Nothing Special   »   [go: up one dir, main page]

ES2164154T3 - Adsorbente de proteinas resistente a los alcalis. - Google Patents

Adsorbente de proteinas resistente a los alcalis.

Info

Publication number
ES2164154T3
ES2164154T3 ES95922058T ES95922058T ES2164154T3 ES 2164154 T3 ES2164154 T3 ES 2164154T3 ES 95922058 T ES95922058 T ES 95922058T ES 95922058 T ES95922058 T ES 95922058T ES 2164154 T3 ES2164154 T3 ES 2164154T3
Authority
ES
Spain
Prior art keywords
adsorbent
sub
alcalis
proteins
proteins resistant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95922058T
Other languages
English (en)
Inventor
Sven Oscarsson
Jerker Porath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2164154T3 publication Critical patent/ES2164154T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3253—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure not containing any of the heteroatoms nitrogen, oxygen or sulfur, e.g. aromatic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PRESENTA UN ADSORBENTE PREFERIBLEMENTE PARA PROTEINAS Y PEPTIDOS, PERO TAMBIEN PARA, POR EJEMPLO, CIERTOS METALES, CON LIGANDOS HIDROFILICOS COVALENTEMENTE UNIDOS A UNA RED DE POLIMERO ALREDEDOR DE UN PORTADOR, Y QUE TIENE LA ESTRUCTURA GENERAL: -XS-(CH{SUB, 2}){SUB, N}-R, EN DONDE X ES UN BRAZO SEPARADOR, N ES UN ENTERO ENTRE 1 O 2, Y R ES UN SISTEMA DE ANILLO RICO EN ELECTRONES {PI} CON AL MENOS UN ATOMO DE NITROGENO EN LA ESTRUCTURA DE ANILLO. GRACIAS A SU RESISTENCIA A 1 M CAUSTICO, UNA CONCENTRACION QUE ELIMINA BACTERIAS, VIRUS Y PIROGENOS, EL ADSORBENTE PUEDE REUTILIZARSE PARA PROPOSITOS MEDICOS EN TRABAJOS A GRAN ESCALA.
ES95922058T 1994-06-07 1995-06-06 Adsorbente de proteinas resistente a los alcalis. Expired - Lifetime ES2164154T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9401960A SE9401960L (sv) 1994-06-07 1994-06-07 Alkalibeständigt proteinadsorbent

Publications (1)

Publication Number Publication Date
ES2164154T3 true ES2164154T3 (es) 2002-02-16

Family

ID=20394269

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95922058T Expired - Lifetime ES2164154T3 (es) 1994-06-07 1995-06-06 Adsorbente de proteinas resistente a los alcalis.

Country Status (9)

Country Link
US (1) US5942463A (es)
EP (1) EP0764049B1 (es)
JP (1) JP3553962B2 (es)
AT (1) ATE205112T1 (es)
DE (1) DE69522564T2 (es)
DK (1) DK0764049T3 (es)
ES (1) ES2164154T3 (es)
SE (1) SE9401960L (es)
WO (1) WO1995033557A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19623131C2 (de) * 1996-06-10 2001-10-31 Gerhard Harry Scholz Konjugat, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Bindung von Substanzen
EP1386660B1 (en) 1996-08-30 2009-09-02 Upfront Chromatography A/S Isolation of immunoglobulins
SE9700769D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
CA2407276A1 (en) 2000-04-28 2001-11-08 Accurate Polymers, Ltd. Simulated activity of protein a displayed by ligands attached to a cellulose bead surface
SE0200543D0 (sv) * 2002-02-21 2002-02-21 Amersham Biosciences Ab Method of separation using aromatic thioether ligands
GB0219681D0 (en) * 2002-08-23 2002-10-02 Anglo Platinum Ltd Chromatographic medium
US8288169B2 (en) * 2005-01-21 2012-10-16 Argylla Technologies Surface mediated self-assembly of nanoparticles
US20090208919A1 (en) * 2005-01-21 2009-08-20 Argylla Technologies, Llp Particle matrix for storage of biomolecules
US7964380B2 (en) * 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
US20080220968A1 (en) * 2005-07-05 2008-09-11 Ge Healthcare Bio-Sciences Ab [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
SG144809A1 (en) 2007-01-11 2008-08-28 Millipore U K Ltd Benzimidazole compounds and their use as chromatographic ligands
EA201290076A1 (ru) * 2009-07-28 2012-08-30 Инстракцион Гмбх Специфичный сорбент для связывания белков и пептидов и способ выделения с его использованием
NZ599323A (en) * 2009-10-15 2014-06-27 Univ Monash Affinity ligands and methods for protein purification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE470099B (sv) * 1984-05-17 1993-11-08 Jerker Porath Sulfonaktiverade tioeteradsorbenter för separation av t ex protein
SE452557B (sv) * 1984-10-30 1987-12-07 Exploaterings Ab Tbf Amfipatisk gelprodukt for kromatografisk och satsvis adsorption
SE500574C2 (sv) * 1986-02-13 1994-07-18 Gel Innovation Handelsbolag Nitrilofor adsorbent för separation och immobilisering av proteiner, sätt att framställa adsorbentet, samt dess användning för fraktionering och immobilisering av biopolymerer
SE462165B (sv) * 1988-02-26 1990-05-14 Porath Jerker Saett att paa en baerare adsorbera sammansatta proteinkomplex, saerskilt vid biospecifika bestaemningsmetoder
DK52791D0 (da) * 1991-03-22 1991-03-22 Kem En Tec As Adsorptionsmatricer
US5502022A (en) * 1994-05-16 1996-03-26 Biosepra, Inc. Chromatography adsorbents utilizing mercapto heterocyclic ligands

Also Published As

Publication number Publication date
WO1995033557A1 (en) 1995-12-14
DE69522564T2 (de) 2002-09-05
JP3553962B2 (ja) 2004-08-11
DE69522564D1 (de) 2001-10-11
JPH10502862A (ja) 1998-03-17
EP0764049A1 (en) 1997-03-26
DK0764049T3 (da) 2001-12-10
ATE205112T1 (de) 2001-09-15
SE9401960D0 (sv) 1994-06-07
US5942463A (en) 1999-08-24
SE9401960L (sv) 1995-12-08
EP0764049B1 (en) 2001-09-05

Similar Documents

Publication Publication Date Title
ES2164154T3 (es) Adsorbente de proteinas resistente a los alcalis.
ES2190447T3 (es) Pañal desechable.
DE68904802D1 (de) Schnellverbindungsvorrichtung fuer verbindungselemente von aufbauten, geruesten, traegern und anderen anordnungen.
DK0425066T3 (da) Krystallinsk 2-O-alpha-D-glucopyranosyl-L-ascorbinsyre og fremstilling heraf og anvendelser herfor
ES2170083T3 (es) Analizador con un dispositivo para la separacion de microparticulas magneticas.
FI932328A7 (fi) Analysaattoriviljelylaite, jossa on useita itsenäisesti käytettyjä kyvettejä kannattavia renkaita
DK1126859T3 (da) Blodleukocyt-aferese til behandling af HIV
NO885547L (no) Fremgangsmaate for aa fjerne polymergeler fra petroleum (olje og gass)-felter.
PT807178E (pt) Proteinas de micobacterias, microrganismos que as produzem e suas utilizacoes vacinicas e para a deteccao da tuberculose
DE69014593D1 (de) Gastrennung mit semipermeablen membranen.
ES2190808T3 (es) Uso de perlas en un lecho fluidizado.
NO884108L (no) Apparatur og fremgangsmaate for utslipp av gass i atmosfaeren.
ES2031237T3 (es) Metodo y aparato para ligar dinamicamente por medios mecanicos.
ATE244404T1 (de) Zusammensetzungen und verfahren zur hemmung der licht-induzierten inaktivierung von biologischen reagenzien
GB9603325D0 (en) A compound
DE69008041D1 (de) Membranen zur Gastrennung aus Copolyimid, abgeleitet von Methylendianilinen und unsubstituierten Diaminen.
AR071880A2 (es) Metodo para marcar de forma detectable pestivirus
DK211186D0 (da) Forbedring af moentholdere
BR8806088A (pt) Membrana de separacao de gas e processo para separar gases
EA200000196A1 (ru) Универсальная плазма крови
DK0476038T3 (da) Kemiske produkter
PT90012A (pt) Processo para a preparacao de tetra-hidrobenzo{c,d}indoles uteis como medicamentos
ES2187504T3 (es) Vectores no oncovirales, basados en el vmmp, con encapsidacion defectuosa.
NO307500B1 (no) Steril, bufret, i det vesentlige isotonisk saltvannsoppløsning
ES2119747T3 (es) Metodo para la preparacion y purificacion de una mezcla de glicosfingolipidos libre de contaminacion por virus no convencionales.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 764049

Country of ref document: ES