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EA201100867A1 - Противоопухолевые комбинации, содержащие антитела, специфично распознающие cd38, и винкристин - Google Patents

Противоопухолевые комбинации, содержащие антитела, специфично распознающие cd38, и винкристин

Info

Publication number
EA201100867A1
EA201100867A1 EA201100867A EA201100867A EA201100867A1 EA 201100867 A1 EA201100867 A1 EA 201100867A1 EA 201100867 A EA201100867 A EA 201100867A EA 201100867 A EA201100867 A EA 201100867A EA 201100867 A1 EA201100867 A1 EA 201100867A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vinkristins
tumoral
combinations
specifically recognizing
containing antibodies
Prior art date
Application number
EA201100867A
Other languages
English (en)
Other versions
EA026092B1 (ru
Inventor
Паскаль Лежен
Патрисья Вриньо
Original Assignee
Санофи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофи filed Critical Санофи
Publication of EA201100867A1 publication Critical patent/EA201100867A1/ru
Publication of EA026092B1 publication Critical patent/EA026092B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Фармацевтическая композиция, включающая антитело, специфично распознающее CD38, и винкристин.
EA201100867A 2008-11-28 2009-11-27 Фармацевтическая комбинация, содержащая антитело, специфично распознающее cd38, и винкристин, и способ лечения рака EA026092B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08291117A EP2191841A1 (en) 2008-11-28 2008-11-28 Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine
PCT/IB2009/055390 WO2010061358A1 (en) 2008-11-28 2009-11-27 Antitumor combinations containing antibodies recognizing specifically cd38 and vincristine

Publications (2)

Publication Number Publication Date
EA201100867A1 true EA201100867A1 (ru) 2011-10-31
EA026092B1 EA026092B1 (ru) 2017-03-31

Family

ID=40627439

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100867A EA026092B1 (ru) 2008-11-28 2009-11-27 Фармацевтическая комбинация, содержащая антитело, специфично распознающее cd38, и винкристин, и способ лечения рака

Country Status (31)

Country Link
US (1) US8633301B2 (ru)
EP (2) EP2191841A1 (ru)
JP (2) JP2012510462A (ru)
KR (1) KR101733253B1 (ru)
CN (1) CN102264388B (ru)
AR (1) AR074220A1 (ru)
AU (1) AU2009321250B2 (ru)
BR (1) BRPI0922304B1 (ru)
CA (1) CA2744996C (ru)
CL (1) CL2011001255A1 (ru)
CO (1) CO6361946A2 (ru)
CR (1) CR20110281A (ru)
DO (1) DOP2011000118A (ru)
EA (1) EA026092B1 (ru)
EC (1) ECSP11011064A (ru)
HK (1) HK1164153A1 (ru)
HN (1) HN2011001420A (ru)
IL (1) IL213117A (ru)
MA (1) MA32895B1 (ru)
MX (1) MX2011005539A (ru)
NI (1) NI201100106A (ru)
NZ (1) NZ592992A (ru)
PA (1) PA8850001A1 (ru)
PE (1) PE20110821A1 (ru)
SG (1) SG171822A1 (ru)
TN (1) TN2011000163A1 (ru)
TW (1) TWI457124B (ru)
UA (1) UA105507C2 (ru)
UY (1) UY32265A (ru)
WO (1) WO2010061358A1 (ru)
ZA (1) ZA201103923B (ru)

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EP2191840A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
LT2621531T (lt) 2010-09-27 2017-04-10 Morphosys Ag Anti-cd38 antikūnas ir lenalidomidas arba bortezomibas, skirti išsėtinės mielomos ir nhl (nehodžino limfoma) gydymui
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
CA2885792C (en) 2012-09-25 2021-09-28 Jan Endell Pharmaceutical combination of an anti-cd38 antibody and melphalan for treating multiple myeloma
CA2927099A1 (en) * 2013-10-31 2015-05-07 Sanofi Specific anti-cd38 antibodies for treating human cancers
US9603927B2 (en) 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
WO2015200626A1 (en) * 2014-06-25 2015-12-30 The Rockefeller University Compositions and methods for rapid production of versatile nanobody repertoires
WO2016022589A2 (en) 2014-08-08 2016-02-11 The Regents Of The University Of California Methods for treating multiple myeloma
US20160067205A1 (en) 2014-09-09 2016-03-10 Janssen Biotech, Inc. Combination Therapies with Anti-CD38 Antibodies
WO2016089960A1 (en) 2014-12-04 2016-06-09 Janssen Biotech, Inc. Anti-cd38 antibodies for treatment of acute myeloid leukemia
AU2016264725B2 (en) 2015-05-20 2021-05-27 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of light chain amyloidosis and other CD38-positive hematological malignancies
US20180161302A1 (en) * 2015-06-11 2018-06-14 Bionomics Limited Pharmaceutical combination and uses thereof
KR102601550B1 (ko) 2015-06-22 2023-11-10 얀센 바이오테크 인코포레이티드 항-cd38 항체 및 서바이빈 억제제를 사용한 헴 악성종양에 대한 병용 요법
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
WO2017079150A1 (en) 2015-11-03 2017-05-11 Janssen Biotech, Inc. Subcutaneous formulations of anti-cd38 antibodies and their uses
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
AU2018359527A1 (en) 2017-10-31 2020-05-07 Janssen Biotech, Inc. Methods of treating high risk multiple myeloma
WO2020187718A1 (en) 2019-03-15 2020-09-24 Morphosys Ag Anti-cd38 antibodies and pharmaceutical compositions thereof for the treatment of autoantibody-mediated autoimmune disease
US11655302B2 (en) 2019-06-10 2023-05-23 Sanofi Anti-CD38 antibodies and formulations
CN112876563B (zh) 2019-11-29 2022-08-16 康诺亚生物医药科技（成都）有限公司 药物组合物及其制备方法和应用
TW202133879A (zh) 2019-12-05 2021-09-16 美商賽諾菲阿凡提斯美國有限責任公司 用於皮下投予之抗cd38抗體的調配物
KR20230142834A (ko) 2021-01-14 2023-10-11 모르포시스 아게 항-cd38 항체 및 이의 용도
TW202302642A (zh) 2021-03-01 2023-01-16 德商莫菲西斯公司 用於治療抗體介導移植物排斥用途之抗ｃｄ３８抗體
TW202321303A (zh) 2021-07-19 2023-06-01 德商莫菲西斯公司 抗pla2r自體抗體媒介膜性腎病變之治療

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Also Published As

Publication number Publication date
IL213117A (en) 2017-08-31
CR20110281A (es) 2011-12-07
EP2370095A1 (en) 2011-10-05
PE20110821A1 (es) 2011-11-19
TW201024310A (en) 2010-07-01
EP2191841A1 (en) 2010-06-02
IL213117A0 (en) 2011-07-31
PA8850001A1 (es) 2010-07-27
AU2009321250A1 (en) 2010-06-03
JP2015172049A (ja) 2015-10-01
KR20110091785A (ko) 2011-08-12
US20110293606A1 (en) 2011-12-01
ZA201103923B (en) 2012-09-26
TWI457124B (zh) 2014-10-21
CL2011001255A1 (es) 2012-01-27
DOP2011000118A (es) 2011-06-30
EP2370095B1 (en) 2020-04-01
JP2012510462A (ja) 2012-05-10
NZ592992A (en) 2012-12-21
BRPI0922304B1 (pt) 2022-08-09
CO6361946A2 (es) 2012-01-20
ECSP11011064A (es) 2011-07-29
UY32265A (es) 2010-06-30
HK1164153A1 (en) 2012-09-21
JP6130871B2 (ja) 2017-05-17
MA32895B1 (fr) 2011-12-01
KR101733253B1 (ko) 2017-05-08
TN2011000163A1 (en) 2012-12-17
WO2010061358A1 (en) 2010-06-03
EA026092B1 (ru) 2017-03-31
CN102264388B (zh) 2014-07-16
CA2744996A1 (en) 2010-06-03
AR074220A1 (es) 2010-12-29
AU2009321250B2 (en) 2016-05-26
HN2011001420A (es) 2014-01-13
NI201100106A (es) 2011-09-26
CN102264388A (zh) 2011-11-30
MX2011005539A (es) 2011-10-10
CA2744996C (en) 2019-05-07
US8633301B2 (en) 2014-01-21
BRPI0922304A2 (pt) 2016-06-21
UA105507C2 (ru) 2014-05-26
SG171822A1 (en) 2011-07-28

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