Nothing Special   »   [go: up one dir, main page]

DK447387A - Hexahydroarylquinolizinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents

Hexahydroarylquinolizinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse

Info

Publication number
DK447387A
DK447387A DK447387A DK447387A DK447387A DK 447387 A DK447387 A DK 447387A DK 447387 A DK447387 A DK 447387A DK 447387 A DK447387 A DK 447387A DK 447387 A DK447387 A DK 447387A
Authority
DK
Denmark
Prior art keywords
hexahydroarylquinolizin
compound
connection
pharmaceutical preparation
preparation containing
Prior art date
Application number
DK447387A
Other languages
English (en)
Other versions
DK447387D0 (da
Inventor
John J Baldwin
Joel R Huff
Solms S Jane De
Joseph P Vacca
J Mark Wiggins
Steven D Young
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK447387D0 publication Critical patent/DK447387D0/da
Publication of DK447387A publication Critical patent/DK447387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK447387A 1986-08-28 1987-08-27 Hexahydroarylquinolizinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse DK447387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90148586A 1986-08-28 1986-08-28

Publications (2)

Publication Number Publication Date
DK447387D0 DK447387D0 (da) 1987-08-27
DK447387A true DK447387A (da) 1988-02-29

Family

ID=25414273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK447387A DK447387A (da) 1986-08-28 1987-08-27 Hexahydroarylquinolizinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse

Country Status (14)

Country Link
EP (1) EP0259092B1 (da)
JP (1) JP2582799B2 (da)
KR (1) KR880002869A (da)
AT (1) ATE78482T1 (da)
AU (1) AU597412B2 (da)
CA (1) CA1288435C (da)
DE (1) DE3780542T2 (da)
DK (1) DK447387A (da)
ES (1) ES2044944T3 (da)
GR (1) GR3005537T3 (da)
IL (1) IL83586A (da)
NZ (1) NZ221485A (da)
PT (1) PT85593B (da)
ZA (1) ZA876400B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942235A (en) * 1989-03-16 1990-07-17 Merck & Co., Inc. Process for certain (2R-trans)hexahydroaroquinolizines
US5229387A (en) * 1991-09-20 1993-07-20 Syntex (U.S.A.) Inc. Decahydro-8H-isoquino[2,1-g][1,6]naphthyridine and decahydrobenzo[a]pyrrolo [2,3-e]quinolizine derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6141745A (en) * 1998-04-30 2000-10-31 Advanced Micro Devices, Inc. Functional bit identifying a prefix byte via a particular state regardless of type of instruction
FI126838B (en) 2014-12-16 2017-06-15 Vetcare Oy Process for the preparation of spirocyclic substituted benzofuroquinolizines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1435573A (en) * 1973-05-25 1976-05-12 Wyeth John & Brother Ltd Indoloquinolizines
GB2106909B (en) * 1981-10-07 1984-09-19 Wyeth John & Brother Ltd Benzoquinolizines
IE57014B1 (en) * 1983-03-25 1992-03-11 Wyeth John & Brother Ltd Benzoquinolizines
PT79871B (en) * 1984-02-02 1986-12-15 Merck & Co Inc Process for preparing substituted hexahydro arylquinolizines
NZ216283A (en) * 1985-06-03 1989-10-27 Merck & Co Inc Hexahydro arylquinolizine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ZA876400B (en) 1988-02-25
AU7720587A (en) 1988-03-03
IL83586A0 (en) 1988-01-31
DE3780542D1 (en) 1992-08-27
CA1288435C (en) 1991-09-03
JPS63139183A (ja) 1988-06-10
JP2582799B2 (ja) 1997-02-19
ES2044944T3 (es) 1994-01-16
KR880002869A (ko) 1988-05-12
ATE78482T1 (de) 1992-08-15
NZ221485A (en) 1991-04-26
EP0259092A1 (en) 1988-03-09
DE3780542T2 (de) 1993-01-07
EP0259092B1 (en) 1992-07-22
GR3005537T3 (da) 1993-06-07
PT85593A (en) 1987-09-01
AU597412B2 (en) 1990-05-31
PT85593B (pt) 1990-05-31
IL83586A (en) 1991-12-15
DK447387D0 (da) 1987-08-27

Similar Documents

Publication Publication Date Title
RU94027569A (ru) Органические соли n,n'-диацетилцистина, способ получения, фармацевтическая композиция, способы лечения
PT87542A (pt) Process for the preparation of a medicament based on indolone derivatives for the treatment of the parkinson disease
DE3862928D1 (de) Chinazolinon-derivate.
AU1578688A (en) Pharmaceutical composition, for oral administration, designed to attenuate the effects of beta-lactamines
NO166362C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive polyaminderivater.
RU93004793A (ru) Производные хиназолина, способ их получения, фармацевтическая композиция на их основе
NO871295D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
IE45989L (en) Piperidine compounds.
NO863671D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-2-heterocykloalkylpyrido(4,3)indoler.
NO870049L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO165071C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-(3-amino-1-pyrrolidinyl)-8-klor-1-cyklopropyl-6- fluor-1,4,-dihydro-4-okso-3-kinolin-karboksylsyre.
DK597687D0 (da) Imidazolidinonforbindelse, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat dermed
NO863373L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
DK447387D0 (da) Hexahydroarylquinolizinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK45385D0 (da) Hexahydroarylquinolizin og farmaceutisk praeparat indeholdende en saadanforbindelse
NO167456C (no) Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse 7-(3-amino-1-pyrrolidinyl)-8-brom-1-syklopropyl-6-fluor-1,4-dihydro-4-okso-3-quinolinkarboksylsyre
DK526087D0 (da) Antikonvulsive aminosyrederivater
NO862390D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,4-dihydropyridinderivater.
NO167801C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,2'-bi-1h-imidazolderivater.
DE3674323D1 (de) 4-methoxyisophthalsaeurederivat mit pharmakologischer wirksamkeit gegen thromboembolische erkrankung und verfahren zu dessen herstellung.
SE8305362D0 (sv) Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds
NO863005D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,4,5,6,7,8-heksahydro-2-alkyl-4-aryl-5-okso-1,7-naftyridin-3-karboksylsyreesterderivater.
RO91015B1 (ro) Solutie injectabila de uz pediatric
FR2567755B1 (fr) Nouveau medicament anti-tumoral contenant comme ingredient actif le triacetoxy-1,8,9 anthracene
BG42833A3 (en) Method for preparing of 1, 3- bis (dimethylamino)- 2- propyl- 4- chlorphenynoxyacetate

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment