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ES2493990T3 - Ensayos con nanoetiquetas SERS - Google Patents

Ensayos con nanoetiquetas SERS Download PDF

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Publication number
ES2493990T3
ES2493990T3 ES07763259.4T ES07763259T ES2493990T3 ES 2493990 T3 ES2493990 T3 ES 2493990T3 ES 07763259 T ES07763259 T ES 07763259T ES 2493990 T3 ES2493990 T3 ES 2493990T3
Authority
ES
Spain
Prior art keywords
nanolabel
sers
molecule
assays
magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07763259.4T
Other languages
English (en)
Inventor
Michael Natan
Sharron Gaynor Penn
Remy Cromer
Michael Sha
Hongxia Xu
William E. Doering
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2493990T3 publication Critical patent/ES2493990T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un método para detectar una molécula de interés que comprende: proporcionar una perla magnética conjugada a una molécula; hibridar la perla magnética con una diana complementaria capaz de unirse de manera selectiva a la molécula, incluyendo la diana una porción de biotina; poner en contacto la perla magnética hibridada con una nanoetiqueta SERS capaz de unirse a la porción de biotina; separar magnéticamente la perla magnética; y detectar el espectro Raman de una molécula indicadora Raman asociada con la nanoetiqueta SERS.

Description

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Claims (1)

  1. imagen1
ES07763259.4T 2006-02-08 2007-02-08 Ensayos con nanoetiquetas SERS Active ES2493990T3 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77176606P 2006-02-08 2006-02-08
US771766P 2006-02-08
US83291706P 2006-07-24 2006-07-24
US832917P 2006-07-24
US87096306P 2006-12-20 2006-12-20
US870963P 2006-12-20
PCT/US2007/061878 WO2007092941A2 (en) 2006-02-08 2007-02-08 Sers nanotag assays

Publications (1)

Publication Number Publication Date
ES2493990T3 true ES2493990T3 (es) 2014-09-12

Family

ID=38345965

Family Applications (2)

Application Number Title Priority Date Filing Date
ES07763259.4T Active ES2493990T3 (es) 2006-02-08 2007-02-08 Ensayos con nanoetiquetas SERS
ES13162214.4T Active ES2629832T3 (es) 2006-02-08 2007-02-08 Ensayos con nanoetiquetas SERS

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES13162214.4T Active ES2629832T3 (es) 2006-02-08 2007-02-08 Ensayos con nanoetiquetas SERS

Country Status (5)

Country Link
US (2) US20120164624A1 (es)
EP (3) EP3241838A1 (es)
JP (1) JP5266066B2 (es)
ES (2) ES2493990T3 (es)
WO (1) WO2007092941A2 (es)

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EP2755031B1 (en) 2007-03-20 2017-05-03 Becton, Dickinson and Company Assay using surface-enhanced raman spectroscopy (sers)-active particles
JP2010525333A (ja) * 2007-04-18 2010-07-22 ベクトン・ディキンソン・アンド・カンパニー Ｓｅｒｓナノタグを用いる分析法
EP2162710A4 (en) * 2007-06-29 2011-09-07 Becton Dickinson Co EXAMINED SURFACE RAMAN LASER SPECTROMETRY NANOMARKER ASSAYS WITH ENHANCED ASSAY KINETICS
EP2195461B1 (en) 2007-09-17 2015-05-27 Mattias Strömberg Magnetic detection of small entities
US20110065086A1 (en) * 2008-02-21 2011-03-17 Otc Biotechnologies, Llc Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays
RU2494375C2 (ru) * 2008-09-25 2013-09-27 Конинклейке Филипс Электроникс Н.В. Система и способ детектирования
US8866108B1 (en) 2009-01-26 2014-10-21 Krowker Direny Microtagging motor vehicles for identification from a paint sample discovered during a criminal investigation
GB201016484D0 (en) 2010-09-30 2010-11-17 Geneseque As Method
KR101352342B1 (ko) * 2010-11-24 2014-02-17 서울대학교산학협력단 코어 물질과 쉘 물질 사이에 나노갭이 형성된 단일 나노입자 및 이의 제조방법
WO2012078801A2 (en) * 2010-12-07 2012-06-14 Voorhees Kent J Detection of magnetic-field-concentrated analytes in a lateral flow capillary
WO2013040782A1 (en) 2011-09-22 2013-03-28 East China University Of Science And Technology Metallic nanoparticles and methods for their preparation and use
CA2869732C (en) 2012-04-12 2018-04-03 Kristin Weidemaier Methods, systems, and devices for detecting and identifying microorganisms in microbiological culture samples
CN103529011A (zh) * 2012-07-06 2014-01-22 南京大学 高灵敏拉曼光谱检测dna的一种方法
EP2892352B1 (en) 2012-08-31 2020-12-09 Sloan Kettering Institute For Cancer Research Particles, methods and uses thereof
US9512468B2 (en) * 2012-11-06 2016-12-06 Industrial Technology Research Institute Detection method uses magnetic and detectable nanoparticles with oligonucleotides attached thereto
WO2014100380A2 (en) 2012-12-19 2014-06-26 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
JP6635791B2 (ja) 2013-02-20 2020-01-29 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ 広視野ラマン撮像装置および関連方法
EP3004882B1 (en) * 2013-06-06 2018-03-21 Koninklijke Philips N.V. Reagents, methods and devices to prevent aggregation in particle based tests for the detection of multimeric target molecules
US10912947B2 (en) 2014-03-04 2021-02-09 Memorial Sloan Kettering Cancer Center Systems and methods for treatment of disease via application of mechanical force by controlled rotation of nanoparticles inside cells
WO2015171561A1 (en) 2014-05-05 2015-11-12 The Regents Of The University Of California Determining fluid reservoir connectivity using nanowire probes
CA2956210A1 (en) 2014-07-28 2016-02-04 Memorial Sloan Kettering Cancer Center Metal(loid) chalcogen nanoparticles as universal binders for medical isotopes
GB201413929D0 (en) 2014-08-06 2014-09-17 Geneseque As Method
KR101860543B1 (ko) * 2015-01-09 2018-05-24 한양대학교 에리카산학협력단 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법
CA2990223A1 (en) 2015-07-01 2017-01-05 Memorial Sloan Kettering Cancer Center Anisotropic particles, methods and uses thereof
CN106908598B (zh) * 2017-03-21 2018-11-06 南方医科大学南海医院 一种基于单壁碳纳米管的核酸适配体-悬浮芯片磁性检测微球及其制备和检测方法
CN108642164B (zh) * 2018-05-17 2021-01-08 浙江大学 miRNA捕获探针、分离扩增一体化的检测方法及检测试剂盒
JP7242391B2 (ja) * 2019-04-12 2023-03-20 富士フイルム株式会社 データ処理装置、データ処理装置の作動方法、データ処理装置の作動プログラム
CN112683874B (zh) * 2019-10-18 2023-12-15 华中师范大学 一种超容量信息编码系统及其应用
CN113649590A (zh) * 2021-08-23 2021-11-16 合肥学院 一种用于联吡啶除草剂检测的纳米银反蛋白石sers探针的制备方法
GB202115325D0 (en) * 2021-10-25 2021-12-08 Countagen Ab Method
CN117070603B (zh) * 2023-08-28 2024-09-20 海南医学院 一种用于miRNA检测的探针及其检测方法和应用
CN118421798A (zh) * 2024-05-22 2024-08-02 南通市海门区人民医院 用于检测结直肠癌相关血清生物标志物、sers传感器及制备方法

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Also Published As

Publication number Publication date
EP1981994A2 (en) 2008-10-22
EP1981994A4 (en) 2010-09-08
EP2644615A2 (en) 2013-10-02
EP2644615A3 (en) 2013-12-18
WO2007092941A2 (en) 2007-08-16
US20130337569A1 (en) 2013-12-19
JP2009525763A (ja) 2009-07-16
ES2629832T3 (es) 2017-08-16
US20120164624A1 (en) 2012-06-28
EP3241838A1 (en) 2017-11-08
JP5266066B2 (ja) 2013-08-21
WO2007092941A3 (en) 2008-10-16
EP1981994B1 (en) 2014-06-04
EP2644615B1 (en) 2017-04-05

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