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ES2570856T3 - Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros - Google Patents

Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Info

Publication number
ES2570856T3
ES2570856T3 ES12173896T ES12173896T ES2570856T3 ES 2570856 T3 ES2570856 T3 ES 2570856T3 ES 12173896 T ES12173896 T ES 12173896T ES 12173896 T ES12173896 T ES 12173896T ES 2570856 T3 ES2570856 T3 ES 2570856T3
Authority
ES
Spain
Prior art keywords
polymers
compositions containing
synergistic combination
ophthalmic compositions
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES12173896T
Other languages
English (en)
Inventor
Masood A Chowhan
Huagang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33539082&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2570856(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2570856T3 publication Critical patent/ES2570856T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una composición acuosa para su uso en el tratamiento del ojo seco mediante administración oftálmica tópica, que comprende una cantidad que mejora la viscosidad de una combinación de dos polímeros que tiene un efecto sinérgico sobre la viscosidad de la composición y en donde la combinación de dos polímeros se selecciona del grupo que consiste en hidroxipropilmetilcelulosa y ácido hialurónico o hidroxietilcelulosa, en donde la concentración de hidroxipropil metilcelulosa oscila entre el 0,05-0,5 % (p/v).
ES12173896T 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros Expired - Lifetime ES2570856T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47825303P 2003-06-13 2003-06-13

Publications (1)

Publication Number Publication Date
ES2570856T3 true ES2570856T3 (es) 2016-05-20

Family

ID=33539082

Family Applications (3)

Application Number Title Priority Date Filing Date
ES11163662T Expired - Lifetime ES2410505T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
ES12173896T Expired - Lifetime ES2570856T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
ES09168920T Expired - Lifetime ES2415738T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES11163662T Expired - Lifetime ES2410505T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES09168920T Expired - Lifetime ES2415738T3 (es) 2003-06-13 2004-06-08 Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros

Country Status (16)

Country Link
US (1) US7709012B2 (es)
EP (5) EP2116227B1 (es)
JP (4) JP4860475B2 (es)
KR (5) KR101131056B1 (es)
CN (1) CN100475192C (es)
AU (2) AU2004249137B2 (es)
BR (1) BRPI0411361B1 (es)
CA (6) CA2839847C (es)
DK (1) DK2116227T3 (es)
ES (3) ES2410505T3 (es)
MX (1) MXPA05013290A (es)
PL (1) PL2116227T3 (es)
PT (1) PT2116227E (es)
SI (1) SI2116227T1 (es)
WO (1) WO2004112836A2 (es)
ZA (1) ZA200509440B (es)

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US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US8138156B2 (en) * 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
PL2109442T3 (pl) * 2007-02-09 2014-07-31 Novartis Ag Kompozycje oftalmiczne zawierające synergistyczną kombinację trzech polimerów
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
CN101784287B (zh) 2007-06-26 2013-04-24 若素制药株式会社 水性组合物
KR101529093B1 (ko) 2007-08-29 2015-06-16 와카모토 세이야꾸 가부시끼가이샤 라타노프로스트 함유 수성 의약 조성물
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US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US20100178317A1 (en) * 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
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US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
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US9867810B1 (en) 2016-08-19 2018-01-16 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
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Also Published As

Publication number Publication date
CA2839849C (en) 2017-03-07
EP2116227A3 (en) 2009-12-30
BRPI0411361A (pt) 2006-07-25
EP3028692B1 (en) 2020-04-22
KR20110032007A (ko) 2011-03-29
EP2526929B1 (en) 2016-04-06
JP2011026354A (ja) 2011-02-10
ES2415738T3 (es) 2013-07-26
SI2116227T1 (sl) 2013-07-31
KR101147046B1 (ko) 2012-05-22
CA2839898A1 (en) 2004-12-29
JP2011184463A (ja) 2011-09-22
KR101131056B1 (ko) 2012-04-23
KR20060012024A (ko) 2006-02-06
EP3028692A1 (en) 2016-06-08
AU2010200297B2 (en) 2012-04-26
DK2116227T3 (da) 2013-05-27
CA2839847C (en) 2016-03-15
CA2839930A1 (en) 2004-12-29
EP2526929A8 (en) 2013-04-10
AU2010200297A1 (en) 2010-02-18
CA2839847A1 (en) 2004-12-29
KR20110098863A (ko) 2011-09-01
CA2839928A1 (en) 2004-12-29
KR20120062846A (ko) 2012-06-14
EP2526929A1 (en) 2012-11-28
CA2839898C (en) 2017-01-24
ZA200509440B (en) 2007-04-25
CA2839930C (en) 2016-07-05
CA2527712A1 (en) 2004-12-29
KR20110134525A (ko) 2011-12-14
PT2116227E (pt) 2013-06-28
PL2116227T3 (pl) 2013-08-30
WO2004112836A8 (en) 2013-02-14
CN100475192C (zh) 2009-04-08
EP2361610A1 (en) 2011-08-31
MXPA05013290A (es) 2006-03-09
AU2004249137B2 (en) 2010-03-11
CA2839849A1 (en) 2004-12-29
JP4860475B2 (ja) 2012-01-25
EP2116227A2 (en) 2009-11-11
JP2007500244A (ja) 2007-01-11
JP2013100360A (ja) 2013-05-23
EP2361610B1 (en) 2013-04-24
AU2004249137A1 (en) 2004-12-29
ES2410505T3 (es) 2013-07-02
CN1802147A (zh) 2006-07-12
US20040253280A1 (en) 2004-12-16
US7709012B2 (en) 2010-05-04
CA2839928C (en) 2016-10-04
CA2527712C (en) 2014-08-05
EP1631257A2 (en) 2006-03-08
WO2004112836A2 (en) 2004-12-29
WO2004112836A3 (en) 2005-06-16
BRPI0411361B1 (pt) 2017-05-23
EP2116227B1 (en) 2013-04-24

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