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EA200802365A1 - Аминометилзамещенные тетрациклиновые соединения - Google Patents

Аминометилзамещенные тетрациклиновые соединения

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Publication number
EA200802365A1
EA200802365A1 EA200802365A EA200802365A EA200802365A1 EA 200802365 A1 EA200802365 A1 EA 200802365A1 EA 200802365 A EA200802365 A EA 200802365A EA 200802365 A EA200802365 A EA 200802365A EA 200802365 A1 EA200802365 A1 EA 200802365A1
Authority
EA
Eurasian Patent Office
Prior art keywords
aminomethylene
testing
aminomethyl
considered
methods
Prior art date
Application number
EA200802365A
Other languages
English (en)
Inventor
Марк Л. Нельсон
Квази Охеменг
Роджер Фречетт
Мохамед И. Исмаил
Лора Макинтайр
Тодд Баузер
Пол Абато
Виктор Эму
Харегевейн Эссефа
Джоел Берняк
Бина Бхатиа
Джексон Чен
Оак Ким
Рашид Мечиче
Н. Лаксма Редди
Этул К. Верма
Питер Виски
Тадеуш Уорчол
Иван Яначков
Original Assignee
Паратек Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Паратек Фармасьютикалс, Инк. filed Critical Паратек Фармасьютикалс, Инк.
Publication of EA200802365A1 publication Critical patent/EA200802365A1/ru

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

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Abstract

Рассмотрены аминометилзамещенные тетрациклиновые соединения, фармацевтические композиции и способы их применения.
EA200802365A 2002-03-08 2003-03-10 Аминометилзамещенные тетрациклиновые соединения EA200802365A1 (ru)

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EA200401169A EA013819B1 (ru) 2002-03-08 2003-03-10 Аминометилзамещенные тетрациклиновые соединения
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JP2010195796A (ja) 2010-09-09
JP2008266330A (ja) 2008-11-06
WO2003075857A2 (en) 2003-09-18
EP2311451A1 (en) 2011-04-20
AU2009208042A1 (en) 2009-08-27
AU2003220123A1 (en) 2003-09-22
JP2011102296A (ja) 2011-05-26
AU2009208042B2 (en) 2013-02-14
EA200401169A1 (ru) 2005-04-28
AU2003220123B2 (en) 2009-05-07
KR20110038186A (ko) 2011-04-13
KR101093842B1 (ko) 2011-12-13
CN1649582A (zh) 2005-08-03
US20050026875A1 (en) 2005-02-03
CA2478335A1 (en) 2003-09-18
US7326696B2 (en) 2008-02-05
KR20100090310A (ko) 2010-08-13
CN102531948A (zh) 2012-07-04
EP1482926A2 (en) 2004-12-08
WO2003075857A3 (en) 2004-02-05
IL163931A (en) 2013-06-27
CA2478335C (en) 2011-05-10
EP2316450A1 (en) 2011-05-04
IL163931A0 (en) 2005-12-18
JP2005526754A (ja) 2005-09-08
KR101014918B1 (ko) 2011-02-15
KR101163937B1 (ko) 2012-07-09
EP2301534A1 (en) 2011-03-30
EA201000491A1 (ru) 2010-08-30
CN101307017A (zh) 2008-11-19
EA013819B1 (ru) 2010-08-30
US20080015169A1 (en) 2008-01-17
KR20040097160A (ko) 2004-11-17
IL213220A0 (en) 2011-07-31

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