mucolytic process |
| ES469060A1 (es) * | 1978-04-22 | 1979-04-01 | Invest Tecnica Aplicada | Procedimiento para la preparacion de nuevos derivados tio- prenilicos con actividad farmacologica |
| LU83327A1 (fr) * | 1981-04-29 | 1983-03-24 | Midit | Procede de preparation de derives de 1,4-thiazine,leur utilisation ainsi que compositions contenant ces derives |
| US4571430A (en) * | 1982-11-08 | 1986-02-18 | Medi-Physics, Inc. | Homocysteine and homocysteinamide derivatives |
| US6030950A (en) * | 1987-07-09 | 2000-02-29 | Ohlenschlaeger; Gerhard | Pharmaceutical therapeutic use of glutathione derivative |
| GB2217706A (en) * | 1988-07-07 | 1989-11-01 | W A Gibbons | alpha -Amino-alkanoic acid derivatives and process for their preparation with anti-inflammatory, analgesic, sedative, hypnotic, anxiolytic, spasmolytic, anaesthetic, muscle relaxant and cardiovascular activity |
| US5464825A (en) * | 1991-03-14 | 1995-11-07 | Cornell Research Foundation, Inc. | Raising glutathione equivalent levels using N-acyl glutathione monoesters |
| CA2099346A1 (en) * | 1992-07-17 | 1994-01-18 | Shinji Ohmori | Lipid metabolism improving composition |
| JPH08509737A (ja) * | 1993-05-03 | 1996-10-15 | コーネル・リサーチ・ファウンデーション・インコーポレイテッド | グルタチオンジエステルの使用 |
| JP4255138B2 (ja) * | 1996-05-24 | 2009-04-15 | 湧永製薬株式会社 | 脳疾患治療剤 |
| US6492429B1 (en) * | 2000-07-10 | 2002-12-10 | N.V. Nutricia | Composition for the treatment of osteoarthritis |
| US6384078B1 (en) * | 2000-11-21 | 2002-05-07 | Arthur Vanmoor | Method of treating elevated cholesterol levels by enhancing the effectiveness of the human immune system |
| US8765817B1 (en) | 2008-12-03 | 2014-07-01 | Arrowhead Center, Inc. | Selective inhibitors of EG5 motors and methods of use |
| US8349899B1 (en) | 2008-12-03 | 2013-01-08 | Arrowhead Center, Inc. | Selective inhibitors of EG5 motors and methods of use |
| JP2013035772A (ja) * | 2011-08-05 | 2013-02-21 | Osaka City Univ | 白血球活性化抑制剤 |
| KR101511056B1 (ko) * | 2013-06-28 | 2015-04-10 | 한밭대학교 산학협력단 | 신규한 ｓ-알릴 시스테인 유도체 및 그의 용도 |
| WO2017096450A1 (en) * | 2015-12-07 | 2017-06-15 | Ems S/A | New compounds with antioxidant and antiaging activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3531490A (en) * | 1968-09-06 | 1970-09-29 | Us Agriculture | S-beta-(4-pyridylethyl)-l-cysteine |
-
1972
- 1972-06-15 FR FR7221607A patent/FR2187327B1/fr not_active Expired
-
1973
- 1973-05-28 ES ES415277A patent/ES415277A1/es not_active Expired
- 1973-06-04 CA CA173,160A patent/CA1019745A/en not_active Expired
- 1973-06-05 ZA ZA733812A patent/ZA733812B/xx unknown
- 1973-06-07 US US05/367,821 patent/US3950387A/en not_active Expired - Lifetime
- 1973-06-07 GB GB2729173A patent/GB1389814A/en not_active Expired
- 1973-06-11 JP JP48066246A patent/JPS5239815B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2187327A1 (es) | 1974-01-18 |
| CA1019745A (en) | 1977-10-25 |
| JPS504020A (es) | 1975-01-16 |
| US3950387A (en) | 1976-04-13 |
| DE2329819B2 (de) | 1977-04-07 |
| FR2187327B1 (es) | 1975-06-20 |
| GB1389814A (en) | 1975-04-09 |
| AU5677273A (en) | 1974-12-12 |
| ZA733812B (en) | 1974-04-24 |
| DE2329819A1 (de) | 1974-01-03 |
| JPS5239815B2 (es) | 1977-10-07 |
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