EA201791300A1 - Флюидные системы, содержащие канал инкубации, включающие в себя флюидные системы, образованные литьевым формованием - Google Patents
Флюидные системы, содержащие канал инкубации, включающие в себя флюидные системы, образованные литьевым формованиемInfo
- Publication number
- EA201791300A1 EA201791300A1 EA201791300A EA201791300A EA201791300A1 EA 201791300 A1 EA201791300 A1 EA 201791300A1 EA 201791300 A EA201791300 A EA 201791300A EA 201791300 A EA201791300 A EA 201791300A EA 201791300 A1 EA201791300 A1 EA 201791300A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- incubation
- mixing
- fluid systems
- components
- channel
- Prior art date
Links
- 238000011534 incubation Methods 0.000 title abstract 10
- 239000012530 fluid Substances 0.000 title abstract 8
- 238000005266 casting Methods 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 4
- 238000004458 analytical method Methods 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Signal Processing (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Computer Vision & Pattern Recognition (AREA)
Abstract
Предусмотрены флюидные устройства и способы, включающие в себя инкубацию и/или смешивание компонентов анализа. В некоторых вариантах осуществления может быть выполнен биологический и/или химический анализ во флюидном устройстве. Флюидное устройство может быть выполнено с возможностью обеспечивать контролируемую инкубацию и/или смешение двух или более компонентов анализа. В некоторых таких вариантах осуществления флюидное устройство может содержать канал инкубации, имеющий относительно большой размер поперечного сечения, сообщающийся по текучей среде с каналом обнаружения. Канал инкубации может обеспечить адекватное смешивание и/или инкубацию двух или более компонентов анализа перед анализом данных анализа. В некоторых вариантах осуществления канал обнаружения используют для обеспечения обратной связи по степени инкубации и/или смешивания. На основании обратной связи один или несколько компонентов флюидной системы регулируют для обеспечения необходимой степени смешивания и/или инкубации. В некоторых вариантах осуществления контролируемая инкубация и/или смешение компонентов анализа в канале инкубации, как описано здесь, может обеспечить улучшенные характеристики анализа.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462091187P | 2014-12-12 | 2014-12-12 | |
US201562131357P | 2015-03-11 | 2015-03-11 | |
PCT/US2015/065187 WO2016094766A1 (en) | 2014-12-12 | 2015-12-11 | Fluidic systems comprising an incubation channel, including fluidic systems formed by molding |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201791300A1 true EA201791300A1 (ru) | 2017-11-30 |
EA038479B1 EA038479B1 (ru) | 2021-09-03 |
Family
ID=56108245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201791300A EA038479B1 (ru) | 2014-12-12 | 2015-12-11 | Устройство для проведения анализа пробы и способ эксплуатации указанного устройства |
Country Status (11)
Country | Link |
---|---|
US (2) | US10279345B2 (ru) |
EP (1) | EP3229963B1 (ru) |
JP (1) | JP6929773B2 (ru) |
KR (1) | KR102587637B1 (ru) |
CN (1) | CN107206376B (ru) |
AU (1) | AU2015360401B2 (ru) |
CA (1) | CA2970491A1 (ru) |
EA (1) | EA038479B1 (ru) |
MX (1) | MX2017007576A (ru) |
TW (1) | TWI728963B (ru) |
WO (1) | WO2016094766A1 (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102587637B1 (ko) | 2014-12-12 | 2023-10-10 | 옵코 다이어그노스틱스, 엘엘씨 | 성형에 의해 제조되는 유체 시스템을 비롯한, 항온 처리 채널을 포함하는 유체 시스템 |
US10852310B2 (en) | 2015-12-11 | 2020-12-01 | Opko Diagnostics, Llc | Fluidic systems involving incubation of samples and/or reagents |
CN108430639B (zh) * | 2015-12-29 | 2021-03-23 | 欧普科诊断有限责任公司 | 流体收集装置及相关方法 |
KR102547418B1 (ko) * | 2017-03-28 | 2023-06-23 | 덴카 주식회사 | 막 담체 및 이를 이용한 액체 시료 검사 키트 |
US20210031188A1 (en) | 2018-04-24 | 2021-02-04 | Hewlett-Packard Development Company, L.P. | Droplet ejectors to draw fluids through microfluidic networks |
US11925932B2 (en) | 2018-04-24 | 2024-03-12 | Hewlett-Packard Development Company, L.P. | Microfluidic devices |
US11547993B2 (en) | 2018-07-17 | 2023-01-10 | Hewlett-Packard Development Company, L.P. | Droplet ejectors with target media |
US11325380B2 (en) | 2018-07-17 | 2022-05-10 | Hewlett-Packard Development Company, L.P. | Droplet ejectors to provide fluids to droplet ejectors |
CN110306212B (zh) * | 2019-08-14 | 2021-07-30 | 济南东方结晶器有限公司 | 一种不含pfos的镀铬抑雾剂及其配制方法 |
CN110596107B (zh) * | 2019-09-23 | 2020-12-11 | 中国人民解放军陆军军医大学第一附属医院 | 一种可重复使用的高通量型太赫兹超材料快速检测方法 |
CN111545260B (zh) * | 2020-05-10 | 2022-05-24 | 天津德祥生物技术有限公司 | 处理微通道内表面的方法 |
CN114405568B (zh) * | 2022-03-04 | 2023-08-04 | 南开大学 | 一种自驱式微流控芯片 |
Family Cites Families (170)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3735640A (en) | 1972-03-10 | 1973-05-29 | L Chizhov | Apparatus for injecting a sample into a gas chromatograph |
US4318994A (en) | 1979-08-30 | 1982-03-09 | Mcdonnell Douglas Corporation | Enterobacteriaceae species biochemical test card |
US4387183A (en) | 1981-10-16 | 1983-06-07 | Atlantic Richfield Company | Thromboresistant molded article and method for its production |
US4517302A (en) | 1982-11-15 | 1985-05-14 | Technicon Instruments Corporation | Continuous flow metering apparatus |
CA1211157A (en) | 1982-11-22 | 1986-09-09 | Richard L. Columbus | Capillary transport device having means for increasing the viscosity of the transported liquid |
US4963498A (en) | 1985-08-05 | 1990-10-16 | Biotrack | Capillary flow device |
US4918025A (en) | 1987-03-03 | 1990-04-17 | Pb Diagnostic Systems, Inc. | Self contained immunoassay element |
US5051237A (en) | 1988-06-23 | 1991-09-24 | P B Diagnostic Systems, Inc. | Liquid transport system |
JPH02176466A (ja) | 1988-12-27 | 1990-07-09 | Mochida Pharmaceut Co Ltd | 液性試料中の特定物質の測定方法および測定器具 |
US5286454A (en) | 1989-04-26 | 1994-02-15 | Nilsson Sven Erik | Cuvette |
GB8915512D0 (en) | 1989-07-06 | 1989-08-23 | Sec Dep For Health | Silver enhanced gold-labelled immuno assay method |
AU642444B2 (en) | 1989-11-30 | 1993-10-21 | Mochida Pharmaceutical Co., Ltd. | Reaction vessel |
US6176962B1 (en) | 1990-02-28 | 2001-01-23 | Aclara Biosciences, Inc. | Methods for fabricating enclosed microchannel structures |
SE470347B (sv) | 1990-05-10 | 1994-01-31 | Pharmacia Lkb Biotech | Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system |
US5268147A (en) | 1992-02-26 | 1993-12-07 | Miles, Inc. | Reversible direction capsule chemistry sample liquid analysis system and method |
US5637469A (en) | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
US5726026A (en) | 1992-05-01 | 1998-03-10 | Trustees Of The University Of Pennsylvania | Mesoscale sample preparation device and systems for determination and processing of analytes |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
US5486335A (en) | 1992-05-01 | 1996-01-23 | Trustees Of The University Of Pennsylvania | Analysis based on flow restriction |
US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
CA2105515A1 (en) | 1993-09-03 | 1995-03-04 | Carlos A. Santizo Lescaille | Visual immunoassay method for the detection of ligands, based on the use of opaque plastic supports |
US6638482B1 (en) | 1993-11-01 | 2003-10-28 | Nanogen, Inc. | Reconfigurable detection and analysis apparatus and method |
US20040077074A1 (en) | 1993-11-01 | 2004-04-22 | Nanogen, Inc. | Multi-chambered analysis device |
US5478751A (en) | 1993-12-29 | 1995-12-26 | Abbott Laboratories | Self-venting immunodiagnositic devices and methods of performing assays |
CA2143365A1 (en) | 1994-03-14 | 1995-09-15 | Hugh V. Cottingham | Nucleic acid amplification method and apparatus |
US5580523A (en) | 1994-04-01 | 1996-12-03 | Bard; Allen J. | Integrated chemical synthesizers |
US5571410A (en) | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
US5603351A (en) | 1995-06-07 | 1997-02-18 | David Sarnoff Research Center, Inc. | Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device |
US5731212A (en) | 1994-12-20 | 1998-03-24 | International Technidyne Corporation | Test apparatus and method for testing cuvette accommodated samples |
GB9502112D0 (en) | 1995-02-03 | 1995-03-22 | British Biocell Int | Assay device and method |
US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
US6168948B1 (en) | 1995-06-29 | 2001-01-02 | Affymetrix, Inc. | Miniaturized genetic analysis systems and methods |
US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US6709869B2 (en) | 1995-12-18 | 2004-03-23 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
US6399023B1 (en) | 1996-04-16 | 2002-06-04 | Caliper Technologies Corp. | Analytical system and method |
US5885470A (en) | 1997-04-14 | 1999-03-23 | Caliper Technologies Corporation | Controlled fluid transport in microfabricated polymeric substrates |
US5942443A (en) | 1996-06-28 | 1999-08-24 | Caliper Technologies Corporation | High throughput screening assay systems in microscale fluidic devices |
CA2253710A1 (en) | 1996-04-25 | 1997-10-30 | Spectrametrix Inc. | Analyte assay using particulate labels |
US6586193B2 (en) | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
EP0907412B1 (en) | 1996-06-28 | 2008-08-27 | Caliper Life Sciences, Inc. | High-throughput screening assay systems in microscale fluidic devices |
CN1329729C (zh) | 1996-06-28 | 2007-08-01 | 卡钳生命科学股份有限公司 | 微流体系统 |
US6074827A (en) | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
AU5895898A (en) | 1996-12-20 | 1998-07-17 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
US6632619B1 (en) | 1997-05-16 | 2003-10-14 | The Governors Of The University Of Alberta | Microfluidic system and methods of use |
US6613512B1 (en) | 1997-06-09 | 2003-09-02 | Caliper Technologies Corp. | Apparatus and method for correcting for variable velocity in microfluidic systems |
US6375871B1 (en) | 1998-06-18 | 2002-04-23 | 3M Innovative Properties Company | Methods of manufacturing microfluidic articles |
US5876675A (en) | 1997-08-05 | 1999-03-02 | Caliper Technologies Corp. | Microfluidic devices and systems |
US20020092767A1 (en) | 1997-09-19 | 2002-07-18 | Aclara Biosciences, Inc. | Multiple array microfluidic device units |
US6136272A (en) | 1997-09-26 | 2000-10-24 | University Of Washington | Device for rapidly joining and splitting fluid layers |
US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
WO1999026071A1 (de) | 1997-11-19 | 1999-05-27 | Abion Beteiligungs- Und Verwaltungs-Gesellschaft Mbh | Mehrkanalsystem zur durchführung chemischer, biologischer und/oder biochemischer analyseverfahren |
US6251343B1 (en) | 1998-02-24 | 2001-06-26 | Caliper Technologies Corp. | Microfluidic devices and systems incorporating cover layers |
US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
JP3930970B2 (ja) | 1998-07-01 | 2007-06-13 | 日東電工株式会社 | 免疫学的検査方法および免疫学的検査用キット |
US6794197B1 (en) | 1998-07-14 | 2004-09-21 | Zyomyx, Inc. | Microdevice and method for detecting a characteristic of a fluid |
US6333200B1 (en) | 1998-07-27 | 2001-12-25 | University Of Delaware | Miniaturized immunosensor assembled from colloidal particles between micropatterned electrodes |
US6103199A (en) | 1998-09-15 | 2000-08-15 | Aclara Biosciences, Inc. | Capillary electroflow apparatus and method |
GB9822242D0 (en) | 1998-10-13 | 1998-12-09 | Zeneca Ltd | Device |
EP1125129A1 (en) | 1998-10-13 | 2001-08-22 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
US6146489A (en) | 1998-11-19 | 2000-11-14 | General Electric Company | Method and apparatus for depositing scintillator material on radiation imager |
US6416642B1 (en) | 1999-01-21 | 2002-07-09 | Caliper Technologies Corp. | Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection |
US20020019059A1 (en) | 1999-01-28 | 2002-02-14 | Calvin Y.H. Chow | Devices, systems and methods for time domain multiplexing of reagents |
EP1157270A1 (en) | 1999-02-03 | 2001-11-28 | Aclara BioSciences, Inc. | Multichannel control in microfluidics |
US6297020B1 (en) | 1999-03-01 | 2001-10-02 | Bayer Corporation | Device for carrying out lateral-flow assays involving more than one analyte |
JP2000323241A (ja) | 1999-05-12 | 2000-11-24 | Honda Tsushin Kogyo Co Ltd | コネクタ |
EP1054259A1 (en) | 1999-05-19 | 2000-11-22 | Remacle, José | Method for the identification of a target compound |
JP2001004628A (ja) | 1999-06-18 | 2001-01-12 | Kanagawa Acad Of Sci & Technol | 免疫分析装置と免疫分析方法 |
JP2001000197A (ja) | 1999-06-22 | 2001-01-09 | Fuji Photo Film Co Ltd | プロテアーゼ活性の測定方法 |
US7244402B2 (en) | 2001-04-06 | 2007-07-17 | California Institute Of Technology | Microfluidic protein crystallography |
JP2003505260A (ja) | 1999-07-23 | 2003-02-12 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシテイ オブ イリノイ | 微小成形加工された装置及びその製造方法 |
US6858185B1 (en) | 1999-08-25 | 2005-02-22 | Caliper Life Sciences, Inc. | Dilutions in high throughput systems with a single vacuum source |
WO2001014865A1 (en) | 1999-08-25 | 2001-03-01 | Caliper Technologies, Corp. | Dilutions in high throughput systems with a single vacuum source |
US20030040105A1 (en) | 1999-09-30 | 2003-02-27 | Sklar Larry A. | Microfluidic micromixer |
CN1117284C (zh) | 1999-10-27 | 2003-08-06 | 陆祖宏 | 微流体生物芯片检测分析板及其应用方法 |
US6361958B1 (en) | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
AU2610201A (en) | 2000-01-06 | 2001-07-16 | Caliper Technologies Corporation | Ultra high throughput sampling and analysis systems and methods |
EP1263533B1 (en) | 2000-03-14 | 2010-03-03 | Micronics, Inc. | Microfluidic analysis cartridge |
US20050118073A1 (en) | 2003-11-26 | 2005-06-02 | Fluidigm Corporation | Devices and methods for holding microfluidic devices |
WO2001079529A1 (en) | 2000-04-17 | 2001-10-25 | Purdue Research Foundation | Biosensor and related method |
AU6154101A (en) | 2000-05-11 | 2001-11-20 | Caliper Techn Corp | Microfluidic devices and methods to regulate hydrodynamic and electrical resistance utilizing bulk viscosity enhancers |
US20030118486A1 (en) | 2000-07-03 | 2003-06-26 | Xeotron Corporation | Fluidic methods and devices for parallel chemical reactions |
US20020142618A1 (en) | 2000-08-04 | 2002-10-03 | Caliper Technologies Corp. | Control of operation conditions within fluidic systems |
US6610499B1 (en) | 2000-08-31 | 2003-08-26 | The Regents Of The University Of California | Capillary array and related methods |
GB2366529A (en) | 2000-09-11 | 2002-03-13 | Univ Sheffield | Fluidic control valve for an assembly containing a plurality of microreactors |
CA2422110A1 (en) | 2000-09-18 | 2002-03-21 | President And Fellows Of Harvard College | Method and apparatus for gradient generation |
US6780584B1 (en) | 2000-09-27 | 2004-08-24 | Nanogen, Inc. | Electronic systems and component devices for macroscopic and microscopic molecular biological reactions, analyses and diagnostics |
US6934836B2 (en) | 2000-10-06 | 2005-08-23 | Protasis Corporation | Fluid separation conduit cartridge with encryption capability |
US6827095B2 (en) | 2000-10-12 | 2004-12-07 | Nanostream, Inc. | Modular microfluidic systems |
JP2002236131A (ja) | 2000-12-08 | 2002-08-23 | Minolta Co Ltd | マイクロチップ |
US6878755B2 (en) | 2001-01-22 | 2005-04-12 | Microgen Systems, Inc. | Automated microfabrication-based biodetector |
US6524656B2 (en) | 2001-02-23 | 2003-02-25 | Rohm And Haas Company | Coating method |
US6949377B2 (en) | 2001-03-05 | 2005-09-27 | Ho Winston Z | Chemiluminescence-based microfluidic biochip |
DE10111457B4 (de) | 2001-03-09 | 2006-12-14 | Siemens Ag | Diagnoseeinrichtung |
DE10115474A1 (de) | 2001-03-29 | 2002-10-10 | Infineon Technologies Ag | Mikrofluidkanalstruktur und Verfahren zur Herstellung einer derartigen Mikrofluidkanalstruktur |
US6742661B1 (en) | 2001-04-03 | 2004-06-01 | Micronics, Inc. | Well-plate microfluidics |
JP4627607B2 (ja) | 2001-05-14 | 2011-02-09 | 三菱化学メディエンス株式会社 | 複数項目及び総含有量の同時分析可能なイムノクロマトグラフ法及びイムノクロマトグラフ用ストリップ |
EP1262545A1 (de) | 2001-05-31 | 2002-12-04 | Direvo Biotech AG | Mikrostrukturen und deren Verwendung für die gerichtete Evolution von Biomolekülen |
KR100425536B1 (ko) | 2001-07-16 | 2004-03-30 | 학교법인 포항공과대학교 | 유체 마이크로칩용 브레드보드 |
JP2003075444A (ja) | 2001-08-31 | 2003-03-12 | Mitsubishi Chemicals Corp | 測定対象物の測定用チップ,測定対象物の測定装置及び測定対象物の測定方法 |
JP2005528582A (ja) | 2001-09-07 | 2005-09-22 | コーニング インコーポレイテッド | ハイスループット分析のためのマイクロカラム・プラットフォームに基づくアレイ |
US7094379B2 (en) | 2001-10-24 | 2006-08-22 | Commissariat A L'energie Atomique | Device for parallel and synchronous injection for sequential injection of different reagents |
US20030138969A1 (en) | 2002-01-24 | 2003-07-24 | Jakobsen Mogens Havsteen | Closed substrate platforms suitable for analysis of biomolecules |
EP1446274A4 (en) | 2001-10-26 | 2010-06-30 | Aclara Biosciences Inc | SYSTEM AND METHOD FOR SPLASHED MICROREPLICATION OF MICROFLUIDATE SUBSTRATES |
AU2002360499A1 (en) | 2001-12-05 | 2003-06-17 | University Of Washington | Microfluidic device and surface decoration process for solid phase affinity binding assays |
WO2003054513A2 (en) | 2001-12-20 | 2003-07-03 | Radius Biosciences | Centrifugal array processing device |
US6982787B1 (en) | 2002-01-02 | 2006-01-03 | The United States Of America As Represented By The Secretary Of The Air Force | Modification of the degree of liquid contact with a solid by control of surface and micro-channel capillary geometry |
GB0201498D0 (en) | 2002-01-23 | 2002-03-13 | Biotech Res Ventures Pte Ltd | Materials and methods for treating cancer |
JP4475858B2 (ja) | 2002-01-30 | 2010-06-09 | 富士電機リテイルシステムズ株式会社 | 自動販売機 |
EP2581739B1 (en) | 2002-03-05 | 2015-11-04 | Caliper Life Sciences, Inc. | Microfluidic separation method with combined pressure and voltage control |
US7524462B2 (en) | 2002-03-29 | 2009-04-28 | Agilent Technologies, Inc. | Capillary flow for a heterogenous assay in a micro-channel environment |
EP2283918B1 (en) | 2002-05-09 | 2022-10-05 | The University of Chicago | Device and method for pressure-driven plug transport and reaction |
US7244961B2 (en) | 2002-08-02 | 2007-07-17 | Silicon Valley Scientific | Integrated system with modular microfluidic components |
US7605002B2 (en) | 2002-09-06 | 2009-10-20 | Epigem Limited | Modular microfluidic system |
US6878271B2 (en) | 2002-09-09 | 2005-04-12 | Cytonome, Inc. | Implementation of microfluidic components in a microfluidic system |
US6806543B2 (en) * | 2002-09-12 | 2004-10-19 | Intel Corporation | Microfluidic apparatus with integrated porous-substrate/sensor for real-time (bio)chemical molecule detection |
DE10251721B4 (de) | 2002-11-06 | 2006-06-01 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Beschickung von Probenkammern mit Suspensionsproben |
US20050221281A1 (en) | 2003-01-08 | 2005-10-06 | Ho Winston Z | Self-contained microfluidic biochip and apparatus |
US20040185445A1 (en) | 2003-03-19 | 2004-09-23 | Ye Fang | Universal readout for target identification using biological microarrays |
WO2004087283A1 (en) | 2003-03-25 | 2004-10-14 | Massachusetts Institute Of Technology | Fluid separation |
DE10315074A1 (de) | 2003-04-02 | 2004-10-14 | Clondiag Chip Technologies Gmbh | Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren |
US7300802B2 (en) | 2003-04-25 | 2007-11-27 | Biodigit Laboratories Corp. | Membrane strip biosensor system for point-of-care testing |
US7011793B2 (en) | 2003-05-15 | 2006-03-14 | Kionix, Inc. | Reconfigurable modular microfluidic system and method of fabrication |
US7247487B2 (en) | 2003-06-18 | 2007-07-24 | Ortho-Clinical Diagnostics | Reducing working fluid dilution in liquid systems |
AU2003292497A1 (en) | 2003-12-10 | 2005-06-29 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | A modular biochip assembly |
AU2004312893B2 (en) | 2003-12-31 | 2010-06-17 | President And Fellows Of Harvard College | Assay device and method |
US8030057B2 (en) | 2004-01-26 | 2011-10-04 | President And Fellows Of Harvard College | Fluid delivery system and method |
EP1776181B1 (en) | 2004-01-26 | 2013-09-11 | The President and Fellows of Harvard College | Fluid delivery system and method |
US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
US20060257991A1 (en) * | 2004-02-27 | 2006-11-16 | Mcdevitt John T | Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements |
US7655470B2 (en) | 2004-10-29 | 2010-02-02 | University Of Chicago | Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems |
EP1611954A1 (en) | 2004-07-03 | 2006-01-04 | Roche Diagnostics GmbH | Liquid reservoir connector |
WO2006018044A1 (en) | 2004-08-18 | 2006-02-23 | Agilent Technologies, Inc. | Microfluidic assembly with coupled microfluidic devices |
US7622509B2 (en) | 2004-10-01 | 2009-11-24 | Velocys, Inc. | Multiphase mixing process using microchannel process technology |
EP1805501A2 (en) | 2004-10-12 | 2007-07-11 | Fastraq, Inc. | Apparatus and method for a precision flow assay |
GB0426082D0 (en) | 2004-11-26 | 2004-12-29 | Norchip As | A device for carrying out biological assays |
WO2006113727A2 (en) | 2005-04-19 | 2006-10-26 | President And Fellows Of Harvard College | Fluidic structures including meandering and wide channels |
US20060254916A1 (en) | 2005-05-16 | 2006-11-16 | Hernandez Juan J | Methods of forming microfluidic devices and uses thereof |
US20060275852A1 (en) | 2005-06-06 | 2006-12-07 | Montagu Jean I | Assays based on liquid flow over arrays |
US20090282978A1 (en) | 2005-07-05 | 2009-11-19 | Massachusetts Institute Of Technology | Microfluidic Separators for Multiphase Fluid-Flow Based On Membranes |
WO2007024798A2 (en) | 2005-08-22 | 2007-03-01 | Applera Corporation | Apparatus, system, and method using immiscible-fluid-discrete-volumes |
US20070048189A1 (en) | 2005-08-26 | 2007-03-01 | Applera Corporation | Fluid processing device, system, kit, and method |
US7540475B2 (en) | 2005-09-16 | 2009-06-02 | Battelle Memorial Institute | Mixing in wicking structures and the use of enhanced mixing within wicks in microchannel devices |
DE102005048236A1 (de) | 2005-10-07 | 2007-04-12 | Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg | Vorrichtung und Verfahren zur Bestimmung der Volumenanteile der Phasen in einer Suspension |
JP4888394B2 (ja) | 2005-11-07 | 2012-02-29 | コニカミノルタエムジー株式会社 | マイクロリアクタおよびそれを用いた送液方法 |
DE102005055866A1 (de) | 2005-11-23 | 2007-05-24 | Hte Ag The High Throughput Experimentation Company | Verfahren zur Herstellung von Aryl-Aryl gekoppelter Verbindungen |
CA2640024A1 (en) | 2006-01-27 | 2007-08-09 | President And Fellows Of Harvard College | Fluidic droplet coalescence |
US20080085219A1 (en) | 2006-10-05 | 2008-04-10 | Beebe David J | Microfluidic platform and method |
JP4920553B2 (ja) | 2006-11-08 | 2012-04-18 | 富士フイルム株式会社 | イムノクロマトグラフキット |
JP2008263959A (ja) | 2007-03-23 | 2008-11-06 | Toshiba Corp | 核酸検出カセット及び核酸検出装置 |
WO2008118098A1 (en) | 2007-03-26 | 2008-10-02 | Agency For Science, Technology And Research | Fluid cartridge, pump and fluid valve arrangement |
EP2152417B1 (en) * | 2007-05-04 | 2018-07-11 | Opko Diagnostics, LLC | Device and method for analyses in microfluidic systems |
EP1992404B1 (en) | 2007-05-15 | 2011-03-23 | Corning Incorporated | Microfluidic device and method for immiscible liquid - liquid reactions |
US9795697B2 (en) | 2007-09-19 | 2017-10-24 | Opko Diagnostics, Llc | Liquid containment for integrated assays |
US9138700B2 (en) | 2008-01-18 | 2015-09-22 | The Regents Of The University Of California | Accurate and rapid micromixer for integrated microfluidic devices |
WO2009131677A1 (en) | 2008-04-25 | 2009-10-29 | Claros Diagnostics, Inc. | Flow control in microfluidic systems |
US7999937B1 (en) * | 2008-05-13 | 2011-08-16 | Sandia Corporation | Microfluidic devices and methods for integrated flow cytometry |
EP2304445B1 (en) * | 2008-07-09 | 2020-06-10 | Micropoint Bioscience Inc | Analytical cartridge with fluid flow control |
WO2010056331A2 (en) | 2008-11-14 | 2010-05-20 | Massachusetts Institute Of Technology | Small-scale method and appratus for separating mixtures |
US8591829B2 (en) | 2008-12-18 | 2013-11-26 | Opko Diagnostics, Llc | Reagent storage in microfluidic systems and related articles and methods |
EP2391451B1 (en) | 2009-02-02 | 2018-09-12 | Opko Diagnostics, LLC | Structures for controlling light interaction with microfluidic devices |
JP5116112B2 (ja) | 2009-02-19 | 2013-01-09 | シャープ株式会社 | 流体混合装置及び流体混合方法 |
US20120003122A1 (en) * | 2009-03-20 | 2012-01-05 | Avantium Holding B.V. | Flow controller assembly for microfluidic applications and system for performing a plurality of experiments in parallel |
US8481303B2 (en) | 2009-10-12 | 2013-07-09 | Corning Incorporated | Microfluidic device for cell culture |
CN102740975B (zh) | 2009-11-24 | 2015-11-25 | 欧普科诊断有限责任公司 | 微流体系统中的流体混合和递送 |
EA022356B1 (ru) | 2010-04-16 | 2015-12-30 | Опкоу Дайагностикс, Ллк | Способ управления средами в микрофлюидных системах с обратной связью |
US10145842B2 (en) * | 2012-04-11 | 2018-12-04 | Quidel Cardiovascular Inc. | Microfluidic device, system and method |
WO2014158367A1 (en) | 2013-03-13 | 2014-10-02 | Opko Diagnostics, Llc | Mixing of fluids in fluidic systems |
CN103464230B (zh) * | 2013-09-25 | 2015-02-18 | 中国科学院长春光学精密机械与物理研究所 | 离心式全血分析微流控芯片、制备方法及其应用方法 |
KR102587637B1 (ko) | 2014-12-12 | 2023-10-10 | 옵코 다이어그노스틱스, 엘엘씨 | 성형에 의해 제조되는 유체 시스템을 비롯한, 항온 처리 채널을 포함하는 유체 시스템 |
US10852310B2 (en) * | 2015-12-11 | 2020-12-01 | Opko Diagnostics, Llc | Fluidic systems involving incubation of samples and/or reagents |
-
2015
- 2015-12-11 KR KR1020177019032A patent/KR102587637B1/ko active IP Right Grant
- 2015-12-11 WO PCT/US2015/065187 patent/WO2016094766A1/en active Application Filing
- 2015-12-11 CN CN201580075071.0A patent/CN107206376B/zh active Active
- 2015-12-11 US US14/966,937 patent/US10279345B2/en active Active
- 2015-12-11 EA EA201791300A patent/EA038479B1/ru unknown
- 2015-12-11 CA CA2970491A patent/CA2970491A1/en active Pending
- 2015-12-11 EP EP15867125.5A patent/EP3229963B1/en active Active
- 2015-12-11 TW TW104141843A patent/TWI728963B/zh active
- 2015-12-11 MX MX2017007576A patent/MX2017007576A/es unknown
- 2015-12-11 JP JP2017531235A patent/JP6929773B2/ja active Active
- 2015-12-11 AU AU2015360401A patent/AU2015360401B2/en active Active
-
2019
- 2019-03-18 US US16/355,927 patent/US11253853B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2015360401A1 (en) | 2017-06-29 |
JP6929773B2 (ja) | 2021-09-01 |
CN107206376B (zh) | 2021-07-09 |
CN107206376A (zh) | 2017-09-26 |
JP2017538416A (ja) | 2017-12-28 |
EP3229963B1 (en) | 2023-08-23 |
KR102587637B1 (ko) | 2023-10-10 |
EP3229963A4 (en) | 2018-12-26 |
US20190336968A1 (en) | 2019-11-07 |
US20160207042A1 (en) | 2016-07-21 |
MX2017007576A (es) | 2018-03-09 |
KR20170118042A (ko) | 2017-10-24 |
TW201642952A (zh) | 2016-12-16 |
AU2015360401B2 (en) | 2021-05-06 |
CA2970491A1 (en) | 2016-06-16 |
US11253853B2 (en) | 2022-02-22 |
EA038479B1 (ru) | 2021-09-03 |
EP3229963A1 (en) | 2017-10-18 |
US10279345B2 (en) | 2019-05-07 |
TWI728963B (zh) | 2021-06-01 |
WO2016094766A1 (en) | 2016-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA201791300A1 (ru) | Флюидные системы, содержащие канал инкубации, включающие в себя флюидные системы, образованные литьевым формованием | |
MX2016013156A (es) | Dispositivos, sistemas y metodos fluidicos, para encapsular y dividir reactivos, y aplicaciones de los mismos. | |
MX2021008470A (es) | Sistemas y metodos para multiples analisis. | |
EA201991662A1 (ru) | Новые системы и способы ферментации | |
MX2018015704A (es) | Control de fluidos. | |
MX2021001694A (es) | Sistemas y metodos para proporcionar recomendaciones de bienestar, nutricion y/o salud animal. | |
GB2569252A (en) | Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing | |
BR112015001592A8 (pt) | análise de imagem e medidas de amostras biológicas | |
WO2015063552A3 (en) | Microfluidic system and method with focused energy apparatus | |
MX362545B (es) | Analisis de imagen y medicion de muestras biologicas. | |
BR112019000284A2 (pt) | aparelho de coleta de fluido | |
EP3471883A4 (en) | PIPETTING DEVICE, PIPETTE TIP COUPLER AND PIPETTLE TIP: DEVICES AND METHOD | |
CL2016001867A1 (es) | Sistema y dispositivo para la generación de alto rendimiento de gotitas y métodos de uso combinatorios. | |
WO2014124336A3 (en) | Partitioning and processing of analytes and other species | |
EP4219745A3 (en) | Spatially encoded biological assays using a microfluidic device | |
EP3561516A4 (en) | REACTION INCUBATION DEVICE, IMMUNITY ANALYZER AND REACTION INCUBATION PROCESS | |
AR087419A1 (es) | Metodos para el monitoreo y la modificacion de una corriente de fluido usando dispositivo opticoanaliticos | |
CA2900708C (en) | Mixing of fluids in fluidic systems | |
Salvati | MIX is a 2-MCFL and the word problem in Z2 is captured by the IO and the OI hierarchies | |
MX2017005888A (es) | Dispositivos, sistemas y metodos para la deteccion de analitos. | |
GB2545850A (en) | System and method using a combined modality optical probe | |
GB2531213A (en) | Systems and methods for high throughput analysis of conformation in biological entities | |
GB2582190A8 (en) | Methods and systems for determining an internal property of a food product | |
BR112019006862A2 (pt) | dispositivo de análise e método para testagem de uma amostra | |
EA201792456A1 (ru) | Ферментёр для получения псевдопластической среды |