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ES2099727T3 - 8-azabiciclo(3.2.1)octilalquiltiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos. - Google Patents

8-azabiciclo(3.2.1)octilalquiltiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.

Info

Publication number
ES2099727T3
ES2099727T3 ES91117906T ES91117906T ES2099727T3 ES 2099727 T3 ES2099727 T3 ES 2099727T3 ES 91117906 T ES91117906 T ES 91117906T ES 91117906 T ES91117906 T ES 91117906T ES 2099727 T3 ES2099727 T3 ES 2099727T3
Authority
ES
Spain
Prior art keywords
octilalquiltiazolidinonas
azabiciclo
medicines
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91117906T
Other languages
English (en)
Inventor
Nicholas J Hrib
John G Jurcak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ES2099727T3 publication Critical patent/ES2099727T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVAS 8-AZABICICLO [ 3. 2. 1] OCTILALQUILTIAZOLIDINONAS DE FORMULA DONDE R ELEVADO 1 Y R (AL CUADRADO) SON INDEPENDIENTEMENTE HIDROGENO O ALQUILO; R ELEVADO 3 Y R ELEVADO 4 SON INDEPENDIENTEMENTE HIDROGENO O ALQUILO; X E Y SON INDEPENDIENTEMENTE HIDROGENO, ALQUILO, ALCOXI, HALOGENO O TRIFLUOROMETILO; N ES 2, 3, O 4, Y SON UTILES EN EL TRATAMIENTO DE PSICOSIS.
ES91117906T 1990-10-26 1991-10-21 8-azabiciclo(3.2.1)octilalquiltiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos. Expired - Lifetime ES2099727T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/603,491 US5045546A (en) 1990-10-26 1990-10-26 8-azabicyclo[3.2.1]octylalkylthiazolidines

Publications (1)

Publication Number Publication Date
ES2099727T3 true ES2099727T3 (es) 1997-06-01

Family

ID=24415671

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91117906T Expired - Lifetime ES2099727T3 (es) 1990-10-26 1991-10-21 8-azabiciclo(3.2.1)octilalquiltiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.

Country Status (19)

Country Link
US (1) US5045546A (es)
EP (1) EP0483633B1 (es)
JP (1) JP2564719B2 (es)
AT (1) ATE151422T1 (es)
AU (1) AU639195B2 (es)
BR (1) BR9104632A (es)
CA (1) CA2054225A1 (es)
CS (1) CS323091A3 (es)
DE (1) DE69125569T2 (es)
DK (1) DK0483633T3 (es)
ES (1) ES2099727T3 (es)
FI (1) FI915025A (es)
GR (1) GR3023441T3 (es)
HU (1) HUT59401A (es)
IE (1) IE913756A1 (es)
NO (1) NO914192L (es)
PT (1) PT99331B (es)
YU (1) YU168491A (es)
ZA (1) ZA918518B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK87287A (da) 1986-02-20 1987-08-21 Raychem Corp Fremgangsmaade og apparat for anvendelse af ionbyttemateriale
US5801186A (en) * 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
CA2157348A1 (en) * 1994-09-01 1996-03-02 Aventis Pharmaceuticals Inc. 3-¬4-(1-substituted-4-piperazinyl)butyl|-4-thiazolidinone and related compounds
CZ298824B6 (cs) 1997-05-30 2008-02-20 Neurosearch A/S Deriváty 8-azabicyklo[3.2.1]okt-2-enu, zpusob jejich prípravy a jejich použití
KR100812499B1 (ko) * 2006-10-16 2008-03-11 이도훈 항경련제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2804460A (en) * 1955-07-15 1957-08-27 Irwin Neisler And Company Tropene derivatives
US3452029A (en) * 1966-11-21 1969-06-24 American Home Prod 3-alpha-phenylbenzyloxy - 8 - substituted nortropanes and their substitutents
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
ATE81123T1 (de) * 1987-11-20 1992-10-15 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.

Also Published As

Publication number Publication date
PT99331B (pt) 2000-08-31
JP2564719B2 (ja) 1996-12-18
US5045546A (en) 1991-09-03
DE69125569D1 (de) 1997-05-15
EP0483633B1 (en) 1997-04-09
IE913756A1 (en) 1992-05-22
AU639195B2 (en) 1993-07-15
NO914192L (no) 1992-04-27
EP0483633A1 (en) 1992-05-06
FI915025A (fi) 1992-04-27
ATE151422T1 (de) 1997-04-15
DK0483633T3 (da) 1997-09-15
HU913370D0 (en) 1992-01-28
JPH04264085A (ja) 1992-09-18
HUT59401A (en) 1992-05-28
FI915025A0 (fi) 1991-10-24
NO914192D0 (no) 1991-10-25
AU8606291A (en) 1992-04-30
CA2054225A1 (en) 1992-04-27
GR3023441T3 (en) 1997-08-29
PT99331A (pt) 1992-09-30
DE69125569T2 (de) 1997-09-18
CS323091A3 (en) 1992-05-13
YU168491A (sh) 1995-01-31
ZA918518B (en) 1992-07-29
BR9104632A (pt) 1992-06-09

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