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ECSP10010002A - Derivados indólicos 2,3 sustituidos y métodos de uso de los mismos - Google Patents

Derivados indólicos 2,3 sustituidos y métodos de uso de los mismos

Info

Publication number
ECSP10010002A
ECSP10010002A EC2010010002A ECSP10010002A ECSP10010002A EC SP10010002 A ECSP10010002 A EC SP10010002A EC 2010010002 A EC2010010002 A EC 2010010002A EC SP10010002 A ECSP10010002 A EC SP10010002A EC SP10010002 A ECSP10010002 A EC SP10010002A
Authority
EC
Ecuador
Prior art keywords
methods
derivatives
indólicos
substitutes
same
Prior art date
Application number
EC2010010002A
Other languages
English (en)
Inventor
Joseph A Kozlowski
Neng Yang Shih
Frank Bennett
F George Njoroge
Kevin X Chen
Srikanth Venkatraman
Patrick A Pinto
Bancha Vibulbhan
Tin Yau Chan
Mousumi Sannigrahi
Qingbei Zeng
Stuart B Rosenblum
Yueheng Jiang
Charles A Lesburg
Jose S Duca
Francisco Velazquez
Gopinadhan N Anilkumar
Stephen J Gavalas
Haiyan Pu
Oleg B Selyutin
Li Wang
Wanli Wu
Weiying Yang
Yuhua Hunag
Hsueh-Cheng Huang
Robert Palermo
Boris Feld
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ECSP10010002A publication Critical patent/ECSP10010002A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a derivados indólicos 2,3 sustituidos, composiciones que comprenden por lo menos un derivado indólico 2,3 sustituido, y métodos de uso de los derivados indólicos 2,3 sustituidos para tratar o prevenir una infección viral o un trastorno relacionado con un virus en un paciente.
EC2010010002A 2007-08-29 2010-02-26 Derivados indólicos 2,3 sustituidos y métodos de uso de los mismos ECSP10010002A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96874507P 2007-08-29 2007-08-29

Publications (1)

Publication Number Publication Date
ECSP10010002A true ECSP10010002A (es) 2010-03-31

Family

ID=40220015

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010002A ECSP10010002A (es) 2007-08-29 2010-02-26 Derivados indólicos 2,3 sustituidos y métodos de uso de los mismos

Country Status (18)

Country Link
US (1) US8143305B2 (es)
EP (1) EP2197842B1 (es)
JP (1) JP5272007B2 (es)
KR (1) KR20100049667A (es)
CN (1) CN101842353A (es)
AR (1) AR068107A1 (es)
AU (1) AU2008295476B2 (es)
BR (1) BRPI0816116A2 (es)
CA (1) CA2697375A1 (es)
CL (1) CL2008002538A1 (es)
CO (1) CO6321236A2 (es)
EC (1) ECSP10010002A (es)
MX (1) MX2010002319A (es)
PE (1) PE20090995A1 (es)
RU (1) RU2010111550A (es)
TW (1) TW200924751A (es)
WO (1) WO2009032116A1 (es)
ZA (1) ZA201001335B (es)

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CA2673249C (en) * 2006-12-22 2013-04-30 Schering Corporation 4,5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections

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