DK3127542T3 - Antiviral terapi - Google Patents
Antiviral terapi Download PDFInfo
- Publication number
- DK3127542T3 DK3127542T3 DK16187411.0T DK16187411T DK3127542T3 DK 3127542 T3 DK3127542 T3 DK 3127542T3 DK 16187411 T DK16187411 T DK 16187411T DK 3127542 T3 DK3127542 T3 DK 3127542T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- pharmaceutically acceptable
- combination
- formula
- acceptable salt
- Prior art date
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- BEUUJDAEPJZWHM-COROXYKFSA-N tert-butyl n-[(2s,3s,5r)-3-hydroxy-6-[[(2s)-1-(2-methoxyethylamino)-3-methyl-1-oxobutan-2-yl]amino]-6-oxo-1-phenyl-5-[(2,3,4-trimethoxyphenyl)methyl]hexan-2-yl]carbamate Chemical compound C([C@@H]([C@@H](O)C[C@H](C(=O)N[C@H](C(=O)NCCOC)C(C)C)CC=1C(=C(OC)C(OC)=CC=1)OC)NC(=O)OC(C)(C)C)C1=CC=CC=C1 BEUUJDAEPJZWHM-COROXYKFSA-N 0.000 description 1
- 229960000838 tipranavir Drugs 0.000 description 1
- SUJUHGSWHZTSEU-FYBSXPHGSA-N tipranavir Chemical compound C([C@@]1(CCC)OC(=O)C([C@H](CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)=C(O)C1)CC1=CC=CC=C1 SUJUHGSWHZTSEU-FYBSXPHGSA-N 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
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- 229940116362 tragacanth Drugs 0.000 description 1
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- 230000003612 virological effect Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Claims (10)
1. Kombination omfattende en forbindelse givet i strukturformel (I)
eller et farmaceutisk acceptabelt salt heraf, og abacavir eller et farmaceutisk acceptabelt salt heraf.
2. Kombination ifølge krav 1, hvor det farmaceutisk acceptable salt af abacavir er hemisulfatsaltet.
3. Kombination ifølge krav 1 eller 2, hvor det farmaceutisk acceptable salt af forbindelsen set i strukturformel (I) er natriumsaltet.
4. Kombination ifølge et hvilket som helst af kravene 1-3 til anvendelse i medicinsk terapi.
5. Kombination ifølge et hvilket som helst af kravene 1-3 til anvendelse i behandlingen af HIV-infektion.
6. Farmaceutisk sammensætning omfattende en kombination ifølge et hvilket som helst af kravene 1-3 sammen med et farmaceutisk acceptabelt bærestof dertil.
7. Kombination ifølge et hvilket som helst af kravene 1-3, hvor kombinationen indgives samtidigt.
8. Kombination ifølge et hvilket som helst af kravene 1-3, hvor kombinationen indgives sekventielt.
9. Patientpakke omfattende en kombination ifølge krav 1.
10. Anvendelse af en kombination ifølge et hvilket som helst af kravene 1-3 til fremstilling af et lægemiddel til behandling af HIV-infektion.
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| US29858910P | 2010-01-27 | 2010-01-27 | |
| EP15164931.6A EP2932970B1 (en) | 2010-01-27 | 2011-01-24 | Antiviral therapy |
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| DK15164931.6T DK2932970T3 (da) | 2010-01-27 | 2011-01-24 | Antiviral terapi |
| DK11737484.3T DK2531027T3 (da) | 2010-01-27 | 2011-01-24 | Terapeutisk combination omfattende dolutegravir, abacavir og lamivudin |
| DK16187411.0T DK3127542T3 (da) | 2010-01-27 | 2011-01-24 | Antiviral terapi |
| DK19151897.6T DK3494972T3 (da) | 2010-01-27 | 2011-01-24 | Kombinationer af dolutegravir og lamivudin til behandling af HIV-infektion |
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| DK15164931.6T DK2932970T3 (da) | 2010-01-27 | 2011-01-24 | Antiviral terapi |
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| BR112015006558A2 (pt) | 2012-10-23 | 2017-07-04 | Cipla Ltd | composição farmacêutica, processo para preparar uma composição farmacêutica, uso de uma composição farmacêutica, e, método para prevenir ou tratar doenças causadas por retrovírus |
| CA3012242C (en) | 2012-12-21 | 2021-11-02 | Gilead Sciences, Inc. | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
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| CA2897137A1 (en) | 2013-02-18 | 2014-08-21 | Ratiopharm Gmbh | Solid pharmaceutical dosage form of dolutegravir |
| NO2865735T3 (da) | 2013-07-12 | 2018-07-21 | ||
| CA2916993C (en) | 2013-07-12 | 2019-01-15 | Gilead Sciences, Inc. | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
| HK1221648A1 (zh) | 2013-09-27 | 2017-06-09 | Merck Sharp & Dohme Corp. | 用作hiv整合酶抑制劑的取代喹嗪衍生物 |
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